• Title/Summary/Keyword: Normal development

Search Result 4,660, Processing Time 0.035 seconds

Age-Related Physiological Consideration (노화와 관련된 생리학적 변화에 대한 고찰)

  • Park Kyu-Hyun
    • The Journal of Korean Physical Therapy
    • /
    • v.16 no.1
    • /
    • pp.49-59
    • /
    • 2004
  • Chronic and acute musculoskeletal disorders associated with aging are a challenges to the physical therapy. An understanding of the pathophysiology of normal and pathological aging is imperative for making effective clinical decisions. The foundation for understanding the aging musculoskeletal system is understanding the sequence of normal musculoskeletal development, which begins prenatally

  • PDF

Effects of Lead and Zinc on the Fertilization and Embryo Development of the Sea Urchin (Hemicentrotus pulcherrimus) (납과 아연이 말똥성게(Hemicentrotus pulcherrimus)의 수정 및 배아 발생에 미치는 영향)

  • Hwang, Un-Ki;Heo, Seung;Park, Jong-Soo;Kang, Han Seung
    • Korean Journal of Environmental Biology
    • /
    • v.30 no.2
    • /
    • pp.128-135
    • /
    • 2012
  • The individual toxicity of lead (Pb) and zinc (Zn) has been investigated by using the sea urchin (Hemicentrotus pulcherrimus) germ cell and pluteus-larvae. The gametotoxic and embryotoxic effects of Pb and Zn on H. pulcherrimus were each investigated at 31, 63, 125, 250, 500 ppb and 16, 31, 63, 125, 250 ppb, respectively. Spawning was induced by 0.5 M KCl solution and the fertilization and normal embryogenesis rates test were performed for 10 min and 64 h after fertilization, respectively. In exposure to Pb, the fertilization rate was not significantly changed compared with control but normal embryogenesis rate was significantly decreased with concentration dependent manner. Fertilization and normal embryogenesis rates showed a significant decreased with concentration dependent manner in exposed to Zn. The normal embryogenesis rates were significantly inhibited in exposed to Pb ($EC_{50}$=45.13 ppb, 95% Cl=40.12~50.05 ppb) and Zn ($EC_{50}$=19.82 ppb, 95% Cl=18.26~21.31 ppb). In exposure to Pb and Zn, the NOEC of normal embryogenesis rate was <31.25 and <15.63 ppb, respectively. The LOEC showed each 31.25 and 15.63 ppb in exposed to Pb and Zn. These results suggest that the early embryo development of H. pulcherrimus is highly sensitive to heavy metals such as Pb and Zn, H. pulcherrimus can be used as a test organism for risk assessment in marine ecosystems.

Conceptions Toward Career Development and Occupational View between Giftedness in Computer Science and Normal Students in Elementary School (초등정보과학영재와 일반학생의 진로발달 및 직업관 인식에 대한 조사 연구)

  • Lee, Jaeho;Choi, Seung Hee
    • Journal of Gifted/Talented Education
    • /
    • v.24 no.4
    • /
    • pp.613-628
    • /
    • 2014
  • The purpose of this study is to compare the differences of the career development and the occupational view between giftedness in computer science and normal students in elementary school, so the results of this study provide assistance to the teacher for the direction and guidance on the career education of the giftedness in computer science in elementary school. This survey is based on 82 giftedness in computer science and 167 normal elementary school students. The questionnaires used in the study contain questions asking regarding the career development and the occupational view. The results of this study were as follows : First, according to the consciousness analysis result about career, the giftedness in computer science choose to be scientific technicians, the normal students choose to be artists. The both groups get career information from their parents, but they usually don't get career counseling from teachers. The education of giftedness in computer science does not contribute to changing their dreams, while normal students have no interest in computer science. Second, according to the career development analysis result, in comparison with non-gifted students, the gifted in information science had more success in all domains of career development. Third, according to the occupational view analysis result, the information science gifted students had higher meaningful rate than the normal students. Intrinsic domain' had higher meaningful rate among the subordinate domains, there is no difference in 'extrinsic domain' and 'incidental domain' between the information science gifted students and the normal students. Fourth, according to the correlation analysis result of the career development and the occupational view, there is a positive correlation in all domains of them. The high they are in the career development, the more they have the certain occupational view. Likewise, if they have the certain occupational view, they will be more successful in career development. Based on the findings of this research, the directing and guidance on the career education of giftedness in computer science in elementary school is same as the followings. We should educate parents regarding information about career for students who are under the influence of parents greatly and indicate them to apply to their children appropriately. In addition, for making them to have the positive image of the computer science, teacher should provide more information about the area of information and form various curriculums to induce more interests about computer science. We need to strengthen the career education for guiding the gifted to assist them to establish their own goal and realize them how to study and choose their career in the future. In school education field, it must develop and manage the definite and empirical program, not the career development program which is focused on only entrance into advanced school, to boost self-realization ability and the suitable career education program based on the correct understanding on giftedness in computer science. For this, through steady trying and research, teachers should be eater to develop the career education for students. Also, we have to implement the internal stability career education program, so it will help students to be aware of their job and career; therefore, students will be able to plan and prepare for their career in this rapid changing world.

A Study on the Activity of Alkaline Phosphatase of Rat Oviduct During Early Embryonic Development (흰쥐 초기배아 발생기간 중 수란관조직의 알카리성 Phosphatase활성도에 관한 연구)

  • Kim, Sung-Rye;Kim, Moon-Kyoo
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.18 no.1
    • /
    • pp.41-48
    • /
    • 1991
  • The present investigation has been undertaken to elucidate the functional role of ovarian steroids on the mechanism of oviduct differentiation during early embryonic development in rat. The activity of alkaline phosphatase (ALPase) was measured in the oviduct tissue under different steroids treatment regime on day 9 pregnancy. The ALPase activity of the oviduct of pseudopregnant rat was compared with that of normal pregnant rat. The results of day 9 pregnancy rat oviduct clearly demonstrated that $17{\beta}-estradiol$ and progesterone were effective in pseudopregnant rat oviduct. In the ovary intact group the ALPase activity was similar in both of normal and pseudopregnant oviduct, but in the $17{\beta}-estradiol$ treated group the ALPase activity in normal pregnancy was significantly higher than that in pseudopregnancy. The effect of estradiol on the normal pregnant rat oviduct was apparently found on day 3 and day 9 pregnancy. This study, therefore, clearly demonstrates that $17{\beta}-estradiol$ is much potent in oviduct tissue differentiation. It is suggested that absence of $17{\beta}-estradiol$ effect on pseudopregnant rat oviduct is due to there is no embryo passing througth the oviduct.

  • PDF

Analysis of Probability Distribution of Muzzle Velocity for Chrome Plated Barrel (크롬도금 포열의 포구속도 확률분포 특성 분석)

  • Kim, Jaekab;Kim, Jaehoon
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.24 no.4
    • /
    • pp.401-407
    • /
    • 2021
  • To confirm the change of muzzle velocity and the most suitable probability distribution model of the 155 mm K9 howitzer barrel with chrome plating and changed rifling. Using a statistical program, the muzzle velocity were plotted on a normal distribution, a 2-parameter and 3-parameter Weibull distribution on a probability paper. Also, statistical parameters were estimated and muzzle velocity fitness test and probability of K676 charge were plotted. In both the chrome-plated with standard rifling and changed rifling for K9 barrel, the 2-parameter and 3-parameter Weibull distribution were skewed to the left compared to the normal distribution. It was confirmed that the muzzle velocity of the K9 barrel with chromium-plated is suitable for the normal distribution and 3-parameter Weibull distribution model.

Statistical Method of Ranking Candidate Genes for the Biomarker

  • Kim, Byung-Soo;Kim, In-Young;Lee, Sun-Ho;Rha, Sun-Young
    • Communications for Statistical Applications and Methods
    • /
    • v.14 no.1
    • /
    • pp.169-182
    • /
    • 2007
  • Receive operating characteristic (ROC) approach can be employed to rank candidate genes from a microarray experiment, in particular, for the biomarker development with the purpose of population screening of a cancer. In the cancer microarray experiment based on n patients the researcher often wants to compare the tumor tissue with the normal tissue within the same individual using a common reference RNA. Ideally, this experiment produces n pairs of microarray data. However, it is often the case that there are missing values either in the normal or tumor tissue data. Practically, we have $n_1$ pairs of complete observations, $n_2$ "normal only" and $n_3$ "tumor only" data for the microarray. We refer to this data set as a mixed data set. We develop a ROC approach on the mixed data set to rank candidate genes for the biomarker development for the colorectal cancer screening. It turns out that the correlation between two ranks in terms of ROC and t statistics based on the top 50 genes of ROC rank is less than 0.6. This result indicates that employing a right approach of ranking candidate genes for the biomarker development is important for the allocation of resources.

Communication-Power Overhead Reduction Method Using Template-Based Linear Approximation in Lightweight ECG Measurement Embedded Device (경량화된 심전도 측정 임베디드 장비에서 템플릿 기반 직선근사화를 이용한 통신오버헤드 감소 기법)

  • Lee, Seungmin;Park, Kil-Houm;Park, Daejin
    • IEMEK Journal of Embedded Systems and Applications
    • /
    • v.15 no.5
    • /
    • pp.205-214
    • /
    • 2020
  • With the recent development of hardware and software technology, interest in the development of wearable devices is increasing. In particular, wearable devices require algorithms suitable for low-power and low-capacity embedded devices. Among them, there is an increasing demand for a signal compression algorithm that reduces communication overhead, in order to increase the efficiency of storage and transmission of electrocardiogram (ECG) signals requiring long-time measurement. Because normal beats occupy most of the signal with similar shapes, a high rate of signal compression is possible if normal beats are represented by a template. In this paper, we propose an algorithm for determining the normal beat template using the template cluster and Pearson similarity. Also, the template is expressed effectively as a few vertices through linear approximation algorithm. In experiment of Datum 234 of MIT-BIH arrhythmia database (MIT-BIH ADB) provided by Physionet, a compression ratio was 33.44:1, and an average distribution of root mean square error (RMSE) was 1.55%.

The Effect of Physical Therapy after Selective Posterior Rhizotomy patients (선택적 척수후근 절제술 후 물리치료의 효과)

  • Her, Jin-Gang;Park, Sung-Hark
    • Journal of Korean Physical Therapy Science
    • /
    • v.6 no.2
    • /
    • pp.989-995
    • /
    • 1999
  • Musclee spasticity of Cerebral Palsy children brings abnormal posture and becomes delayed for Normal Motor Development. The objective of this study is to discover the effects of physical therapy on subject paitient' s posture and Normal Motor Development after Selective Posterior rhizotomy. The subject patients were 280 children who had physical therapy for about 4 to 6 months after Selective Posterior Rhizotomy. The sum of points both pre and post operation by using Locomotion stage of Vojta and Arens's grading of Gross Motor Function were compared and evaluated. Among total of 280 Cerebral Palsy children who had 4 to 6 months of physical therapy ; total of 206 children(197 by grade 1, 9 by grade 2) has increased out of 218 spasticity type children, and totoal of 42 has increased (by gradel) out of 48 Athetoid type, and total of 8 jas increased (by grade 1) out of 14 Mixed type Physical therapy for Cerebral Palsy children after Selective Posterior Rhizotomy has enhanced Normal Motor Development and their posture. The therapy also has shown the results of shortening the therapy period and better treatment results.

  • PDF

Nutritional Components of Alaska Pollock Theragra chalcogramma Roe of Various Grades (명란의 등급별 영양 특성)

  • Park, Young Joo;Jeong, Hyo-Pin;Kim, Jin-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.52 no.2
    • /
    • pp.105-113
    • /
    • 2019
  • The objective of this study was to investigate Alaska pollock Theragra chalcogramma roe grade distribution among blocks and its nutritional components by grade. M grade roe was predominantly distributed in blocks labeled as L and M (52.1 and 82.8%, respectively), and S grade roe was mainly found in blocks labeled as S (98.6%). Products labeled as containing KB and KC grade roe contained 77.1 and 65.5% normal roe, respectively. Among the five roe grades (L, M, S, G, and Off), total amino acid content was higher in normal roe than in abnormal roe. The major amino acids found in normal roe were leucine, aspartic acid, and glutamic acid, whereas G and Off grade roe contained leucine and glutamic acid, but not aspartic acid. The calcium, phosphorus, potassium, and iron contents of the five roe grades were within the ranges 13.0-20.0, 314.4-392.0, 124.1-157.7, and 1.7-2.2 mg/100 g, respectively. The five roe grades contained total fatty acid contents of 765-1,252 mg/100 g, with no significant differences among grades. The major fatty acids were 16:0, 18:1n-9, 20:5n-3, and 22:6n-3.

Anti-oxidant Effect of Wasabia Japonica Extracts (고추냉이 추출액의 항산화 효과)

  • Lee, Young-Sun
    • Journal of Society of Preventive Korean Medicine
    • /
    • v.12 no.1
    • /
    • pp.119-126
    • /
    • 2008
  • This study was carried out to investigate the anti-oxidant effect of Wasabia japonica(WJ). The anti-oxidant activities of various extracts from WJ were investigated. The water and ethanol extracts of WJ leaf were found to cause significant free radical scavenging effects on DPPH and nitric oxide(NO). Sprague-Dawley male rats were randomly assigned to one normal diet and three high cholesterol diet groups which contained 1%(w/w) cholesterol. After 4weeks cholesterol diet, the groups of high cholesterol diet were classified to control(normal diet only), WJR5(normal diet and 5% WJ root) and WJL5(normal diet and 5% WJ leaf). Liver xanthine oxidase(XO) activity in the rats of high cholesterol diet was decreased up to the levels of normal diet group according to WJ diet. The results indicated that WJ possesses antioxidant effects through free radical scavenging effects on DPPH, NO and the decreasing of XO activity. In view of these results, WJ is expected to be an effective material for the anti-oxidant.

  • PDF