• 재활치료과학
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• 제1권1호
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• pp.39-56
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• 2012

서론 : 동물 연구는 작업치료에 직접적으로 적용할 수 없으나, 인간을 대상으로 한 연구와 함께 작업치료의 이론과 임상에 필수적인 지식을 제공한다. 본 논문의 목적은 신경과학적 관점에서 동물모델이 작업치료의 이론과 임상에 어떠한 가능성을 가져다 줄 수 있는지를 살펴보는 것이다. 본론 : 동물 모델을 통해 얻은 지식은 뇌신경 질환의 기전과 관련된 신경 회로에 대한 이해를 돕는다. 이러한 지식을 바탕으로, 연구자들은 뇌신경 질환에 대한 여러 가지 가정들을 동물 모델을 통해 확인해 볼 수 있다. 또한, 여러 동물 실험들을 통해 쌓인 지식들은 인간에게 적용할 수 있는 새로운 치료적 접근들을 제시해 줄 수 있으며 치료에 대한 효율성을 높여줄 수 있다. 결론 : 동물 모델을 통해 얻은 지식은 뇌신경 질환의 기전과 관련된 신경 회로에 대한 이해를 돕는다. 이러한 지식을 바탕으로, 연구자들은 뇌신경 질환에 대한 여러 가지 가정들을 동물 모델을 통해 확인해 볼 수 있다. 또한, 여러 동물 실험들을 통해 쌓인 지식들은 인간에게 적용할 수 있는 새로운 치료적 접근들을 제시해 줄 수 있으며 치료에 대한 효율성을 높여줄 수 있다.

• The Journal of Advanced Prosthodontics
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• 제6권6호
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• pp.505-511
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• 2014

PURPOSE. The purpose of this study was to assess the effect of systemically administered oxytocin (OT) on the implant-bone interface by using histomorphometric analysis and the removal torque test. MATERIALS AND METHODS. A total of 10 adult, New Zealand white, female rabbits were used in this experiment. We placed 2 implants (CSM; CSM Implant, Daegu, South Korea) in each distal femoral metaphysis on both the right and left sides; the implants on both sides were placed 10 mm apart. In each rabbit, 1 implant was prepared for histomorphometric analysis and the other 3 were prepared for the removal torque test (RT). The animals received intramuscular injections of either saline (control group; 0.15 M NaCl) or OT (experimental group; $200{\mu}g/rabbit$). The injections were initiated on Day 3 following the implant surgery and were continued for 4 subsequent weeks; the injections were administered twice per day (at a 12-h interval), for 2 days per week. RESULTS. While no statistically significant difference was observed between the two groups (P=.787), the control group had stronger removal torque values. The serum OT concentration (ELISA value) was higher in the OT-treated group, although no statistically significant difference was found. Further, the histomorphometric parameter (bone-to-implant contact [BIC], inter-thread bone, and peri-implant bone) values were higher in the experimental group, but the differences were not significant. CONCLUSION. We postulate that OT supplementation via intramuscular injection weakly contributes to the bone response at the implant-bone interface in rabbits. Therefore, higher concentrations or more frequent administration of OT may be required for a greater bone response to the implant. Further studies analyzing these aspects are needed.

• 복식문화연구
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• 제10권2호
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• pp.160-177
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• 2002

Wedding ceremony is a most basic and significant rite of religion. Clothing fur the ceremony is also assumed religious in essence. Thus this study focuses on ideas and religious qualities implied in wedding dresses for women in the latter period of Chosen. Among those wedding dresses for women in the public class, in this study, Yeom-Eui(염의), Won-Sam(원삼) in green and Hwal-Ot(활옷) are discussed. Yeom-Eui seemed preferred by only some of the nobel class who still considered manners and customs as very important. The rest people often wore a brilliant Hwal-Ot rather than Yeom-Eui under influences of a loosened social position system and sumptuous moods. Since a wedding is the reflection of social condition and at the same time a religious rite, the above mentioned difference in wedding dresses between the class of scholars obsessed with Confucianism and the rest public seems attributable to differences in values and religious views between the two groups. Of course, Hwal-Ot was also transmitted from the Chinese nation of Tang, so it complied with a contemporary flunkeyism about Chinese culture. Won-Sam and Hwal-Ot were designed with patterns representing the very significance of wedding and those wishing worldly blessings more children and more sons, longevity and wealth and prosperity. The fact that wishes of more children and more sons were more often implied by patterns of wedding dress in the latter Chosen indicates the legitimate oldest son-oriented patriarchical family system at that time influenced to such contemporary dresses. Meanwhile, those patterns used for Won-Sam and Hawl-Ot were influenced mainly by Confucianism, but sometimes based on Buddhism and Taoism. It suggests that the Chosun dynasty emphasized Confucian manners and customs to restore previous values which had been about to be collapsed since wars with the Chinese Ching and Japan, but nevertheless in the public class, Buddhism and Taoism were more deeply prevailed. This was supported by patterns and colors shown in wedding clothing.

• 대한통합의학회지
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• 제9권1호
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• pp.91-100
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• 2021

Purpose : This study aims to investigate the awareness of occupational therapists among managers and directors of adult day care centers in Korea to explore the cause of the low employment rate of these therapists and offer the results as basic data that can be used to expand occupational therapy at adult day care centers. Methods : This study collected data by conducting an online questionnaire with managers and directors of adult day care centers located in Seoul, Busan, Incheon, Daejeon, Gwangju, and Ulsan. A total of 70 completed questionnaires were divided into two groups a 'group with experience in occupational therapy information (OT experience)' and a 'group with no experience in occupational therapy information (OT inexperience)' and analyzed. Results : First, the 'OT experience' was found to have higher levels of awareness of the scope of work of occupational therapists than the 'OT inexperience'. Second, significant differences were found in the degree of awareness and necessity of occupational therapists and plans to employ occupational therapists later between the 'OT experience' and the 'OT inexperience'. Third, it was shown that there were significant correlations between whether the respondents were familiar with occupational therapy and the degree of awareness and necessity of occupational therapists and plans to employ occupational therapists later. Conclusion : Based on these findings, the following measures are recommended to expand the area of occupational therapy in adult day care centers, the need for occupational therapists should be mentioned in the health and welfare-related education for workers at these adult day care centers, policies such as a medical fee system for occupational therapy at these adult day care centers should be prepared.

• 대한감각통합치료학회지
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• 제8권1호
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• pp.51-60
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• 2010

목적 : 본 연구에서는 특수교육지원센터에서 시행되는 치료지원서비스의 인식, 목적, 특징 및 개선방안을 살펴봄으 로써 치료지원서비스의 전반적 실태를 파악하고 이를 통해 최적의 치료지원서비스를 제공하기 위한 기초자료로 제시하고자 한다. 연구 방법 : 현재 특수교육지원센터에서 치료지원서비스를 받고 있는 치료지원대상 아동의 보호자를 대상으로 개별 인터뷰가 진행되었다. 인터뷰는 평균 40분이 소요되었으며, 모든 인터뷰는 녹취되었다. 결과 : 치료지원서비스에 대한 근본적인 인식이 부족하였고, 치료영역의 전문가가 치료를 담당함으로 인하여 치료사에 대한 신뢰도가 높은 것으로 조사되었다. 또한 치료실의 시설 및 교재교구의 다양성으로 인해 질적으로 높은 치료를 받는다고 생각하고 있었으며 모든 연구대상자는 무상교육을 치료지원서비스의 특징으로 꼽았다. 결론 : 작업치료사가 특수교육지원센터에서 치료지원서비스 전문가로 자리 매김하기 위해서 많은 노력과 연구 및 대외적인 홍보가 필요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.133-137
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• 2013

Background: To investigate the impact of ovarian transposition (OT) on survival rates of the patients with stage Ib squamous cell cervical cancer. Materials and Methods: Ninety-two subjects who underwent a radical hysterectomy including oophorectomy were evaluated. For nineteen (20.7%), OT was performed. Patients were divided into two groups, OT versus oophorectomy alone. The primary end-point of this study was to investigate the impact of OT on tumor recurrence rate and time, 5-year disease-free survival (DFS) and overall survival (OS). These comparisons were performed for subgroups including patients who received radiotherapy versus who did not. Statistical analyses were conducted using the Chi-square test, T-test and Mann-Whitney test. OS was examined using the Kaplan-Meier method. $P{\leq}0.05$ was considered to be statistically significant. Results: The median follow-up period was 89 months for OT and 81 months for the oophorectomy group (p>0.05). Both groups experienced similar recurrence rates (31.6% vs. 26.4%, p=0.181). The median duration from surgery to recurrence, and surgery to death were also similar between the groups (p>0.05). The 5-year DFS and OS rates were both 68.4% for the OT group, and 73.6% and 77.8% for the oophorectomy group (p=0.457 and p=0.307, respectively). While the 5-year DFS rate was not statistically significant between the OT and oophorectomy groups who did not receive radiotherapy (p=0.148), the 5-year OS rate was significantly higher in the oophorectomy group (95.4% vs 66.7%, respectively) without radiotherapy (p=0.05). The 5-year DFS and OS rates were statistically similar between the groups who received adjuvant radiotherapy (p>0.05). Conclusions: Ovarian transposition has not significantly negative effect on the survival rates when adjuvant radiotherapy will be applied, while 5-year OS may be less in OT group if radiotherapy is not mandatory.

• Tuberculosis and Respiratory Diseases
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• 제87권1호
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• pp.100-114
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• 2024

Background: Long-term oxygen therapy (LTOT) improves the survival of patients with hypoxemia due to chronic respiratory diseases. The clinical outcomes of LTOT are strongly associated with patient adherence. To improve the adherence of patients, physicians have focused on the efficacy of LTOT. However, poor adherence may stem from patients' perceptions of LTOT. Herein we evaluated patients' perceptions of LTOT affecting adherence. Methods: We conducted a cross-sectional survey study using descriptive, open, and closed-ended questionnaire. Patients using oxygen therapy (OT) or requiring it but avoiding OT responded to the questionnaires at three university hospitals. Results: Seventy-nine patients responded to the questionnaires. The number of patients using home and portable OT was 69 (93%) and 37 (46.3%), respectively. Patients with good adherence were 22 (30.1%). Among patients with good adherence, 90.9% used oxygen according to physicians' prescriptions whereas only 37.3% of those with poor adherence followed physicians' prescriptions (p<0.01). The reasons for avoiding using home OT were fear of permanent use (50%), unwanted attention (40%), and lack of symptoms (40%). They avoided portable OT because of unwanted attention (39%), heaviness (31.7%), and lack of symptoms (21.6%). Conclusion: Patients on LTOT had the perception of the misunderstanding the effects of OT and of psychosocial barriers to initiate or use LTOT. Considering these findings, health professionals need to provide effective education on the purpose of LTOT to improve patient adherence to OT and provide sufficient support for the management of psychosocial barriers in patients using LTOT.

• Biomolecules & Therapeutics
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• 제24권3호
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• pp.244-251
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• 2016

Understanding the developmental mechanisms of humoral immunity against intranasal antigens is essential for the development of therapeutic approaches against air-borne pathogens as well as allergen-induced pulmonary inflammation. Follicular helper T (Tfh) cells expressing CXCR5 are required for humoral immunity by providing IL-21 and ICOS costimulation to activated B cells. However, the regulation of Tfh cell responses against intranasal antigens remains unclear. Here, we found that the generation of Tfh cells and germinal center B cells in the bronchial lymph node against intranasal proteinase antigens was independent of $TGF-{\beta}$. In contrast, administration of STAT3 inhibitor STA-21 suppressed the generation of Tfh cells and germinal center B cells. Compared with wild-type OT-II T cells, STAT3-deficient OT-II T cells transferred into recipients lacking T cells not only showed significantly reduced frequency Tfh cells, but also induced diminished IgG as well as IgE specific for the intranasal antigens. Cotransfer study of wild-type OT-II and STAT3-deficient OT-II T cells revealed that the latter failed to differentiate into Tfh cells. These findings demonstrate that T cell-intrinsic STAT3 is required for the generation of Tfh cells to intranasal antigens and that targeting STAT3 might be an effective approach to ameliorate antibody-mediated pathology in the lung.

• 한국의류학회지
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• 제33권9호
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• pp.1386-1397
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• 2009

This study investigates costumes for ball jointed dolls under the theme of Bok-yo(服妖): The Lady in Early-middle Joseon with relic costumes as a reference. The Bok-yo style was spread universally for Joseon women in the $15^{th}-16^{th}$ centuries, but it is an uncommon theme in the area of media and traditional costume for dolls. Bok-yo (curious outfit), consisted of a Dang-jeogori with a golden brocade in the front bottom, manlike Jang-ot, wide Chima, and Jang-ot was dressed between Chima and the Dang-jeogori. To make correct patterns and approvals for idle bodies of female ball-jointed dolls, darts are added in the front vertical line and center back of the golden brocade Dan-jeogori for Joseon ladies. The pattern of the golden brocade Chima is made as a trapezoid shape for the thin waist of a doll, and the length of a deep-greened silk gauze The Jang-ot increased because of the length of the doll's legs. In addition, the kinds of investigated accessories, hair, traditional underwear for dolls are limited. Suggested is a closer cooperation between the investigated costume designers, doll companies, and accessory makers for the future market of ball jointed dolls.

• Nuclear Engineering and Technology
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• 제19권3호
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• pp.186-191
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• 1987

본 논문에서는, 임의의 계통신뢰도를 매우 단순화시킬 수 있는 직접 모의 방법을 제시하였다. 계통의 비가용도 측면에서, 본 방법은 고장수목을 하드웨어적으로 구성함으로서 계산과정을 단순화시킬 수 있었다. 계산도구로는 프랑스의 Laviron씨가 개발한 ESCAF을 사용하였다. 금번 연구에서는 PWR 발전소의 OP$\Delta$T St OT$\Delta$T 찬넬의 비가용도를 IEEE std. 500-1977의 제시된 자료를 근거로 치산하였으며, 그 값은 8.17576$\times$$10^{-9}$ 로 나타났다. 또한 계산시간은 25초 미만이었다.