• Korean Journal of Food Science and Technology
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• v.33 no.2
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• pp.252-255
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• 2001

This study was performed to investigate the influence of dietary mulberry leaf on the intestinal microflora in rats. Rats were fed each experimental diets containing 1%, 10% of mulberry leaf powder for 4 weeks. Total viable counts and the numbers of Bifidobacterium, Lactobacillus, Clostridium, E. coli and Staphylococcus were determined by nonselective media and various selective media. A decrease in the intestinal population of Clostridium was shown in dietary mulberry leaf group. The E. coli and Staphylococcus populations decreased in dietary mulberry leaf group compared with control group. Methanol extract and fractions of mulberry leaf were subjected to an in vitro screening test for their growth-inhibitory activity. Methanol extract and Water fraction of Mulberry leaves showed weak growth-inhibition of Clostridium perfringens. These results indicate that the composition of gastrointestinal microflora was improved by treatment of mulberry leaves in SD rats and was very effective for growth inhibition of the intestinal harmful bacteria in intestine. Therefore, the mulberry leaves as a newly bio-material can be a useful material for physiologically functional food.

• Journal of the Korean Data and Information Science Society
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• v.26 no.6
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• pp.1453-1463
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• 2015

The purpose of this study was to identify health behaviors of elderly with osteoarthritis across gender groups. Total of 1,654 age 65 over from the fifth Korean National health and Nutrition Examination Survey (KNHANES) were selected. The data analysis was performed using the complex sampling function of SPSS version 20. Logistic regression analysis shows the difference of risk factors of osteoarthritis between men and women elderly people. Prevalence of osteoarthritis in men elderly was associated with drinking, education for osteoarthritis, and treatment of osteoarthritis whereas the factors in woman elderly were depression and muscle strengthen exercise. Most of the subjects had not the opportunity of education of the management of the osteoarthritis. These findings from the study are expected to promote the screening strategy for the aged at risk of osteoarthritis in the Korean community and enhance the effect of the nursing intervention for the elderly with osteoarthritis.

• Korean Journal of Food Science and Technology
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• v.35 no.4
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• pp.680-683
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• 2003

Through the screening of caspase-3 inducing inhibitors in U937 human monocytic leukemia cell from natural sources, Caesalpiniae sappan, which showed a high level of inhibition, was selected. The inhibition compound was purified from methanol extract by silica gel column chromatography and HPLC. The inhibitor was identified as brazilin by spectroscopic methods of ESI-MS, $^1H-NMR$, and $^{13}C-NMR$. Brazilin showed inhibitory activity of caspase-3 induction, a major protease of apoptosis cascade, with $IC_{50}$ value of $4.5\;{\mu}g/mL$ after 7 hr of treatment in U937 cells.

• Korean Journal of Pharmacognosy
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• v.45 no.3
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• pp.227-232
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• 2014

The seed of Vigna angularis (Ohwi) Ohwi & Ohashi (= Phaseolus angularis W. F. Wight, Leguminosae) is one of well-known folk foodstuffs in Korea, China and Japan. In the course of screening for antioxidants from natural plants in Korea by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) a methanol extract of the seeds of V. angularis were found to show a potent antioxidant activity. And the ethyl acetate soluble fraction of V. angularis (VAEA) showed the most potent DPPH radical scavenging and superoxide quenching activities. To reveal the effect of antioxidant activities of VAEA, we tested the thermal and oxidative stress tolerances, activities of SOD and catalase, and intracellular ROS level in Caenorhabditis elegans. Consequently, VAEA-fed worms lived longer than control worms under the thermal and oxidative stress conditions. And VAEA elevated SOD and catalase activities of worms, and reduced intracellular ROS accumulation in a dose-dependent manner.

• The Korean Journal of Health Service Management
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• v.5 no.2
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• pp.77-89
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• 2011

This study conducted a secondary analysis by using original data of performed by Korea Institute for Health and Social Affairs to know factors affecting determinants of health using Lalonde model for the adults aged over 19 years living in Korea. The survey was conducted in 2009 and it evaluated finally 5,867 cases by excluding cases with no answer or a wrong answer. This study model adopted two categories of instrument measure health were objective (Average remaining lifetime) and subjective(EQ-5D) health status. The health determinants included in this study could be divided in to four categories, which were human biology, environment, lifestyle, and health care organization. The results were as follows. In the factors affecting average remaining lifetime, human biology were sex, ages, BMI, showed statistically significant difference, environment category were merry status, education showed statistically significant difference, lifestyle category were exercise, drunks showed statistically significant difference and health care organization category were vaccination, health screening showed statistically significant difference. In the factors affecting EQ-5D, human biology category and health care organization category showed with same average remaining lifetime, environment category were merry status, education, income showed statistically significant difference and lifestyle category were exercise, drunks, stress showed statistically significant difference. The results demonstrated that the best powerful factor was life style category and environment category, the least factor was health care organization category. So lifestyle style and environment category should be considered for the future health plan, budget allocation and the priority in the health care.

• Korean Journal of Food Science and Technology
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• v.34 no.6
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• pp.1002-1006
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• 2002

Germination method was used to screen the biological changes in soybean, kidney bean, and red bean caused by gamma irradiation. Beans were irradiated at 0.1, 0.3, 0.5, 0.7, and 1.0 kGy. Ten beans of each sample were placed on moistened cotton and germinated at $30{\circ}C$. The root lengths were measured daily for 5 days. Root lengths of all beans grew continuously for 5 days, but the growth rate of irradiated beans decreased significantly from fourth day. Unirradiated beans showed the highest growth rate during 5 days of germination. Gamma-irradiated beans could be screened by measuring the daily growth rate and root length during germination.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.413-420
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• 2019

The purpose of the present study is to develop a model for predicting hypercholesterolemia using an integrated set of body fat mass variables based on machine learning techniques, beyond the study of the association between body fat mass and hypercholesterolemia. For this study, a total of six models were created using two variable subset selection methods and machine learning algorithms based on the Korea National Health and Nutrition Examination Survey (KNHANES) data. Among the various body fat mass variables, we found that trunk fat mass was the best variable for predicting hypercholesterolemia. Furthermore, we obtained the area under the receiver operating characteristic curve value of 0.739 and the Matthews correlation coefficient value of 0.36 in the model using the correlation-based feature subset selection and naive Bayes algorithm. Our findings are expected to be used as important information in the field of disease prediction in large-scale screening and public health research.

• Korean Journal of Family Medicine
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• v.39 no.6
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• pp.340-346
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• 2018

Background: Several studies have revealed the frequency of family mealtimes to be inversely associated with depressive symptoms in adolescents. However, there have been few studies in older populations. This cross-sectional study investigated the association between family mealtime frequency and depressive symptoms in elderly Koreans. Methods: This study analyzed 4,959 elderly men and women (aged 65 years or older) who participated in the Korea National Health and Nutrition Examination Survey. Self-administered questionnaires were used to assess depressive status, family mealtime frequency, and covariates. Multiple logistic regression analysis was performed to evaluate the association using the eating alone group as a reference. Results: After adjusting for all covariates, participants who had family meals 3 times a day had fewer depressive symptoms than the eating alone group; adjusted odds ratios (ORs) (95% confidence intervals [CIs]) were 0.72 (0.58-0.89) for point depressiveness/anxiety and 0.73 (0.56-0.94) for depressiveness lasting for at least 2 weeks. In suicidal ideation, the OR (95% CI) of eating with family twice a day was significant after full adjusting for covariates at 0.67 (0.50-0.88). Conclusion: Family mealtimes were closely associated with depressive symptoms in elderly Koreans, which suggests that maintaining intrafamilial bonding is important for mental health in an older population.

• Women's Health Nursing
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• v.25 no.3
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• pp.299-314
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• 2019

Purpose: This study was to identify health behavior, health service use, and health related quality of life of adult women in one-person and multi-person households. Methods: It was used data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES VII-2017). Subjects were 2,522 women with age of 19 to 64 years in 2017. Complex sampling design and data analysis were performed using SPSS 20.1. Results: Women in one-person households had higher rates of alcohol drinking (${\chi}^2=13.77$, p=.003), smoking (${\chi}^2=16.07$, p=.001), unmet medical care (${\chi}^2=8.77$, p=.004) and non-practice of cancer screening (${\chi}^2=13.77$, p=.003) compared to women in multi-person households. Health-related quality of life was also lower for women in one-person households (t=-2.46, p=.015). Factors affecting health-related quality of life in one-person households were household income, job status, and unmet dental care, having 32.4% explanatory power. One-person household women with low incomes, no jobs, and unmet dental care showed low health-related quality of life. In comparison, factors affecting health-related quality of life of women in multi-person household women were age, education level, unmet medical care, and unmet dental care, having 10.4% explaining power. Women in multi-person households with age of 60-64, low education level, unmet medical care, and unmet dental care showed low health-related quality of life. Conclusion: Health promotion strategies should be developed based on unique understanding of social, economic, and health of adult women in one-person and multi-person households.

• Journal of Korean society of Dental Hygiene
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• v.19 no.5
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• pp.715-729
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• 2019

Objectives: This study aimed to validate the moderating effect of oral health on the relationship between perceived health status and health-related quality of life in the elderly and to use this information as primary data to suggest oral health policies for the aged society. Methods: This study included 3,707 subjects aged over 65 years who answered all the variables used in the study model and completed the health questionnaire and screening survey based on the sixth Korea National Health and Nutrition Examination Survey. Baron & Kenny's linear regression analysis using SPSS 22.0 and SPSS Macro Version 3.1 programs was performed to confirm the moderating effect of the number of remaining natural teeth, chewing difficulty, and cardiovascular disease on the relationship between perceived health status and healthrelated quality of life in the elderly. Results: The number of remaining natural teeth, chewing difficulties, and cardiovascular diseases affected the perceived health status of the elderly. As the number of remaining natural teeth increased, the effect of perceived health status on the quality of life in the elderly was buffered. The effect of perceived health status on the quality of life increased with chewing difficulties and the number of cardiovascular diseases. In particular, it was confirmed that chewing difficulties, rather than the number of cardiovascular diseases. had a greater effect on the quality of life in the elderly. Conclusions: Oral health policies and projects are required to ensure oral rehabilitation with dentures and implants and restore chewing function to improve the quality of life of the elderly in Korea.