• Journal of the Korean Society for Heat Treatment
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• v.8 no.4
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• pp.245-254
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• 1995

The purpose of this study was to examine the effects of low melting point phase(LMPP) on mechanical properties in the Al-Cu-Li-X(In, Be) alloys. This study was performed by the differential scanning calorimetry(DSC), the transmission electron microscope(TEM), hardness test, tensile test and notch tensile test. The shape of LMPP in the specimens homogenized at $570^{\circ}C$ was film type due to remelting at grain boundary during homogenization. Low melting point phases had no effects on mechanical properties in the aging treated materials, because the density of LMPPs was low. Mechanical properties of the aging treated materials were affected by the density of matrix precipitation phases and grain sizes. For the In or In, Be added Al-Cu-Li alloys, the optimum solution treatment temperature was $550^{\circ}C$. The strength of Al-Cu-Li-In-Be $T_6$ treated alloy was higher than that of 2090-$T_8$ alloy.

• Journal of Life Science
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• v.32 no.3
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• pp.210-221
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• 2022

This study investigated the mechanisms underlying the anti-cancer effects of non-steroidal anti-inflammatory drugs (NSAIDs) in human cancer cells in combination with either N-[N-(3, 5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT), a γ-secretase inhibitor, or MHY2245, a new synthetic sirtuin 1 inhibitor. The results showed both DAPT and MHY2245 as novel chemosensitizers of human colon cancer KM12 and human hepatocellular carcinoma SNU475 cells to NSAIDs involving celecoxib and 2, 5-dimethyl celecoxib. The NSAID-induced cytotoxicity of these cells was significantly increased by DAPT and MHY2245 in a cyclooxygenase-2 independent manner. In addition, DAPT and MHY2245 reduced levels of p62, Notch1 intracellular domain, and multiple cancer stemness (CS)-related markers including Notch1, CD44, CD133, octamer-binding transcription factor 4, mutated p53 and c-Myc. However, the level of activating transcription factor 4 (ATF4) was enhanced, probably indicating the down-regulation of multiple CS-related markers by DAPT or MHY2245-mediated autophagy induction. Moreover, the NSAID-mediated reduction of p62/nuclear factor erythroid-derived 2-like 2 and CS-related marker proteins and the up-regulation of C/EBP homologous protein (CHOP)/ATF4 were accelerated by DAPT and MHY2245. As such, the combination of NSAID and either DAPT or MHY2245 resulted in higher cytotoxicity than NSAID alone by accelerating the down-regulation of multiple CS-related markers and PARP activation, indicating that both inhibitors promote NSAID-mediated autophagic cell death, possibly through the CHOP/ATF4 pathway. In conclusion, either combination strategy may be useful for the effective treatment of human cancer cells expressing CS-related markers.

• Proceedings of the Korea Concrete Institute Conference
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• 1999.04a
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• pp.727-732
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• 1999

In this research, we made an experiment on the 10 specimen beams that we made. The specimen beams consist of 4 steel plate strengthening beams and 5 carbon fiber sheet strengthening beams. We applied the methods of notch, rounding off a edge, anchor bolt and side shear strengening to the steel plate and for the case of carbon fiber sheet, we applied the methods of anchor bolt, line anchor and shear strengthening. After all the cases were applied, the beams was measured and analyzed about the behavior property of strengthened beams, th ability of strengthening method, the relation between load and the shape of failure, the crack load, the yield load, the shape of crack pattern, the increasing rate from yield load and maximum load and the strain of rebar. All the strengthening methods resulted in almost same value until the yield load, and it wasn't quite different from the theoretical value. In comparison with existing method, the SER, SEAS for the steel plate and the CEA, CESS, CCESS for carbon fiber sheet showed the increasement of ductility with big displacement.

• Journal of the Korean Society for Heat Treatment
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• v.7 no.3
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• pp.199-205
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• 1994

The fracture characteristics and tool life of ceramics and WC, CBN cutting tool when turning heat treated steel STD11($H_RC$ 60) were investigated experimentally to clarify the machinability and optimum tool materials in cutting of difficult-to-cut material with high hardness. Forthermore, the behaviors of the tool wear and failure were examined with regard to cutting force. The hardened steel wore the cutting tool edge rapidily and increased the cutting forces, especially radial force. The tool was worn by the abrasive action. Flank Weat of $Al_2O_3-TiC$ ceramic and WC tool become relatively large and CBN & $Al_2O_3$, ceramic tool had a long life among the tool materials tested. The tool fracture patterns were just like minor cutting wear, flank wear, crater wear, notch wear, chipping. Flank wear rate was accelerated by occurrence of chipping. During the proceeding of machining, it was possible to foresee the catastrophic fracture of tool by abrupt increase of radial force.

• Journal of the Society of Naval Architects of Korea
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• v.39 no.3
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• pp.81-88
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• 2002

The root joint in the welding structures are apt to failure by the stress concentration which is occurred by the external force. Therefore, in the safety and reliability of structure, the complete penetration joint welding which are obtained by the groove welding with edge preparation is generally required. Nevertheless, fillet T-joint welding without edge preparation is often carried out in the fields to reduce working time and consumption of welding electrode, however, this process is likely to produce inadequate joint penetration such as root gap. In this paper, the focus of research is to investigate distribution of welding residual stresses in the plate(or flange) and web of T-joint weld, and especially in the near of root gap notch that is due to incomplete joint penetration. For the analysis, we have chosen model of T-joint weld in the cases of single and multi-pass welding with submerged arc welding and analyzed model by using finite element programs considering the heat conduction and thermal elasto-plastic theory.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.22 no.2
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• pp.416-427
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• 1998

Unidirectional commingled-yarn-based carbon fiber(CF)/polyamide(PA) 6 composite was fabricated under molding pressures of 0.4, 0.6 and 1.0 MPa to study its flexural deformation and fracture behavior. Fiber/matrix interfacial bonding area became larger with an increase of molding pressure from 0.4 to 0.6 MPa. For molding pressures .geq. 0.6 MPa, good flexural performance of similar magnitudes was attained. For the fracture test, four kinds of notch direction were adopted : edgewise notches parallel (L) and transverse (T) to the major direction of fiber bundles, and flatwise notches parallel(ZL) and perpendicular(ZT) to this direction. Nominal bend strength for L and ZL specimens exhibited high sensitivity to notching. ZL specimens revealed the lowest values of the critical stress intensity factor $K_c$ which was slightly superior to those of unfilled PA6 matrix. Enlargement of the compression area for T specimens was analyzed by means of the rigidity reduction resulting from the fracture occurrence.

• Journal of Welding and Joining
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• v.3 no.2
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• pp.42-51
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• 1985

The dynamic fracture toughness, fracture characteristics, impact tension and tensile properties of Al-Mg-Si T5 alloy and Al-Zn-Mg T6 alloy respectively welded with filler metal of Alcan 4043 were investigated. The dynamic fracture toughness values were obtained rapidly and simply for the specimen of small size by using instrumented Chirpy impact testing machine. the testing temperatures of the specimen were a range of room temperature and-196.deg. C. The results obtained in this experiment are summarized as follows. With decreasing the testing temperatures, dynamic tensile stress and fracture load were increased, on the other hand the deflection and impact value showed decreasing tendency in order of base metal>HAZ>weld. Changes of total absorbed energy were more influenced by the crack propagation energy than the crack initiation energy. At the low temperatures, the unstable rapid fracture representing the crack propagation appeared for the specimens of Charpy press side notched in Al-Zn-Mg alloy, but it was difficult to obtain the unstable rapid fracture in Al-Mg-Si alloy. Because of the development of plastic zone at the notch root, it was difficult to obtain thevalid $K_{1d}$ value in Al-Mg-Si alloy. Therefore the fatigue cracked specimens were effective in both Al-Mg-Si and Al-Zn-Mg alloys. With decreasing the impact testing temperatures, specimens underwent a transition from dimple-type transgranular fracture to lamella surface-type intergranular fracture because of the precipitate at the grain boundaries, impurities and crystal structure of the precipitates.s.

• Journal of Advanced Marine Engineering and Technology
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• v.18 no.3
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• pp.52-62
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• 1994

기계나 구조물 파괴의 대부분은 노치부를 기점으로 하여 발생하기 때문에 첨단복합재료를 노지부 재로서 안전하면서도 경제적으로 사용하기 위해서는 각종 조건하에 있어서 강도특성을 명확히 하는 것은 대단히 중요하다. 본 연구에서는 노치를 갖는 복합재료를 이용하여 각종조건하에서 강도특성평가실험을 행하였으 며, 얻어진 결과를 종합하면 다음과 같다. (1) 첨단복합재료 노치재는 試驗片의 幾可學的 形狀과는 관계없이 노치반경 p만에 의해 결정되는 최대탄성응력 $\sigma_{max}$일정의 條件下에서 破t짧된다. (2) 破斷時 최소단면에서의 공칭응력 $\sigma_{c}$와 응력집중계수 $K_{t}$와의 관계에 있어서,$\sigma_{c}$의 값이 $K_{t}$의 증대와 더불어 떨어지고 있는 부분과, $K_{t}$와 관계없이 거의 일정하게 되고 있는 부분으로 나누어지는 現象은 노치재의 回轉굽힘 또는 인장압축파열에서 보여지는 현상과 外觀上 對應하고 있다. 즉, 정적파괴와 피로파괴는 파괴의 양상이 비슷하다 (3) PEN수지단체의 경우, 피로균열발생은 점발생적 피로균열이 최대탄성응력에 의해 지배되며, 노치에 만감하며,균열전파수명은전수명에 비해 상당히 짧다. (4) 단탄소섬유강화복합재료의 경우, 피로균열은 섬유端에 응력이 집중하기 때문에 일반적으로 섬유端에서 아주 빠른 시기에 발생하지만, 섬유가 피로균열진전에 대해 방해물로 작용하기때문에 아주 천천히 전파한다. (5) 短탄소鐵維는 피로균열발생에 대해서는 負의 강화작용 전수명의 극히 초기단계에 피로균열 발생을, 피로균열전파에 대해서는 正의 강화작용을 한다. (6) 단탄소섬유를 PEN에 강화함으로 인해 정적강도 보다 피로강도에 더 큰 강화효과를 초래했으며, 선형노치역학의 개녀은 첨단 복합재료의 강도평가에 대단히 유효했다.

• Progress in Superconductivity
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• v.7 no.1
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• pp.46-51
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• 2005

We have developed control electronics to operate flux-locked loop (FLL), and analog signal filters to process FLL outputs for 64-channel Double Relaxation Oscillation SQUID (DROS) magnetocardiography (MCG) system. Control electronics consisting of a preamplifier, an integrator, and a feedback, is compact and low-cost due to larger swing voltage and flux-to-voltage transfer coefficients of DROS than those of dc SQUIDs. Analog signal filter (ASF) serially chained with a high-pass filter having a cut-off frequency of 0.1 Hz, an amplifier having a gain of 100, a low-pass filter of 100 Hz, and a notch filter of 60 Hz makes FLL output suitable for MCG. The noise of a preamplifier in FLL control electronics is $7\;nV/{\surd}\;Hz$ at 1 Hz, $1.5\;nV/{\surd}\;Hz$ at 100 Hz that contributes $6\;fT/{\surd}\;Hz$ at 1 Hz, $1.3\;fT/{\surd}\;Hz$ at 100 Hz in readout electronics, and the noise of ASF electronics is $150\;{\mu}V/{\surd}\;Hz$ equivalent to $0.13\;fT/{\surd}\;Hz$ within the range of $1{\sim}100\;Hz$. When DROSs are connected to readout electronics inside a magnetically shielded room, the noise of 64-channel DROS system is $10\;fT/{\surd}\;Hz$ at 1 Hz, $5\;fT/{\surd}\;Hz$ at 100 Hz on the average, low enough to measure human MCG.

• Journal of Advanced Marine Engineering and Technology
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• v.10 no.1
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• pp.65-73
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• 1986

Surface fatigue crack propagation tests by plane bending fatigue were conducted on the welding specimens of an aluminium alloy, A5083-0, having an edge through thickness notch to study the fatigue crack growth characteristics. Moreover, the experiments were performed in order to clarify the fatigue crack initiation and growth. The properties of fatigue crack growth were quantitatively inspected in welded metal, heat-affected zone and base metal of the welding specimens. The main results obtained are summarized as follows: 1. It is found that the hardness distributions of A5083-0 aluminium alloy weldments are quite different with those of steel material weldments, so that the hardness distribution becomes lower in the following order: base metal, heat-affected zone and weld metal. 2. It is observed that the grain size of this specimen weldment appears to be almost equal to the base metal, when TIC welding method is adopted. 3. In a surface fatigue crack initiation and growth, the fatigue crack does not begin by opening-closing mechanism until hardening is saturated at the crack tip. 4. The fatigue crack growth characteristics of A5083-0 alluminium alloy weldments can be concluded.$${\frac{da}{dn}}=C({\Delta}K)^n=3.8{\times}10^{-9}{({\frac}{1}{2}{\Delta}S_t{\sqrt{{\pi}a}})}^{2.4}$$