• Title/Summary/Keyword: Normal Distributions

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Characterization and Formation Mechanisms of Clogging Materials in Groundwater Wells, Mt. Geumjeong Area, Busan, Korea (부산 금정산 일대 지하수공내 공막힘 물질의 특징과 형성원인)

  • Choo, Chang-Oh;Hamm, Se-Yeong;Lee, Jeong-Hwan;Lee, Chung-Mo;Choo, Youn-Woo;Han, Suk-Jong;Kim, Moo-Jin;Cho, Heuy-Nam
    • The Journal of Engineering Geology
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    • v.22 no.1
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    • pp.67-81
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    • 2012
  • The physical, chemical, and biological properties of clogging materials formed within groundwater wells in the Mt. Geumjeong area, Busan, Korea, were characterized. The particle size distribution (PSD) of clogging materials was measured by a laser analyzer. XRD, SEM, and TEM analyses were performed to obtain mineralogical information on the clogging materials, with an emphasis on identifying and characterizing the mineral species. In most cases, PSD data exhibited an near log-normal distribution; however, variations in frequency distribution were found in some intervals (bi-or trimodal distributions), raising the possibility that particles originated from several sources or were formed at different times. XRD data revealed that the clogging materials were mainly amorphous ironhydroxides such as goethite, ferrihydrite, and lapidocrocite, with lesser amounts of Fe, Mn, and Zn metals and silicates such as quartz, feldspar, micas, and smectite. Reddish brown material was amorphous hydrous ferriciron (HFO), and dark red and dark black materials were Fe, Mn-hydroxides. Greyish white and pale brown materials consisted of silicates. SEM observations indicated that the clogging materials were mainly HFO associated with iron bacteria such as Gallionella and Leptothrix, with small amounts of rock fragments. In TEM analysis, disseminated iron particles were commonly observed in the cell and sheath of iron bacteria, indicating that iron was precipitated in close association with the metabolism of bacterial activity. Rock-forming minerals such as quartz, feldspar, and micas were primarily derived from soils or granite aquifers, which are widely distributed in the study area. The results indicate the importance of elucidating the formation mechanisms of clogging materials to ensure sustainable well capacity.

A Study on Serum Dopamine-${\beta}$-Hydroxylase Activity and Thermostability in a Randomly Selected Population of Adults (정상인 혈청 Dopamine-${\beta}$-Hydroxylase 활성도 및 Thermostability에 관한 검토)

  • Song Dong-Keun;Suh Yoo-Hun;Woo Jong-Inn;Shin Sang-Goo;Park Chan-Woong
    • The Korean Journal of Pharmacology
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    • v.22 no.1 s.38
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    • pp.60-70
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    • 1986
  • Distributions of serum dopamine-${\beta}$-hydroxylase(DBH) activity and thermostability in a randomly selected population of Korean adults were studied to investigate the genetic factor which could exert an influence on the serum DBH activity and thermostability. The results were followings: 1. The mean serum DBH activity in a randomly selected population of adults was $18.3{\pm}4.5$ umol/min/l($mean{\pm}SD;n=327$) which showed no age or sex variation. 2. The frequency distribution showed no isolated subgroup with very low serum DBH activity. 3. When the ratio of enzyme activity after heating $55^{\circ}C$ for 20 minutes to that before heating (heated-to-control or H/C ratio). was used as a measure of thermostability, the mean serum DBH H/C ratio in a randomly selecfld population, of adults was $0.90{\pm}0.17(mean{\pm}SD; n=327)$ which showed no age or sex variation. 4. Serum DBH H/C ratio showed unimodal, homogeneous distribution. 5. There was significant negative correlation between serum DBH activity and H/C ratio(r=-0.39. p<0.01). 6. Subjects with H/C ratio less than 0.1 had significantly higher basal enzyme activity $(22.2{\pm}4.5)$ $(mean{\pm}SD;n=33)$ umo1/min/1 than those with H/C ratio more than 1.09 $(15.5{\pm}3.3)$ $(mean{\pm}SD;n=32)$ umo1/min/1. This study shows that the distribution patterns of serum DBH activity and thermostability of Korean population are considerably different from those of Caucasian and it might be a line of evidence for the different inheritance pattern of plasma DBH enzyme between these racial groups.

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A New Approach with Combined Stereotactic Trans-multiarc Beams for Radiosurgery Based on the Linear Accelerator : Photon Knife (입체적횡다증회전조사를 병합한 방사선수술의 새로운 접근 : 포톤나이프)

  • Choi, Tae-Jin;Kim, Jin-Hee;Kim, Ok-Bae
    • Radiation Oncology Journal
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    • v.14 no.2
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    • pp.149-158
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    • 1996
  • Purpose : To get an accute steepness of dose gradients at outside the target volume in intracranial lesion and a less limitation of beam selection avoiding the high dose at normal brain tissue, this Photon Knife Radiosurgery System was developed in order to provide the three-dimensional dose distribution through the reconstruction of CT scan and the combined stereotactic trans-multiarc beam mode based on linear accelerator photon beam. Materials and methods : This stereotactic radiosurgery, Photon Knife based on linear accelerator photon beam was provided the non-coplanar multiarc and trans-multiarc irradiations. The stereotactic trans-multiarc beam mode can be obtained from the patient position in decubitus. This study has provided the 3-dimensional isodose curve and anatomical structures with the surface rendering technique. The dose distribution from the combined two trans-multiarcs (2M 2TM) was compared to that of four non-coplanar multiarcs (4M) with same collimator size of 25 mm in a diameter and total gantry movements. Results : In this study, it shows that the dose distributions of stereotactic beam mode are significantly depended on the selected couch and gantry angle in same collimator size. Practical dose distribution of combined stereotactic trans-multiarc beam has shown a more small rim thickness than that of the non-coplanar multiarc beam mode in axial, sagittal and coronal plane in our study. 3-Dimensional dose line displayed with surface rendering of irregular target shape is helpful to determine the target dose and to predict the prognosis in follow-up radiosurgery. Conclusions : 3-Dimensional dose line displayed with surface rendering of irregular target shape is essential in stereotactic radiosurgery. This combined stereotactic trans-multiarc beam has shown a less limitation of the selection couch and gantry beam angles for the target surrounding critical organs. It has shown that the dose distribution of combined trans-multiarc beam greatly depended on the couch and gantry angles. In our experiments, the absorbed dose has been decreased to $27%$ / mm in maximum at the interval of $50\%$ to $80\%$ of isodose line.

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Considerations of Environmental Factors Affecting the Detection of Underwater Acoustic Signals in the Continental Regions of the East Coast Sea of Korea

  • Na, Young-Nam;Kim, Young-Gyu;Kim, Young-Sun;Park, Joung-Soo;Kim, Eui-Hyung;Chae, Jin-Hyuk
    • The Journal of the Acoustical Society of Korea
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    • v.20 no.2E
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    • pp.30-45
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    • 2001
  • This study considers the environmental factors affecting propagation loss and sonar performance in the continental regions of the East Coast Sea of Korea. Water mass distributions appear to change dramatically in a few weeks. Simple calculation with the case when the NKCW (North Korean Cold Water) develops shows that the difference in propagation loss may reach in the worst up to 10dB over range 5km. Another factor, an eddy, has typical dimensions of 100-200km in diameter and 150-200m in thickness. Employing a typical eddy and assuming frequency to be 100Hz, its effects on propagation loss appear to make lower the normal formation of convergence zones with which sonars are possible to detect long-range targets. The change of convergence zones may result in 10dB difference in received signals in a given depth. Thermal fronts also appear to be critical restrictions to operating sonars in shallow waters. Assuming frequency to be 200Hz, thermal fronts can make 10dB difference in propagation loss between with and without them over range 20km. An observation made in one site in the East Coast Sea of Korea reveals that internal waves may appear in near-inertial period and their spectra may exist in periods 2-17min. A simulation employing simple internal wave packets gives that they break convergence zones on the bottom, causing the performance degradation of FOM as much as 4dB in frequency 1kHz. An acoustic experiment, using fixed source and receiver at the same site, shows that the received signals fluctuate tremendously with time reaching up to 6.5dB in frequencies 1kHz or less. Ambient noises give negative effects directly on sonar performance. Measurements at some sites in the East Coast Sea of Korea suggest that the noise levels greatly fluctuate with time, for example noon and early morning, mainly due to ship traffics. The average difference in a day may reach 10dB in frequency 200Hz. Another experiment using an array of hydrophones gives that the spectrum levels of ambient noises are highly directional, their difference being as large as 10dB with vertical or horizontal angles. This fact strongly implies that we should obtain in-situ information of noise levels to estimate reasonable sonar performance. As one of non-stationary noise sources, an eel may give serious problems to sonar operation on or under the sea bottoms. Observed eel noises in a pier of water depth 14m appear to have duration time of about 0.4 seconds and frequency ranges of 0.2-2.8kHz. The 'song'of an eel increases ambient noise levels to average 2.16dB in the frequencies concerned, being large enough to degrade detection performance of the sonars on or below sediments. An experiment using hydrophones in water and sediment gives that sensitivity drops of 3-4dB are expected for the hydrophones laid in sediment at frequencies of 0.5-1.5kHz. The SNR difference between in water and in sediment, however, shows large fluctuations rather than stable patterns with the source-receiver ranges.

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Energy Intake according to Expected Body Mass Index of Middle School Students in Seoul (서울 일부지역 중학생의 희망 체질량지수에 따른 에너지 섭취 상태)

  • Ko, Min-Jeong;Bae, Yun-Jung;Kim, Hyun-Jin;Choi, Mi-Kyeong
    • Journal of the East Asian Society of Dietary Life
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    • v.25 no.1
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    • pp.30-38
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    • 2015
  • The purpose of this study was to compare energy intake according to expected body mass index (BMI) in adolescents. A total of 280 middle school students were divided into current or/and expected obesity groups (underweight group; UWG, normal weight group; NWG, and overweight group; OWG) by BMI to compare energy intake and perception on body shape and weight control. The average age of total subjects was 15 years, and the distributions of boys and girls were 52.5% and 47.5%, respectively. The distribution of boys and girls was not significantly different among current obesity groups but was among expected obesity groups (15% and 82% in UWG vs. 71.4% and 16.5% NWG vs. 13.6% and 1.5% in OWG; P<0.001), indicating that girls wanted to lose weight more than boys. For body shape, most subjects in current obesity groups responded "fitness" in UWG (38.7%), "fitness" and "slightly chubby" in NWG (45.5% and 39%), and "slightly chubby" in OWG (65.2%), showing a significant difference (P<0.001). For interest in weight control, most subjects responded "average" in current UWcinterested" in current OWG (52.2%), whereas they responded "very interested" in expected UWG (55.7%), "average" in expected NWG (51.2%), and "not interested" in expected OWG (45.5%), showing a significant difference (P<0.001). The percentage of subjects with experience with weight control was significantly high in current OWG (71.7%), NWG (51.2%) and UWG (34.2%) as well as in expected UWG (57.3%), NWG (40.2%) and OWG (36.4%) in descending order (P<0.001). The daily energy intake of total subjects was 2,057.1 kcal without any significant difference among current obesity groups. However, it was significantly lower in expected UWG than expected NWG and OWG (1,943.1 kcal vs. 2,165.0 kcal or/and 2,152.1 kcal; P<0.001). To sum up these results, girls wanted to lose weight more than boys. The more students wanted to lose weight, the greater their experience and interest in weight control and the lower their energy intake.

Characteristics of Light-evoked Retinal Ganglion Cell Activity with Postnatal Maturation in SD Rat (SD rat 망막신경절세포의 생후 성숙기간에 따른 빛 자극 반응 특성)

  • Ye, Jang-Hee;Goo, Yong-Sook
    • Progress in Medical Physics
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    • v.16 no.4
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    • pp.214-219
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    • 2005
  • As part of Korean retinal prosthesis project, we have provided preliminary experimental results regarding voltage parameters for the stimulation of chemically degenerated rabbit retina. Since our APB-treated chemically degenerated retina is only ON-pathway blocked, now we switch our experiments to more appropriate retinal degeneration model, genetically degenerated retina model (RD mouse: rd/rd (C3H/HeJ)). Before studying with RD mouse, we started control experiments with normal SD rat to understand characteristics of retinal ganglion ceil activity with postnatal maturation in rodents. Ganglion cell activities were recorded with 8${\times}$8 multi-electrode array. Moving spontaneous bursts appeared until postnatal day of 15. During pre-eye opening period, no light evoked response appeared. After postnatal day of 2 weeks (post-eye opening period), ON-, OFF- and ON/OFF response appeared. The fractional distributions of ON, OFF, and ON/OFF ganglion cell is about $40\%,\;50\%$, and $5\%$. The percentage ($\%$) of light evoked response in each dorso-temporal, ventral, and dorso-nasal area of eye is about $50\%,\;37.5\%$ and $12.5\%$, respectively. We concluded that the optimal period for experiment in rodent is about postnatal day of 2${\~}$3 weeks.

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Development of Evaluation Model for ITS Project using the Probabilistic Risk Analysis (확률적 위험도분석을 이용한 ITS사업의 경제성평가모형)

  • Lee, Yong-Taeck;Nam, Doo-Hee;Lim, Kang-Won
    • Journal of Korean Society of Transportation
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    • v.23 no.3 s.81
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    • pp.95-108
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    • 2005
  • The purpose of this study is to develop the ITS evaluation model using the Probabilistic Risk Analysis (PRA) methodology and to demonstrate the goodness-of-fit of the large ITS projects through the comparative analysis between DEA and PRA model. The results of this study are summarized below. First, the evaluation mode] using PRA with Monte-Carlo Simulation(MCS) and Latin-Hypercube Sampling(LHS) is developed and applied to one of ITS projects initiated by local government. The risk factors are categorized with cost, benefit and social-economic factors. Then, PDF(Probability Density Function) parameters of these factors are estimated. The log-normal distribution, beta distribution and triangular distribution are well fitted with the market and delivered price. The triangular and uniform distributions are valid in benefit data from the simulation analysis based on the several deployment scenarios. Second, the decision making rules for the risk analysis of projects for cost and economic feasibility study are suggested. The developed PRA model is applied for the Daejeon metropolitan ITS model deployment project to validate the model. The results of cost analysis shows that Deterministic Project Cost(DPC), Deterministic Total Project Cost(DTPC) is the biased percentile values of CDF produced by PRA model and this project need Contingency Budget(CB) because these values are turned out to be less than Target Value(TV;85% value), Also, this project has high risk of DTPC and DPC because the coefficient of variation(C.V) of DTPC and DPC are 4 and 15 which are less than that of DTPC(19-28) and DPC(22-107) in construction and transportation projects. The results of economic analysis shows that total system and subsystem of this project is in type II, which means the project is economically feasible with high risk. Third, the goodness-of-fit of PRA model is verified by comparing the differences of the results between PRA and DEA model. The difference of evaluation indices is up to 68% in maximum. Because of this, the deployment priority of ITS subsystems are changed in each mode1. In results. ITS evaluation model using PRA considering the project risk with the probability distribution is superior to DEA. It makes proper decision making and the risk factors estimated by PRA model can be controlled by risk management program suggested in this paper. Further research not only to build the database of deployment data but also to develop the methodologies estimating the ITS effects with PRA model is needed to broaden the usage of PRA model for the evaluation of ITS projects.

Stand Structure and Dynamics in Forests around Nari Basin of Ulleung Island, Korea (울릉도 나리분지 주변 산림의 임분구조 및 동태)

  • Chung, Jae-Min;Hwang, Sun-Mi;Kim, Yoo-Mi;Shin, Jae-Kwon;Kim, Myong-Soo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.12 no.1
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    • pp.23-35
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    • 2010
  • For the sustainable conservation of forests within and around the somma of Nari basin in Ulleung Island, the stand structure and dynamics with the aspect, altitude and stand types were estimated by using analyses of importance value, plant species diversity, S$\o$rensen's similarity index and distributions of diameter classes. Results of the importance value analysis with vegetation stories on each stand showed that Fagus engleriana and Acer okamotoanum were dominant in most stands regardless of the aspect and altitude of the forest around the somma of Nari basin and the plant species composition among stands was not significantly different. The forest within Nari basin was composed of pine, beech, alder and deciduous-mixed stand. Moreover, the species composition was greatly different among the four stands. The diversity of plant species within stand was in general higher within Nari basin than around the somma, and among stands within Nari basin, the plant species diversity of pine and deciduous-mixed stand showed higher values than that of beech and alder stands. The similarity index among stands with aspect and altitude showed that the index among stands of eastern, western and northern slope in forest around the somma and forest within the basin ranged from 0.68 to 0.69, and the similarity among four stands with altitude was very high having index range from 0.85 to 0.95. The patterns of diameter class distribution of the major dominant species from four altitude classes followed an almost normal bell-shaped distribution. The results were interpreted as an indication that these forests will in general maintain a stable stand structure. Therefore, despite diverse topographic features around Nari basin, the stand structure and plant species composition among stands were not diversified as expected. For the conservation of diversity of forest plant species and of forest ecosystems, a promising and intensive program should be considered.

Radioimmunotherapy of Nude Mice Bearing Human Colon Carcinoma with I-131 Labeled Anti-carcinoembryonic Antigen Monoclonal Antibody (누드마우스에 이식된 인체대장암에서 I-131표지 항태아성암항원 단일클론항체를 이용한 방사면역치료법 : 치료성적에 관계되는 인자분석)

  • Kim, Byung-Tae;Lee, Kyung-Han;Kim, Sang-Eun;Choi, Yong;Chi, Dae-Yoon;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon;Chung, Hong-Keun
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.3
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    • pp.332-342
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    • 1995
  • This study was designed to evaluate the effects of various factors on the therapeutic effect of the I-131 labeled anti-carcinoembryonic antigen monoclonal antibody(anti-CEA antibody). Tetrazolium-based colorimetric assay (MTT) was used to compare in vitro cytotoxicity of 3 Korean colon cancer cell lines (SNU-C2A, SNU-C4, SNU-C5) for selection of proper 2 cell lines in this study. The changes of the size of tumor which was xenografted to nude mice (balb/c nu/nu) were compared in 4 groups (group treated I-131 labeled anti-CEA antibody, group treated with non-radiolabeled anti-CEA antibody, group treated with I-131 labeled anti-human chorionic gonadotropin monoclonal antibody (anti-hCG antibody) as nonspecific antibody, and group injected with normal saline as a control). Immunohistochemical staining and in vivo autoradiography were performed after excision of the xenografted tumor. The results were as below mentioned. The in vitro cytotoxic effect of I-131 labeled anti-CEA antibody is most prominent in SNU-C5 cell line between 3 cancer cell lines. The changes of xenografted tumor size in both SNU-C4 and SNU-5S cell tumors at the thirteenth day after injection of the antibodies were smallest in the group treated with I-131 labeled anti-CEA antibody (SNU-C4/SNU-C5; 324/342%) comparing with other groups, group treated with anti-CEA antibody (622/660%), group treated with I-131 anti-hCG antibody (538/546%), and control group(1030/724%)(P<0.02 in SNU-C4 and P<0.1 in SNU-C5 at the 13th day after injection of antibodies). On the thirteenth day after injection of the antibodies nude mice were sacreficed to count the radiouptake of tumor and to check the changes of tumor size. Correlations between radiouptake and change of tumor size were calculated in each groups and significant negative correlation was only obtained in the group treated with I-131 anti-CEA antibody (p<0.05). There were no correlations between antigenic expression of carcinoembryonic antigen and distribution of anti-CEA antibody in both SNU-C4 and SNU-C5 cell tumors on immunoperoxidase staining. On in vivo autoradiography the distributions of anti-CEA antibody were heterogeneous and the intensities of binding were various in SNU-C4 and SNU-C5 cell tumors. It is concluded that I-131 labeled tumor-specific monoclonal antibody, anti-CEA antibody is effective in suppressing the xenografted tumor growth and the effect is influenced by sensitivity of tumor cell itself to the radiolabeled antibody and other local factors instead of specificity of antibody.

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Clinical Observation on The Left and Right Facial Palsy (${\cdot}$右側 口眼와斜 患者에 對한 臨床的 考察)

  • Lim, Jin-Ki;Lim, Gyu-Sang;Hwang, Choong-Yeon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.10 no.1
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    • pp.383-402
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    • 1997
  • The author analyzed 155 cases of Facial Palsy, excluding lesions caused by cerebrovascular attacks, who were treated in the Kwang-ju Oriental Medical Hospital of Wonkwang University from March 1996 to September 1996. I've examined the 155 cases in the view of the etiologic distributions, the age, the relationship of the sex and paralytic side, attended symptoms and analyzed 95 cases who were treated over ten times in the view of the ratio of recovery according to the age, anatomic focus, the relations of sex and paralytic side. The following results are obtained. 1. The ratio of punghan(風寒) was $20.64\%$(32 cases), overwork was $18.70\%$(29 cases), stress was $6.44\%$(10 cases), excessive drinking was $3.23\%$(5 cases), teeth pain was $1.93\%$(3 cases), and idiopathy was $38.05\%$(59) and etc. 2. The ratio of stylomastoid pain was $15.48\%$(24 cases), auricular pain was $10.32\%$(16 cases), headache was $4.51\%$(7 cases), eyedried was $4.51\%$(7 cases), taste paralysis was $2.57\%$(4 cases), tinnitus was $2.57\%$(4 cases) and non-significant symptoms was $50.97\%$(79) and etc. 3. The ratio of 2th and 5th decade were $20.00\%$(31 cases), 4th decade was $18.71\%$(29 cases), 3th decade was $16.71\%$(26 cases), 6th decade was $11.61\%$(18 cases), teenagers in $5.81\%$(9 cases), over seventy and under teenagers were $3.23\%$(5 cases), and infant was $0.65\%$(1 case). 4. The ratio of the male-right was $28.39\%$(44 cases), female-right was $25.82\%$(40 cases), male-left was $23.23\%$(36 cases), female-left was $20.65\%$(32 cases) and male-both side was $1.94\%$(3 cases) in order. 5. Topographically, The ratio of the infrachordal lesion was $72.90\%$(113 cases), transgeniculate lesion was $16.13\%$(25 cases), suprageniculate lesion was $5.81\%$(9 cases), infrastapedial lesion was $3.87\%$(6 cases) and suprastapedial lesion was $1.29\%$(2 cases) in order. 6. When we examined the degree of recovery about the 95 patients who were treated over ten times after on attack, normal improvement was seen in $46.32\%$(44 cases), excellent in $7.37\%$(7 cases), good in $12.63\%$(12 cases), fair in $13.68\%$(13 cases), poor in $20.00\%$(19 cases). The total remedial value of the 95 patients who were treated over ten times was revealed $61.58\%$. 7. When we examined the 95 patients who were treated over ten times, the remedial value of the infant was $50.00\%$, under teenagers $43.75\%$, teenagers $37.50\%$, 2th decade $56.82\%$, 3th decade $64.06\%$, 4th decade $55.00\%$, 5th decade $73.53\%$, 6th decade $77.50\%$, over seventieth $68.75\%$. The remedial value of 3th decade, 5th decade, 6th decade, 7th decade and over seventieth were higher than the total remedial value($61.58\%$) 8. In the point of topographical lesion, when we examined the 95 patients who were treated over ten times, the remedial value of infrachordal lesion was $66.78\%$, infrastapedial lesion $58.33\%$, suprastapedial lesion $50.00\%$, transgeniculate lesion $48.44\%$, suprageniculate lesion $31.25\%$, in order. Only the remedial value of Infrachordal($66.78\%$) was higher than the total remedial value($61.58\%$). 9. In the point of the relationship of the sex and the paralytic side, when we examined the 95 patients who were treated over ten times, the remedial value of male-left was $57.29\%$, male-right $61.54\%$, male-both side $58.33\$%, female-left $57.81\%$ and female-right $68.27\%$. Only the remedial value of female-right($68.27\%$) was higher than the total remedial value($61.58\%$). These results demonstrated that in the point of prognostic view there was more concerned with the topographical lesion, body condition than the traditional rule of sex-paralytic relationship that man is awed left paralysis and woman right paralysis.

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