• Title/Summary/Keyword: Nuclear medicine study

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Quantitation of In-Vivo Physiological Function using Nuclear Medicine Imaging and Tracer Kinetic Analysis Methods (핵의학 영상과 추적자 동력학 분석법을 이용한 생체기능 정량화)

  • Kim, Su-Jin;Kim, Kyeong-Min;Lee, Jae-Sung
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.2
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    • pp.145-152
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    • 2008
  • Nuclear medicine imaging has an unique advantage of absolute quantitation of radioactivity concentration in body. Tracer kinetic analysis has been known as an useful investigation methods in quantitative study of in-vivo physiological function. The use of nuclear medicine imaging and kinetic analysis together can provide more useful and powerful intuition in understanding biochemical and molecular phenomena in body. There have been many development and improvement in kinetic analysis methodologies, but the conventional basic concept of kinetic analysis is still essential and required for further advanced study using new radiopharmaceuticals and hybrid molecular imaging techniques. In this paper, the basic theory of kinetic analysis and imaging techniques for suppressing noise were summarized.

Nuclear Medicine Imaging Instrumentations for Molecular Imaging (분자영상 획득을 위한 핵의학 영상기기)

  • Chung, Yong-Hyun;Song, Tae-Yong;Choi, Yong
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.2
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    • pp.131-139
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    • 2004
  • Small animal models are extensively utilized in the study of biomedical sciences. Current animal experiments and analysis are largely restricted to in vitro measurements and need to sacrifice animals to perform tissue or molecular analysis. This prevents researchers from observing in vivo the natural evolution of the process under study. Imaging techniques can provide repeatedly in vivo anatomic and molecular information noninvasively. Small animal imaging systems have been developed to assess biological process in experimental animals and increasingly employed in the field of molecular imaging studies. This review outlines the current developments in nuclear medicine imaging instrumentations including fused multi-modality imaging systems for small animal imaging.

Diagnosis of Coronary Artery Disease Using Myocardial Perfusion SPECT (심근 SPECT를 이용한 관상동맥질환의 진단)

  • Won, Kyoung-Sook;Kim, Hae-Won
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.3
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    • pp.196-202
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    • 2009
  • Myocardial perfusion scintigraphy is currently by far the most commonly performed cardiac nuclear study, constituting approximately one third of all nuclear medicine procedure. It plays an important role in the diagnosis, prognosis, risk assessment and management of heart disease. Aim of this review is to describe recent evolution of myocardial perfusion imaging on the focus of diagnosis of coronary artery disease. In addition, current status of other imaging modalities will be reviewed.