• 제목/요약/키워드: OC-1

검색결과 733건 처리시간 0.027초

Antiviral effects of Korean Red Ginseng on human coronavirus OC43

  • Chi Hwan Jeong;Jisu Kim;Bo Kyeong Kim;Kang Bin Dan;Hyeyoung Min
    • Journal of Ginseng Research
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    • 제47권2호
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    • pp.329-336
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    • 2023
  • Background: Panax ginseng Meyer is a medicinal plant well-known for its antiviral activities against various viruses, but its antiviral effect on coronavirus has not yet been studied thoroughly. The antiviral activity of Korean Red Ginseng (KRG) and ten ginsenosides against Human coronavirus OC43 (HCoV-OC43) was investigated in vitro. Methods: The antiviral response and mechanism of action of KRG extract and ginsenoside Rc, Re, Rf, Rg1, Rg2-20 (R) and -20 (S), Rg3-20 (R) and -20 (S), and Rh2-20 (R) and -20 (S), against the human coronavirus strain OC43 were investigated by using plaque assay, time of addition assay, real-time PCR, and FACS analysis. Results: Virus plaque formation was reduced in KRG extract-treated and HCoV-OC43-infected HCT-8 cells. KRG extract decreased the viral proteins (Nucleocapsid protein and Spike protein) and mRNA (N and M gene) expression, while increased the expression of interferon genes. Conclusion: KRG extract exhibits antiviral activity by enhancing the expression of interferons and can be used in treating infections caused by HCoV-OC43.

Ethyl Silicate의 가수분해에 의한 단분산 Silica 미립자의 합성(1) (Synthesis of Monodispersed Silica Fine Particle by Hydrolysis of Ethyl Silicate(1))

  • 오일환;박금철
    • 한국세라믹학회지
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    • 제24권5호
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    • pp.500-506
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    • 1987
  • In order to synthesize monodispersed spherical silica fine particles, we investigated the reaction of hydrolysis of 0.05∼4.0 mole Si(OC2H5)4-0.01∼7.60mole NH3 -0.24∼38.40 mole H2O-2.62∼16.88mole C2H5OH systems. The range of the composition of solution which spherical silica particles were formed was enlarged according to an increase in concentration of Si(OC2H5)4. Larger particles were obtained at higher molar ratios of Si(OC2H5)4/C2H5OH, NH3/H2O and H2O/Si(OC2H5)4 and at a lower reaction temperature.

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CH4 농도 변화가 저유전 SiOC(-H) 박막의 유전특성에 미치는 효과 (Effect of CH4 Concentration on the Dielectric Properties of SiOC(-H) Film Deposited by PECVD)

  • 신동희;김종훈;임대순;김찬배
    • 한국재료학회지
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    • 제19권2호
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    • pp.90-94
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    • 2009
  • The development of low-k materials is essential for modern semiconductor processes to reduce the cross-talk, signal delay and capacitance between multiple layers. The effect of the $CH_4$ concentration on the formation of SiOC(-H) films and their dielectric characteristics were investigated. SiOC(-H) thin films were deposited on Si(100)/$SiO_2$/Ti/Pt substrates by plasma-enhanced chemical vapor deposition (PECVD) with $SiH_4$, $CO_2$ and $CH_4$ gas mixtures. After the deposition, the SiOC(-H) thin films were annealed in an Ar atmosphere using rapid thermal annealing (RTA) for 30min. The electrical properties of the SiOC(-H) films were then measured using an impedance analyzer. The dielectric constant decreased as the $CH_4$ concentration of low-k SiOC(-H) thin film increased. The decrease in the dielectric constant was explained in terms of the decrease of the ionic polarization due to the increase of the relative carbon content. The spectrum via Fourier transform infrared (FT-IR) spectroscopy showed a variety of bonding configurations, including Si-O-Si, H-Si-O, Si-$(CH_3)_2$, Si-$CH_3$ and $CH_x$ in the absorbance mode over the range from 650 to $4000\;cm^{-1}$. The results showed that dielectric properties with different $CH_4$ concentrations are closely related to the (Si-$CH_3$)/[(Si-$CH_3$)+(Si-O)] ratio.

Organizational Climate Effects on the Relationship Between Emotional Labor and Turnover Intention in Korean Firefighters

  • Ryu, Hye-Yoon;Hyun, Dae-Sung;Jeung, Da-Yee;Kim, Chang-Soo;Chang, Sei-Jin
    • Safety and Health at Work
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    • 제11권4호
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    • pp.479-484
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    • 2020
  • Background: The purpose of this study is to examine the combined effects of organizational climate (OC) with emotional labor (EL) on turnover intention in Korean firefighters. Methods: The data were obtained from the study Firefighters Research: Enhancement of Safety and Health. A total of 4,860 firefighters whose main duty was providing "emergency medical aid" were included. To examine the effects of OC on the relationships between five subscales of EL and turnover intention, four groups were created using various combinations of OC ("good" vs. "bad") and EL ("normal" vs. "risk"): (1) "good" and "normal" (Group I), (2) "bad" and "normal" (Group II), (3) "good" and "risk" (Group III), and (4) "bad" and "risk" (Group IV). Multivariate logistic regression analyses were performed to estimate the risk of turnover intention for the combinations of OC and EL. Results: The results showed turnover intention was significantly higher in the group with "bad" OC (17.7%) than in that with "good" OC (7.6%). Combined effects of OC and EL on turnover intention were found in all five subscales with the exception of Group I for emotional demands and regulation. Groups II, III, and IV were more likely to experience risks of turnover intention than Group I (p for trend <0.001). Conclusions: A positive and cooperative OC plays a role in decreasing the risk of turnover intention and in attenuating the negative effects of EL on turnover intention in firefighters.

졸-겔법에 의한 $0.9Pb(Mg_{1/3}Nb_{2/3})O_{3}-0.1PbTiO_{3}$ 분말의 합성 ($0.9Pb(Mg_{1/3}Nb_{2/3})O_{3}-0.1PbTiO_{3}$ powder synthesis by sol-gel process)

  • 연석주;이진철
    • 한국결정성장학회지
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    • 제11권1호
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    • pp.27-32
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    • 2001
  • 본 연구에서는 금속 알콕시드를 이용하여 졸-겔법으로 0.9PMN-0.1PT 분말을 합성하는데 있어 과량으로 첨가되는 ${Mg(OC_{2}H_{5})}_2$${Pb(CH_{3}COO)}_2.3H_{2}O$ 등이 페로브스카이트 상의 생성량에 미치는 영향을 검토하였다. 그결과 합성된 겔을 열처리할 때 하소 온도가 증가함에 따라 페로브스카이트 상의 생성량은 증가하였으며 $850^{\circ}C$에서 4시간 유지하여 하소한 경우 페로브스카이트 생성량이 최대인 것으로 나타났다. 0.9PMN-0.1PT 조성에 ${Mg(OC_{2}H_{5})}_2$를 5 wt% 과잉 첨가한 합성 분말에서 페로브스카이트 단일상을 얻을 수 있었다.

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Mechanical stress가 골조직세포군에 미치는 영향 (THE EFFECTS OF MECHANICAL STRESS ON CULTURED BONE CELL POPULATIONS)

  • 김상태;차경석
    • 대한치과교정학회지
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    • 제24권1호
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    • pp.105-114
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    • 1994
  • The movement of teeth during orthodontic treatment requires bone remodeling process of bone formation and bone resolution. To find out the changes occuring in the cell itself, mechanical stress was applied to the cell populations involved in the bone metabolism. Bone tissue cell populations were isolated from fetal rat calvaria and divided into OC and OB groups. Following results were obtained from measuring the changes in acid & alkaline phosphatease activity, cyclic AMP and $PGE_2$ production in time lapse after the application of mechanical stress. 1. In case of the marker enzyme of specific bone tissue cell, acid phosphatase activity was high in OC group and alkaline phosphatase activity was high in OB group. 2. After the mechanical stress was applied, acid phosphatase activity was decreased in both OC and OB groups and alkaline phosphatase activity was increase in OB group. 3. When the mechanical stress was applied for 15, 30 and 60 minutes, the production of $PGE_2$ increased in both OC and OB groups, as the time span increased. 4. When the mechanical stress was applied for 20 and 40 minutes, the production of $PGE_2$ increased in both OC and OB groups, as the time span increased.

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가압 기포유동층에서 산소전달입자들의 환원반응특성 (Reduction Characteristics of Oxygen Carriers in a Pressurized Bubbling Fluidized Bed)

  • 윤주영;배달희;백점인;류호정
    • 한국수소및신에너지학회논문집
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    • 제27권5호
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    • pp.589-596
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    • 2016
  • Effects of pressure, temperature, gas velocity, and fuel flow rate on reduction of three oxygen carriers, SDN70, OC-1, OC-2, were measured and investigated in a pressurized bubbling fluidized bed reactor. Among three oxygen carriers OC-2 was selected as the best oxygen carrier in view of fuel conversion and $CO_2$ selectivity. However, all oxygen carriers showed good reactivity even at high pressure conditions. SDN70 particle showed maximum reactivity at $900^{\circ}C$ and low reactivity at $950^{\circ}C$. However, reactivity decay of OC-1 and OC-2 particles at high temperature condition was negligible. The fuel conversion and the $CO_2$ selectivity slightly decreased as the gas velocity increased, whereas they are slightly increased as the fuel concentration increased.

One-Class 서포트 벡터 머신을 이용한 레벨 셋 트리 생성 (Creating Level Set Trees Using One-Class Support Vector Machines)

  • 이계민
    • 정보과학회 논문지
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    • 제42권1호
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    • pp.86-92
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    • 2015
  • 레벨 셋 트리는 다차원에 정의된 확률 밀도 함수를 표현하는데 유용하다. 복잡한 데이터의 구조를 트리 형태로 시각화하여 데이터의 형태를 효율적으로 파악할 수 있으며 클러스터링 분석에 효과적으로 이용할 수 있다. 본 논문에서는 미지의 확률 밀도 함수에서 생성된 데이터 샘플로부터 레벨 셋 트리를 생성하는 알고리즘을 제안한다. 제안된 알고리즘은 레벨을 0에서부터 무한대로 증가시키며 밀도 함수의 각 레벨 셋을 추정하고, 이로부터 레벨 셋 트리를 생성한다. 이를 위해 본 논문에서는 one-class 서포트 벡터 머신 (OC-SVM)을 이용하여 직접적으로 레벨 셋을 추정한다. 이때 다양한 레벨 값에 대해 OC-SVM 학습을 반복해야 하는데, OC-SVM 솔루션 path 알고리즘을 통해 빠른 시간 안에 모든 레벨값에 해당하는 레벨 셋를 추정할 수 있다.

에틸실리케이트의 가수분해에 의한 실리카 미립자 생성반응의 속도론적 연구 (Reaction Kinetics in the Formation of Silica Fine Particles By the Hydrolysis of Ethyl Silicate)

  • 김한수;김희택;배성렬;유경옥
    • 한국결정성장학회지
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    • 제1권1호
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    • pp.92-99
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    • 1991
  • $Si(OC_2H_5)_4$ 로부터 $SiO_24$ 미립자를 얻는 반응은 가수분해반응과 종합반응의 두 단계로 이루어지며 중합반응은 $Si(OC_2H_5)_4$의 농도에 대하여 1차 반응이었다. 중합반응의 반응속도상수는 물의 농도와 촉매의 농도가 증가할수록 그리고 반응온도가 높아질수록 커지는 경향을 나타내고 있다. 생성된 실리카의 직경은 $0.06-0.27\mu\textrm{m}$이었으며 직경은 $Si(OC2H5)4$의 초기농도가 작아질수록 온도가 시간에 따라 입자가 성장해가는 속도는 전화율의 함수로 d=a.ln(Xa)+b 의 형태로 나타낼 수 있으며 최종 실리카의 직경은 사수 b값에 접근하였다.

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Effects of water temperature changes on oxygen consumption and hematological factors in olive flounder Paralichthys olivaceus

  • Lim, Han Kyu;Han, Hyon Sob;Hur, Jun Wook
    • Fisheries and Aquatic Sciences
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    • 제24권2호
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    • pp.99-107
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    • 2021
  • Water temperature (WT) is a major environmental factor of metabolic rate in fish; it directly affects food intake, ammonia excretion, oxygen consumption (OC), growth, and survival. Thus, the purpose of this study was to investigate changes in the OC and the hematological response of olive flounder Paralichthys olivaceus because of WT changes. In Exp. I, WT was increased from 20℃ to 29℃ within 18 h and maintained at 29℃ for 96 h. Then, WT was decreased from 29℃ to 20℃ within 18 h and maintained at 20℃ for 24 h. In Exp. II, WT was decreased from 20℃ to 11℃ within 18 h and maintained at 11℃ for 96 h. Then, WT was increased from 11℃ to 20℃ within 18 h and maintained at 20℃ for 24 h. The Exp. III maintained that the Exp. I and II was consecutively. In Exp. I, the OC increased from 116.7 mg O2 kg-1 hr-1 to 317.5 mg O2 kg-1 hr-1 with increasing WT. In Exp. II, the OC decreased from 96.5 mg O2 kg-1 hr-1 to 71.3 mg O2 kg-1 hr-1 with decreasing WT. In Exp. III, OC tended to increase or decrease in inverse proportion to temperature. In Exp. I, cortisol, glucose, and aspartate aminotransferase (AST) values increased with increasing WT. In Exp. II, Cl-, osmolality, AST, and alanine aminotransferase (ALT) values significantly changed during the experimental period: glucose values increased, whereas cortisol values decreased with decreasing WT. Exp. III was shown to be a more stressful environment to olive flounder than Exp. I and Exp. II. The results of our study will be useful for evaluating current aquaculture procedures of olive flounder and developing techniques to minimize stress in aquaculture farms.