• 대기
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• 제27권4호
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• pp.445-453
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• 2017

This study investigates turbulent flow around a square cylinder mounted on a flat surface at high Reynolds number using a large-eddy simulation (LES) model, particularly focusing on vortex streets behind the square cylinder. Total 9 simulation cases with different inflow wind directions, inflow wind speeds, and cylinder widths in the x- and y-directions are considered to examine the effects of inflow wind direction, speed, and cylinder widths on turbulent flow and vortex streets. In the control case, the inflow wind parallel to the x-direction has a maximum speed of $5m\;s^{-1}$ and the width and height of the cylinder are 50 m and 200 m, respectively. In all cases, down-drafts in front of the cylinder and updrafts, wakes, and vortex streets behind the cylinder appear. Low-speed flow below the cylinder height and high-speed flow above it are mixed behind the cylinder, resulting in strong negative vertical turbulent momentum flux at the boundary. Accordingly, the magnitude of the vertical turbulent momentum flux is the largest near the cylinder top. In the case of an inflow wind direction of $45^{\circ}$, the height of the boundary is lower than in other cases. As the inflow wind speed increases, the magnitude of the peak in the vertical profile of mean turbulent momentum flux increases due to the increase in speed difference between the low-speed and high-speed flows. As the cylinder width in the y-direction increases, the height of the boundary increases due to the enhanced updrafts near the top of the cylinder. In addition, the magnitude of the peak of the mean turbulent momentum flux increases because the low-speed flow region expands. Spectral analysis shows that the non-dimensional vortex generation frequency in the control case is 0.2 and that the cylinder width in the y-direction and the inflow wind direction affect the non-dimensional vortex generation frequency. The non-dimensional vortex generation frequency increases as the projected width of the cylinder normal to the inflow direction increases.

• 대한한방부인과학회지
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• 제23권2호
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• pp.71-84
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• 2010

Purpose: In the theory of traditional medicine, Glenditsia spina(GS) can resolve carbuncle, relive swelling, dispel wind and destroy parasites. This study was designed to investigate the effects of GS on gene expression of ovarian tissue in polycystic ovary syndrome(PCOS) rats. Methods: In this experiment, female rats injected with a single dose of 2 mg estradiol valerate(EV) and GS was given for 5 weeks. The genetic profile for the effects on ovarian tissue in PCOS rats was measured using microarray technique, and the functional analysis on these genes was conducted. Results: 985 genes were increased in control and restored to normal level in GS group. (B), 733 genes were decreased in control group and restored to normal level in GS group. (F). Metabolic pathways related in B group genes were Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Small cell lung cancer, Type I diabetes mellitus. Metabolic pathways related in F group genes were Antigen processing and present, Adipocytokine signalling pathway, Focal adhesion, ECM-receptor interaction, Pancreatic cancer, Notch signalling pathway, Tight junction. The network of total protein interactions was measured using cytoscape program, and some key molecules, such as c-Fos, c-Myc, ABL1 related in B group, MAPK8, RASA1, CALR related in F group that can be used for elucidation of therapeutical mechanism of medicine in future were identified. Conclusion: These results suggest possibility of GS as anti-cancer and anti-hyperplasia drug in PCOS. In addition, the present author also suggests that related mechanisms are involved in suppression of proto-oncogene such as c-Fos, c-Myc and ABL1, and in regulation of cell cycle such as RASA1.

• Structural Engineering and Mechanics
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• 제53권5호
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• pp.881-896
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• 2015

In this study, a method for fatigue performance estimation of deepwater steel catenary riser (SCR) under short-term vortex-induced vibration was investigated for selected S-N curves. General tendency between S-N curve capacity and fatigue performance was analysed. SCRs are generally used to transport produced oil and gas or to export separated oil and gas, and are exposed to various environmental loads in terms of current, wave, wind and others. Current is closely related with VIV and it affects fatigue life of riser structures significantly. In this regards, the process of appropriate S-N curve selection was performed in the initial design stage based on the scale of fabrication-related initial imperfections such as welding, hot spot, crack, stress concentration factor, and others. To draw the general tendency, the effects of stress concentration factor (SCF), S-N curve type, current profile, and three different sizes of SCRs were considered, and the relationship between S-N curve capacity and short-term VIV fatigue performance of SCR was derived. In case of S-N curve selection, DNV (2012) guideline was adopted and four different current profiles of the Gulf of Mexico (normal condition and Hurricane condition) and Brazil (Amazon basin and Campos basin) were considered. The obtained results will be useful to select the S-N curve for deepwater SCRs and also to understand the relationship between S-N curve capacity and short-term VIV fatigue performance of deepwater SCRs.