• The Korea Journal of Herbology
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• v.32 no.2
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• pp.25-32
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• 2017

Objectives : This study was conducted to investigate candidate materials as anti-inflammatory agent from extracts of Korean medicinal plants in Hwaak mountain. Ligustrum obtusifolium (LO) is a Korea medicinal plants that commonly used for robustness and hemostasis. It has been reported that LO has exhibited anti-ischemic, anti-oxidative, anti-hypolipidemic, anti-tumor and hypoglycemic effects. However, LO has not been previously reported to have an anti-inflammatory effect. Therefore, we have evaluated the anti-inflammatory effects of LO and its underlying molecular mechanisms in LPS-induced RAW 264.7 macrophages. Methods : Cell viability was determined by MTT assay in RAW 264.7 macrophages. Nitric Oxide (NO) was measured with Griess reagent and pro-inflammatory cytokines were detected by ELISA in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Protein expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and p65 subunit of nuclear $factor-{\kappa}B$ ($NF-{\kappa}B$) were determined by Western blot analysis. Results : Among 15 extracts of Korean medicinal plants tested, Ligustrum obtusifolium (LO) showed the inhibition of NO production without cytotoxicity. LO reduced the expression levels of iNOS and COX-2 proteins in LPS-simulated RAW 264.7 macrophages in dose-dependent manner. Consistent with these data, LO inhibited the productions of $TNF-{\alpha}$, IL-6, and $IL-1{\beta}$ in LPS-simulated RAW 264.7 macrophages. Furthermore, LO attenuated the LPS-induced nuclear translocation of p65 $NF-{\kappa}B$ in RAW 264.7 macrophages involving suppression of $NF-{\kappa}B$ activation. Conclusions : Taken together, these results suggest that the anti-inflammatory effects of LO is associated with regulation of inflammatory mediators via inhibition of $NF-{\kappa}B$ activation in LPS-treated RAW 264.7 macrophages.

• Environmental and Resource Economics Review
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• v.31 no.4
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• pp.865-885
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• 2022

Korean government updated her Nationally Determined Contribution (NDC) in 2021 and announced the target and various measures for reductions. Among the many issues, final energy demand and renewable energy power mix for 17 provinces to achieve the target are being analyzed using GCAM-Korea. Simulation results show that final energy demand of 2030 is approximated at the similar level to that of 2018. This is being enabled by the conservation of coal with higher electrification especially in industry sector. Higher power demand with lower coal consumption in final energy consumption is shown to be provided by 33.1% of renewable, 24.6% of gas, and 18.0% of nuclear power generation in 2030. Meanwhile, the share of coal-fired power generation is expected to be reduced to 12.8%. Major future power provider becomes Gyeongbuk (Nuclear), Gyeonggi (Gas), Jeonnam (Nuclear, Gas) and Gangwon (PV, Wind), compared to one of current major power provider Chungnam (Coal). This analysis is expected to provide a useful insight toward the national and provincial energy and climate change policy.

• Food Science and Biotechnology
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• v.17 no.1
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• pp.188-190
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• 2008

In east Asia, the leaves of various Sasa species have been used in folk medicine for centuries. The effects of the methanolic extract and its subsequent fractions derived from the leaves of Sasa quelpaertensis Nakai on cell proliferation in human leukemia HL-60 cells were evaluated. The ethyl acetate fraction of this extract (ESQL) significantly reduced cell viability in a dose-dependent manner ($0-250\;{\mu}g/mL$). ESQL ($IC_{50}=24.8\;{\mu}g/mL$) exhibited growth inhibition comparable to the main constituent of green tea, epigallocatechin ($IC_{50}=26.2\;{\mu}g/mL$), which was used as a positive control. ESQL treatment induced apoptosis, which was confirmed by the presence of nuclear condensation and annexin V-staining. These results demonstrate that ESQL contains chemopreventive phytochemicals that may be useful in neutraceutical applications.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 1991.11a
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• pp.38-43
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• 1991

일반 금속재료로써 표면층이 최적의 tribology적 성질을 갖도록 하기에는 한계점이 있으며, 이러한 문제점을 해결하기 위한 수단으로 bulk material에 그것이 갖지 못하는 tribology적으로 우수한 성질을 그 표면층에 부여하는 기술로 여러가지 방법이 개발되어 왔으며 그 중 대표적인 것이 표면코팅기술이다. 표면 코팅기술중에서도 세라믹코팅기술이 최근에 들어 최고의 관심사가 되고 있는데 이는 세라믹재의 특징이 고강도, 고경도, 내산화성 및 내화학적 성질 등 기계 요소가 받는 가혹한 조건에 최적의 내성을 지니기 때문이다. 특히 세라믹재가 갖는 고강도, 고경도의 성질은 마찰, 맘모 특성의 향상을 극대화시킬 수 있기 때문에 마찰, 마모가 문제시되는 기계요소에의 적용전망은 매우 밝으며, 특히 취약한 환경 즉, nuclear industry와 우주산업 등과 같이 재래의 윤활기술이 제대로 적용될 수 없는 분야에 세라믹코팅기술의 응용은 절대적으로 필요하다. 현재 세라믹 재료의 마찰과 마모특성에 대한 연구는 전 세계적으로 비교적 활발히 진행되고 있으나 세라믹 코팅으로서의 세라믹재의 마찰, 마모특성에 대한 연구는 아직 초보단계에 있다고 할 수 있다. 따라서 본 연구에서는 현재 응용범위를 넓혀가고 있는 TiN을 cathodic arc evporation(CAE)-기술을 이요하여 모재에 코팅을 하여 그 증착층의 재료적 특성 및 마모특성에 대하여 고찰하였다.

• Structural Engineering and Mechanics
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• v.18 no.3
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• pp.343-362
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• 2004

Rocking response of rigid bodies with rectangular footprint, freely standing on horizontal rigid plane is studied analytically. Bodies are subjected to simulated single component of horizontal earthquakes. The effect of baseline correction, applied to simulated excitations, on the rocking response is first examined. The sensitiveness of rocking motion to the details of earthquakes and geometric properties of rigid bodies is investigated. Due to the demonstrated sensitivity of rocking response to these factors, prediction of rocking stability must be made in the framework of probability theory. Therefore, using a large number of simulated earthquakes, the effects of duration and shape of intensity function of simulated earthquakes on overturning probability of rigid bodies are studied. In the case when a rigid body is placed on any floor of a building, the corresponding probability is compared to that of a body placed on the ground. For this purpose, several shear frames are employed. Finally, the viability of the energy balance equation, which was introduced by Housner in 1963 and widely used by nuclear power industry to estimate the rocking stability of bodies, is evaluated. It is found that the equation is robust. Examples are also given to show how this equation can be used.

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.149-149
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• 2016

Ceramic is widely known material due to its outstanding mechanical property. Besides, Zirconia(ZrO2) has a low thermal conductivity so it is advantage in a heat insulation. Because of these superior properties, ZrO2 is attracted to many fields using ultra high temperature for example vehicle engines, aerospace industry, turbine, nuclear system and so on. However brittle fracture is a disadvantage of the ZrO2. In order to overcome this problem, we can make the ceramic materials to the forms of ceramic nanoparticles, ceramic nanowhiskers and these forms can be used to an agent of composite materials. In this work, we selected Au catalyzed Vapor-Liquid-Solid mechanism to synthesize ZrO2 nanowhiskers. The ZrO2 whiskers are grown through Hot-wall Chemical Vapor Deposition(Hot wall CVD) using ZrCl4 as a powder source and Au film as a catalyst. This Hot wall CVD method is known to comparatively cost effective. The synthesis condition is a temperature of $1100^{\circ}C$, a pressure of 760torr(1atm) and carrier gas(Ar) flow of 500sccm. To observe the morphology of ZrO2 scanning electron microscopy is used and to identify the crystal structure x-ray diffraction is used.

• Journal of the Korean Society for Nondestructive Testing
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• v.29 no.6
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• pp.570-578
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• 2009

Excitation and propagation of guided waves are very complex problems in pipes due to their dispersive nature. Pipes are commonly used in the oil, chemical or nuclear industry and hence must be inspected regularly to ensure continued safe operation. The normal mode expansion(NME) method is given for the amplitude with which any propagating waveguide mode is generated in the pipes by applied surface tractions. Numerical results are calculated based on the NME method using different sources, i.e., non-axisymmetric partial loading and quasi-axisymmetric loading sources. The sum of amplitude coefficients for 0~nineth order of the harmonic modes are calculated based on the NME method and the dispersion curves in pipes. The superimposed total field which is namely the angular profile, varies with propagating distance and circumferential angle. This angular profile of guided waves provides information for setting the transducer position to find defects in pipes.

• Korean Institute of Interior Design Journal
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• v.19 no.2
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• pp.225-233
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• 2010

At this point in time South Korea is rapidly metastasizing to a aging society. A major cause of aging can be summarized as increased life expectancy, decrease of nuclear family and birthrate, and South Korea's progress is faster than any other country. From the 1970s, western society has changed social welfare to deinstitutionalization and community care because of problems about economic reason and facilities protection, so the type of elderly social service has also changed from the facility welfare service which is accommodated old people in certain facility to community welfare service which provides various welfare services with living together. Public facilities for low income group which are supported by government are lower, 6.6%, than the United States or Japan, 50%. They are divided into private manage facilities and subscription elderly facilities. These subscription elderly residential facilities show poor administration because of focusing on development and market analysis for investment returns. Therefore, in order to vitalize the elderly welfare residential facilities in Korea, we need plans about systematic services facilities for welfare and phased medical treatments. Therefore, the purpose of this study is that (1) the types and functions of residents for community elderly residential facilities in elderly welfare policies of U.S., and supported policies are researched as a transcendental model, (2) data about operating system with the principles of the market is analyzed, and (3) basic data about welfare facility plan for community residential elderly people is provided.

• Journal of Ocean Engineering and Technology
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• v.22 no.5
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• pp.100-105
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• 2008

A106 Carbon Steel has recently been used as the material for pipes, nozzles, and tank shells in nuclear power plants. Its corrosion resistance gives the steel many advantages for use in structures under high temperature and high pressure. This steel is also expected to be used as a structural material in the shipbuilding industry for applications involving severe conditions, such as high temperature and pressure. In this study, the mechanical properties of A106 carbon steel were evaluated in regard to its corrosion times. The tensile and yielding strengths decreased as the corrosion time increased. In particular, the tensile strength was influenced by corrosion. In addition, an acoustic emission (AE) technique was used to clarify the microscopic damage to specimens that had undergone corrosion for a certain period. It was found that AE parameters, such as events, energy, duration time, and amplitude were useful for evaluating the degree of damage and remaining life of the corroded specimen. Various properties of the waveform and frequency range were also seen, based on the degree of damage to the specimen from the corrosion time.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.4
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• pp.658-665
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• 2012

Micro-EDM is widely used in metallic pattern, electronics, nuclear power and industry in the form of precision process. The improvement of Electro Discharge Machining has been on a steady progress since $19^{th}$ century. The technology has overcome the limits of the traditional precision process, enabling micro-EDM, micro electrolytic machining, micro drilling, micro punching and laser beam machining, which create versatile products with smaller sizes. What have been known about the major feature of Micro-EDM is high thermal energy so that their products are free from the hardness of their products as long as they are electrical conductor. However, each metal is suspected to have different features and natures even if they are created through the same procedure. In this thesis, the methodology of Micro-EDM and how to categorize them are explained. Also, the nature of the examined materials with surface shape and surface roughnes are analyzed. The results of the experiments are expected to understand surface roughness and workability of other materials for Micro-EDM.