• Journal of Nutrition and Health
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• 제51권3호
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• pp.215-227
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• 2018

본 연구는 심혈관질환으로 심장수술을 받은 환자 15명 대상에게서 12주 동안 한식으로 식이조절 교육을 통해 한식 섭취가 증가하고 이를 통해 CVD 위험인자 및 약물 투여량의 변화, 영양소 섭취량에 미치는 영향과 관련성에 대한 분석 결과는 다음과 같았다. 1. 대상자의 평균 연령은 $60.7{\pm}2.5$세로 최근 3년 이내에 심혈관질환 수술을 받고 지속적으로 심혈관질환 약물을 복용하고 있는 환자였다. 2. 대상자의 한식 식이조절 교육 순응도 점수는 교육 전 $35.8{\pm}0.9$점에서 교육 후 $43.0{\pm}1.2$점으로 유의적으로 증가하였는데 (p < 0.001), 이는 한식 섭취를 적극적으로 실천하였음을 시사한다. 3. 대상자의 비만지표인 체중 및 체질량지수는 교육 후, 감소 경향을 보였으며 허리둘레 (p = 0.002) 및 허리 엉덩이둘레비인 WHR (p < 0.001)는 유의적으로 감소하였다. 4. 대상자들의 혈당조절 지표인 HbA1c는 교육 전 $7.3{\pm}1.0%$에서 교육 후 $7.0{\pm}1.1%$로 유의적으로 감소하였다 (p < 0.05). 5. 대상자들의 항고혈압제약물의 투여량 변화는 교육 전 2.1개에서 교육 후 1.7개로 줄었음에도 불구하고 혈압은 정상범위에서 안정적으로 유지되었음을 확인하였다. 항당뇨병 약제 복용량은 유의적인 변화는 보이지 않았으나, 안정된 상태로 적절한 혈당을 유지함과 동시에 혈당 조절 지표인 당화혈색소가 감소함을 확인하였는데 이는 혈당조절이 개선되고 있는 것으로 나타났다. 6. 한식 식사유형인 음식군별 섭취량의 변화는 교육 전에 비해 교육동안에 전곡류로 지은 밥 중심의 식사량이 유의적으로 증가하였고 (p = 0.018), 채소류인 나물류 (p = 0.007), 김치 (p < 0.001) 및 전통 콩발효 양념 (p < 0.001) 등의 섭취가 유의적으로 증가하였다. 7. 대상자들의 영양소 섭취는 일일 에너지 섭취량은 변화가 없었으나 교육 전보다 교육 동안에 동물성급원식품에서 유래한 동물성 단백질과 지질 및 콜레스테롤의 섭취량은 유의적으로 감소 (p < 0.05)한 반면 나트륨 (p = 0.019), 칼륨 (p = 0.028), 식이섬유 (p < 0.050), 비타민 A (p = 0.028), 비타민 C (p = 0.010) 및 엽산 (p < 0.001)의 섭취는 유의적으로 증가하였다. 이상의 결과를 종합해 보면, 적극적인 한식 섭취를 권장하고 장려하는 식이조절교육 중재는 심혈관질환 수술을 받은 환자에게서 영양소 섭취와 심혈관계 위험인자인 비만지표, 혈당조절 지표에 대하여 긍정적인 영향을 주었다. 본 연구의 한계로는 교육에 참여한 대상자가 15명으로 다소 적었으며 단기 교육에 의한 전후 비교 평가에 의한 것으로 그 결과를 일반화하기에는 제한점이 있다. 따라서 향후 연구 장기간의 교육과 대조군이 있는 비교 연구가 필요할 것으로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3997-4002
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• 2015

Background: Systemic inflammatory response was shown to play an important role in development and progression of many cancer types and different inflammation-based indices were used for determining prognosis. We aimed to investigate the prognostic effects of neutrophil to lymphocyte ratio (NLR) and prognostic nutritional index (PNI) in patients with non-small cell lung cancer (NSCLC). Materials and Methods: NSCLC patients diagnosed in our institution were retrospectively reviewed. Demographic and clinicopathologic characteristics were recorded. NLR and PNI was calculated before the application of any treatment. Results: A total of 138 patients were included in the study. Patients were divided into two groups according to NLR (<3.24 or ${\geq}3.24$) and PNI (<49.5 or ${\geq}49.5$). While median overall survival was 37.0 (95% CI 17.5-56.5) months in the group with low NLR, it was calculated as 10.0 (95%CI 5.0-15.0) months in the group with high NLR (p<0.0001). While median overall survival was 7.0 (95%CI 3.5-10.5) months in the group with low PNI, it was calculated as 33.0 (95% CI 15.5-50.4) months in the group with high PNI (p<0.0001). Stage, NLR and PNI levels were evaluated as independent risk factors for overall survival for all patients in multivariate analysis (p<0.0001, p=0.04 and p<0.001, respectively). Conclusions: NLR (${\geq}3.24$) and PNI (<49.5) at diagnosis is an independent marker of poor outcome in patients with NSCLC. NLR and PNI is an easily measured, reproducible prognostic tests that could be considered in NSCLC patients.

• Journal of Korean Biological Nursing Science
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• 제12권1호
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• pp.39-47
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• 2010

Purpose: The purpose of this study was to investigate the health status, nutritional status, and nutrient intakes of Korean female elderly who are members of a local church in Seoul, Korea. Methods: The subjects were 59 female who are aged >65 yr. We investigated the nutritional status of the subjects using anthropometric and biochemical measurements. Interview was conducted to obtain the information regarding the health status. We also obtained dietary intake of these subjects to figure out the nutrient intakes. Results: The mean age of the subject was 74.0 yr old. Based on the WHO standard (obesity, body mass index, BMI ${\qeq}25$), we categorized the subjects to the obese and the non obese groups. The number of subjects in the obese group was 34 (57.6%). The mean Diastolic BP (p=.002), BMI (p<.001), waist circumference (p<.001), hip circumference (p<.001), blood level of transferrin (p=.038), and nutrient intakes of calcium (p=.026), potassium (p=.046), folate (p=.038) and vitamin E (p=.031) were higher in the obese group than in the non obese group. The subjects with hypertension was 67.5%. The presence of hypertension was correlated with BMI (p<.05). The number of subjects with hypercholesterolemia was 17 (28.8%). The level of cholesterol was correlated with BMI (p<.05) and wasit/hip ratio (p<.05). Conclusion: The female elderly in our study had higher prevalence of obesity which is a risk factor for hypertension and hypercholesterolemia. The nutrient intake of high sodium, high cholesterol, and low dietary fiber of these subjects suggests that there is an urgent need to develop an well planned nutritional education program for female elderly.

• Journal of Nutrition and Health
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• 제40권2호
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• pp.162-171
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• 2007

Obesity is an independent risk factor fur coronary artery disease in the postmenopausal women, which may be mediated by alteration of blood lipid metabolism. We are aimed to evaluate the effects of low energy diet, restriction of high fat foods and exercise education on weight, fat mass and blood lipid profile. Fifteen postmenopausal obese women were studied. Subjects received detailed advice about how to achieve a reduction of weight by a low-energy diet (1,200kcal), restriction of high fat food and increased exercise in every 4 wks during 8 wk. To evaluate the effectiveness for education programs, dietary fat habit and daily nutrient intakes, exercise were tested before and after intervention. Anthropometry, computerized tomography, and blood lipid profile were assessed before and after intervention. According to the nutrition education, energy intake (from 1776.1 ${\pm}$ 28.2 kcal to 1268.7 ${\pm}$ 115.2 kcal, p < 0.001) and percent of energy from fat (21.9%, p < 0.01) were significantly decreased. However, the index of nutritional quality was over 1.0. On the contrary, exercise (from 341.3 ${\pm}$ 222.1 kcal to 569.4 ${\pm}$ 309.8 kcal, p < 0.05) was increased and dietary fat habit scores (from 30.8 ${\pm}$ 5.2 to 36.1 ${\pm}$ 3.0, p < 0.01) were improved. Also, body weight (4.2%, p < 0.001), BMI (4.5%, p < 0.001), body fat mass (3.4%, p < 0.05) and waist to hip ratio (1.1%, p < 0.05) were decreased. Among abdominal fat, visceral fat (26.1%, p < 0.05) and subcutaneous fat (14.8%, p < 0.01) were decreased. But there was no difference in visceral fat to subcutaneous fat ratio. We observed HDL-cholesterol increase (11.7%, p < 0.05), triglyceride reduction(14.8%, p < 0.05) and atherogenic index improvement (from 2.7 ${\pm}$ 0.7 to 2.3 ${\pm}$ 0.7, p < 0.05) However, there was no change in LDL-cholesterol and total cholesterol. Theses results showed that low energy diet, restriction of high fat foods and exercise education could result in reduction of body weight, fat mass, visceral and subcutaneous fat, and in improvement of blood lipid profile in the postmenopausal obese women.

• 대한지역사회영양학회지
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• 제12권6호
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• pp.752-760
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• 2007

Inadequate nutritional status of pregnancy can cause underweight and premature birth, undergrowth and deliverance of physically and mentally defected babyies. The purpose of this study is to provide guidelines for preventing preterm delivery in the aspect of nutritional factors. The nutrient intakes were compared between a preterm delivery group and a normal term delivery group to recognize risk factors of preterm delivery. The results obtained are summarized as follows. The pregnancy period was statistically longer in the normal term group (p<0.0001). Weight increase was statistically higher in the normal term group (p<0.0001). Calories (p<0.05), carbohydrates (p<0.0005), dietary fibers (p<0.0001), potassium (p<0.0005), vitamin $B_1$ (p<0.0005), vitamin $B_6$ (p<0.05), vitamin C (p<0.0001), and folic acid (p<0.05) intakes were statistically higher in the normal term group. Nutrient density of vitamin $B_1$ (p<0.05) and vitamin C (p<0.0001) in the normal term group was statistically higher. Nutrient adequacy ratio of zinc (p<0.05), vitamin $B_1$ (p<0.05) and folic acid (p<0.05) were statistically higher in the normal term group. Index of Nutritional Quality of vitamin $B_1$ (p<0.05) and vitamin C (p<0.0001) were statistically higher in the normal term group. In this study, the normal term delivery showed higher intakes of calories, carbohydrates, dietary fiber, crude fiber, potassium, vitamin $B_1$, vitamin $B_6$ vitamin C and folic acid than the preterm delivery group. Deficiencies in various nutrients may lead to preterm delivery, therefore, balanced nutrient intake is recommended to prevent preterm delivery.

• 동아시아식생활학회지
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• 제25권1호
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• pp.39-48
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• 2015

This study aimed to compare and evaluate nutritive conditions of the female elderly (2,893 people) based on a national health nutrition survey and health-related factors influencing nutritional intake. The results are as follows.- Average age of all subjects was $72.12{\pm}5.2$ old. BMI ($24.48{\pm}3.3kg/m^2$) and waist size ($83.9{\pm}9.5cm$) of urban elderly was larger ($23.74{\pm}3.3kg/m^2$, $82.28{\pm}9.9cm$) than that of rural elderly. MAR[4] and MAR[10] were also higher in urban elderly than rural elderly. The results of multiple regression analysis showed that factors influencing poor nutrition of elderly subjects were increasing age, smoking, and self-rated health. Old-old and current smokers were associated with a higher likelihood of poor nutrition (OR 1.82, 95%CI 1.43~2.30) and (OR 3.40, 95%CI 2.17~5.33) elderly female subjects in urban areas. Smoking (OR 2.29, 95%CI 1.33~3.95), poor self-rated health (OR 1.55, 95%CI 1.11~2.16), over nine hours of sleep per nighting (OR 1.72, 95%CI 1.17~2.53) and stress (OR 1.46, 95%CI 1.10~1.92) of elderly female subjects in rural areas were associated with higher likelihood of a poor nutrition. In conclusion, rural elderly are more influenced by poor health practice behaviors (self-rated health, sleeping stress) and psychological factors. Nutrition status of the rural elderly is worse than that of the urban elderly. To reduce nutritional risk of Korean elderly, especially rural elderly, active nutrition arbitration should include psychological environmental factors.

• Nutrition Research and Practice
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• 제13권1호
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• pp.41-46
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• 2019

BACKGROUND/OBJECTIVES: Taste perception is influenced by both nutritional factors and psychological factors. This study was undertaken to measure the 4 basic taste perceptions, nutrient intake, and mental health, and to examine the factors that affect insensitive taste perception in young Japanese women. SUBJECTS/METHODS: Young women in their late teens and twenties were enrolled as subjects. Taste perception was measured by applying the filter-paper disc method over areas of the chorda tympani nerve. Nutritional status was evaluated using brief, self-administered diet history questionnaires. The index of nutritional status was based on the 2015 Japanese dietary reference intakes. Mental health was assessed using the Japanese translation of the Profile of Mood States short version. This study was approved by the ethical committee at Osaka University. RESULTS: The normal taste perception group (four basic tastes [sweet, salty, sour, and bitter] identified as normal taste perception) comprised 55.4% of the subjects, while the abnormal taste perception group (more than 1 abnormal taste perception was perceived, regardless of flavor) comprised 44.6% of the subjects. There were no significant differences in nutrient intake (except manganese) and mental health between the normal and abnormal taste perception groups. Subjects who took 5 mg to less than 7.1 mg zinc per day were at significantly decreased risk of insensitive taste perception compared to subjects who consumed less than 5 mg zinc per day [Regression coefficient 0.831, 95% confidence interval 0.694-0.996]. CONCLUSION: The present results suggest that insensitive taste perception could be associated with zinc deficiency in young women in their late teens and twenties.

• 대한지역사회영양학회지
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• 제25권6호
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• pp.502-511
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• 2020

Objectives: This study investigated the health and nutritional status of the elderly according to the number of chronic diseases, using data obtained from the Korea National Health and Nutrition Examination Survey 2013~2015. Methods: Data from a total of 2,310 individuals, aged 65 years and over, were used for the analysis. The elders were divided into 0 (n=375), 1 (n=673), 2 (n=637) and 3 or more (n=625) groups, by considering the number of chronic diseases. Results: Compared to other groups, the elderly subjects who were living with their spouse had the highest ratio in group 0 (P < 0.05), whereas subjects without economic activities had highest ratio in 3 or more group (P < 0.05). The EQ-5D index of subjects in the 0 group (0.90 ± 0.01) was higher than that in the 3 or more group (0.86 ± 0.01) (P < 0.05). After adjusting for confounding factors, the energy intake of subjects was determined to be lowest in the 3 or more group (P < 0.05). Protein (P < 0.05) and riboflavin (P < 0.05) intakes of the 3 or more group were also lower than other groups. Conclusions: This study indicates that multimorbidity of the elderly is associated with their health and nutritional status. The nutrients intake of the elderly, especially energy, protein and riboflavin, tended to be lowest in the 3 or more group. Further research is required to elucidate the risk factors related to presence of multimorbidity in the elderly.

• Journal of Nutrition and Health
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• 제27권10호
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• pp.1058-1069
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• 1994

This study was performed to study the effects of dietary factors on breast and cervical cancer incidence in female Koreans. The subjects were 60 breast and 109 cervical cancer patients recruited from five general hospitals in Seoul. Food intake, anthropometric measurement, and blood compositions were studied through personal interview and using medical records, from August 1991 to September 1992. Body weight, body mass index, triceps skinfold thickness and body muscle mass were at upper limit of normal value, which suggest that these patients had a tendency of overweight. The levels of hemoglobin and hematocrit of the patients were below the normal values. The values of serum protein, albumin, and calcium were in the normal range but close to the lower bound. Therefore the nutritional status assessed by blood composition seems to be marginal. The results of diet history showed that most of the nutrient intake of the subjects met with RDA. The fat intake were 22.9-36.9g/day which supplies about 15-16% of total calories. The results of this study do not agree with those reports of western societies which showed the positive correlation between calorie and fat intake and the incidence of breast and cervical cancer. Even through the calories and fat intake of the subjects were not high, it was higher than national average, especially in breast cancer patients. From this study, dietary factors does not seem to be a major risk factor in cancer incidence in Korea. However, the tendency of the increasing consumption of fat could be a contributing risk factor together with overweight.

• Journal of Trauma and Injury
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• 제35권4호
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• pp.255-260
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• 2022

Purpose: To determine the incidence and risk factors of postoperative infection after cranioplasty in patients with traumatic brain injury (TBI). Methods: Data of 289 adult patients who underwent cranioplasty after TBI at a single regional trauma center between year 2018 and 2021 were reviewed retrospectively. Patient characteristics and various procedural variables, such as interval between craniectomy and cranioplasty, estimated blood loss, laterality and materials of the bone flap, and duration and classification of perioperative antibiotics usage were analyzed. Results: Postoperative infection occurred in 17 patients (5.9%). Onset time of infectious symptom ranged from 9 days to 174 days (median, 24 days) after cranioplasty. The most common cultured organism was Staphylococcus aureus (47.1%), followed by Klebsiella pneumoniae (17.6%) and Enterococcus faecalis (17.6%). Patients with postoperative infection were more likely to have diabetes (odds ratio [OR], 6.96; 95% confidence interval [CI], 1.92-25.21; P=0.003), lower body mass index (OR, 0.81; 95% CI, 0.66-0.98; P=0.029), and shorter duration of perioperative antibiotics (OR, 0.83; 95% CI, 0.71-0.98; P=0.026). Conclusions: For TBI patients with diabetes, poor nutritional status should be managed cautiously for increased risk of infection after cranioplasty. Further studies and discussions are needed to determine an appropriate antibiotics protocol in cranioplasty.