• Title/Summary/Keyword: ODF

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Ectopic Expression of Cenexin1 S796A Mutant in $ODF2^{+/-}$ Knockout Background Causes a Sperm Tail Development Defect

  • Lee, Kyung Ho
    • Development and Reproduction
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    • v.16 no.4
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    • pp.363-370
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    • 2012
  • The outer dense fiber 2 (ODF2) protein is an important component of sperm tail outer dense fiber and localizes at the centrosome. It has been reported that the RO072 ES cell derived homozygote knock out of ODF2 results in an embryonic lethal phenotype, and XL169 ES cell derived heterozygote knock out causes severe defects in sperm tail development. The ODF2s splicing variant, Cenexin1, possesses a C-terminal extension, and the phosphorylation of serine 796 residue in an extended C-terminal is responsible for Plk1 binding. Cenexin1 assembles ninein and causes ciliogenesis in early stages of the cell cycle in a Plk1-independent manner. Alternatively, in the late stages of the cell cycle, G2/M phase, Cenexin1 binds to Plk1 and results in proper mitotic progression. In this study, to identify the in vivo function of Plk1 binding to phosphorylated Cenexin1 S796 residue, and to understand the in vivo functional differences between ODF2 and Cenexin1, we generated ODF2/Cenexin1 S796A/Cenexin1 WT expressing transgenic mice in a RO072 ES cell derived $ODF2^{+/-}$ knock out background. We observed a severe defect of sperm tail development by ectopic expression of Cenexin1 S796A mutant and no phenotypic differences between the ectopic expression of ODF2/Cenexin1 WT in $ODF2^{+/-}$ background and in normal wild type mice.

Optimized Method of Material Matching Test for Mobile ODF TFT-Panel

  • Lim, Jun-Hwan;Qiu, Yun;Zhang, Junrui;Ko, Young-Yik;Jung, Hee-Chul;Hwang, Soo-Woong
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.1596-1599
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    • 2009
  • Mobile ODF (one drop filling) portable display such as mobile phone and application product is needed high reliability than notebook, monitor and TV. Therefore, material development in order to optimize mobile & application ODF panel is needed. Through considering mobile ODF process and design, we have developed method of material matching test by several tests which is heat stress, UV stress and ODF process condition. So we have developed a material with characteristics of high reliability for mobile ODF panel.

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Redesigning Electronic Records Preservation Formats Based on Open Formats (공개포맷에 기반한 전자기록 보존 포맷 재설계 방향 연구)

  • Oh, Seh-La;Jung, Mi Ri;Yim, Jin Hee
    • Journal of Korean Society of Archives and Records Management
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    • v.16 no.4
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    • pp.79-120
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    • 2016
  • Along with the changing computing environment, the production of public documents is moving to G-Cloud and On-nara System, which are re-engineered on G-Cloud. In this process, it is predicted that the Open Document Format (ODF) will replace the proprietary document format, HWP, and will become widely used in the near future. To preserve digital records produced in ODF, this study reviewed the current long-term preservation strategies and identified considerations for new formats. For ODF source files, it is suggested to eliminate the conversion to PDF/A-1 and preserve the documents in the extended ODF with added metadata of records management. Moreover, ODF is presented as an alternative format for preserving proprietary formats. Finally, this study reviewed the current long-term preservation format, i.e., NEO, and suggests a zipped BagIt package, which has an ISO 21320 specification.

Expression of Osteoprotegerin and Osteoclast Differentiation Factor in Human Periodontal Ligament Fibroblast Cells (치주인대 섬유아세포에서 Osteoprotegerin과 Osteoclast Differentiation Factor의 발현)

  • Rew, Seong-Hun;Heo, Soo-Rew;Kim, Hyung-Seop;O, Kwi-Ok
    • Journal of Periodontal and Implant Science
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    • v.32 no.4
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    • pp.721-731
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    • 2002
  • Recently, soluble TNF receptor homolog osteoprotegerin(OPG) and its membrane-bound ligand osteoclast differentiation factor(ODF) were found to regulate osteoclast formation and function, and bone metabolism. It is now well established that ODF acts via RANK expressed on hematopoietic osteoclast precursor cells to facilitate their differentiation to osteoclasts, and OPG prevents the formation of osteoclasts by interfering the binding of ODF and RANK. Expression of OPG and ODF was believed to be closely related to the pathogenesis of bone resorption and destruction from osteoporosis, periodontal diseases, malignant bone tumor, and arthritis. The periodontal ligament fibroblasts (PDLF), located between the tooth and tooth socket, has been thought to play an important role in maintaining bone homeostasis of periodontal tissues. However, the exact mechanism by which bone formation and resorption are regulated by PDLF is not well understood. In this study we have prepared primary cultures of human PDLF from periodontium of malaligned tooth extracted due to orthodontic reason, and determined steady state or inflammatory signal-induced OPG and ODF expression using RT-PCR and western blot analysis. OPG and ODF mRNA and protein were expressed constitutively in the PDLF and these expression were slightly increased by osteotropic cytokine IL-1 ${\beta}$. Lipopolysaccharide-treated PDLF showed decrease in OPG mRNA and protein expression, and increase in ODF mRNA and protein expression. These results indicated that PDLF influence the osteoclastogenesis by OPG and ODF expression in the inflammatory situation as well as physiological condition, and thereby pathogenesis of periodontal alveolar bone destruction.

Analysis File Format of Seogwang Document Processor 3.0 in North Korea (북한 서광사무처리 3.0 파일 구조 분석)

  • Choi, Junhyeong;Kang, Dongsu
    • Proceedings of the Korea Information Processing Society Conference
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    • 2019.05a
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    • pp.335-338
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    • 2019
  • 북한에서 운영하고 있는 오피스 프로그램인 서광사무처리 3.0은 ODF(Open Document Format) 파일 포맷을 입력으로 받아 문서를 처리한다. ODF는 여러 개의 XML(Extensible Markup Language) 파일로 구성되어 있고, 하위 노드들을 통해서 파일 구조를 정의한다. 이러한 서광사무처리 3.0의 ODF 파일 구조를 하위 프로그램별 입력받는 파일 확장자에 따라 공통 영역과 가변 영역으로 비교하고, CVE(Common Vulnerabilities and Exposures)를 통해 ODF와 XML 주요 취약점을 분석한다.

The effects of sex hormones on the expression of ODF and OPG in human gingival fibroblast and periodontal ligament cell at normal menstruation cycle and menopause.

  • Shin, Ji-Yearn;Baek, Dong-Heon;Han, Soo-Boo
    • International Journal of Oral Biology
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    • v.32 no.2
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    • pp.67-73
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    • 2007
  • Periodontitis is a chronic infectious disease that leads to periodontal destruction, and is one of the major causes of tooth loss in humans. The osteoclast differentiation factor (ODF), which is also known as the receptor activator of the NF-kB ligand (RANKL), is a surface-associated ligand on bone marrow stromal cells and osteoblasts. RANKL activates its cognate receptor, RANK, on osteoclast progenitor cells, which leads to the differentiation of mononucleated precursor cells. Osteoprotegerin (OPG) is a decoy receptor that is released from stromal cells and osteoblasts to inhibit the interaction between RANKL and RANK. Although the precise mechanism of bone loss in periodontitis is unknown, the differentiation and activation of osteoclasts by OPG-ODF-RANK signaling might play the role in periodontal bone destruction. The relationship between the concentration of sex hormones and the expression of ODF and OPG was examined by treating human gingival fibroblasts and periodontal ligament cells with the normal serum concentration of estrogen or progesterone during menstruation or at menopause. The ODF/OPG relative ratio was elevated at the concentration observed during ovulation in human gingival fibroblasts and at the concentration observed between ovulation and menstruation in periodontal ligament cells treated with estrogen. However, the ratio was <1 at all concentrations in both cells treated with progesterone. In the case of menopause simulated by estrogen depletion, the ratio was <1 in human gingival fibroblasts but >1 in periodontal ligament cells.

Automatic Object Recognition in 3D Measuring Data (3차원 측정점으로부터의 객체 자동인식)

  • Ahn, Sung-Joon
    • The KIPS Transactions:PartB
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    • v.16B no.1
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    • pp.47-54
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    • 2009
  • Automatic object recognition in 3D measuring data is of great interest in many application fields e.g. computer vision, reverse engineering and digital factory. In this paper we present a software tool for a fully automatic object detection and parameter estimation in unordered and noisy point clouds with a large number of data points. The software consists of three interactive modules each for model selection, point segmentation and model fitting, in which the orthogonal distance fitting (ODF) plays an important role. The ODF algorithms estimate model parameters by minimizing the square sum of the shortest distances between model feature and measurement points. The local quadric surface fitted through ODF to a randomly touched small initial patch of the point cloud provides the necessary initial information for the overall procedures of model selection, point segmentation and model fitting. The performance of the presented software tool will be demonstrated by applying to point clouds.

Comparison of Nutritive Values of Diets Collected from Organic Dairy Farms and Conventional Dairy Farms from Chungnam and Jeonbuk in Korea (국내 일반 및 유기우유 생산농가의 착유우 급여 사료내 성분 비교)

  • Ki, Kwang Seok;Lim, Dong Hyun;Kim, Tae Il;Park, Seong Min;Lim, Hyun Joo;Choi, Ki Choon
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.1
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    • pp.29-33
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    • 2016
  • In order to provide basic data to predict changes of milk components in milk yield, this study was conducted to compare nutritive values of diets collected from organic dairy farms (ODF) and conventional dairy farms (CDF) of Chungnam and Jeonbuk in Korea. The contents of crude fat, crude fiver, neutral detergent fiber, and acid detergent fiber in diets of ODF were significantly (p<0.05) higher compared to those of CDF. The contents of crude protein and crude ash in ODF were also higher (p<0.05) than those of CDF. The contents of calcium, ferrum, and phosphorus in diets of ODF were similar to those of CDF. The contents of potassium, magnesium, and iodine in diets of ODF were higher (p<0.05) than those of CDF. The contents of total saturated and unsaturated fatty acids in diets of ODF were higher (p<0.05) compared to those of CDF. The contents of oleic acid, linoleic acid, and linolenic acid in diets of ODF were higher (p<0.05) compared to those of CDF. However, the contents of myristic acid, palmitic acid, and stearic acid in diets of ODF were lower (p<0.05) compared to those of CDF.

The Effects of Sex Hormones on the Expression of ODF/OPG in Human Gingival Fibroblast and Periodontal Ligament Cell at Serum Concentration During Pregnancy

  • Shin, Ji-Yearn;Baek, Dong-Heon;Han, Soo-Boo
    • International Journal of Oral Biology
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    • v.30 no.3
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    • pp.105-110
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    • 2005
  • Periodontitis is a chronic infectious disease that leads to the destruction, one of the major cause of tooth loss in human. Osteoclast Differentiation Factor(ODF), also called as Receptor activator of NF-${\kappa}B$ ligand(RANKL), a surface-associated ligand on bone marrow stromal cells and osteoblasts, activates its cognate receptor RANK on osteoclast progenitor cells, which leads to differentiation of these mononucleated precursor cells. Osteoprotegerin(OPG), a decoy receptor, is released from stromal cells and osteoblasts to inhibit the interaction between RANKL and RANK. The experiment for the effect of pregnancy on gingival health showed greater gingival inflammation and edema during pregnancy, despite similar plaque index. There should be many factors affecting the periodontal health in pregnancy. In this experiment, we examined the direct effects of sex hormones(estrogen and progesterone) on the ODF/OPG expression in human gingival fibroblasts and periodontal ligament cells at the serum concentration of pregnancy. The ratio was high in the 1st trimester of pregnancy by estrogen and in the late 2nd trimester by progesterone. Therefore, the local periodontal destruction might be accelerated by these hormonal effect on the periodontal cells.

삼성의 LCD-SPVA 및 -PSVA모드 개발사(開發史)와 액정주입 ODF 공정

  • Yu, Jae-Jin;Sin, Seong-Tae
    • Information Display
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    • v.22 no.4
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    • pp.34-44
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    • 2021
  • 90년대 초 LCD (Liquid Crystal Display)는 연관된 반도체 산업과 함께 제2산업의 쌀로 불리며 정부와 관련업계의 높은 관심 속에 큰 성장을 이루었다. 삼성은 일본 기업에 비해 LCD 개발을 늦게 시작했지만 패널 대형화와 넓은 광시야각을 구현한 PVA (Patterned Vertical Alignment) 모드 (mode)를 실현하고, 여기에 더하여 측면 시인성 문제까지 해결한 공정이 단순하며 높은 대비비를 구현하는 SPVA (Super Patterned Vertical Alignment) 및 PSVA (Polymer-Stabilized Vertical Alignment) 모드를 개발하였다. 이와 동시에 새로운 액정 주입 방식인 ODF (One Drop Filling) 기술을 최초로 양산에 접목함으로써 LCD 산업에서 경쟁사들이 따라올 수 없는 훨씬 앞선 제1 주자가 되었다. 이 보고서는 삼성이 SPVA와 PSVA 모드를 역경 속에서 타사들과 어떻게 경쟁하며 발전시켜 왔는가에 대한 내용과 ODF 기술에 대해 삼성의 고유 자산권을 침해하지 않는 범위 내에서 서술하고자 한다. ※ 대비비: 화면의 백색상태 (white state)와 암흑 상태 (black state)의 광비 (光比)