• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.42 no.1
• /
• pp.111-118
• /
• 2005

The shape of vertical pattern of base station antenna affects greatly quality of the communication of not only a service zone but also adjacent cells and then it is an important point to be considered in designing cell coverage. Currently type of vertical patterns to be applied to base station antenna are divided into five classes. In designing antenna, these five classes are applied solely or compositely according to the environment to be used antenna. In this paper, the dual polarized antenna for base station that is with a continuous electrical down tilting and with a shaped beam pattern, that an upper side lobe is suppressed and a lower null is filled, is designed and fabricated for synthesizing of the shape beant the pattern synthesis methods proposed by R. S. Elliott is used sequentially and for the electrical don tilting, the phased array theory is applied. Measured results show the down tilting range from 0° to 14°, the gain of Min. 13.3dBi and the upper side lobe of Max. -23dB. And we verified that upper side lobe is not to vary greatly and null filling performance is favorable overall.

• Animal Bioscience
• /
• v.36 no.12
• /
• pp.1905-1917
• /
• 2023

Objective: Nanog homeobox (NANOG) is a core transcription factor that contributes to pluripotency along with octamer binding transcription factor-4 (OCT4) and sex determining region-Y box-2 (SOX2). It is an epiblast lineage marker in mammalian pre-implantation embryos and exhibits a species-specific expression pattern. Therefore, it is important to understand the lineage of NANOG, the trophectoderm, and the primitive endoderm in the pig embryo. Methods: A loss- and gain-of-function analysis was done to determine the role of NANOG in lineage specification in parthenogenetic porcine blastocysts. We analyzed the relationship between NANOG and pluripotent core transcription factors and other lineage makers. Results: In NANOG-null late blastocysts, OCT4-, SOX2-, and SOX17-positive cells were decreased, whereas GATA binding protein 6 (GATA6)-positive cells were increased. Quantitative real-time polymerase chain reaction revealed that the expression of SOX2 was decreased in NANOG-null blastocysts, whereas that of primitive endoderm makers, except SOX17, was increased. In NANOG-overexpressing blastocysts, caudal type homeobox 2 (CDX2-), SOX17-, and GATA6-positive cells were decreased. The results indicated that the expression of primitive endoderm markers and trophectoderm-related genes was decreased. Conclusion: Taken together, the results demonstrate that NANOG is involved in the epiblast and primitive endoderm differentiation and is essential for maintaining pluripotency within the epiblast.

• Asian-Australasian Journal of Animal Sciences
• /
• v.21 no.5
• /
• pp.745-753
• /
• 2008

Gene-manipulated mice were discovered for the first time about a quarter century ago. Since then, numerous sophisticated technologies have been developed and applied to answer key questions about the fundamental roles of the genes of interest. Functional genomics can be characterized into gain-of-function and loss-of-function, which are called transgenic and knock-out studies, respectively. To make transgenic mice, the most widely used technique is the microinjection of transgene-containing vectors into the embryonic pronucleus. However, there are critical drawbacks: namely position effects, integration of unknown copies of a foreign gene, and instability of the foreign DNA within the host genome. To overcome these problems, the ROSA26 locus was used for the knock-in site of a transgene. Usage of this locus is discussed for the gain of function study as well as for several brilliant approaches such as conditional/inducible transgenic system, reproducible/inducible knockdown system, specific cell ablation by Cre-mediated expression of DTA, Cre-ERTM mice as a useful tool for temporal gene regulation, MORE mice as a germ line delete and site specific recombinase system. Techniques to make null mutant mice include complicated steps: vector design and construction, colony selection of embryonic stem (ES) cells, production of chimera mice, confirmation of germ line transmission, and so forth. It is tedious and labor intensive work and difficult to approach. Thus, it is not readily accessible by most researchers. In order to overcome such limitations, technical breakthroughs such as reporter knock-in and gene knock-out system, production of homozygous mutant ES cells from a single targeting vector, and production of mutant mice from tetraploid embryos are developed. With these upcoming progresses, it is important to consider how we could develop these systems further and expand to other animal models such as pigs and monkeys that have more physiological similarities to humans.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.31 no.12A
• /
• pp.1214-1222
• /
• 2006

In this paper, an efficient direction-r)f-arrival based adaptive beamforming algorithm for orthogonal frequency-division multiple-access smart antenna systems is proposed. The proposed algorithm provides a high performance by steering main beams to the directions of a desired signal, whereas steering nulls to the directions of the interference, using the estimated directions. The beamforming outputs obtained by steering the main beams to the distinct directions of resolvable multipath signals are combined in a maximal ratio manner to exploit angular diversity gain. The performance elf the proposed algorithm is finally evaluated in cellular mobile environments to verify its efficiency and is compared with that of least-squares beamforming algorithm, by taking the WiBro system as a target system.

• ETRI Journal
• /
• v.38 no.2
• /
• pp.291-301
• /
• 2016

In this paper, we study an optimized block-diagonal zero-forcing (BD-ZF) precoder in a two-tiered cognitive network consisting of a macro cell (MC) and a small cell (SC). By exploiting multiuser multiple-input and multiple-output Vandermonde-subspace frequency-division multiplexing (VFDM) transmission, a cognitive SC can coexist with an MC. We first devise a cross-tier precoder based on the idea of VFDM to cancel the interference from the SC to the MC. Then, we propose an optimized BD-ZF intra-tier precoder (ITP) to suppress multiuser interference and maximize the throughput in the SC. In the case where the dimension of a provided null space is larger than that required by the BD-ZF ITP, the optimized BD-ZF ITP can collect all limited channel gain by optimizing rotating and selecting matrices. Otherwise, the optimized BD-ZF ITP is validated to be equivalent to the conventional BD-ZF ITP in terms of throughput. Numerical results are presented to demonstrate the throughput improvement of the proposed optimized BD-ZF ITP and to discover the impact of imperfect channel state information.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.21 no.3
• /
• pp.612-621
• /
• 1996

In this paper, we propose the low sidelobe digital FIR doppler filter bank synthesis algorithm through the Gradient Descent method and it can be practially appliable to coherent pulse doppler radar signal processing. This algorithm shows the appropriate calculation of tap coefficients or zeros for FIR transversal fiter which has been employed in radar signal processor. The span of the filters in the filter bank be selected at the desired position the designer want to locate, and the lower sidelobe level that has equal ripple property is achieved than one for which the conventional weithtedwindow is used. Especially, when we implemented filter zeros as design parameters it is possible to make null filter gain at zero frequency intensionally that would be very efficient for the eliminatio of ground clutter. For the example of 10 tap filter synthesis, when filter coefficients or zeros are selected as design parameters the corresponding sidelobelevel is reducedto -70db or -100db respectively and it has good convergent characteristics to the desired sidelobe reference value. The accuracy ofapproach to the reference value and the speed of convergence that show the performance measure of this algorithm are tuned out with some superiority and the fact that the bandwidth of filter appears small with respect to one which is made by conventional weighted window method is convinced. Since the filter which is synthesized by this algorithm can remove the clutter without loss of target signal it strongly contributes performance improvement with which detection capability would be concerned.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.38A no.12
• /
• pp.1030-1038
• /
• 2013

The proposed Alamouti coded OFDM effectively cancels Inter Carrier Interference (ICI) due to frequency offset between distributed antennas. The conventional Alamouti coded OFDM schemes to mitigate ICI utilize N-point Inverse Fast Fourier Transform/Fast Fourier Transform (IFFT/FFT) operations for OFDM modulation and demodulation processes with total N subcarriers. However, the performance degrades because ICI is also repeated in N periods due to the property of N-point IFFT/FFT operation. In order to avoid this problem, null data are used at the subcarriers with large ICI and thus, data rate decreases. The proposed scheme employs 2N-point IFFT/FFT instead of N-point IFFT/FFT in order to increase sampling rate. By increasing sampling rate, the amount of interference significantly decreases because the period of ICI also increases. The proposed scheme increases the data rate and improves the performance by reducing amount of ICI and the number of null-data. Furthermore, the gain of the performance and data rate of the proposed scheme is significant with higher modulation such as 16-Quadarature Amplitude Modulation (QAM) or 64-QAM.

• Korean Journal of Veterinary Research
• /
• v.34 no.2
• /
• pp.275-286
• /
• 1994

Plasma protein which has been known as one of nonspecific immunostimulators was added to feedstuff to examine its effect on the enhancement of cellular immune response in porcine immune system. A total of 40 piglets, 20 male and 20 female each, were fed for 30 days with or without plasma protein. The peripheral blood were collected and analyzed for the investigation of leukocyte subpopulations and their activities by using a panel of monoclonal antibodies specific to porcine leukocyte differentiation antigens and flow cytometry. The results obtained as follows. 1. Total weight gain, daily feed intake and feed conversion rate for 10 days were significantly improved to 56%, 20% and 22% in the piglets fed plasma protein, respectively. 2. A significant increase in N (null or non T/non B) cells was also noticed. Leukocyte proportion from piglets fed plasma protein was 20.2-24.7%, otherwise that from piglets fed without plasma protein was 12.3-13.4%, respectively. 3. A significant increase in the proportion of B cells and cells expressing poCD1 was not found in piglets fed plasma protein. 4. Reaction with monoclonal antibodies specific to adhesion molecules, poCD11a, poCD11b, poCD44 and poCD45A and poCD45B, has shown that leukocyte subpopulation from piglets fed plasma protein did not significantly higher than that from piglets fed without plasma protein. 5. Total proportion of granulocytes and monocytes was about 50% in both group and the proportion after treated with Hypaque/Ficoll was 2.7% and 5.8% in each group, respectively.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.27 no.1
• /
• pp.8-13
• /
• 2016

A pattern-switchable origami antenna is designed with paper using inkjet-printing technology. The proposed antenna can be switched between loop and dipole antenna modes by folding and unfolding the paper, respectively. The proposed antenna is designed for the resonant frequencies of both modes to be 1.85 GHz. Eutectic gallium-indium liquid metal is introduced in order to avoid cracks in the conductive ink when the paper is folded. The performance of the proposed antenna is demonstrated through simulation and measurement results and antenna gain of dipole-mode and loop-mode are -4 dBi and -5 dBi, respectively. Also, the nulls of both dipole and loop modes compensate nulls from each mode.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.20 no.3
• /
• pp.273-279
• /
• 2009

In this paper, an antenna which has dipole-like radiation pattern and low profile is proposed. The antenna is composed of four elements slot array based on L-shaped 0.43 $\lambda_g$ slot element. It presents a omni-directional radiation patter in the azimuth plane and has a null toward broad-side direction. In the design, a small mono-pole antenna which acts as a large capacitance element, combined with the partially removed ground plane by four L-shaped slots. As a result, these structure act as a LC resonator for radiation. The measured result shows, the impedance bandwidth(VSWR$\leq$2) of the proposed antenna is 60 MHz(2.35$\sim$2.41 GHz). The measured maximum radiation gain and efficiency of proposed antenna is 0.02 dBi, 56.7 % at center frequency 2.38 GHz, respectively. The proposed antenna can be applied to wireless tan access point system.