• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제3권2호
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• pp.199-205
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• 2000

Autoimmune enteropathy is a rare chronic diarrheal disease of infancy. Clinicopathologically, this entity is characterized by chronic secretory diarrhea, villous atrophy with crypt hypoplasia of a small intestine and/or associated autoimmune disorders, and absence of severe immunodeficiency. For the confirmation of diagnosis, antienterocyte autoantibody should be delineated. The treatment of choice of this disorder is immunosuppression. We has been experienced a case of autoimmune enteropathy without autoimmune disorders in a 10-month-old male infant. He developed protracted diarrhea from 5 months of his age and has been appeared to be failure to thrive. Antienterocyte autoantibody was demonstrated by immunohistochemistry and western blotting. He was successfully treated with corticosteroid and FK506. This is the first case report of autoimmune enteropathy without autoimmune disorders in Korea.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3109-3116
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• 2013

The majority of hepatocellular carcinoma (HCC) patients have a poor prognosis with current therapies, and new approaches are urgently needed. We have developed a novel therapeutic cancer vaccine platform based on tumor cell derived autophagosomes (DRibbles) for cancer immunotherapy. We here evaluated the effectiveness of DRibbles-pulsed dendritic cell (DC) immunization to induce anti-tumor immunity in BALB/c mouse HCC and humanized HCC mouse models generated by transplantation of human HCC cells (HepG2) into BALB/c-nu mice. DRibbles were enriched from H22 or BNL cells, BALB/c-derived HCC cell lines, by inducing autophagy and blocking protein degradation. DRibbles-pulsed DC immunization induced a specific T cell response against HCC and resulted in significant inhibition of tumor growth compared to mice treated with DCs alone. Antitumor efficacy of the DCs-DRibbles vaccine was also demonstrated in a humanized HCC mouse model. The results indicated that HCC/DRibbles-pulsed DCs immunotherapy might be useful for suppressing the growth of residual tumors after primary therapy of human HCC.

• Elastomers and Composites
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• 제22권3호
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• pp.195-203
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• 1987

In this study, as one of the developing ways of the functional elastomer, improvement of the functionality of CB-BR was attempted through moisture curing reaction. The curing reaction of CB-BR was determined with an use of 3-aminopropyltriethoxysilane(APS) as a crosslinking agent, also a solution reaction with an active chlorine of CB-BR was elucidated by using a reaction kinetics theory and a study of physical property was made through moisture curing on the compound of 3-aminopropyltriethoxysilane and CB-BR The results of this study obtained are as follows : 1) CB-BR reacted easily with APS in the liquid state and the reaction rate coefficient and activation energy were as follows : 2) Optimum pressure condition of moisture cured elastomer(CB-BR+APS) was 20 minutes at $150^{\circ}C$, and the crosslinked elastomer was close to the theoretical value (q=1) for Flory's equation($\frac{\alpha}{\alpha-1}=q{\nu}RT$)

• The Bulletin of The Korean Astronomical Society
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• 제41권1호
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• pp.65.1-65.1
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• 2016

We present results of long-term multi-wavelength polarization observations of the powerful blazar 3C 279 after its ${\gamma}$-ray flare on 2013 December 20. We followed up this flare by means of single-dish polarization observations with two 21-m telescopes of the Korean VLBI Network, carried out weekly from 2013 December 25 to January 11, and at 22, 43, and 86 GHz, simultaneously. These observations were part of the Monitoring Of GAmma-ray Bright AGNs (MOGABA) program. We Measured 3C 279 total flux densities at 22, 43, and 86 GHz, showing a mild variability of a factor of ${\leq}50%$ over the period of our observations. The spectral index ranged from -0.13 to -0.36 at between 22 and 86 GHz. The degree of linear polarization was in the range of 6 ~ 12 %, and slightly decreased with time at all frequencies. We found Faraday rotation measures (RM) of -300 to $-1200rad\;m^{-2}$ between 22 and 43 GHz, and -800 to $-5100rad\;m^{-2}$ between 43 and 86 GHz. The RM values follow a power law ${\mid}RM{\mid}{\propto}{\nu}^{\alpha}$, with a mean ${\alpha}$ of 2.2, implying that the polarized emission at these frequencies travels through a Faraday screen in or near the jet. We conclude that the regions emitting polarized radio emission may be different from the region responsible for the 2013 December ${\gamma}$-ray flare, and that these regions are maintained by the dominant magnetic field perpendicular to the direction of the radio jet at milliarcsecond scales.

• Geophysics and Geophysical Exploration
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• 제10권2호
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• pp.147-153
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• 2007

The conjugate gradient (CG) method is one of the most efficient algorithms for solving a linear system of equations. In addition to being used as a linear equation solver, it can be applied to a least-squares problem. When the CG method is applied to large-scale three-dimensional inversion of magnetotelluric data, two approaches have been pursued; one is the linear CG inversion in which each step of the Gauss-Newton iteration is incompletely solved using a truncated CG technique, and the other is referred to as the nonlinear CG inversion in which CG is directly applied to the minimization of objective functional for a nonlinear inverse problem. In each procedure we only need to compute the effect of the sensitivity matrix or its transpose multiplying an arbitrary vector, significantly reducing the computational requirements needed to do large-scale inversion.

• KIPS Transactions on Software and Data Engineering
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• 제9권1호
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• pp.33-38
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• 2020

This paper proposes a technique for counting construction materials by analyzing an image acquired by a Drone. The proposed technique use drone log which includes drone and camera information, RCNN for predicting construction material type, dummy area and Photogrammetry for counting the number of construction material. The existing research has large error ranges for predicting construction material detection and material dummy area, because of a lack of training data. To reduce the error ranges and improve prediction stability, this paper increases the training data with a method of data augmentation, but only uses rotated training data for data augmentation to prevent overfitting of the training model. For the quantity calculation, we use a drone log containing drones and camera information such as Yaw and FOV, RCNN model to find the pile of building materials in the image and to predict the type. And we synthesize all the information and apply it to the formula suggested in the paper to calculate the actual quantity of material pile. The superiority of the proposed method is demonstrated through experiments.

• The Journal of Internal Korean Medicine
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• 제40권5호
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• pp.957-966
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• 2019

Carbon monoxide intoxication leads to hypoxia, which eventually leads to tissue ischemia. Delayed neuropsychiatric syndrome (DNS) can be a consequence and appears in the form of cognitive impairment and movement disorders after a lucid interval. A 58-year-old Korean male was admitted to our hospital with delayed neuropsychiatric sequelae (DNS) after an 11-day lucid interval following recovery from acute carbon monoxide intoxication. We treated him with herbal medication, acupuncture, electroacupuncture, and moxibustion. The effects were assessed by the activity index and Mini Mental State Examination-Korea (MMSE-K) scores, and by changes in gait disturbance. In this case, the clinical symptoms, including gait disturbance, and the activity index and MMSE-K scores, improved after traditional Korean treatment. The findings of this case report suggest that traditional Korean medicine treatment can be effective for treatment of symptoms of delayed neuropsychiatric sequelae due to CO intoxication.

• Laboraroty Animal Research
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• 제33권2호
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• pp.105-113
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• 2017

insenosides from Panax ginseng are well known for their diverse pharmacological effects including antithrombotic activity. Since adventitious roots of mountain ginseng (ARMG) also contain various ginsenosides, blood flow-improving effects of the dried powder and extract of ARMG were investigated. Rats were orally administered with dried powder (PARMG) or ethanol extract (EARMG) of ARMG (125, 250 or 500 mg/kg) or aspirin (30 mg/kg, a reference control) for 3 weeks. Forty min after the final administration, carotid arterial thrombosis was induced by applying a 70% $FeCl_3$-soaked filter paper outside the arterial wall for 5 min, and the blood flow was monitored with a laser Doppler probe. Both PARMG and EARMG delayed the $FeCl_3$-induced arterial occlusion in a dose-dependent manner, doubling the occlusion time at high doses. In mechanism studies, a high concentration of EARMG inhibited platelet aggregation induced by collagen in vitro. In addition, EARMG improved the blood lipid profiles, decreasing triglyceride and cholesterol levels. Although additional action mechanisms remain to be clarified, it is suggested that ARMG containing high amount of ginsenosides such as $Rg_3$ improves blood flow not only by inhibiting oxidative thrombosis, but also by modifying blood lipid profiles.

• Physical Therapy Korea
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• 제28권3호
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• pp.227-234
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• 2021

Background: The serratus posterior inferior (SPI) muscle originates from the spinous process of T11-L2 and inserts at the lower border of the 9-12th ribs. This muscle is involved in thoracolumbar rotation and stability. Several positions can be used to improve trunk stability; the quadruped position is a good position for easily maintaining a neutral spine. In particular, during one arm lifting, various muscles act to maintain a neutral trunk position, and the SPI is one of these muscles. If trunk stability is weakened, uncontrolled trunk rotation may occur at this time. Tape can be used to increase trunk stability. There have been no studies on the effect of taping applied to the SPI muscle on thoracolumbar junction (TLJ) stability. Objects: This study compared the TLJ rotation angle between three different conditions (without taping, transverse taping, and SPI muscle direction taping). Methods: Thirty subjects were recruited to the study (18 males and 12 females). The TLJ rotation angle was measured during one arm lifting in a quadruped position (ALQP). Two taping methods (transverse and SPI muscle direction taping) were applied, and the TLJ rotation angle was measured in the same movement. Results: SPI muscle direction taping significantly reduced TLJ rotation compared to that without taping (p < 0.001) and with transverse taping (p < 0.001). There was a significant difference in the TLJ rotation angle between transverse taping and SPI muscle direction taping (p < 0.017). Conclusion: SPI muscle direction taping reduces the TLJ rotation angle during ALQP. Therefore, SPI muscle direction taping is one method to improve TLJ stability and reduce uncontrolled TLJ rotation during ALQP.

• Journal of The Geomorphological Association of Korea
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• 제25권2호
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• pp.15-29
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• 2018

The sediment transport process in a river reflects the process of geomorphological change in the watershed, influencesthe river bed variation and the river channel migration, and is a parametric phenomenon that exhibits a dynamic self-adjusting process. Sediment load is divided into bedload and suspended load depending on the dominant mechanism. Quantitative sediment load is important information for solving river problems. Because it is difficult and time consuming to measure bedload, compared to that ofsuspended load, data on the sediment transport load and the research required for the gravel-bed rivers are insufficient. This study is to analyze the ratio of the bedload to the total sediment load in gravel-bed rivers. The sediment load ratio in gravel-bed rivers increases with the flow rate per unit width, and the rate of the bedload varies more rapidly than the suspended load. The sediment transport efficiency coefficient has been affected by the ratio of the flow depth to the mean diameter of particles and has been dependent on the shear velocity Reynolds number. So $A^{\ast}$ and $B^{\ast}$ are introduced to compensate for the uncertainties such as bed materials, sediment transport, and flow velocity distribution, and the coefficient of bedload ratio has been presented. For the sediment load data in experimental channels and rivers, A* was 3.1. The dominant variables of $B^{\ast}$ were $u_*d_m/{\nu}$ in the gravel-bed and h/dm in the sand-bed. When $B^{\ast}$ the is the same, in the experimental channels the coefficient of bedload ratio was affected by the bed forms, but in the rivers it was of little difference between the gravel-bed and sand-bed.