• Archives of Pharmacal Research
• /
• 제28권5호
• /
• pp.598-603
• /
• 2005

The purpose of this study was to determine the influence of weight with gentamicin assay error on the Bayesian and nonlinear least squares regression analysis in 12 Korean appen dicitis patients. Gentamicin was administered intravenously over 0.5 h every 8 h. Three specimens were collected at 48 h after the first dose from all patients at the following times, just before regularly scheduled infusion, at 0.5 h and 2 h after the end of 0.5 h infusion. Serum gentamicin levels were analyzed by fluorescence polarization immunoassay technique with TDxFLx. The standard deviation (SD) of the assay over its working range had been determined at the serum gentamicin concentrations of 0, 2, 4, 8, 12, and 16 ${\mu}g$/mL in quadruplicate. The polynominal equation of gentamicin assay error was found to be SD (${\mu}g$/mL) = 0.0246-(0.0495C)+ (0.00203C$^2$). There were differences in the influence of weight with gentamicin assay error on pharmacokinetic parameters of gentamicin using the nonlinear least squares regression analysis but there were no differences on the Bayesian analysis. This polynominal equation can be used to improve the precision of fitting of pharmacokinetic models to optimize the process of model simulation both for population and for individualized pharmacokinetic models. The result would be improved dosage regimens and better, safer care of patients receiving gentamicin.

• Journal of Korean Biological Nursing Science
• /
• 제15권3호
• /
• pp.147-153
• /
• 2013

Purpose: This study was conducted in order to closely examine the effects on bone mineral density and health promotion behaviors following the intervention of a 20-week Thera band exercise program targeting elderly women. Methods: This study is a pseudo-experimental research with a pre-and-post design in a single group that examined the effects after the intervention of Thera Band Exercise for 20 weeks targeting 31 elderly women over 60 years of age who visit a Senior Welfare Center located in K city. It analyzed subjects' general characteristics using error and percentage, health promotion behavior, and a bone density aspect using the mean and standard deviation, as well as a change in the health promotion behavior and bone density, before and after exercise with Paired t-test by using the SPSS 18.0 program. Results: The effect of the Thera band exercise program on bone mineral density was reduced (t=8.140, p<.001) gradually after 20 weeks of exercise compared to the pre-exercise period. The health promotion behavior before and after exercise showed the significantly increasing outcomes (t=3.26, p=.003). Conclusion: There is a limitation to a direct rise in bone mineral density with the use of Thera band exercise intervention in the elderly. A change in health promotion behavior before and after exercise increased significantly. Thus, it was confirmed that taking exercise leads to a gradual rise in health promotion behavior. Hence, it understood that continuous exercise is useful and brings about a positive change in promoting health maintenance in elderly women.

• 간호행정학회지
• /
• 제21권5호
• /
• pp.542-551
• /
• 2015

Purpose: This study was done to evaluate validity and reliability of the Korean version of the expanded nursing stress scale (ENSS). Methods: Forward-backward translation of ENSS from English to Korean was conducted. The translated instrument was pilot-tested and administrated to 285 nurses who worked in five general hospitals in Korea. Internal consistency reliability was assessed using Cronbach's ${\alpha}$ and composite reliability. Validity was evaluated through construct validity with confirmatory factor analysis, convergent and discriminant validity. Results: The Korean version of ENSS showed a reliable internal consistency with Cronbach's ${\alpha}$ .95 and composite reliability .99. Model fit indexes for 46 items were validated by confirmatory factor analysis(goodness of fit index .82, Tucker-Lewis index .92, root mean square error of approximation .04), indicating suitable construct validity. Factor loading of the 48 items (.47~.88) and average variance extracted out of nine factors (.52~.71.) indicated satisfactory convergent validity. Some values of square of the correlation coefficient between factors (.12~.89) were higher than average variance extracted values of each factor (.52~.71) so that it partly satisfied discriminant validity. Conclusion: Findings show that the Korean version ENSS has good reliability and suitable validity; therefore, can be used to assess and identify Korean nurses' job stress.

• 대한간호학회지
• /
• 제49권2호
• /
• pp.191-202
• /
• 2019

Purpose: Patient-centered care is a widely utilized concept in nursing and health care. However, the key components of patient-centered nursing have not yet been reported. Moreover, previous studies on patient-centered care have mostly focused on components of nursing rather than organizational factors. Therefore, a comprehensive understanding of influential factors of patient-centered care is required. Methods: The purpose of this study was to develop a theoretical model based on person-centered care theory, and the relevant literature and to test the developed model with covariance structure analysis in order to determine the causal paths among the variables. Results: The model fit indices for the hypothetical model were suitable for the recommended level (goodness of fit index=.87, standardized root mean residual=.01, root mean square error of approximation=.06, Tucker-Lewis index=.90, comparative fit index=.92, parsimonious normed fit index=.75). In this study, five of the six paths established in the initial hypothetical model were supported. The variables of teamwork, self-leadership, and empathy accounted for 56.4% of hospital nurses' patient-centered care. Among these, empathy was the strongest predictor of patient-centered care. Conclusion: These results suggest that it is necessary to use strategies to improve self-leadership and empathy. In addition to enhancing the personal factors of nurses, nursing organizations should strive for effective multidisciplinary cooperation with active support for patient-centered care and openness to change.

• Journal of the Optical Society of Korea
• /
• 제17권4호
• /
• pp.328-335
• /
• 2013

Due to the rapid advancement of auto-refractor technology, most optometry shops provide refraction services. Despite their speed and convenience, the measurement values provided by auto-refractors include a significant degree of error due to psychological and physical factors. Therefore, there is a need for repetitive testing to obtain a smaller mean error value. However, even repetitive testing itself might not be sufficient to ensure accurate measurements. Therefore, research on a method of measurement that can complement auto-refractor measurements and provide confirmation of refraction results needs to be conducted. The customized optometry model described herein can satisfy the above requirements. With existing technologies, using human eye measurement devices to obtain relevant individual optical feature parameters is no longer difficult, and these parameters allow us to construct an optometry model for individual eyeballs. They also allow us to compute visual images produced from the optometry model using the CODE V macro programming language before recognizing the diffraction effects visual images with the neural network algorithm to obtain the accurate refractive diopter. This study attempts to combine the optometry model with the back-propagation neural network and achieve a double check recognition effect by complementing the auto-refractor. Results show that the accuracy achieved was above 98% and that this application could significantly enhance the service quality of refraction.

• 대한의용생체공학회:의공학회지
• /
• 제28권2호
• /
• pp.178-186
• /
• 2007

This study is attempted to correct an error of electronic blood pressure meter with an optical sensor. In general, for a hospitalized patient, ECG, blood pressure, oxygen saturation, and respiration are basically measured to monitor the patient's condition. Opening of a blood vessel after it is occluded by pressurizing the cuff influences the blood flow of peripheral blood vessels as well as oscillation changes in the cuff. Blood vessels are occluded and peripheral blood flow disappears at cuff pressure above the examinee's blood pressure, while blood vessels are opened and peripheral blood flow appears again at cuff pressure under the examinee's blood pressure. Then Disappear-Appear Point Length(DAPL) of peripheral blood flow can be judged with the signal of peripheral blood flow, thus is available as a factor of error correction for electronic blood pressure meter. Also, systolic or diastolic blood pressure can be corrected with Appear-Point-Pressure(APP) of cuff pressure at a point where blood flow occurs and Appear-Maximum Pressure(AMP) of cuff pressure at the maximum amplitude point of peripheral blood flow after peripheral blood flow appears again. For verification, 27 examinees were selected, and their blood value was obtained through experimental procedure of 4 stages including induction of blood pressure change. The examinees were divided into two groups of experimental group and control group, regression analysis was conducted for experimental group, and correction of a blood pressure error was verified with optical signal by applying the regression equation calculated in experimental group to control group. As an experimental result, mean of the whole measurement errors was 5mmHg or more, which did not meet the standard fur blood pressure meter. As a result of correcting blood pressure measurements with data of DAPL, APP, and AMP as drawn out of PPG signal, systolic blood pressure, mean blood pressure, and diastolic blood pressure were $-0.6{\pm}4.4mmHg,\;-1.0{\pm}3.9mmHg$ and $-1.3{\pm}5.4mmHg$, respectively, indicating that mean of the whole measurement errors was greatly improved, and standard deviation was decreased.

• 지역사회간호학회지
• /
• 제25권4호
• /
• pp.270-281
• /
• 2014

Purpose: The purpose of the study was to understand low-income elders' experiences of community-based u-Health services. Methods: Qualitative data were collected from 11 participants. All interviews were recorded and transcribed verbatim. The transcribed data were analyzed using qualitative content analysis. Results: Three themes and eight sub-themes emerged as a result of analysis. The three main themes were 'recovered confidence and health condition,' 'trial and error in change,' and 'hope.'The eight sub-themes were 'the burden and efforts to overcome it in using bio-signal device,' 'ambivalence due to changing lifestyle,' 'increase of care time, decrease of pressure', 'conflict under environmental constraints,' 'difficulty in prioritizing health management,' 'discouragement in handling new devices,' 'desire not to be a burden to their children-gradual fulfillment of learning needs,' and 'long for broadening coverage range of services.' Conclusion: The findings of this study demonstrate that low-income elders among the participants have different needs in using u-Health services. Therefore, health professionals need to give personalized education to deal with their conflicts and requirements, especially emotional and environmental support in order for them to successfully accept the u-Health services for self-care.

• Child Health Nursing Research
• /
• 제26권1호
• /
• pp.35-46
• /
• 2020

Purpose: The purpose of this study was to test a model for intention to discontinuation drinking high caffeinated beverages among undergraduate students. This model was based on the Ajzen's theory of planned behavior and Becker's health belief model. Methods: Participants consisted of 201 undergraduate students. Data were collected by questionnaires from March 11 to May 24, 2019. Collected data were analyzed using SPSS/WIN 22.0, AMOS 22.0 program. Results: The assessment of the model indicated an acceptable fit (normed x²=1.65, goodness-of-fit index [GFI]=.83, adjusted GFI=.79, comparative fit index [CFI]=.92, standardized root mean square residual [SRMR]=.05, Tucker-Lewis index [TLI]=.91, normed fit index [NFI]=.87, root mean square error of approximation [RMSEA]=.07). Perceived behavior control, subjective norm, the subjective attitude was found to have a significant direct effect on the intention to discontinuation of drinking a high caffeinated beverage. The variances of this model explained 45.3% of the variance in intention to discontinuation of drinking a high caffeinated beverage. Conclusion: These results suggest that a need to increase awareness of adverse effects and potential risks of high caffeinated beverage consumption in undergraduate students. Besides, the university and government should provide education and campaigns to prevent excessive high-caffeinated beverage consumption.

• Child Health Nursing Research
• /
• 제22권2호
• /
• pp.126-136
• /
• 2016

Purpose: The purposes of this review were to address misconceptions of childhood fever and fever management practice among parents and health care providers, and to identify the scientific evidences against such misconceptions and practices. Methods: Journal databases and clinical guidelines from 2000 to 2015 were searched. The search terms were fever, fever management, misconception, myth, fiction, fact, fever phobia, child, antipyretics, tepid bath, alternating use/combined use of antipyretics, and physical cooling method. Results: There are significant gaps between current concepts and practices, and the scientific evidence. Misconceptions and unrealistic concerns about childhood fever still exist among parents and even health care providers, worldwide. The evidences suggest that antipyretics should be given carefully with the aim of relieving discomfort or pain rather than decreasing the temperature itself. Alternating use of antipyretics should be discouraged due to the risk of confusion and error. Antipyretics do not prevent febrile convulsions. Moreover, the scientific evidence does not support tepid sponge massage. Conclusion: Evidence-based childhood fever management interventions should be targeted toward parents and health care providers. By adopting an evidence-based approach to nursing interventions, pediatric nurses can ensure children receive appropriate and safe fever management.

• 가정간호학회지
• /
• 제24권1호
• /
• pp.87-98
• /
• 2017

Purpose: The purpose of this study was to investigate the factors affecting medication errors and the medication management educational needs of community-dwelling older adults. Methods: From February 20 to February 23, 2017, 150 elderly people aged 65 or older were surveyed using a structured questionnaire. Results: A total of 85.7% of the older adults were taking medication, but their drug knowledge was found to be low. The medication error rate was 24.9%, and the score for medication management education requirement was 3.61 out of a possible 5points. Factors affecting medication errors were perceived health status and knowledge of medication, and their explanatory power was 43% in total. Conclusion: It was concluded that nursing intervention is needed to reduce older adults' medication errors and to increase their knowledge of medication. Additionally, groups of older adults with high medication errors should be intensively educated, and when developing a medication management education program, the contents of the sub-areas and items in which the participants' needs were high should be reinforced.