• 제목/요약/키워드: Normal response

검색결과 2,178건 처리시간 0.029초

Preliminary Study of Neuronal Response to Dose Distribution of Radiation with MR Spectroscopy

  • Ahn, Seung-Do;Yi, Byoung-Young;Lee, Jung-Hee
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 2002년도 제9회 학술 발표회 프로그램과 논문초록
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    • pp.25-26
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    • 2002
  • The goal of radiation therapy is to maximize the tumor dose and to minimize the dose of normal tissue. In order to achieve this goal, the new radiation therapy techniques such as three dimensional conformal therapy or intensity modulated radiation therapy has been developed and tried to clinical application. The relationship between radiation dose and normal tissue response is an interesting subject in the radiation therapy field.(omitted)

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최대운동부하시 정상인과 만성요통환자의 심폐계 반응에 대한 비교연구 (A comparative study on the cardiovascular function response to maximal exercise of chronic low back pain patients and normal group)

  • 엄기매;김건도;황명훈
    • The Journal of Korean Physical Therapy
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    • 제12권3호
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    • pp.379-386
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    • 2000
  • This study is aimed to determine the cardiovascular function response to maximal exercise of chronic low back pain patients(N=13) and normal group(N=13). by using BRUCE PROTOCOL, subjects underwent tredmill exercise test. Their cardiovascular function responses during rest and after maximal exercise were compared The responses were analyzed using t-test for SPSS 7.0 program. The Cardiovascular function variables employed at rest time(Vo2, HR. Vo2/kg, VE, Vco2.) and all out time(Vo2peak. HRpeak, Vo2peak/kg, VEpeak. Vco2peak). Result show that : 1 There was no significant difference in Vo2 between chronic low back pain patients and normal group at rest time. However significant difference in Volpeak was observed after maximal exercise( p<.05). 2. There was no significant difference in HR between chronic low back pain patients and normal group at rest time. No significant difference in HRpeak likewise observed. 3. There was no significant difference in Vo2/kg between chronic low back pain patients and normal group at rest time. However significant difference in Vo2peak/kg was observed after maximal exercise load(p<.05). 4. There was no significance in VE between chronic low bark pain patients and normal group at rest time. However significant difference in VEpeak observed after maximal exercise load(p<.05).

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사업체조사에서의 무응답 편향보정 추정에 관한 연구 (A study on non-response bias adjusted estimation in business survey)

  • 정희영;신기일
    • 응용통계연구
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    • 제33권1호
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    • pp.11-23
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    • 2020
  • 표본조사는 비용과 시간을 절약하면서도 주어진 정확성을 만족하는 통계를 얻을 수 있다. 그러나 최근에는 다수의 무응답 발생으로 인해 조사의 정확성이 크게 떨어지고 있다. 무응답은 다양한 이유로 발생하고 있으나 무응답이 관심변수와 함수 관계가 있는 경우에는 이 정보를 이용하여 무응답을 적절히 처리해야 추정의 정확성이 유지될 수 있다. 최근 Chung과 Shin (2017, 2019), Min과 Shin (2018)은 응답률이 관심변수의 지수 또는 선형함수이고 초모집단모형의 오차가 정규분포를 따를 때 무응답으로 인해 발생한 편향을 제거함으로써 추정의 정확성이 향상되는 것을 확인하였다. 이에 본 연구에서는 사업체조사에서 초모집단모형의 오차가 감마분포 또는 로그-정규분포를 따르는 경우에서의 무응답 편향보정 추정량을 제안하였다. 또한 모의실험을 통하여 제안된 추정량의 우수성을 확인하였다.

한국 중년 남성에서 복부지방 축적이 혈청 지질 및 지단백 농도에 미치는 영향 (Influence of Total Abdominal Fat Accumulation on Serum Lipids and Lipoproteins in Korean middle-aged men)

  • 허갑범;이종호;백인경;안광진;정윤석;김명중;이현철;이영해;이양자
    • Journal of Nutrition and Health
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    • 제26권3호
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    • pp.299-312
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    • 1993
  • Anthropometry, computed tomography(CT) at the umbilical level, nutrient intake, blood pressure, serum levels of lipids and lipoproteins and response of glucose, c-peptide, insulin, and free fatty acid(FFA) during oral glucose tolerance test(OGTT) were estimated on 11 normal-weight controls and 35 overweight and obese middle-agd men. The areas of total abdominal, subcutaneous and visceral were determined by CT scanning technique. Total abdominal fat area correlated the most significantly with the levels of serum lipids, lipoproteins and insulin among several obese indices. Compared with normal-weight controls, overweight and obese men with abdominal fat lower than 29000$\textrm{mm}^2$ showed an increase in waist-hip ratio, areas of total abdominal(35%), visceral and subcutaneous fat and C-peptide response area during OGTT, though age, percent ideal body weight, body mass index, % body fat, and all biochemical indices except C-peptide response area were not different between two groups. Overweight and obese men with abdominal fat greater than 29000$\textrm{mm}^2$ showed a higher values in total abdominal fat(85%), serum levels of triglyceride, total-and LDL-cholesterol, the ratio of LDL-to HDL-cholesterol, and response areas of FFA, insulin and C-peptide during OGTT than normal-weight controls. Overweight and obese men with great abdominal fat showed an increase in alcohol ingestion and percent calorie intake per total energy expenditure, compared with normal-weight controls. Our results indicate that obesity and a certain level of total abdominal fat accumulation is required to observe abnormal levels of serum lipids, lipoproteins and insulin in Korean middle-aged men. In addition, increased alcohol and calorie intake and decreased physical activity could partly explain total abdominal fat accumulation in men.

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Molecular characterization and expression of suppressor of cytokine signaling (SOCS) 1, 2 and 3 under acute hypoxia and reoxygenation in pufferfish, Takifugu fasciatus

  • Wang, Dan;Wen, Xin;Zhang, Xinyu;Hu, Yadong;Li, Xinru;Zhu, Wenxu;Wang, Tao;Yin, Shaowu
    • Genes and Genomics
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    • 제40권11호
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    • pp.1225-1235
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    • 2018
  • Hypoxia seriously affects the innate immune system of fish. However, the roles of suppressor of cytokine signaling (SOCS), pivotal anti-inflammatory genes, in response to hypoxia/reoxygenation remain largely unexplored. The primary objective of this study was to elucidate the function of SOCS genes under acute hypoxia and reoxygenation in pufferfish (Takifugu fasciatus). In the present study, SOCS1, 2 and 3 were identified in T. fasciatus referred to as TfSOCS1, 2 and 3. Then, qRT-PCR and western blot analysis were employed to assess their expressions at both the mRNA and protein levels. Tissue distribution demonstrated that the three SOCS genes were predominantly distributed in gill, brain and liver. Under hypoxia challenge ($1.63{\pm}0.2mg/L$ DO for 2, 4, 6 and 8 h), the expressions of TfSOCS1 and 3 in brain and liver at the mRNA and protein levels were significantly decreased, while their expressions showed an opposite trend in gill. Different from the expressions of TfSOCS1 and 3, the expression of TfSOCS2 was inhibited in gill, along with its increased expression in brain and liver. After normoxic recovery ($7.0{\pm}0.3mg/L$ of DO for 4 and 12 h), most of TfSOCS genes were significantly altered at R4 (reoxygenation for 4 h) and returned to the normal level at R12 (reoxygenation for 12 h). SOCS genes played vital roles in response to hypoxia/reoxygenation challenge. Our findings greatly strengthened the relation between innate immune and hypoxia stress in T. fasciatus.

자기공명영상사진 상에 나타난 측두하악관절원판의 형태 및 그에 따른 치료 효과의 분석 (Configuration of Temporomandibular Joint Articular Disc in Magnetic Resonance Images and its Relationship to Treatment Response of Anterior Disc Displacement Without Reduction)

  • 권진학;기우천;최재갑
    • Journal of Oral Medicine and Pain
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    • 제25권1호
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    • pp.73-85
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    • 2000
  • The purposes of the study were (1) to see if there are various types of disc configuration in normal temporomandibular joint and, if so, (2) to examine whether a specific type of disc configuration is susceptible to disc displacement, and (3) to see if a specific type of disc configuration and position is related to early relief of clinical symptoms from the anterior disc displacement without reduction to conservative treatment. From the magnetic resonance (MR) images taken for the patients with symptoms of temporomandibular disorders, 235 images as normal joint group, 255 images as anterior disc displacement with reduction group, and 249 images as anterior disc displacement without reduction group were selected, After the TMJ image was scanned and processed with Photoshop program, the disc configuration was determined, The incidence of various types of disc configuration was analyzed according to age, sex, diagnostic group, and the promptness of symptom relief. The disc position was also examined in relation to the promptness of symptom relief. The results were as follows : 1. In the normal joint group, biconcave type appeared most frequently and reversed, biplanar type in order, Posterior band enlarged and folded type didn't appear at all. On the other hand, in the anterior disc displacement without reduction group, folded type appeared most frequently and also posterior band enlarged type were found often. 2. There were statistically significant differences between sex and configuration of disc in the normal joint group and no statistically significant differences in the anterior disc displacement with reduction group and anterior disc displacement without reduction group, 3. There were no statistically significant differences between age and configuration of disc in the normal, anterior disc displacement with reduction group and anterior disc displacement without reduction group. 4. In anterior disc displacement without reduction group, rapid response was observed in biconcave and reversed type and delayed response was observed in folded type.

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부하변동에 의한 지중유효열전도도와 보어홀 전열저항 해석 (Analysis of Effective Soil Thermal Conductivities and Borehole Thermal Resistances with a Power Supply Regulation)

  • 노정근;연광석;송헌
    • 한국태양에너지학회 논문집
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    • 제31권4호
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    • pp.80-86
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    • 2011
  • Investigation of the effective soil thermal conductivity(k) is the first step in designing the ground loop heat exchanger(borehole) of a geothermal heat pump system. Another important factor is the borehole thermal resistance($R_b$). Thermal response tests offer a good method to determine the ground thermal properties for the total heat transport in the ground. This is done by supplying a constant heat power into a borehole heat exchanger. There are two methods to supply a constant heat power. One is to employ the electricity provided by Korea Electric Power Corporation(KEPCO). The other is to use electricity generated by a generator. In this study, the power supply regulation was found to reduce when the electricity generated by the generator was used. This is because the generator evaluated with the power supply characteristically reduces the power supply regulation between an overload and a complex using. But it sometimes occurs a power supply regulation in In-situ thermal response test. In this case getting of k,$R_b$ requires delay times and restored normal state. However, the effect of the delay times and restored normal state on the soil thermal conductivity and borehole thermal resistance is very small. Therefore it is possible to use a generally accepted delay times and restored normal state in the analysis. In this work, it is also shown that an acceptable range of ${\Delta}k$, ${\Delta}R_b$ for normal state and regulation state might be approximately 0.01-0.16W/m k, and -0.004-0.007m K/W, respectively. Thus, restored normal state of power supply regulation is valuable to recommend.

생체전기자율반응 측정기를 이용한 조기난소부전증 환자의 피부저항변이도 연구 (1, 2, 3 상한 중심으로) (A Study of Skin Resistance Variability of POF Patients by Autonomic Bioelectric Response Recorder (Centering around 1-3 Parts))

  • 최은미;강명자;위효선
    • 대한한방부인과학회지
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    • 제19권3호
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    • pp.247-256
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    • 2006
  • Purpose : To research the Skin Resistance Variability(SRV) of premature ovarian failure(POF) patients by Autonomic Bioelectric Response Recorder(ABR-2000 system, Meridian, Korea) and report the specific results in SRV of POF patients. Methods : We measured SRV of 17 POF Patients who came to Conmaul Oriental Medical Hospital during August 2005 ${\sim}$ July 2006 by ABR-2000 system. We analyzed the results which height of graph Part was converted into 0${\sim}$10, and the readings of Low/Normal/High. Results : The mean value of graph height on each(1, 2, 3) part is lower than normal range(4-6) in POF patients. The distribution ratio of Low/Normal/High on each(1, 2, 3) part shows that there are much more Low proportion in POF patients. Conclusion : The low graph height of POF patients on 1, 2, 3 part means that conductivity & capacitance of POF patients is low, especially on head.

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일반강도 및 고강도 재료를 사용한 보-기둥 접합부의 지진응답 (Seismic Response of Exterior Beam-Column Subassemblies Using Normal and High-Strength Materials)

  • 장극관;서대원
    • 한국지진공학회논문집
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    • 제3권4호
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    • pp.83-94
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    • 1999
  • 고강도 콘크리트는 부재의 내력증가 뿐만아니라 내구성을 증대시키기 때문에 널리 사용되고 있다 그러나 고강도 철근콘크리트 보-기둥 접합부의 구조성능에 관한 연구자료는 충분하지 않은 실정이며 현행규준 또는 일반강도 콘크리트의 실험에 근거하고 있다 따라서 본 연구에서는 일반강도 $(f_c'=240kg/\textrm{cm}^2) 및 고강도(f_c'=700kg/\textrm{cm}^2)$ 콘크리트를 사용하여 실제의 중진지역 30층 실제구조물의 2/3크기를 축소한 보와 기둥 슬래브로 구성된 네 개의 부분구조체를 제작하여 유사정적실험을 통한 구조거동과 파괴형태를 조사하고 전단내력에 대한 현행규준과 비교 검토하였다.

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Bilateral Congenital Deafness in a White Bull Terrier; Brainstem Auditory Evoked Response Findings

  • Kang, Byeong-Teck;Lee, So-Young;Jung, Dong-In;Kim, Hyung-Joong;Woo, Eung-Je;Park, Hee-Myung
    • 한국임상수의학회지
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    • 제25권6호
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    • pp.506-509
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    • 2008
  • A 2-month-old, intact female white Bull Terrier presented because of suspected deafness. The coat color was predominantly white and the iris color, of both eyes, was brown. The dog did not respond to the owner's voice when the sound stimuli were presented outside of the visual field; however, the dog responded to visual gestures. The other physical, neurological, otoscopic, radiographic, and blood examinations were unremarkable. To assess the apparent deafness, brainstem auditory evoked responses (BAER) were recorded and analyzed in the dog with suspected deafness as well as a normal littermate. The response in the normal littermate consisted of a series of five wave peaks (I-V) with decreased amplitude and prolonged latency as the stimulus intensity decreased. The BAER from the dog suspected of deafness appeared as a flat line and did not reveal identifiable peaks that corresponded to those found in the normal littermate. Thus, congenital, sensorineural and bilateral deafness was confirmed by the BAER.