• The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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• v.8 no.4
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• pp.213-220
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• 1979

A number of methods has been developed for calculation of heat transfer in the vertical round tube under conditions of forced convection with uniform heat flux at wall. I would like to express hereby one of applications of this study in the design of heat exchanger instruments for water flow at $15.8^{\circ}C(p_r=8)$ used frequently in our daily life. Also all the results are investigated for forced convective heat transfer in the case of heated water-flow at uniform wall heat flux in the vortical round copper tube, where the ratio of length to diameter will be 44. They are well in agreement with Gratz and Kraussold equation respectively in laminar and transition flow range. In turbulent flow in the range from Re=10,000 to 65,000, the experimental formula Is show as follows ; Nu=0.023 $R_e^{0.814}\;P_r^{0.4}$. And this is agreed with Dittus - Boelter equation when Reynolds number exponent increases from 0.80 to 0.814.

• Journal of Teachers' Pension
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• v.1
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• pp.157-185
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• 2016

본 연구에서는 비정상적 사건을 정의하고 이에 따른 비정상적 위험의 구체적인 유형을 파악하며, 이와 관련된 사학연금의 위험관리 체계에 대한 검토와 함께 비정상적 위험에 효과적으로 대응할 수 있는 자산운용방안을 제시하였다. 우선 비정상적 사건을 '과거 자료를 이용한 발생확률의 추정이나 발생여부에 대한 예측이 불가능하며 따라서 이의 발생 가능성을 사전에 고려하고 대비하는 사전적인 대처가 어려운 사건으로서 자산운용과 위험관리에 무시할 수 없는 영향을 미치는 사건'으로 정의하였으며, 이의 구체적인 형태로서 금융위기를 포함하는 9가지 사건 유형을 파악하였다. 동비정상적 사건들은 포트폴리오 투자를 통한 자산운용에서 개별자산군의 기대수익률과 위험 및 자산군 사이의 상관관계에 영향을 미쳐, 기존의 자산배분안의 최적성을 상실시키고 위험수준의 측정치인 VaR값을 과소 또는 과대추정하게 할 수 있는 것으로 분석되었다. 한편 비정상적 사건의 해외 사례에 대한 분석에서는 비정상적 사건의 영향이 개별 사건마다 다양한 양태로 발현되는 것이 관측되었다. 본 연구에서는 사학연금의 현행 자산배분 체계가 이와 같은 비정상적 사건의 영향에 적절하게 대응하기 어려운 상황이라고 진단하였으며, 비정상적 사건에 적절히 대응하기 위한 자산관리방안의 일환으로서 일별 수익률 자료를 사용한 비정상적 사건의 영향 평가방안을 제시하였다. 한편, 사학연금의 현행 위험관리 체계는 비정상적 사건의 발생에 적절하게 대응할 수 있는 것으로 평가되었다

• Journal of the korean academy of Pediatric Dentistry
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• v.44 no.3
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• pp.306-316
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• 2017

The purpose of this study was to evaluate the effects of exposure to various children's drinks on the color stability of anterior primary teeth and different esthetic restorative materials clinically used in pediatric dentistry. Exfoliated maxillary primary central incisors that had been unaffected by caries were chosen as control group. Maxillary primary central incisor-shaped specimens made of strip crown and Nu-smile zirconia crowns were chosen as test groups. Polished strip resin crowns were additionally prepared to compare with unpolished strip resin crown. Each specimen and teeth were divided into 4 groups in which the test samples (n=5 each) were immersed in 4 different drinks (distilled water, cola, grape juice, jelly juice) for 6 days. In all 4 drink groups, all specimens generally showed increasing ${\Delta}E^*$ value (color difference) with time. Polished resin strip crown had higher ${\Delta}E^*$ value than the unpolished in cola, grape juice and jelly juice groups. ${\Delta}E^*$ value of zirconia crown in cola, grape juice and jelly juice groups were significantly different (p < 0.05). In conclusion, dietary control of children's drinks is required for preventing discoloration of restorative materials.

• Journal of The Korean Astronomical Society
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• v.50 no.6
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• pp.167-178
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• 2017

We present a study of the inexplicit connection between radio jet activity and ${\gamma}$-ray emission of BL Lacertae (BL Lac; 2200+420). We analyze the long-term millimeter activity of BL Lac via interferometric observations with the Korean VLBI Network (KVN) obtained at 22, 43, 86, and 129 GHz simultaneously over three years (from January 2013 to March 2016); during this time, two ${\gamma}$-ray outbursts (in November 2013 and March 2015) can be seen in ${\gamma}$-ray light curves obtained from Fermi observations. The KVN radio core is optically thick at least up to 86 GHz; there is indication that it might be optically thin at higher frequencies. To first order, the radio light curves decay exponentially over the time span covered by our observations, with decay timescales of $411{\pm}85$ days, $352{\pm}79$ days, $310{\pm}57$ days, and $283{\pm}55$ days at 22, 43, 86, and 129 GHz, respectively. Assuming synchrotron cooling, a cooling time of around one year is consistent with magnetic field strengths $B{\sim}2{\mu}T$ and electron Lorentz factors ${\gamma}$ ~ 10 000. Taking into account that our formal measurement errors include intrinsic variability and thus over-estimate the statistical uncertainties, we find that the decay timescale ${\tau}$ scales with frequency ${\nu}$ like ${\tau}{\propto}{\nu}^{-0.2}$. This relation is much shallower than the one expected from opacity effects (core shift), but in agreement with the (sub-)mm radio core being a standing recollimation shock. We do not find convincing radio flux counterparts to the ${\gamma}$-ray outbursts. The spectral evolution is consistent with the 'generalized shock model' of Valtaoja et al. (1992). A temporary increase in the core opacity and the emergence of a knot around the time of the second ${\gamma}$-ray event indicate that this ${\gamma}$-ray outburst might be an 'orphan' flare powered by the 'ring of fire' mechanism.

• Journal of Gastric Cancer
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• v.20 no.1
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• pp.60-71
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• 2020

Purpose: The utility of 18-fluordesoxyglucose positron emission tomography ([¹⁸F]-FDG-PET) combined with computer tomography or magnetic resonance imaging (MRI) in gastric cancer remains controversial and a rationale for patient selection is desired. This study aims to establish a preclinical patient-derived xenograft (PDX) based [¹⁸F]-FDG-PET/MRI protocol for gastric cancer and compare different PDX models regarding tumor growth and FDG uptake. Materials and Methods: Female BALB/c nu/nu mice were implanted orthotopically and subcutaneously with gastric cancer PDX. [¹⁸F]-FDG-PET/MRI scanning protocol evaluation included different tumor sizes, FDG doses, scanning intervals, and organ-specific uptake. FDG avidity of similar PDX cases were compared between ortho- and heterotopic tumor implantation methods. Microscopic and immunohistochemical investigations were performed to confirm tumor growth and correlate the glycolysis markers glucose transporter 1 (GLUT1) and hexokinase 2 (HK2) with FDG uptake. Results: Organ-specific uptake analysis showed specific FDG avidity of the tumor tissue. Standard scanning protocol was determined to include 150 μCi FDG injection dose and scanning after one hour. Comparison of heterotopic and orthotopic implanted mice revealed a long growth interval for orthotopic models with a high uptake in similar PDX tissues. The H-score of GLUT1 and HK2 expression in tumor cells correlated with the measured maximal standardized uptake value values (GLUT1: Pearson r=0.743, P=0.009; HK2: Pearson r=0.605, P=0.049). Conclusions: This preclinical gastric cancer PDX based [¹⁸F]-FDG-PET/MRI protocol reveals tumor specific FDG uptake and shows correlation to glucose metabolic proteins. Our findings provide a PET/MRI PDX model that can be applicable for translational gastric cancer research.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.25 no.6
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• pp.394-404
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• 2013

In the present study, the characteristics of spectral peakedness parameter $Q_p$, bandwidth parameter ${\varepsilon}$, and spectral width parameter ${\nu}$ were analyzed as a first step to define the swell waves quantitatively. For the analysis, the joint probability density function of significant wave heights and peak periods were newly developed. The MCMC(Markov Chain Monte Carlo) simulations have been performed to generate the significant wave heights and peak periods from the developed probability density functions. Applying the simulated significant wave heights and peak periods to the theoretical wave spectrum models, the spectral shapes parameters were obtained and analyzed. Among the spectral shape parameters, only the spectral peakedness parameter $Q_p$, is shown to be independent with the significant wave height and peak wave period. It also best represents the peakedness of the spectral shape, and henceforth $Q_p$ should be used to define the swell waves with a wave period. For the field verification of the results, wave data obtained from Hupo port and Ulleungdo were analyzed and results showed the same trend with the MCMC simulation results.

• Korean Journal of Materials Research
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• v.24 no.11
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• pp.573-577
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• 2014

The existing metal getters are invariably covered with thin oxide layers in air and the native oxide layer must be dissolved into the getter materials for activation. However, high temperature is needed for the activation, which leads to unavoidable deleterious effects on the devices. Therefore, to improve the device efficiency and gas-adsorption properties of the device, it is essential to synthesize the getter with a method that does not require a thermal activation temperature. In this study, getter material was synthesized using palladium oxide (PdOx) which can adsorb $H_2$ gas. To enhance the efficiency of the hydrogen and moisture absorption, a porous layer with a large specific area was fabricated by an etching process and used as supporting substrates. It was confirmed that the moisture-absorption performance of the $SiO_2/Si$ was characterized by water vapor volume with relative humidity. The gas-adsorption properties occurred in the absence of the activation process.

• Toxicological Research
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• v.32 no.3
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• pp.251-258
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• 2016

Mesenchymal stem cells (MSCs) have been identified in multiple types of tissue and exhibit characteristic self-renewal and multi-lineage differentiation abilities. However, the possibility of oncogenic transformation after transplantation is concerning. In this study, we investigated the tumorigenic potential of umbilical cord blood-derived MSCs (hUCB-MSCs) relative to MRC-5 and HeLa cells (negative and positive controls, respectively) both in vitro and in vivo. To evaluate tumorigenicity in vitro, anchorage-independent growth was assessed using the soft agar colony formation assay. hUCB-MSCs and MRC-5 cells formed few colonies, while HeLa cells formed a greater number of larger colonies, indicating that hUCB-MSCs and MRC-5 cells do not have anchorage-independent proliferation potential. To detect tumorigenicity in vivo, hUCB-MSCs were implanted as a single subcutaneous injection into BALB/c-nu mice. No tumor formation was observed in mice transplanted with hUCB-MSCs or MRC-5 cells based on macro- and microscopic examinations; however, all mice transplanted with HeLa cells developed tumors that stained positive for a human gene according to immunohistochemical analysis. In conclusion, hUCB-MSCs do not exhibit tumorigenic potential based on in vitro and in vivo assays under our experimental conditions, providing further evidence of their safety for clinical applications.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.26 no.6
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• pp.381-387
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• 2014

Recently the large-height swell-like waves generated in the eastern coast of South Korea have been observed frequently. The characteristics of the runup and overtopping of the large-height swell-like waves formed in deep water and attack the coast, causing damages to both lives and facilities have been studied. The correlation between spectral shape parameters and significant wave height has been investigated by analyzing long term wave spectrum data. Numerical runup experiments using MIKE21 BW Module were performed with $Q_p$, additional shape parameter, and identified the variations and characteristics of runup heights with respect to the variations of spectral shape.

• Korean Journal of Medicinal Crop Science
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• v.19 no.6
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• pp.441-445
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• 2011

This research was conducted to investigate the influence of variouis organic substrates on growth and yield of organically grown ginseng seedlings in a shaded plastic house. In the investigation of optimal substrate, the eight substrate were formulated by adjusting blending rate of peatmoss, perlite, coir dust(coco peat), and vermiculite. Then, the changes in physico chemical properties of root substrates as well as their influences on the growth characteristics and yield were determined at six months after sowing. The elevation of the blending rate of peatmoss from 50% to 70% with decrease in the rate of inorganic component (mixture of perlite and vermiculite) from 50 to 30% resulted in the increase in container capacities and decrease in total porosities and air-filled capacities. The concentrations of $NH_4-N$, $P_2O_5$ and K increased as the incorporation rate of castor seed meal, phosphate ore, and langbenite, respectively, were elevated during the root medium formulations. The PPV-1 and PPV-4 substrates produced high stem length, stem diameter, shoot fresh weight, leaf area and root length among eight substrate. Root fresh weight was heaviest in PPV-4 compound nursery media. The results of this experiment will be utilized in the new substrate application for ginseng organic culture in shaded vinyl house.