• Weed & Turfgrass Science
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• v.5 no.4
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• pp.260-267
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• 2016

Amino acids in the plant were intermediate metabolites which produced by uptake and assimilation of nitrogen and these extracts which gained by bio-chemical digestion from protein of plant or animal were a source of functional fertilizer. This study was conducted to evaluate effects of keratin amino acid fertilizer (KAF) gained from animal hair or hoof on changes of turfgrass quality and growth by investigating turf color index, chlorophyll index, shoot number, clipping yield, and nutrient content in the turfgrass tissue. Treatments were designed as follows; non-fertilizer (NF), compound fertilizer (CF), keratin amino acid fertilizer treatments [CF + KAF $0.26ml\;m^{-2}$ (CKF), CF + KAF $0.52ml\;m^{-2}$ (2CKF)], and only keratin amino acid fertilizer treatment (KF). Shoot number, clipping yield, and nitrogen uptake of KF were higher than those of CF. As compared with CF, soil chemical properties, turf color index, chlorophyll index and clipping yield of keratin amino acid fertilizer were not significant, but shoot number and uptake of N and K were increased significantly. These results show that the application of keratin amino acid fertilizer increased shoot number and growth by increased uptake of nitrogen and potassium.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.4
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• pp.1082-1091
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• 2003

To elucidate the neuroprotective effect of Kamijihwang-hwan(KSH) on nerve cells damaged by hypoxia, the cytotoxic effects of exposure to hypoxia were determined by XTT, NR, MTT and SRB asssay. The activity of catalase and SOD was measured by spectrophometry, and TNF-α and PKC activity was measured after exposure to hypoxia and treatment of Kamijihwang-hwan(KSH) water extract(KJHWE). Also the neuroprotective effect of KJHWE was researched for the elucidation of neuroprotective mechanism. The results were as follows ; Hypoxia decreased cell viability measured by XTT, NR assay when cultured cerebral neurons were exposed to 95% N2/5% CO₂ for 2～26 minutes in these cultures and KJHWE inhibited the decrease of cell viability. H₂O₂ treatment decreased cell viability measured by MTT, and SRB assay when cultured cerebral neurons were exposed to 1-80 uM for 6 hours, but KJHWE inhibited the decrease of cell viability. Hypoxia decreased catalase and SOD activity, and also TNF-α and PKC activity in these cultured cerebral neurons, but KJHWE inhibited the decrease of the catalase and SOD activity in these cultures. Hypoxia triggered the apoptosis via caspase activation and internucleosomal DNA fragmentation. Also hypoxia stimulate the release of cytochrome c form mitochondria. KJHWE inhibited the apoptosis via caspase activation induced by hypoxia. From these results, it can be suggested that brain ischemia model induced hypoxia showed neurotoxity on cultured mouse cerebral neurons, and the KJHWE has the neuroprotective effect in blocking the neurotoxity induced by hypoxia in cultured mouse cerebral neurons.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.1
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• pp.18-26
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• 2015

Akebiae Caulis is a galenical originated from Akebia quinata Decaisne species. It is commonly used in the treatment of oposiuria, inflammation, nociceptive and fever. Here, we investigated the effect of Akebiae Caulis extract (ACE) to protect hepatocyte against the malfunction of mitochondria and apoptosis. Arachidonic acid (AA)+iron promoted excessive reactive oxygen species (ROS) production and exerted a deleterious effect on mitochondria. Treatment with ACE protected hepatocytes from AA+iron-induced cytotoxicity, as shown by alterations in the protein levels related with apoptosis such as poly(ADP-ribose) polymerase, pro-caspase 3, Bcl-XL and Bcl-2. Moreover, AA+iron-induced $H_2O_2$ production, GSH depletion and mitochondrial dysfunction were alleviated by ACE pretreatment. As a potential molecular mechanism for the ACE-mediated cytoprotection, phosphorylation of AMP-activated protein kinase (AMPK), a key regulator in determining cell survival or death, was increased by ACE. Moreover, ACE treatment enhanced inactive phosphorylation of glycogen synthase kinase-$3{\beta}$ ($GSK3{\beta}$), downstream substrate kinase of AMPK. More importantly, ACE prevented a decrease in the $GSK3{\beta}$ phosphorylation derived by AA+iron, which might contribute to mitohondiral protection and cell survival. To further identify essential compounds in Akebiae Caulis for the protection of AA+iron-mediated cytotoxicity, we found that betulin in combination with hederagenin protected from AA+iron-induced mitochondrial dysfunction. Betulin+hederagenin treatment also increased inactive phosphorylation of $GSK3{\beta}$ in common with ACE. These results suggest that ACE protected hepatocytes against oxidative stress and mitochondrial dysfunction, which is mediated with inactive $GSK3{\beta}$ phosphorylation downstream of AMPK.

• Economic and Environmental Geology
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• v.32 no.6
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• pp.611-631
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• 1999

Enviromental geochemisty and heary metal contamination at the Kongjueil mine creek were underaken on the basis of physicohemical properties and mineralogy for various kinds of water (surface, mine and ground water),soil, precipitate and sediment collected of April and December in 1998. Hydrgeochemical composition of the water samples are characterized by relatively significant enricant of Ca+Na, alkiali ions $NO_3$ and Cl inground and surfore water, wheras the mine waters are relatively eneripheral water of the mining creek have the characteristics of the (Ca+Mg)-$(HCO_3+SO_4)$type. The pH of the mine water is high acidity (3.24)and high EC (613$\mu$S/cm)compared with those of surface and ground water. The range of $\delta$D and $\delta^{18}O$ values (relative to SMOW) in the waters are shpwn in -50.2 to -61.6% and -7.0 to -8.6$\textperthousand$(d value=5.8 to 8.7). Using computer program, saturation index of albite, calcite, dolomite in mine water are nearly saturated. The gibbiste, kaolinite and smectite are superaturated in the surface and ground water, respectively. Calculated water-mineral reaction and stabilities suggest that weathing of silicate minerals may be stable kaolinite owing to the continuous water-rock reaction. Geochemical modeling showed that mostly toxic heavy metals may exist larfely in the from of metal-sulfate $(MSO_4\;^2)$and free metal $(M^{2+})$ in nmine water. These metals in the ground and surface water could be formed of $CO_3$ and OH complex ions. The average enrichment indices of water samples are 2.72 of the groundwater, 2.26 of the surface water and 14.15 of the acid mine water, normalizing by surface water composition at the non-mining creek, repectively. Characteristics of some major, minor and rate earth elements (Al/Na, K/Na, V/Ni, Cr/V, Ni/Co, La/Ce, Th/Yb, $La_N/Yb_N$, Co/Th, La/Sc and Sc/Th) in soil and sediment are revealed a narrow range and homogeneous compositions may be explained by acidic to intermediate igneous rocks. And these suggested that sediment source of host granitic gneiss colud be due to rocks of high grade metamorphism originated by sedimentary rocks. Maximum concentrations of environmentally toxic elements in sediment and soil are Fe=53.80 wt.% As=660, Cd=4, Cr=175, Cu=158, Mn=1010, Pb=2933, Sb=4 and Zn=3740 ppm, and extremely high concentrations are found are found in the subsurface soil near the ore dump and precipitates. Normalizing by composition of host granitic gneiss, the average enerichment indices are 3.72 of the sediments, 3.48 of the soils, 10.40 of the precipitates of acid mine drainage and 6.25 of the soils near the main adit. The level of enerichment was very severe in mining drainage sediments, while it was not so great in the soils. mineral composition of soil and sediment near the mining area were partly variable being composed of quartz, mica, feldspar, chlorite, vermiculite, bethierin and clay minerals. reddish variable being composed of quartz, mica, feldspar, chlorite, vermiculite, bethierin and clay minerals. Reddish brown precipitation mineral in the acid mine drainage identifies by schwertmanite. From the separated mineralgy, soil and sediment are composed of some pyrite, arsenopyite, chalcopyrite, sphalerite, galena, malachite, goethite and various kinds of hydroxied minerals.

• Journal of KIISE:Computer Systems and Theory
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• v.36 no.1
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• pp.26-32
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• 2009

The multi-level storage architecture has been widely adopted in servers and data centers. However, while prefetching has been shown as a crucial technique to exploit sequentiality in accesses common for such systems and hide the increasing relative cost of disk I/O, existing multi-level storage studies have focused mostly on cache replacement strategies. In this paper, we show that prefetching algorithms designed for single-level systems may have their limitations magnified when applied to multi-level systems. Overly conservative prefetching will not be able to effectively use the lower-level cache space, while overly aggressive prefetching will be compounded across levels and generate large amounts of wasted prefetch. We design and implement a hierarchy-aware lower-level prefetching strategy called PMS(Prefetching strategy for Multi-level Storage system) that applicable to any upper level prefetching algorithms. PMS does not require any application hints, a priori knowledge from the application or modification to the va interface. Instead, it monitors the upper-level access patterns as well as the lower-level cache status, and dynamically adjusts the aggressiveness of the lower-level prefetching activities. We evaluated the PMS through extensive simulation studies using a verified multi-level storage simulator, an accurate disk simulator, and access traces with different access patterns. Our results indicate that PMS dynamically controls aggressiveness of lower-level prefetching in reaction to multiple system and workload parameters, improving the overall system performance in all 32 test cases. Working with four well-known existing prefetching algorithms adopted in real systems, PMS obtains an improvement of up to 35% for the average request response time, with an average improvement of 16.56% over all cases.

• Geosciences Journal
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• v.23 no.1
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• pp.1-20
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• 2019

We present data from the Mesozoic Keumkang, Palbong, and Baekhwa granites in Garorim Bay, in the southwestern part of the Gyeonggi massif, South Korea. Using major and trace element concentrations, Sr-Nd-Pb isotopic compositions, and sensitive high-resolution ion microprobe (SHRIMP) zircon U-Pb ages, we aim to constrain the petrogenesis of the granites and explain their origin within a broader regional geological context. SHRIMP U-Pb zircon ages of $232.8{\pm}3.2$, $175.9{\pm}1.2$, and $176.8{\pm}9.8$ Ma were obtained from the Keumkang, Palbong and Baekhwa granites, respectively. The Late Triassic Keumkang granites belong to the shoshonite series and show an overall enrichment in large ion lithophile elements (LILE), a depletion in high field strength elements (HFSE) relative to primitive mantle, compared with neighboring elements in the primitive mantle-normalized incompatible trace element diagram with notable high Ba and Sr contents, and negligible Eu anomalies. The Keumkang granites are typified by highly radiogenic Sr and unradiogenic Nd and Pb isotopic compositions: $(^{87}Sr/^{86}Sr)_i=0.70931-0.70959$, $(^{143}Nd/^{144}Nd)_i=0.511472-0.511484$ [$({\varepsilon}_{Nd})_i=-17.0$ to -16.7], and $(^{206}Pb/^{204}Pb)=17.26-17.27$. The Middle Jurassic Palbong and Baekhwa granites belong to the medium- to high-K calc-alkaline series, and show LILE enrichment and HFSE depletion similar to the Keumkang granites, but exhibit significant negative anomalies in Ba, Sr, and Eu. Furthermore, they have elevated Y and Yb contents at any given $SiO_2$ content compared with other Jurassic granitoids from the Gyeonggi massif. The Palbong and Baekhwa granites have slightly less radiogenic Sr and more radiogenic Nd and Pb isotopic compositions [$(^{87}Sr/^{86}Sr)_i=0.70396-0.70908$, $(^{143}Nd/^{144}Nd)_i=0.511622-0.511660$, $({\varepsilon}_{Nd})_i=-15.4$ to -14.7, $(^{206}Pb/^{204}Pb)=17.56-17.76$] relative to the Keumkang granites. The Keumkang granites are considered to have formed in a post-collisional environment following the Permo-Triassic Songrim orogeny that records continent-continent collision between the North and South China blocks, and may have formed by fractional crystallization of metasomatized lithospheric mantle-derived mafic melts. The Palbong and Baekhwa granites may have been produced from a gabbroic assemblage at pressures of less than ~15 kbar, associated with subduction of the paleo-Pacific (Izanagi) plate at the Eurasian continental margin. Elevated ${\varepsilon}_{Nd}(t)$ values in the granitoids from the southwestern part of the Gyeonggi massif relative to those of the central and northern parts, together with the comparatively shallow depth of origin, imply the presence of an exotic block in the Korean lithosphere.

• Journal of Korean Philosophical Society
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• v.123
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• pp.1-26
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• 2012

Ist der Emotivismus eine $mi{\ss}lungene$ Theorie? Nach der Meinung von Jesse Prinz ist es nicht so. Auf der Humeschen Tradition stehend behauptet er, $da{\ss}$ ein moralisches Urteil ohne das Sentiment von Billigung oder $Mi{\ss}billigung$ nicht zustandekommen kann. Ihm zufolge ist Emotion nicht allein mit moralischen Urteilen verbunden, sondern auch eine notwendige und hinreichende Bedingung $daf{\ddot{u}}r$. Der Grund dessen, warum der Emotivisums nicht ${\ddot{u}}berzeugend$ erschien, liegt darin, $da{\ss}$ $f{\ddot{u}}r$ diesen die Verbindung von Emotion und Moral nur auf den $Gef{\ddot{u}}hlsausdruck$ $beschr{\ddot{a}}nkt$ bleibt. Zwar stellt das moralische Urteil Sentiment dar, aber das bleibt eben nicht als ein $blo{\ss}$ $Gef{\ddot{u}}hlsausdruckendes$. Denn die $Moralit{\ddot{a}}t$ ist nicht die einfache Projektion eines subjektiven Zustandes, vielmehr konstruiert die emotionale Reaktion von Billigung oder $Mi{\ss}billigung$ das moralische Urteil. Daher muss der projektistische Gesichtspunkt des expressionistischen Emotivismus modifiziert werden, so $da{\ss}$ der oft dem Emotivismus kritisch zugeschriebene moralische Nihilismus zu ${\ddot{u}}berwinden$ ist. In diesem Zusammenhang $schl{\ddot{a}}g$ Prinz den konstruktiven Sentimentalismus vor, der als eine hybride Theorie des Moralbegriffs von 'biologiscehn Tatsachen' und 'sozialer Konstruktion' darauf zielt, im moralischen Leben eine Stelle auszumanchen, wo Evolution und Kutur zueinander zusammentreffen $k{\ddot{o}}nnen$.

• Resources Recycling
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• v.28 no.5
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• pp.51-59
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• 2019

This study focused on the synthesis of the nickel hydroxide using ammonium sulfate in leaching solution from waste nickel-cadmium batteries. The effect of pH, temperature and the input amount of ammonium sulfate in leaching solution was investigated. The ammonium nickel sulfate with high purity was obtained in acidic leaching solution and the solution temperature of $60^{\circ}C$. The suitable molar ratio of the input amount of ammonium sulfate to nickel in solution is 2:1. The impurity about 1.4 at.% of Cd was included in the nickel hydroxide precipitates when ammonium nickel sulfate was used. At the process using sodium sulfide which precipitates the cadmium in solution, nickel and iron compounds were precipitated together.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.69-69
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• 2019

해당화 열매를 숙기 별로 과육의 항산화물질 함량과 씨앗의 지방산 함량을 측정하여 평가하였다. 과육의 1,1-diphenyl-2-picrylhydrazyl (DPPH) 항산화능을 갈산 환산농도로 나타내면 미성숙 과육은 $4.36{\pm}0.03mg/g$, 성숙 초기 과육은 $4.54{\pm}0.37mg/g$, 성숙 중기 과육에는 $4.78{\pm}0.21mg/g$, 성숙 후기에는 $4.30{\pm}0.22mg/g$ 범위로 항산화능을 보여주었다. 항산화능력은 성숙중기에서 높은 함량을 보여주었고 성숙함에 따라 감소함을 보여주었다. 미성숙, 성숙 초기는 유의한 걸로 나오지만 성숙 중기와 성숙 후기은 다른 성숙도와 유의하지 않았다. 총 페놀 함량의 미성숙 과육은 $1.60{\pm}0.03mg/g$, 성숙 초기 과육은 $1.80{\pm}0.08mg/g$, 성숙 중기 과육에는 $2.03{\pm}0.67mg/g$, 성숙 후기에는 $1.53{\pm}0.07mg/g$ 범위로 폴리페놀이 존재하였다. 성숙 초기에 제일 높은 항산화능력과 폴리페놀 함량을 보여주고 있으며 성숙할수록 항산화능력과 총 페놀 함량이 떨어지는 것을 알 수 있다. 씨앗의 지방산 함량은 리올레산, 리놀렌산, 올레산, 팔미트산 순으로 많았다. 리올레산은 미성숙 씨앗은 전체 함량 중 56.46%, 초기 과육 씨앗에는 54.26%, 중기 과육 씨앗에는 51.67%, 후기 씨앗에는 50.75%의 함량을 가지고 있다. 리올렌산은 미성숙 씨앗은 전체 함량 중 18.80, 초기 과육 씨앗에는 17.96%, 중기 과육 씨앗에는 18.90%, 후기 씨앗에는 21.42%의 함량을 가지고 있다. 올레산은 미성숙 씨앗은 전체 함량 중 13.54%, 초기 과육 씨앗에는 20.78%, 중기 과육 씨앗에는 22.44%, 후기 씨앗에는 20.81%의 함량을 가지고 있다. 팔미트산은 미성숙 씨앗은 전체 함량 중 6.80%, 초기 과육 씨앗에는 3.40%, 중기 과육 씨앗에는 3.37%, 후기 씨앗에는 3.32%의 함량을 가지고 있다. 리올레산은 미성숙 시기에 가장 많았고 리올렌산은 후기에 올레산은 중기에, 팔미트산은 초기에 많았다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.17-17
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• 2019

진퍼리사초는 한반도 중부 이북에 분포하고, 군락 자생지는 강원도 동해안 석호 주변 모래땅 1곳인 것으로 보고되고 있다. 따라서 본 연구는 진퍼리사초 현지외보전을 위한 대량증식 연구의 일환으로 가장 효과적인 파종 시기를 구명하고자 수행하였다. 종자의 최적 발아조건을 찾기 위해 배양상 온도조건을 항온(30, 25, 20, 15, $5^{\circ}C$)과 변온(15/30, 20/10, $25/15^{\circ}C$) 총 8가지 조건으로 설정하여 발아율을 매일 측정하였다. 광조건은 명/암을 매일 12시간씩 반복하였으며 모든 실험은 국립백두대간수목원 발아실험실의 생장상에서 진행하였다. 실험결과, 항온조건에서 발아율은 $30^{\circ}C$에서 $39{\pm}7.5%$로 가장 높게 나타났고, $20^{\circ}C$ ($28{\pm}4.3%$), $25^{\circ}C$ ($24{\pm}3.7%$) 순으로 나타났으며, $15^{\circ}C$, $5^{\circ}C$에서는 발아하지 않았다. 한편, 변온조건에서의 발아율은 $25/15^{\circ}C$에서 $60{\pm}5.9%$로 가장 높게 나타났고, $15/30^{\circ}C$ ($43{\pm}4.1%$), $20/10^{\circ}C$ ($26{\pm}3.8%$) 순으로 나타났다. 따라서 진퍼리사초의 종자 발아는 항온보다 변온에서 잘 이루어졌으며, $25^{\circ}C$이상의 온도가 효과적인 것으로 나타났다. 이러한 결과를 바탕으로 가장 효과적인 파종 시기를 추정할 때, 낮 기온이 평균 $25^{\circ}C$이상이며, 일교차가 $10^{\circ}C$ 정도인 초여름이 가장 적절할 것으로 여겨진다.