• Title/Summary/Keyword: OP18

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A Study on Compensating the Errors of SCI using the Buffer Circuit (Buffer 회로를 이용한 SCI의 오차 보상에 관한 연구)

  • 오성근;김동용
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.18 no.8
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    • pp.1159-1168
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    • 1993
  • The Switched-Capacitor Integrator(SCI) is a basic building block of Switched-Scpacitor Filter(SCF). But owing to the errors from the finite gain and bandwidth of op-amp on SCI, the most of SCP are limited to their applications. Although many of the compensation methods developed for active RC filters can be directly adapted to SCF, this is not true for the analysis of the effects of the op-amp dynamics on the filter response. The effect of finite op-amp gain is similar to the active RC filters. But SCF is more toter-ant of the finite op-amp bandwidth. In this paper, we have considered the errors of the finite gain and bandwidth of op-amp on SCI , and presented the simple and effective methods of compensating the errors of SCI due to the finite op-amp gain using the buffer circuit.

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Adjoint-Based Observation Impact of Advanced Microwave Sounding Unit-A (AMSU-A) on the Short-Range Forecast in East Asia (수반 모델에 기반한 관측영향 진단법을 이용하여 동아시아 지역의 단기예보에 AMSU-A 자료 동화가 미치는 영향 분석)

  • Kim, Sung-Min;Kim, Hyun Mee
    • Atmosphere
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    • v.27 no.1
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    • pp.93-104
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    • 2017
  • The effect of Advanced Microwave Sounding Unit-A (AMSU-A) observations on the short-range forecast in East Asia (EA) was investigated for the Northern Hemispheric (NH) summer and winter months, using the Forecast Sensitivity to Observations (FSO) method. For both periods, the contribution of radiosonde (TEMP) to the EA forecast was largest, followed by AIRCRAFT, AMSU-A, Infrared Atmospheric Sounding Interferometer (IASI), and the atmospheric motion vector of Communication, Ocean and Meteorological Satellite (COMS) or Multi-functional Transport Satellite (MTSAT). The contribution of AMSU-A sensor was largely originated from the NOAA 19, NOAA 18, and MetOp-A (NOAA 19 and 18) satellites in the NH summer (winter). The contribution of AMSU-A sensor on the MetOp-A (NOAA 18 and 19) satellites was large at 00 and 12 UTC (06 and 18 UTC) analysis times, which was associated with the scanning track of four satellites. The MetOp-A provided the radiance data over the Korea Peninsula in the morning (08:00~11:30 LST), which was important to the morning forecast. In the NH summer, the channel 5 observations on MetOp-A, NOAA 18, 19 along the seaside (along the ridge of the subtropical high) increased (decreased) the forecast error slightly (largely). In the NH winter, the channel 8 observations on NOAA 18 (NOAA 15 and MetOp-A) over the Eastern China (Tibetan Plateau) decreased (increased) the forecast error. The FSO provides useful information on the effect of each AMSU-A sensor on the EA forecasts, which leads guidance to better use of AMSU-A observations for EA regional numerical weather prediction.

A 67dB DR, 1.2-V, $0.18-{\mu}m$ Sigma-Delta Modulator for WCDMA Application (WCDMA용 67-dB DR, 1.2-V, $0.18-{\mu}m$ 시그마-델타 모듈레이터 설계)

  • Kim, Hyun-Jong;Yoo, Chang-Sik
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.6 s.360
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    • pp.50-59
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    • 2007
  • [ $0.18-{\mu}m$ ] CMOS 1.2-V 2nd-order ${\Sigma}{\Delta}$ modulator with full-feedforward topology is designed. Using full-feedforward topology makes op-amp performance requirements much less stringent, therefore it has been adopted as a good candidate for low-voltage low-power applications throughout the world. Also, ${\Sigma}{\Delta}$ modulator is designed with top-down design approach, therefore various nonideal effects of op-amp are modeled in this paper.

Organ preservation with neoadjuvant chemoradiation in patients with orbit invasive sinonasal cancer otherwise requiring exenteration

  • Amsbaugh, Mark J.;Yusuf, Mehran;Silverman, Craig;Bumpous, Jeffrey;Perez, Cesar A.;Potts, Keven;Tennant, Paul;Redman, Rebecca;Dunlap, Neal
    • Radiation Oncology Journal
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    • v.34 no.3
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    • pp.209-215
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    • 2016
  • Purpose: We sought to determine if organ preservation (OP) with neoadjuvant chemoradiation (CRT) was feasible in patients with sinonasal cancer determined to require exenteration. Materials and Methods: Twenty patients were determined to require exenteration for definitive treatment from 2005 to 2014. Fourteen patients underwent OP and 6 patients received exenteration with adjuvant CRT. Exenteration free survival (EFS), locoregional control (LRC), progression-free survival (PFS), and overall survival (OS) were estimated. Results: Five patients (36%) receiving OP had complete disease response at time of surgery. With a median follow-up of 18.8 months, EFS was 62% at 2 years for patients undergoing OP. At 2 years, there were no significant differences in LRC, PFS or OS (all all p > 0.050) between the groups. Less grade 3 or greater toxicity was seen in patients undergoing OP (p = 0.003). Visual function was preserved in all patients undergoing OP. Conclusion: For patients with sinonasal cancer, OP may avoid exenteration, offering similar disease control and improved toxicity.

Determination of alkylphenol ethoxylate in water by high performance liquid chromatography/electrospray ionization/mass spectrometry (HPLC/ESI/MS를 이용한 물 중의 알킬페놀에톡실레이트 분석)

  • Lee, Jeongae;Park, Song-Ja;Chung, Bong Chul
    • Analytical Science and Technology
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    • v.17 no.3
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    • pp.263-270
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    • 2004
  • A method is described for the analysis of short-chain alkylphenol ethoxylates (APEOs), 4-octylphenol-di-ethoxylate (OP2EO) and 4-nonylphenol-di-ethoxylate (NP2EO), in drinking water or wastewater using reversed phase high-performance liquid chromatography with electrospray ionization mass spectrometry. The solvent system was water and methanol containing $10{\mu}M$ trifluoroacetic acid as an ionization solvent. We acidified 1 L of water samples to less than pH 2 with concentrated $H_2SO_4$ and loaded onto Sep-Pak $C_{18}$, and eluted with acetone. The calibration of OP2EO and NP2EO was performed for the concentration range from 20 to 500 ng/L and the correlation coefficients were 0.999 and 0.990, respectively. The limits of detection were 20 ng/L (OP2EO) and 50 ng/L (NP2EO) at a signal-to-noise ratio of 3. Accuracy and precision of this analytical method were 85.8 ~ 122.1% and 8.2 ~ 18.8%, respectively. The proposed method allowed a sensitive and rapid detection of OP2EO and NP2EO and it could be applied for monitoring of APEOs from environmental samples.

A Comparative Evaluation of $K_{op}$ Determination and $\Delta{K}_{eff}$ Estimation Methods

  • Kang, Jae-Youn;Song, Ji-Ho;Koo, Ja-Suk;Park, Byung-Ik
    • Journal of Mechanical Science and Technology
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    • v.18 no.6
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    • pp.961-971
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    • 2004
  • Methods for determination of the crack opening stress intensity factor ($K_{op}$) and for estimation of the effective stress intensity factor range ($\Delta{K}_{eff}$) are evaluated for crack growth test data of aluminum alloys. Three methods of determining $K_{op}$, visual measurement, ASTM offset compliance method, and the neural network method proposed by Kang and Song, and three methods of estimating $\Delta{K}_{eff}$, conventional, the 2/PIO and 2/PI methods proposed by Donald and Paris, are compared in a quantitative manner by using evaluation criteria. For all $K_{op}$ determination methods discussed, the 2/PI method of estimating $\Delta{K}_{eff}$ provides good results. The neural network method of determining $K_{op}$ provides good correlation of crack growth data. It is recommended to use 2/PI estimation with the neural $K_{op}$ determination method. The ASTM offset method used in conjunction with 2/PI estimation shows a possibility of successful application. It is desired to improve the ASTM method.

Influence of Thickness of Optical Panel on the Growth Rate of Chlorella vulgaris in Photobioreactor (광생물반응기에서 도광판의 두께가 Chlorella vulgaris 증식에 미치는 영향)

  • Choi, Hee-Jeong;Lee, Seung-Mok
    • Journal of Korean Society on Water Environment
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    • v.29 no.2
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    • pp.270-275
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    • 2013
  • The aim of this study was to investigate the efficiency of thickness of optical panel (OP) on the growth rate of Chlorella vulgaris. The size of Chlorella vulgaris (FC-16) was $3-8{\mu}m$, having round in shape. The cells of Chlorella vulgaris was cultured in the Jaworski's Medium with deionized water at $22^{\circ}C$ for 15 days. For this experiment, three OP samples were prepared to evaluate the efficiency of thickness of OP on the growth rate of Chlorella vulgaris; 4 mm OP with LED (Light Emitting Diode) (Run 1), 6 mm OP with LED (Run 2) and 8 mm with LED (Run 3). The diffuse rate was reached 86%, 91% and 92% for Run 1, Run 2 and Run 3, respectively. Average biomass of Run 2 and Run 3 were measured 11.18% higher than that of Run 1. However, the specific growth rate for all fractions were almost same. In addition, chlorophyll content per cell and cell volume were found to be slice difference between Run 2 and Run 3. Therefore, Run 2 has more effect on growth rate of biomass for Chlorella vulgaris than Run 1 and Run 3.

Comparative Analysis between Preoperative Radiotherapy and Postoperative Radiotherapy in Clinical Stage I and II Endometrial Carcinoma (자궁내막암 환자에서 수술 전 방사선치료와 수술 후 방사선치료의 성적 비교 분석)

  • Keum Ki Chang;Lee Chang Geol;Chung Eun Ji;Lee Sang Wook;Kim Woo Cheol;Chang Sei Kyung;Oh Young Taek;Suh Chang Ok;Kim Gwi Eon
    • Radiation Oncology Journal
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    • v.13 no.4
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    • pp.377-383
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    • 1995
  • Purpose : To obtain the optimal treatement method in patients with endometrial carcinoma(clinical stage FIGO I, II) by comparative analysis between preoperative radiotherapy (pre-op RT) and postoperative radiotherapy (post-op RT). Material and Methods : A retrospective review of 62 endometrial carcinoma patients referred to the Yonsei Cancer Center for radiotherapy between 1985 and 1991 was undertaken. Of 62 patients, 19 patients(Stagel : 12 patients. Stagell;7 patients) received pre-op RT before TAH(Total Abdominal Hysterectomy) and BSO (Bilateral Salphingoophorectomy) (Group 1) and 43 patients(Stage 1;32 patients, Stage 2; 11 patients) received post-op RT after TAH and BSO (Group 2). Pre-op irradiation was given 4-6 weeks prior to surgery and post-op RT administered on 4-5 weeks following surgery. All patients except 1 patient(Group 2: ICR alone) received external irradiation. Seventy percent(13/19) of pre-op RT group and 54 percent(23/42) of post-op RT group received external pelvic irradiation and intracavitary radiation therapy(ICR). External radiation dose was 39.6-55 Gy(median 45 Gy) in 5-6. 5weeks through opposed AP/PA fields or 4-field box technique treating daily, five days per week, 180 cGy per fraction. ICR doses were prescribed to point A(20-39.6 Gy, median 39 Gy) in Group 1 and 0.5cm depth from vaginal surface (18-30 Gy,median 21 Gy) in Group 2. Results : The overall 5 year survival rate was $95{\%}$. No survival difference between pre-op and post-op RT group.($89.3{\%}$ vs $97.7{\%}$, p>0.1) There was no survival difference by stage, grade and histology between two groups. The survival rate was not affected by presence of residual tumor of surgical specimen after pre-op RT in Group 1 (p>0.1), but affected by presence of lymph node metastasis in post-op RT group(P<0.5). The complication rate of pre-op RT group was higher than post-op RT. ($16{\%}$ vs $5{\%}$) Conclusion : Post-op radiotherapy offers the advantages of accurate surgical-pathological staging and low complication rate.

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Effects of Maternal Exposure to Xenoestrogens on the Steroidogenesis in Mouse Testis of Male Offspring

  • An, Su-Yeon;Lee, Hoon-Taek;Kim, Suel-Kee;Yoon, Yong-Dal;Lee, Ho-Joon
    • Proceedings of the KSAR Conference
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    • 2003.06a
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    • pp.31-31
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    • 2003
  • The incidence of reproductive abnormalities in the male has been reported to have increased during the past 50 years. These changes may be attributable to the presence of chemical with oestrogenic activity in our environment. Present study was carried out to determine the effects of maternal exposure to xenoestrogens on the testicular development and on the transcriptional expression of the steroidogenic enzyme and subunits of inhibin/activin in testis of male offspring. Pregnant female mice were administrated with 4-tert-octylphenol (OP; 2, 20, 200mg/kg), Bisphenol A (BPA; 2, 20, 200$\mu\textrm{g}$/kg), $\beta$-estradiol 17-valerate (EV; 2$\mu\textrm{g}$/kg) or vehicle (CV; corn oil) during gestational days 11 to 17. Offsprings were sacrificed on gestational day 18 (fetal 18) and neonatal day 7. Body weights were significantly increased in groups treated with all doses of OP and BPA. Maximum seminiferous tubules diameter on gestational day 18 were not changed in any treatment group, however, they were significantly increased on the neonatal day 7 in the group treated with low-dose of OP (2 mg/kg) and BPA (2 $\mu\textrm{g}$/kg). Increased expression of the P450$_{17a}$-hydroxylase dehydrogenase (P450$_{17a}$), 3$\beta$-hydroxylase dehydrogenase (3$\beta$-HSD), and 17$\beta$-hydroxylase dehydrogenase (17$\beta$-HSD) on gestational day 18 were observed in the groups treated with 2 or 20 mg/kg of OP. However, expression of the steroidogenic enzymes were not changed in the groups treated with all the doses of BPA. In contrast with the results from fetal testis, no expressional changes of these enzymes was found in all the OP-treated group and increased expression of inhibin/activin $\beta$B subunit mRNA were obseued in the 200 $\mu\textrm{g}$/kg BPA-treated group in the neonatal day 7. These results suggest that gestational exposure to low level of xenoestrogen causes a stimulatory effects on the transcriptional expressions of steroidogenic enzymes and subunits of inhibin/activin and on the seminiferous tubule development by their estrogen-like actions.ons.

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