• Korean Journal of Adult Nursing
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• v.23 no.1
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• pp.40-49
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• 2011

Purpose: This study aimed to identify the prevalence of mild cognitive impairment (MCI) among a group of community-dwelling elderly and to determine if there were differences in general characteristics, activities of daily living (ADL), perceived health status (PHS) between the MCI group and group of elderly with normal cognitive function. Methods: This study utilized a descriptive survey design. Six hundred and five subjects over the age 65 were recruited from an S public health center, Seoul. Data were gathered through a variety of instruments: MoCA-K, K-MMSE, K-MBI, S-IADL, and PHS scale. Data were analyzed by SPSS/WIN 18.0 using descriptive statistics, Chi-Square test and t-test. Results: The prevalence of MCI among the subjects was 46.0%. Differences in IADL, PHS, age, education, sex, and residing with a spouse were statistically significant between groups. The MCI group had lower IADL, lower PHS, were older, and had lower educational levels than the group with normal cognitive function. Further, the MCI group was less likely to live with a spouse. Conclusion: It is suggested that MCI group should be targeted in developing and implementing nursing strategies to prevent dementia and improve the elderly cognitive function.

• The korean journal of orthodontics
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• v.24 no.1 s.44
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• pp.161-180
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• 1994

This study was performed to investigate the midline having the least difference between the right and left structure among the lines that had been used in the submentovertex analysis and secondarily to know the distribution of asymmetry and it's degree existed normal persons and asymmetric patients. The subjects consisted of 40 normal adult patients and 40 asymmetric adult patients. The computerized analyses from submentovertex cepholometric radiograph were carried out. The results were as follows : 1. The right and left difference of the perpendicular bisecting line between right and left foramen spinosum was larger than the other midlines in the anterior area and it was decreased gradually as it progressed posteriorly. Specially the difference of this line was the smallest in the area where there was foramen spinosum. 2. The right and left difference of the perpendicular line through crista gali to the line between right and left foramen spinosum was smaller than the other midlines in the anterior area and it was increased gradually as it progressed posteriorly. 3. The right and left difference of the line between crista gali and anterior process of atlas was constant and smaller than the other midlines. 4. Asymmetry was a common finding in both normal and asymmetry group and left or right dominance of asymmetry was not statistically singnificant. 5. When the analyses were undertaken after submentovertex radiogram was divided into cranial base, upper face and lower face, the more inferior part showed relative asymmetry than the more superior part.

• BMB Reports
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• v.36 no.1
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• pp.43-48
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• 2003

Understanding the process of carcinogenesis will involve both the accumulation of many scientific facts derived from molecular, biochemical, cellular, physiological, whole animal experiments and epidemiological studies, as well as from conceptual understanding as to how to order and integrate those facts. From decades of cancer research, a number of the "hallmarks of cancer" have been identified, as well as their attendant concepts, including oncogenes, tumor suppressor genes, cell cycle biochemistry, hypotheses of metastasis, angiogenesis, etc. While all these "hallmarks" are well known, two important concepts, with their associated scientific observations, have been generally ignored by many in the cancer research field. The objective of the short review is to highlight the concept of the role of human adult pluri-potent stem cells as "target cells" for the carcinogenic process and the concept of the role of gap junctional intercellular communication in the multi-stage, multi-mechanism process of carcinogenesis. With these two concepts, an attempt has been made to integrate the other well-known concepts, such as the multi-stage, multi-mechanisn or the "initiation/promotion/progression" hypothesis; the stem cell theory of carcinogenesis; the oncogene/tumor suppression theory and the mutation/epigenetic theories of carcinogenesis. This new "integrative" theory tries to explain the well-known "hallmarks" of cancers, including the observation that cancer cells lack either heterologous or homologous gap junctional intercellular communication whereas normal human adult stem cells do not have expressed or functional gap junctional intercellular communication. On the other hand, their normal differentiated, non-stem cell derivatives do express connexins and express gap junctional intercellular communication during their differentiation. Examination of the roles of chemical tumor promoters, oncogenes, connexin knock-out mice and roles of genetically-engineered tumor and normal cells with connexin and anti-sense connexin genes, respectively, seems to provide evidence which is consistent with the roles of both stem cells and gap junctional communication playing a major role in carcinogenesis. The integrative hypothesis provides new strategies for chemoprevention and chemotherapy which focuses on modulating connexin gene expression or gap junctional intercellular communication in the premalignant and malignant cells, respectively.

• Korean Journal of Adult Nursing
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• v.12 no.3
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• pp.396-406
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• 2000

The purpose of the study was to investigate Body Mass Index (BMI), the perception of weight problem and the level of self-esteem and depression in high school and college females. The convenience sample consisted of 303 high school females and 481 college females. Data were collected between November 1999 and December 1999. Subjects ranged in age from 15 years and 26 years. BMI was calculated based on the subject's self-reported body weight and height. Self-perception of having a weight problem was evaluated by a single item question. The Rosenberg's Self-Esteem Scale and the Center for Epidemiologic Studies Depression Scale were utilized to measure the level of self-esteem and depression symptoms. BMI mean scores were 19.92 and 19.83 in high school females and college females, respectively. Based on BMI, 79.2 percent of high school females and 85.2 percent of college females were in a normal weight range. Only 2.6 percent of high school females and 1.5 percent college females were obese. Both high school and college females perceived their body weight problem as moderately severe. The mean scores of depression were 20.33 in high school females and 21.69 in college females. Sixty percent of high school females were depressed and 73.4 percent of college students. There was no significant difference between two groups in BMI. However, high school females perceived their weight problem more severe than college females. College females had higher levels of self-esteem and depression than high school females. BMI and perceptions of weight problem revealed a positive relationship in both groups. Results of the study revealed that a perception of weight problem contributed significantly to predict the level of self-esteem and depression in both groups. BMI score had significant effect on only college females' self-esteem. In the study, even though the mean score of BMI was in a normal range, subjects perceived their weight problems as moderatley severe. Since the perception of a weight problem influenced the level of self-esteem and depression, health care providers need to teach them about the normal weight range in BMI criteria.

• Journal of the Korean Society of Physical Medicine
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• v.13 no.2
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• pp.109-114
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• 2018

PURPOSE: The purpose of this study conducted the experiment to check change of ability to grip depending on normal male adult's elbow flexion angle and the effect of kinesiology tape application. METHODS: Normal male adults who studies in H university where located in Kyoungbook state and did not have any factors like fracture, osteoarthritis, deformities and non-neurologic issue which might influence the result of this study were selected as subjects. Elbow of subjects were applied by 5cm wideness kinesiology tape and elbow's angle was selected by $0^{\circ}$, $45^{\circ}$, $90^{\circ}$, $135^{\circ}$ using Goniometer. The change of ability to grip depending on flexion was measured by an electronic dynamometer before and after taping. RESULTS: Before and after taping elbow joint, both ability to grip decrease in more flexion angle and $135^{\circ}$ of elbow flexion was lowest value, 299.84N. Using kinesiology tape, neutral position $0^{\circ}$ was the highest value, 352.26N. The lowest was 331.68N on $135^{\circ}$. According to verifying the change of ability to grip depending on elbow flexion and the change of ability to grip after taping with paired t-test, the result was p<.05, there was significant difference. CONCLUSION: Using electronic dynamometer and estimating the ability to grip after and before kinesiology tape, the ability to grip decrease in more elbow flexion. The ability to grip after using kinesiology tape was relatively higher than before taping.

• Korean Journal of Community Nutrition
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• v.16 no.1
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• pp.126-135
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• 2011

Obesity is characterized by increased storage of fatty acids in an adipose tissue and closely associated with the development of insulin resistance and cardiovascular diseases (CVD) through secretion of adipokines. This study was done to compare serum insulin, leptin, adiponectin and high sensitivity C-reactive protein (hs-CRP) levels according to body masss index (BMI) in Korean adult women aged 19 to 50. In addition, we examined the association of BMI, serum lipids and Homa-IR with serum adiponectin, leptin and hs-CRP levels. The subjects were divided into 3 groups by their BMI, normal weight (BMI ${\leq}$ 22.9, n = 30), overweight (23.0 ${\leq}$ BMI ${\leq}$ 24.9, n = 71) and obese group (25.0 ${\leq}$ BMI, n = 59). Serum levels of total-cholesterol, TG, and LDL-cholesterol were significantly higher in obese group than in normal weight group. LDL/HDL ratio and AI were significantly higher in obese group than in normal or overweight group. Fasting serum levels of glucose and insulin and Homa-IR as a marker of insulin resistance were significantly higher in obese group than in overweight group. Serum leptin level was significantly higher in obese group while serum adiponectin level was significantly lower in obese group compared to other two groups. hs-CRP was significantly increased in obese group. Correlation data show that serum adiponectin level was positively correlated with serum HDLcholesterol level and was negatively correlated with BMI, WC, TG, LDL-cholesterol, Homa-IR, hs-CRP and leptin. In addition, serum leptin level was positively correlated with BMI, WC, glucose, insulin, Homa-IR and hs-CRP. These results might imply that the regulation of key adipokines such as adiponectin might be a strategy for the prevention or treatment of obesity-associated diseases such as diabetes and CVD.

• Korean Journal of Community Nutrition
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• v.5 no.2
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• pp.152-160
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• 2000

The purpose of this study was to investigate zinc and copper metabolism and risk factors of chronic diseases in 20 normal adults women. The daily intake, excretions in urine and feces, and serum levels of zinc and copper were determined by 24-hr food records and chemical analysis. The results were summarized as follows. mean age, body weight and BMI were 22.88 years, 54.65kg and 21.28kg/$m^2$ respectively. Mean daily intakes of energy and protein were 1578.84㎉(79% of RDA) and 52.05g (87% of RDA). The zinc and copper intake, excrestion in urine and feces were 7093.23$\mu\textrm{g}$(59% of RDA/2093.87$\mu\textrm{g}$, 203.50$\mu\textrm{g}$/39.87$\mu\textrm{g}$ and 3416.41$\mu\textrm{g}$/857.62$\mu\textrm{g}$, respectively. The serum levels of fasting glucose, insulin, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, zinc and copper were 76.60mg/㎗, 15.66IU/㎗, 160.30mg/㎗, 50.95mg/㎗, 89.80mg/㎗, 89.79mg/㎗, 95.65$\mu\textrm{g}$/㎗ and 73.28$\mu\textrm{g}$/㎗ respectively. Dietary ratio of Zn to Cu was shown to have significant positive correlations with serum insulin, total cholesterol, LDL-cholesterol. The urinary ratio of Zn to Cu was shown to have significant positive correlations with triglyceride. The serum copper level was shown to have significant negative correlations with serum total cholesterol and LDL-cholesterol. In summary, Zn consumption of adult women in their normal diet does not meet the Zn requirement for Koreans. Also, intakes of Zn and Cu may effect the glucose metabolism and cardiovascular diseases. Therefore, to increase the Zn intake and to maintain an appropriate intake ratio of Zn to Cu, nutrition education needs to be implemented.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.24 no.2
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• pp.51-58
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• 2018

Backdround: Using RUSI (Rehabilitation Ultra Sound Imiging) method, which showed high reliability in soft tissue measurements, we compared the muscle relax and contraction, sex, and physical characteristics of the activity of the multifidus muscle in patients with chronic low back pain and normal subjects. Methods: In this study, 16 patients (male: 8, female: 8) with chronic low back pain and 16 healthy adult (male: 8, female: 8) were participated. Subjects lied prone posture on the table with elbow flexed $90^{\circ}$ and shoulder abducted $120^{\circ}$ (starting position). Test was applied two types that muscle relax position and muscle contraction position. Muscle relax position is equal to starting position and muscle contraction position is that upper extremity lift up about 5cm from the table. We measured the thickness of the multifidus muscle in each position by ultrasound. Results: There was a statistically significant difference between the two groups in deviation of Both Side Difference of Activated resting-Arm Lifting Ratio according to posture change between the chronic low back pain patient group and the normal group. Conclusion: The result of this study support previous study showing that there is an imbalance in the activity of multifidus in patients with chronic low back pain.

• The korean journal of orthodontics
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• v.10 no.1
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• pp.29-36
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• 1980

Inclined plane, one of frequently used orthodontic appliances, may cause posterior displacement of mandible and injure the normal growth of temporomandibular joint. So author carried out the mandibular posterior displacement experimentally induced by inserting inclined plane in the rat incisors in order to investigate the histological reactions occuring in the temporomandibular joint of experimental animals. Following results were obtained. 1. The posterior displacement of condyle resulted in the widening of anterior synovial space with anterior condylar hyperplasia and posterior condylar atrophy. In addition, tissue changes were more severe in young rats than in adult rats. 2. The tissue reactions were localized only to condylar head ana there were no evidence of traumatic features in young rats. In adult rats, hemorrhage was an additional finding 1 week after experiment. 3. The remodelling processes were accompanied by the increasing or reduction of fibrous layer and subsequent replacement by cartilage layer occured massively and abruptly in young rats, it occured slightly and slowly in adult rats. 4. The remodelling process of injured condyle occured from 1 week to 4 weeks after experiment and completed between 8 weeks after experiment.

• Korean Journal of Adult Nursing
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• v.24 no.5
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• pp.441-453
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• 2012

Purpose: This secondary data analysis study was aimed at identifying the factors related to the patterns of alcohol use (normal alcohol use, hazardous alcohol use, and alcohol dependence) in the Korean adult. Methods: This study analyzed the cross-sectional data from 230,715 Korean adults aged 19 year and older who participated in the 2009 Korean Community Health Survey. Multinomial logistic regression was used to uncover associations between demographic, health related factors and the patterns of alcohol use. Results: The patterns of alcohol use was differentiated from the sociodemographic variables (residential area, gender, age, marital status, educational level, monthly income, and occupation) and with health related factors (smoking status, hours of sleep, body mass index, pain or discomfort, subjective health, stress level, liver disease, cardio/cerebro vascular disease, and depression). Hazardous alcohol use was lower in rural areas and lower among women, but higher among people who smoke, reported severe stress, and/or depression. Similarly, alcohol dependence was lower among women and among those in rural areas, and was more likely associated with those who smoke, have severe stress and depression. Conclusion: A number of factors are associated with patterns of drinking. Smoking, severe stress and depression seems to confound the problems of alcohol use. Additional research is needed to isolate those factors that are the most important influencing the use of alcohol.