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Influences of ethanol and temperature on sucrose-evoked response of gustatory neurons in the hamster solitary nucleus

  • Li, Cheng-Shu;Chung, Ki-Myung;Kim, Kyung-Nyun;Cho, Young-Kyung
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.6
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    • pp.603-611
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    • 2021
  • Taste-responsive neurons in the nucleus of the solitary tract (NST), the first gustatory nucleus, often respond to thermal or mechanical stimulation. Alcohol, not a typical taste modality, is a rewarding stimulus. In this study, we aimed to investigate the effects of ethanol (EtOH) and/or temperature as stimuli to the tongue on the activity of taste-responsive neurons in hamster NST. In the first set of experiments, we recorded the activity of 113 gustatory NST neurons in urethane-anesthetized hamsters and evaluated responses to four basic taste stimuli, 25% EtOH, and 40℃ and 4℃ distilled water (dH2O). Sixty cells responded to 25% EtOH, with most of them also being sucrose sensitive. The response to 25% EtOH was significantly correlated with the sucrose-evoked response. A significant correlation was also observed between sucrose- and 40℃ dH2O- and between 25% EtOH- and 40℃ dH2O-evoked firings. In a subset of the cells, we evaluated neuronal activities in response to a series of EtOH concentrations, alone and in combination with 32 mM sucrose (EtOH/Suc) at room temperature (RT, 22℃-23℃), 40℃, and 4℃. Neuronal responses to EtOH at RT and 40℃ increased as the concentrations increased. The firing rates to EtOH/Suc were greater than those to EtOH or sucrose alone. The responses were enhanced when solutions were applied at 40℃ but diminished at 4℃. In summary, EtOH activates most sucrose-responsive NST gustatory cells, and the concomitant presence of sucrose or warm temperatures enhance this response. Our findings may contribute to elucidate the neural mechanisms underlying appetitive alcohol consumption.

Preparation of $\delta$-FeOOH by Coprecipitation Method and Its Magnetic Properties (공침법에 의한 $\delta$-FeOOH의 제조 및 자기 특성)

  • 김성재;김태옥
    • Journal of the Korean Ceramic Society
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    • v.33 no.3
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    • pp.327-331
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    • 1996
  • $\delta$-FeOOH was prepared by rapid oxidation method of Fe(OH)2 using H2O2. The effects of reaction temperature and mole ratio ([OH-]/[Fe2+])의 몰비를 제조 변수로 하여 최종 생성된 $\delta$-FeOOH의 입자크기 입자형태, 자기특성을 조사하였다. Fe(OH)2 의 반응온도 및 [OH-]/[Fe2+] 비가 $\delta$-FeOOH의 입자크기 및 형상에 많은 영향을 미침을 알수 있었으며 입자 크기는 이 두인자에 비례하여 증가하였다 Fe(OH)2 의 반응온도가 4$0^{\circ}C$ [OH-]/[Fe2+]=5 Fe(OH)2 숙성 시간 2시간에서 제조된 $\delta$-FeOOH를 TEM, VSM으로 입자의 크기 및 자기특성을 조사한결과 평균 입경이 630$\AA$ 정도이고 입도 분포가 양호하였으며 포화자화 및 보자력은 각각 20.8emu/g 210 Oe였다.

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Studies on the Hexagonal Ferrite(IV) -The Formation Process of the Hexagonal Ferrites During Calcining the Mixture of $Ba(OH)_2$, $Zn(OH)_2$ and $6Fe(OH)_3$- (Hexagonal Ferrite에 관한 연구 (IV) -혼합수산화물로부터 각종 Hexagonal Ferrite 의 생성과정에 관한 연구-)

  • 김태옥
    • Journal of the Korean Ceramic Society
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    • v.17 no.3
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    • pp.121-128
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    • 1980
  • In order to obtain the fundamental data for the preparation of ferroxplana $Zn_2Y(Ba_2Zn_2Fe_{12}O_{22})$, which is useful for GHz-band communication, the optimum coprecipitation condition of $Zn(NO_3)_2-6FeCl_3$ in $NH_4OH$ solution and the formation process of the hexagonal ferrite were investigated. By the hot-petroleum-drying and calcining the coprecipitated hydroxide mixture $Zn(OH)_2 +Ba(OH)_2+ 6Fe(OH)_3$, the fine and uniform powder was obtained , whose phase composition and microstructure were studied by X.R.D. and electron microscope. In results, it was found that $Zn_2Y$, BaM and $Zn_2W$ were the representative phases in calcined specimens whose activation energies of crystal growth were about 3, 8, 2.5, $5.4{\times}10^4$ J/mole , respectively. The sintered specimens would be appreciated as useful magnetic cores for the high frequency communication.

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LIF/PLIF Measurements of OH Concentration in Flames (LIF/PLIF를 이용한 화염에서의 OH농도 측정)

  • 이원남
    • Journal of the KSME
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    • v.33 no.12
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    • pp.1031-1042
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    • 1993
  • 연소현상에 대한 이해를 증가시키기 위하여 화염을 이용한 많은 실험적 연구가 이루어져 왔다. 특히 연소 모델의 개선과 증명을 위하여는 화염에서의 성분 농도 측정이 필수적이며, 최근에 들어 측정 가능해진 래디컬성분의 측정은 연소해석분야에 많은 진전을 가져왔다. OH, H 및 O는 연료의 분해 (decomposition) 및 연소 산화물생성 이외에도 CO와 NO 같은 공해물질의 형성등 연소과정에서 매우 중요한 래디컬들이며, 특히 화염영역에서의 OH의 전파(transport)는 화염의 점화 및 안정성 (stability)에도 큰 영향을 미친다. OH래디컬은 연소과정에서 가장 중요한 성분 중 하나이며, 또한 스펙트럼이 비교적 잘 알려져 있어 레이저 유도 형광의 적용이 용이하므로 화염에서의 OH농도 측정에 LIF(laser induced fluorescence) 또는 PLIF(planar laser induced fluorescence)가 널리 사용되고 있다. 따라서 LIF 및 PLIF의 원리 및 연소분야에서의 응용을 OH농도 측정을 중심으로 소개하고자 한다.

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Effects of Environmental Variables on Hydrogen Generation from Alkaline Solutions using used Aluminum Cans (알칼리 용액에서 알루미늄 재활용 캔을 이용한 수소생산에 미치는 환경 인자의 영향)

  • Yun, Kwi-Sub;Park, Chan-Jin
    • Transactions of the Korean hydrogen and new energy society
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    • v.22 no.1
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    • pp.29-34
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    • 2011
  • This study examined the effect of environmental variables, such as the NaOH concentration and solution temperature, on the rate of hydrogen generation from NaOH solutions through the corrosion of used aluminum cans as a potential candidate material for the safe and economic production of hydrogen. Corrosion of the used aluminum cans was promoted by increasing the NaOH concentration and solution temperature because of the loss of aluminum passivity. The measured rate of hydrogen generation from the NaOH solutions increased with increasing NaOH concentration due to the catalytic activity of NaOH in the hydrolysis process. However, at higher solution temperatures, the rate of hydrogen generation rate was less affected by the NaOH concentration than that at lower temperature.

알칼리 수산화물에서 핵연료피복관용 Zr합금의 부식거동

  • 정용환
    • Proceedings of the Korean Nuclear Society Conference
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    • 1995.05a
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    • pp.759-764
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    • 1995
  • 여러 가지 Zr합금의 부식거동을 LiOH, NaOH, KOH, RbOH, CsOH 용액조건에서 autoclave를 이용하여 조사하였다. 용액내의 알칼리 농도는 0.3mmol 4.3mmol 31.5mmo1를 선택하였는데, 이는 Li의 경우에 2.2ppm 30ppm, 220ppm에 해당되는 농도이다. Zr합금은 ZrSn-TRM(천이원소)과 ZrSnNb-TRM(천이원소)의 두 종류의 합금을 사용하였다. 알칼리 분위기에서 Zr함금의 부식을 지배하는 이온은 양이 온인 것으로 밝혀졌으며, 양이온의 반경이 Zr합금의 천이전 영역에서의 부식을 지배하는 것으로 나타났다. Nb첨가 합금은 Zircaloy형 합금보다 내식성이 떨어진다. LiOH가 부식을 가장 가속시키는 알칼리로 밝혀졌으며 CsOH나 KOH는 거의 Zr합금의 부식을 가속시키지 않는다. 따라서 CsOH나 KOH는 PWR에 적응 가능한 대체 알칼리로서 가능성을 보였다.

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Monte Carlo Simulation for Vapor-Liquid Equilibrium of Binary Mixtures CO2/CH3OHCO2/C2 H5OH, and CO2/CH3CH2CH2OH

  • Moon, Sung-Doo
    • Bulletin of the Korean Chemical Society
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    • v.23 no.6
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    • pp.811-817
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    • 2002
  • Gibbs ensemble Monte Carlo simulations were performed to calculate the vapor-liquid coexistence properties for the binary mixtures $CO_2/CH_3OH$, $CO_2/C_2H_5OH$, and $CO_2/CH_3CH_2CH_2OH.$ The configurational bias Monte Carlo method was used in the simulation of alcohol. Density of the mixture, composition of the mixture, the pressure-composition diagram, and the radial distribution function were calculated at vapor-liquid equilibrium. The composition and the density of both vapor and liquid from simulation agree considerably well with the experimental values over a wide range of pressures. The radial distribution functions in the liquid mixtures show that $CO_2$ molecules interact more stogly with methyl group than methylene group of $C_2H_5OH$ and $CH_3CH_2CH_2OH$ due to the steric effects of the alcohol molecules.

Anti-Flammability for EEA-VLDPE compound using $Mg(OH)_2$ (EEA-VLDPE compound의 $Mg(OH)_2$ 혼합에 의한 난연성)

  • 이상석;김경태;원성호;김장규;김남기
    • Journal of the Korean Society of Safety
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    • v.13 no.3
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    • pp.96-101
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    • 1998
  • In order to study the change in mechanical properties and anti-flammablilty of ethylene-ethylacrylate copolymer(EEA) very low density polyethylene(VLDPE) compound that could be used as communication cable sheath using $Mg(OH)_2$ as a non-toxic flame retardant, 100, 125, and 150phr $Mg(OH)_2$ were added to 100 parts of EEA-VLDPE compound, 100 EEA : 0 VLDPE, 50 EEA : 50 VLDPE, and 0 EEA : 100 VLDPE, respectively. $Mg(OH)_2$ was a good non-toxic flame retardant for communication cable sheath and anti-flammability increased with the amount of $Mg(OH)_2$ in compound. The mechanical properties-MI, Ts, and Eb-decreased with increasing in the mixing ratio of EEA but oxygen index(OI) increased with increasing in the amount of EEA. The best composition of $Mg(OH)_2$ in this study was 150phr to 50 EEA : 50 VLDPE compound for the anti-flammability.

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Effects of sodium hydroxide cleaning on polyvinylidene fluoride fouled with humic water

  • Jang, Yoon-sung;Kweon, JiHyang;Kang, Min-goo;Park, Jungsu;Jung, Jae Hyun;Ryu, JunHee
    • Membrane and Water Treatment
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    • v.8 no.2
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    • pp.149-160
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    • 2017
  • This study investigated effects of NaOH cleaning on the intrinsic permeability of polyvinylidene fluoride (PVDF) membranes and flux recoveries and membrane resistances under various conditions encountered during ultrafiltration in water treatment plants. The NaOH cleaning using 10,000 mg/L NaOH led to discoloration of PVDF membranes and had little effect on water flux. The NaOH cleaning was efficient in removing the fouling layer caused by humic water. However, long filtration induced a fouling layer that was not removed easily by NaOH cleaning. The lower temperature during filtration yielded rapid increases in transmembrane pressure and decreases in NaOH cleaning efficiency. The alkaline cleaning of PVDF changed the membrane properties such as the hydrophobicity and morphology. Foulant properties, operational conditions such as temperature, and chemical agents should be considered for cleaning strategies for PVDF applied in water treatment.

Poly(vinyl alcohol)의 합성과 유변학적 성질

  • Lee, Jeong Kyung;Lee, Hyang Aee;Kim, Keyn Gyi
    • Journal of the Korean Chemical Society
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    • v.45 no.6
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    • pp.555-561
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    • 2001
  • Vinyl acetate usually used in PVA resin preparation was converted to PVAc by bulk polymerization using AIBN as a initiator and PVA was synthesized by changing the concentration of NaOH added for saponification subsequently. As a result of estimating molecular weight using GPC, molecular weight increased as the NaOH concentration increased to 2.5 N, 5.0 N, 7.5 N and 10.0 N and polydispersity had similar values of 2.1~2.3, however, showed slightly decreasing tendency. In addition, PVA saponificated by 10.0 N-NaOH showed high syndiotacticity in observation of tacticity using NMR spectroscopy. From this fact, the degree of tacticity was predicted to be high and it was in good agreement with the tendency of polydispersity by GPC. Also, from the result of FT-IR spectroscopy, it might be known that hydrolysis was more promoted in the PVA with 10.0 N-NaOH than other NaOH concentration. Intrinsic viscosity measured using Ubbelohde viscometer, which increased as the concentration of NaOH added for saponification increased. The change of shear strength with the change of shear rate was investigated using Brookfield viscometer, in consequence, viscosity of PVA synthesized decreased as shear rate increased. PVA solution confirmed to show the shear thining behavior by Casson plot and PVA with 10.0 N-NaOH had the largest yield value. DSC measurement was performed to know the thermal properties of PVA. Tp had nearly constant value of 214$^{\circ}C$ in all cases except for adding 2.5 N-NaOH and $\Delta$H was increased as the concentration of NaOH increased. From this properties, it was concluded that the degree of hydrogen bonding was proportional to the added concentration of NaOH and the increase of the degree of hydrogen bonding and hydrophobic interaction could affect the rheological and thermal properties of title compound.

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