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Effects of Low Calorie Diet and Platycodon Grandiflorum Extract on Fatty Acid Binding Protein Expression in Rats with Diet-induced Obesity

  • Park, Yoon-Shin;Cha, Min-Ho;Yoon, Yoo-Sik;Ahn, Hong-Seok
    • Nutritional Sciences
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    • 제8권1호
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    • pp.3-9
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    • 2005
  • Obesity can be defined as a metabolic disease due to an increased fat accumulation in the body caused by an imbalance of calorie intake and output The prevalence of obesity has increased substantially over the past 2-3 decades in developed and developing countries. The health impact of weight gain is so marked that obesity has now been classified as a major global public health problem In order to investigate the effect of diet conversion and oral administration of Platycodon grandiflorum extracts on the treatment of obesity, male Spraque-Dawley rats were divided into four groups: a group converted to normal diet (Control group), a group maintained high fat (30%) diet (H), and two groups with Platycodon grandiflorum extract added to the previously mentioned two groups. All animals were fed high fat diet for 7 weeks to induce the obesity. Then they were divided as mentioned above. Animals were fed experimental diet and Platycodon grandiflorum extract (150 mg/ml/rat/day) for 7 weeks. Body weight, adipose tissue weight (subcutaneous, epididymal, peritoneal fat pads) and serum lipids (total cholesterol and triglyceride) showed some differences among groups. The Platycodon grandiflorum feeding markedly decreased both body weight and adipose tissue weight in control group compared to H, high fat diet maintaining, group. Platycodon grandiflorum extracts significantly decreased the concentrations of serum lipids compared to H group. Fat cell numbers and sizes were significantly reduced in the oriental medicinal herb extract administrated group. Increased fatty acid binding protein (FABP) expression in high fat diet group was decreased by the dietary conversion to normal diet and the oral administration of Platycodon glandiflorum extracts. In contrast, there was no significant effect on FABP expression in the high fat maintenance group. In this study, the conversion from high fat diet to low fat or normal diet had a beneficial effect on body weight loss and serum lipid profiles. Dietary Platycodon glandiflorum extracts had an additive beneficial effect on the prevention and treatment of obesity.

Body image distortion in fifth and sixth grade students may lead to stress, depression, and undesirable dieting behavior

  • Cho, Jin-Hee;Han, Sung-Nim;Kim, Jung-Hee;Lee, Hong-Mie
    • Nutrition Research and Practice
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    • 제6권2호
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    • pp.175-181
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    • 2012
  • The widespread pursuit of a thin physique may have a detrimental impact on the wellbeing of preadolescents. The influence of body image distortions on the lifestyles, dieting behaviors, and psychological factors was investigated in 631 fifth and sixth grade children in Kyeonggi-do, Korea. Children were classified into three weight groups (underweight, normal, and overweight) and three perception groups (underestimation, normal, and overestimation). Necessary information was obtained by questionnaire, and each subject's weight status was determined by the Rohrer index calculated from the annual measurement records, which were obtained from the school. According to their current weights, 57.4% of children were normal and 32.2% were overweight or obese, 16.6% of the children overestimated their body weight, and 55.2% had an undistorted body image. Overweight children had desirable lifestyles and dietary habits and presented reasonable weight control behaviors. Compared to those without distortion, the overestimated group had greater interest in weight control ($P$ = 0.003) and dissatisfaction with their body weights ($P$ = 0.011), presented unhealthy reasons to lose weight ($P$ = 0.026), and had higher scores for "feeling sad when comparing own body with others" ($P$ = 0.000) and for "easily getting annoyed and tired" ($P$ = 0.037), even though they had similar obesity indices. More subjects from the overestimation group ($P$ = 0.006) chose drama/movies as their favorite TV programs, suggesting a possible role for the media in body image distortion. These findings suggest that body image distortion can lead preadolescents to develop stress about obesity and unhealthy dieting practices, despite similar obesity indices to those without distorted body images. These results emphasize the importance of having an undistorted body image.

중학교 여학생의 비만도에 따른 식습관 및 신체활동 (Eating Patterns and Physical Activities according to Obesity of Female Middle School Students)

  • 한애경;윤현경;조윤희;박정모;김미원
    • 동서간호학연구지
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    • 제18권2호
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    • pp.120-128
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    • 2012
  • Purpose: The purpose of this study was to analyse eating patterns and physical activities according to obesity of female middle school students in Korea. Methods: The 2010 Korea Youth Risk Behavior Survey (KYRBS) data was used for analysis. The subjects of this study were 11,996 female middle school students (10,118 normal weight and 1,778 overweight). The data were analyzed using descriptive analysis, independent t-test, and ${\chi}^2$-test. Results: The findings of this study Indicated that 52.1% of the normal weight group did efforts to lose weight, whereas 60.1% of the overweight groups did. The most common way of reducing body weight was 'reducing food intake', followed by 'regular exercise', 'taking diet supplements' and 'fasting'. Among the entire groups of respondents, 54.6% did not receive dietary education at school over the past year. In addition, 18.8% in normal weight group and 17.0% in overweight group had never receive physical education at school over the past year. Conclusion: The health provider should enhance the school based dietary education and physical education programs for the promotion of adolescents' health status and healthy behaviors.

케톤식이로 발생한 체중감소 및 내당능장애에 침치료 효과 (Effects of Acupuncture Treatment on Weight Loss and Glucose Intolerance Induced by a Ketogenic Diet)

  • 고희재;김동주;김승남
    • Korean Journal of Acupuncture
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    • 제36권4호
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    • pp.274-280
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    • 2019
  • Objectives : This preliminary study investigated the effect of acupuncture treatment on short-term ketogenic diet-induced weight loss and glucose intolerance in mice. Methods : Six-week old male C57BL/6J mice were randomly assigned to 3 groups: normal, KD, and KD+ACU. All the mice except normal group were fed with ketogenic diet formula for 7 weeks and mice in KD+ACU group received acupuncture treatment three times a week. Body weights were measured three times a week, and glucose level was measured on week 1,3,5, and 7. Ketone level was measured on week 3,5, and 7. Results : Ketogenic diet showed short-term weight loss effect, however, acupuncture treatment did not affect on the weight loss. Ketone level was increased in KD fed mice compared to normal diet fed mice and the level was decreased in KD+ACU group on week 3. However, the change was not significantly different compared to KD group on week 7. Glucose intolerance was improved in KD+ACU group compared to KD group. Conclusions : Acupuncture treatment was effective in relieving glucose intolerance, and the results suggest that combining acupuncture treatment with ketogenic diet may complement each therapeutic intervention by improving glucose intolerance but not effecting on weight loss. This study provides meaningful evidence as a preliminary study of acupuncture treatment on ketogenic diet.

스테로이드 치료 후 회복기의 규칙적인 운동이 어린 쥐의 스테로이드 유발성 위축 Type II 근육에 미치는 영향 (Effect of Regular Exercise during Recovery Period Following Steroid Treatment on the Atrophied Type II Muscles Induced by Steroid in Young Rats)

  • 최명애;신기수;안경주;최정안;이윤경
    • 대한간호학회지
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    • 제32권4호
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    • pp.550-559
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    • 2002
  • This study was conducted to determine whether low intensity regular exercise following dexamethasone treatment could attenuate steroid-induced muscle atrophy. Method: 36 Wistar-rats(90-110g) were divided into six groups: control group(C), dexamethasone treatment group(D), sedentary group after normal sedentary period(C+S), sedentary group after dexamethasone treatment period(D+S), exercise group after normal sedentary period(C+E), and excercise group after dexamethasone treatment period(D+E). D, D+S, and D+E groups received dexamethasone injection(5mg/Kg) for seven days whereas C, C+S, and C+E groups received normal saline injection. Both C+E and D+E groups ran on a treadmill for 60 minutes/day(20minutes/4hours) at 15m/min and a 10$^{\circ}$grade for seven recovery days. Result: Post-weight(body weight before muscle dissection) of D group significantly decreased by 16.03%, and that of D+E group significantly increased by 15.51% compared with pre-weight(body weight before steroid treatment). TypeII muscle(plantaris and gastrocnemius) weights of D group were significantly lower than those of C group. Myofibrillar protein contents of typeII muscles of D group tended to decrease comparing with C group. In D+E groups, body weights and relative weights of typeII muscles(muscle weight(mg)/post-weight(g)) tended to increase comparing with D+S group. Conclusion: It is suggested that steroid- induced muscle atrophy can be ameliorated through low intensity regular exercise after dexamethasone treatment.

정상골밀도이하 중년비만여성환자의 기린다이어트시 골밀도 변화 (Change of Bone Mineral Density after Kirindiet therapy in Middle-Aged Obese Women under Normal Bone Mineral Density)

  • 최영민;심우진;김길수;윤유식;신승우
    • 한방비만학회지
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    • 제5권1호
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    • pp.47-56
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    • 2005
  • Objectives : This study was performed to investigate the change of bone mineral density(BMD) after 1 month Kirindiet therapy including very low calory diet(VLCD) in middle-aged obese women$(65>age{\geqq}40,\;BMI{\geqq}25)$ under normal $BMD(T-score{\leqq}0)$. Methods : We examined body weight, body fat, protein mass and BMD of 13 middle-aged obese women who visited to Kirin Oriental Hospital from Sep. 7. 2004 to Oct. 12. 2005 before and after 1 month Kirindiet therapy. Body weight, body fat and protein mass was checked by Inbody 4.0 and BMD was checked by quantitated computed tomography. Wilcoxon signed rank test was used for analyzing changes of body weight, body fat, protein mass and BMD before and after treatment. Results : Alter 1 month treatment body weight(-4.89Kg, -6.74%, p=0.001), body fat(-3.47Kg, p=0.001) and protein mass(-0.97Kg, p=0.006) was significantly reduced. BMD was significantly increased in all cases(+4.87mg/cc, +4.16%, p=0.001). Though body weight, body fat and protein mass were significantly reduced, BMD was significantly increased(p<0.01). Conclusions : In this study, we can conclude that after 1 month Kirindiet therapy including VLCD, BMD in middle-aged obese women under normal BMD was significantly increased inspite of reduction of body weight, body fat and protein mass.

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광주광역시 유아의 체중별 식행동과 영양지수 (Dietary Behavior and Nutrition Quotient (NQ) Scores According to the Weight Status of Preschool Children in Gwangju Metropolitan City)

  • 한규상;양은주
    • 한국식생활문화학회지
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    • 제36권4호
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    • pp.412-420
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    • 2021
  • This study aimed to assess the association between the weight status and dietary behavior of preschool children. The survey included 412 preschool children aged 2-5 years in 31 childcare facilities in Gwangju. General characteristics of children and their mothers, weight, height, feeding type, complementary feeding, food allergy, and dietary behavior of children based on the Nutrition Quotient for preschoolers (NQ-P) questionnaire were considered. Children were classified into 4 groups by weight status; underweight, normal, overweight, and obese, based on the 2017 Korean National Growth Charts. The percentage of children in the respective groups was 5.3, 70.9, 10.7, 13.1%. Weight status was not related to breast feeding duration nor the starting time of complementary feeding. The NQ-P scores of underweight, normal, overweight, and obese groups were 55.4, 60.0, 60.8, 60.0. Among the three factors covered by the NQ-P, 'balance' and 'environment' scores of the underweight group were lower than that of other groups. Underweight children consumed beans, fish, and white milk less frequently. The 'moderation' scores of the overweight/obese group were lower than those of the normal or obese groups. Obese children more frequently ate processed meat and fast foods. Proper nutrition education is thus needed for not only obese children but also underweight children based on their age, along with their parents, and caregivers.

여대생들의 체중에 대한 인식과 신체 부위별 만족도 (Recognition of Body Weight and Body Part Satisfaction in Female College Students)

  • 김미옥;은종극;장은재
    • 한국식품영양학회지
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    • 제22권2호
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    • pp.205-214
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    • 2009
  • Diet is an important focus in solidifying the fundamentals of health; thus, it is necessary to offer and manage accurate and correct information. This study examined the effects of body part satisfaction and attitude on diet, in female college students, who are known to be very interested in their appearances and tend to have a strong propensity to consume. The data were gathered using questionnaires answered by 101 female college students living in Daegu City, after classifying the women into normal weight and overweight groups, respectively. According to the analyzed results, there were no significant differences in satisfaction by body part between the normal weight and overweight groups, however, both groups were found to be dissatisfied with the following body parts, in the order of: thighs > legs > and hips. The motivation factors for weight control were found to be in order: not having a boyfriend > lacking of confidence > seeing slender entertainment stars, and there were no significant differences between the two groups. Finally, the main reasons for weight control were in order: appearance > health > getting a job. It is anticipated that these results will contribute to preparing systematic solutions to promote healthy diets and body satisfaction in society, and will help bring a desirable change in perceptions about diet.

Synergetic Effect of Minerals Mixture of Potassium Bromide and Nickel Sulphate on the Economic Traits of $CSR_2,\;CSR_4\;and\;CSR_2{\times}CSR_4$ Crossbreed Races of the Silkworm, Bombyx mori L.

  • Kochi S. C.;Kaliwal B. B.
    • International Journal of Industrial Entomology and Biomaterials
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    • 제10권2호
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    • pp.107-117
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    • 2005
  • Oral supplementation of minerals mixture of potassium bromide and nickel sulphate on $CSR_2,\;CSR_4\;and\;CSR_2{\times}CSR_4$ crossbreed races with different concentrations (70, 110 and $160\;{\mu}g/ml$) were fed to the fifth instar larvae. Two of the four normal feeds per day was substituted with treated leaves fed to silkworm at fifth instar larvae. The controls were fed with the leaves sprayed with distilled water and normal leaves. The $CSR_4$ race treated larvae showed a significant increase in silkgland weight, cocooning percentage, female cocoon weight, male cocoon weight, male cocoon shell weight, male cocoon shell ratio, filament length, filament weight, denier, fecundity, number of eggs per ovariole and length of the ovariole when compared with those of the corresponding parameters of the carrier control, whereas in $CSR_2\;and\;CSR_2{\times}CSR_4$ crossbreed races showed a significant increase in larva1 weight and other parameters similar to that of $CSR_4$ race. The results suggested that the silkgland showed good response to minerals mixture of potassium bromide and nickel sulphate only in $CSR_4$ race when compared with those of other two races of the silkworm, B. mori.

자세균형제어 시스템의 개발 (Development of Postural Balance Control System)

  • 양길태;김영호;임송학;장윤희;문무성
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1997년도 추계학술대회
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    • pp.276-279
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    • 1997
  • A simple bio-feedback system was developed to monitor and to analyze patient's postural balance. Two load celIs were used to measure the weight of each side. A specially designed electronic circuit was made to pick up the weight signals and to feed into the data acquisition system. Clinical trials were also made on 20-30 year-old normal subjects and nine hemiplegia patients who had the potential instability in weight bearing. A Microsoft window-based software collected and analyzed the postural balance data. Normal subjects showed only 5% deviations of their body weight. However, hemipegic patients had significant weight shifts toward the healthy limb. With the present system, patients can also exercise their balance and weight bearing. The present system should be of convenience to monitor in real-time and analyze the postural balance control of hemiplegic patients.

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