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A Study on Effectiveness of Weight in Analytical Positioning of Oblique Photography (경사사진(傾斜寫眞)의 해석적(解析的) 위치결정(位置決定)에 있어서 경중율(輕重率) 적용에 관한 연구(硏究))

  • Yang, In Tae;Kwon, Hyon;Yeu, Bock Mo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.4 no.2
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    • pp.143-150
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    • 1984
  • This paper is a study on effectiveness of weight in analytical positioning of oblique photography. Oblique photographies are more economical than normal photographies as it has a larger ground coverage and as it can be applied in situations where objects of interest are difficult to be approached. But the comparatively complex methods involved, present a problem in obtaining the desired results. In view of this fact, analytical rectification was applied in normalizing the oblique photographs. As oblique photographies are extensively used in slops and mountainous regions, a number of difficulties are encountered during the control surveying. The photocoordinates of the oblique photographs, taken at $30^{\circ}$, were weighted during rectification. They were weighted as inversely proportionate to the derived formular of ${\gamma}_y=f{\cdot}tan{\frac{\theta}{2}}+y_a$, the distance of each point from the isocenter along the Y axis. By applying the weights, coordinates errors conld be reduced and the error difference between oblique and normal photographs could be reduced upto 53.2%.

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Promoter Methylation Status of DNA Repair Gene (hMLH1) in Gastric Carcinoma Patients of the Kashmir Valley

  • Wani, Majid;Afroze, Dil;Makhdoomi, Muzamil;Hamid, Iqra;Wani, Bilal;Bhat, Gulzar;Wani, Rauf;Wani, Khursheed
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.4177-4181
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    • 2012
  • Cancer is a multi-factorial disease and variation in genetic susceptibility, due to inherited differences in the capacity to repair mismatches in the genome, is an important factor in the development of gastric cancer (GC), for example. Epigenetic changes, including aberrant methylation of 5/CpG islands in the promoter regions of mismatch repair (MMR) genes like hMLH1, have been implicated in the development of various types of GC. In the present study we evaluated the role of hMLH1 promoter hypermethylation in Kashmiri GC patients and controls, and assessed correlations with various dietary and lifestyle factors. The study included 70 GC patients (56 males and 14 females; age ($mean{\pm}S.D$) $50{\pm}11.4$ years). Distinction between methylated and unmethylated was achieved with MS-PCR and DNA band patterns. The Chi-square test was applied to assess the risk due to promoter hypermethylation. We found a strikingly high frequency of promoter hypermethylation in GC cases than in normal samples (72.9% (51/70) in GC cases vs 20% (14/70) in normal samples (p=0.0001).We also observed a statistically significant association between methylated hMLH1 gene promoter and smoking, consumption of sundried vegetables and hot salted tea with the risk of GC. This study revealed that hMLH1 hypermethylation is strongly associated with GC and suggested roles for epigenetic changes in stomach cancer causation in the Kashmir valley.

Blood glucose change after surgical administration of insulin formula into rat intestinal regions (Rat의 intestine 각 부위에 수술적으로 투여 된 insulin 제제에 의한 혈당 변화)

  • Kim, Nam Joong;Kim, Myung-Cheol
    • Korean Journal of Veterinary Research
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    • v.42 no.2
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    • pp.283-288
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    • 2002
  • The present study was carried out to examine the effect of insulin formula on blood glucose change in normal Sprague-Dawley male rats. Also, this study was performed to investigate the feasibility of oral insulin formula development. To administrate the insulin formula into intestine, the surgical technique, celiotomy, was performed in rats. Insulin formula was administrated at a dose of 24.5 IU/kg via duodenum, ileum, and colon of the rats, and the blood glucose level was measured. For the comparison, the vehicle without insulin was administrated into ileum via celiotomy. Also, this insulin formula was administrated into rats orally using sonde and the same parameter was treasured. The bloods of all groups were collected from tail veins using syringes at given time interval. Orally administrated group did not show the change of blood glucose level and control group slightly show the change of blood glucose level at 1 hour after celiotomy. All intestinally administrated groups showed the change of blood glucose level. Among the tested groups, ileac administration group and colonic administration group showed the significant change of blood glucose level. Particularly, ileac administration group showed the lowest blood glucose level. To calculate the bioavailability of intestinal and oral administration, insulin solution was injected subcutaneosly, common insulin injection route, into another normal rats. The bioavailability of ileac group was 8.3% when compared with subcutaneous injection, duodenal group was 1.8%, colonic group was 4.2%, and oral group was 0.2%, respectively.

Anomalous Trajectory Detection in Surveillance Systems Using Pedestrian and Surrounding Information

  • Doan, Trung Nghia;Kim, Sunwoong;Vo, Le Cuong;Lee, Hyuk-Jae
    • IEIE Transactions on Smart Processing and Computing
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    • v.5 no.4
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    • pp.256-266
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    • 2016
  • Concurrently detected and annotated abnormal events can have a significant impact on surveillance systems. By considering the specific domain of pedestrian trajectories, this paper presents two main contributions. First, as introduced in much of the work on trajectory-based anomaly detection in the literature, only information about pedestrian paths, such as direction and speed, is considered. Differing from previous work, this paper proposes a framework that deals with additional types of trajectory-based anomalies. These abnormal events take places when a person enters prohibited areas. Those restricted regions are constructed by an online learning algorithm that uses surrounding information, including detected pedestrians and background scenes. Second, a simple data-boosting technique is introduced to overcome a lack of training data; such a problem particularly challenges all previous work, owing to the significantly low frequency of abnormal events. This technique only requires normal trajectories and fundamental information about scenes to increase the amount of training data for both normal and abnormal trajectories. With the increased amount of training data, the conventional abnormal trajectory classifier is able to achieve better prediction accuracy without falling into the over-fitting problem caused by complex learning models. Finally, the proposed framework (which annotates tracks that enter prohibited areas) and a conventional abnormal trajectory detector (using the data-boosting technique) are integrated to form a united detector. Such a detector deals with different types of anomalous trajectories in a hierarchical order. The experimental results show that all proposed detectors can effectively detect anomalous trajectories in the test phase.

Regional Analysis of Particulate Matter Concentration Risk in South Korea (국내 지역별 미세먼지 농도 리스크 분석)

  • Oh, Jang Wook;Lim, Tea Jin
    • Journal of the Korean Society of Safety
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    • v.32 no.5
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    • pp.157-167
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    • 2017
  • Millions of People die every year from diseases caused by exposure to outdoor air pollution. Especially, one of the most severe types of air pollution is fine particulate matter (PM10, PM2.5). South Korea also has been suffered from severe PM. This paper analyzes regional risks induced by PM10 and PM2.5 that have affected domestic area of Korea during 2014~2016.3Q. We investigated daily maxima of PM10 and PM2.5 data observed on 284 stations in South Korea, and found extremely high outlier. We employed extreme value distributions to fit the PM10 and PM2.5 data, but a single distribution did not fit the data well. For theses reasons, we implemented extreme mixture models such as the generalized Pareto distribution(GPD) with the normal, the gamma, the Weibull and the log-normal, respectively. Next, we divided the whole area into 16 regions and analyzed characteristics of PM risks by developing the FN-curves. Finally, we estimated 1-month, 1-quater, half year, 1-year and 3-years period return levels, respectively. The severity rankings of PM10 and PM2.5 concentration turned out to be different from region to region. The capital area revealed the worst PM risk in all seasons. The reason for high PM risk even in the yellow dust free season (Jun. ~ Sep.) can be inferred from the concentration of factories in this area. Gwangju showed the highest return level of PM2.5, even if the return level of PM10 was relatively low. This phenomenon implies that we should investigate chemical mechanisms for making PM2.5 in the vicinity of Gwangju area. On the other hand, Gyeongbuk and Ulsan exposed relatively high PM10 risk and low PM2.5 risk. This indicates that the management policy of PM risk in the west side should be different from that in the east side. The results of this research may provide insights for managing regional risks induced by PM10 and PM2.5 in South Korea.

Distortion Correction in Magnetic Resonance Images on the Measurement of Muscle Cross-sectional Area (자기공명영상을 이용한 근육 단면적 측정법의 활용을 위한 영상왜곡보정)

  • Hong, Cheol-Pyo;Lee, Dong-Hoon;Park, Ji-Won;Han, Bong-Soo
    • The Journal of Korean Physical Therapy
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    • v.24 no.2
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    • pp.66-72
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    • 2012
  • Purpose: The purpose of this study is to explore the importance of the image distortion correction in the cross sectional area measurement for the iliopsas muscle, tensor fasciae latae muscle, gluteus maximus muscle and the knee extensor muscles, by using (magnetic resonance imaging) MRI. Methods: This study was performed using an open 0.32T MRI system. To estimate the image distortion, T1 images for an AAPM homogeneity/linearity phantom were acquired, and the region in which the maximum geometric distortion was less than or equal to the pixel size (1.6 mm) of the images, it was defined as the distortion correction-free region. The T2 images for a human subject's pelvis and thigh in normal positions were obtained. Then, after the regions of interest in the pelvis and thigh were moved into the distortion correction-free region, T2 images for the pelvis and thigh were scanned with the same imaging parameters used in the previous T2 imaging. The cross-sectional areas were measured in the two T2 images that were obtained in the normal position, and the distortion correction-free region, as well as the area error caused by geometric image distortion was calculated. Results: The geometrical distortion is gradually increased, from the magnet center to the outer region, in axial and coronal plane. The cross-sectional area error of gluteus maximus muscle and the knee extensors was as high as 9.27% and 3.16% in before and after distortion correction, respectively. Conclusion: The cross-sectional area of the muscles that suffered from the geometrical distortion is necessary to correct for the estimation of the intervention.

The effect of photon energy on intensity-modulated radiation therapy (IMRT) plans for prostate cancer

  • Sung, Won-Mo;Park, Jong-Min;Choi, Chang-Heon;Ha, Sung-Whan;Ye, Sung-Joon
    • Radiation Oncology Journal
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    • v.30 no.1
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    • pp.27-35
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    • 2012
  • Purpose: To evaluate the effect of common three photon energies (6-MV, 10-MV, and 15-MV) on intensity-modulated radiation therapy (IMRT) plans to treat prostate cancer patients. Materials and Methods: Twenty patients with prostate cancer treated locally to 81.0 Gy were retrospectively studied. 6-MV, 10-MV, and 15-MV IMRT plans for each patient were generated using suitable planning objectives, dose constraints, and 8-field setting. The plans were analyzed in terms of dose-volume histogram for the target coverage, dose conformity, organs at risk (OAR) sparing, and normal tissue integral dose. Results: Regardless of the energies chosen at the plans, the target coverage, conformity, and homogeneity of the plans were similar. However, there was a significant dose increase in rectal wall and femoral heads for 6-MV compared to those for 10-MV and 15-MV. The $V_{20Gy}$ of rectal wall with 6-MV, 10-MV, and 15-MV were 95.6%, 88.4%, and 89.4% while the mean dose to femoral heads were 31.7, 25.9, and 26.3 Gy, respectively. Integral doses to the normal tissues in higher energy (10-MV and 15-MV) plans were reduced by about 7%. Overall, integral doses in mid and low dose regions in 6-MV plans were increased by up to 13%. Conclusion: In this study, 10-MV prostate IMRT plans showed better OAR sparing and less integral doses than the 6-MV. The biological and clinical significance of this finding remains to be determined afterward, considering neutron dose contribution.

Nucleus Recognition of Uterine Cervical Pap-Smears using Fuzzy Reasoning Rule (퍼지 추론 규칙을 이용한 자궁 경부진 핵 인식)

  • Kim, Kwang-Baek;Song, Doo-Heon
    • Journal of the Korea Society of Computer and Information
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    • v.13 no.3
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    • pp.179-187
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    • 2008
  • In this paper, we apply a set of algorithms to classily normal and cancer nucleus from uterine cervical pap-smear images. First, we use lightening compensation algorithm to restore color images that have defamation through the process of obtaining $1{\times}400$ microscope magnification. Then, we remove the background from images with the histogram distributions of RGB regions. We extract nucleus areas from candidates by applying histogram brightness, Kapur method, and our own 8-direction contour tracing algorithm. Various binarization, cumulative entropy, masking algorithms are used in that process. Then, we are able to recognize normal and cancer nucleus from those areas by using three morphological features - directional information, the size of nucleus, and area ratio - with fuzzy membership functions and deciding rules we devised. The experimental result shows our method has low false recognition rate.

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Pathological Studies on the Esophagogastric Ulcers in Swine (돼지의 위궤양(胃潰瘍)에 관한 병리학적(病理學的) 연구(硏究))

  • Kang, Mun-Il;Rim, Bong-Ho;Lee, Chung-Gil
    • Korean Journal of Veterinary Research
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    • v.22 no.1
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    • pp.53-58
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    • 1982
  • Stomachs from 3,354 fattening pigs were examined at slaughter during the period from September 1980 to August 1981. Pigs of both sexes and $Landrace{\times}Hampshire$ crossbreds were included in the present studies, and they weighed about 60-120kg. Gross pathologic alterations of the stomach were classified as normal, epitnelial change, erosion, ulcer and scar formation. Representative tissue sections were taken from the stomach lesions at random and fixed in 10% buffered formalin. Cut sections were stained with hematoxylin and eosin, and examined histopathologically. The results obtained in the present studies were as follows. 1. In the seasonal prevalence of gastric ulceration, severe ulceration with erosion was shown during the Autumn and Winter, whereas mild ulceration was mainly shown during the Spring and Summer. 2. Of the 3,354 stomachs of the pigs, 20.8% were found to be normal. Of the rest, 40% had epithelial changes, followed by erosion (24.7%), ulcer (13.6%) and scar formation (0.9%), respectively. 3. In the prevalence of ulcers in the different regions of the stomach, the fundic region had the highest rate (61.6%) of ulceration, followed by cardiac (21.7%), esophageal (15.0%) and pyloric region (1.7%). 4. The principal gross changes were severe epithelial changes with keratotic proliferation in the esophageal region, and in the fundic region severe folding of the stomach wall was covered with bloody mucous exudates. 5. Main histopathological changes were inflammatory cell infiltrations in most cases, hemorrhages in acute ulcers and prominent proliferation of granulation tissues in chronic ulcers.

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A constant power and optimal power factor drive of doubly fed induction generator (이중여자 유도발전기의 정출력.최적역률 운전)

  • 이우석
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.14 no.4
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    • pp.31-38
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    • 2000
  • Wide operating range and speed control is needed for wind power generating and a Doubly Fed Induction Generator(DFIG) has good adaptivity for that purpose. This paper deals with the speed, power, and power factor control using the Grid connected DFIG in the super-synchronous speed regions, by controlling frequency and voltage fed to the rotor. Power flow of the DFIG and steady-state algebraic equations of the equivalent circuit are analyzed. The wind turbine speed and constant stator power were controlled by the rotor exciting frequency. For a normal operating region, in which the generator ratings were not exceeded, rotor exciting frequency. For a normal operating region, in which the generator ratings were not exceeded, the rotor current was either less than or equal to the rated value. Accordingly, the optimal power factor can be selected relative to the permissible rated current at the rotor coil which controls the magnitude of the injected rotor voltage to the rotor according to a given rotor frequency. Consequently, it is possible to determine the optimal drive of a DFIG for wind power generation application.

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