• 제목/요약/키워드: Normal Condition

검색결과 3,198건 처리시간 0.036초

보이차(Camelia sinensis L) 추출물이 ICR Mouse의 급성 알코올 대사에 미치는 효과 (Effects of Water Extracts of Camelia sinensis L on Blood Alcohol Concentration and Activities of Acute Alcohol Metabolic Enzymes in ICR Mouse)

  • 박수현;윤혜경;구성자
    • 동아시아식생활학회지
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    • 제14권6호
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    • pp.634-639
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    • 2004
  • An eight-week-old male ICR mouse, which was induced with acute alcohol and sub-acute alcohol poisoning condition, was administered with bohee tea(Camelia sinensis L) extract. After oral administration of bohee tea and inducement of acute alcohol poisoning condition, the mouses blood alcohol concentration became as low as that of the normal control group. Its decrease rate was 87.26%, in comparison with that of the positive control group. Moreover, its blood GOT activity decreased with a rate of 93.1 % until it reached the normal level, as opposed to that of the positive control group. In addition, the GOT activity, despite rising after the alcohol intake, decreased(p<0.05) significantly after administration of each sample and reached the normal level. The bohee tea group experienced a significant decrease in the GOT activity, compared with the A1codex group and the Drink group. The GPT activity of the Alcodex group decreased by 11 % compared with that of the positive control group. The CTP activity of the bohee tea group decreased by 8.2%, while that of the Drink group decreased by 6.5%(P<0.05). However, there were no significant differences between the results in the control group and those of the test group. The bohee tea group's hepatic ADH activity increased by 22.7% compared with that of the positive control group. On the other hand, the hepatic ADH activity of the Drink group increased by 33.6% while that of the A1codex group increased by 20.4%. On the contrary, the bohee tea extract, the hepatic ALDH did not manifest any significant difference as compared with the normal control group. However, its decrease rate was about 16.67% as compared with that of the positive control group. The Drink group, meanwhile, obtained a decrease rate of about 21.59%.

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정상 보행과 발가락 보행의 하지 근육 근 활성도 비교 (Normal Walking Versus Toe-walking in Healthy Subjects: An Electromyographic Analysis)

  • 김택훈;최홍식;김창인;이진복
    • 한국전문물리치료학회지
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    • 제9권2호
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    • pp.43-50
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    • 2002
  • This study was designed to identify the effects of walking conditions (normal walking vs. toe-walking) on electromyographic (EMG) activity of gastrocnemius, tibialis anterior, and soleus muscle. Seven healthy adult males participated in this study. The exclusion criteria were orthopedic or neurologic disease, congenital anomaly or acquired deformity, or pain in low back or lower extremities. The maximal voluntary isometric contraction for each muscle was used for the reference contraction, and EMG activity of each muscle during normal walking and toe-walking was expressed as a percentage of reference contraction. The gait cycle was determined with two foot switches, and gait was normalized as 100% gait cycle for each condition. The maximal values of EMG activity in terminal stance (30~50% of gait cycle) of each condition were compared for data analysis. No significant differences were found in EMG activity of the tibialis anterior and soleus (p>.05), whereas significant decrement was found in EMG activity of gastrocnemius during toe-walking compared to normal walking (p<.05). There is a limitation to generalize the results of this study, because small number of subjects participated for this study and only EMG was used for data collection. The treatment methods should be developed to improve gait efficiency by substituting the weakened muscles secondary to upper motor neuron, or by strengthening the distal muscles in lower extremity.

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Comparative Proteomic Analyses of the Yeast Saccharomyces cerevisiae KNU5377 Strain Against Menadione-Induced Oxidative Stress

  • Kim, Il-Sup;Yun, Hae-Sun;Jin, In-Gnyol
    • Journal of Microbiology and Biotechnology
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    • 제17권2호
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    • pp.207-217
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    • 2007
  • The Saccharomyces0 cerevisiae KNU5377 strain, which was isolated from spoilage in nature, has the ability to convert biomass to alcohol at high temperatures and it can resist against various stresses [18, 19]. In order to understand the defense mechanisms of the KNU5377 strain under menadione (MD) as oxidative stress, we used several techniques for study: peptide mass fingerprinting (PMF) by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry (MS) followed by two-dimensional (2D) gel electrophoresis, liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS), and surface-enhanced laser desorption ionization-time of flight (SELDI-TOF) technology. Among the 35 proteins identified by MALDI-TOF MS, 19 proteins including Sod1p, Sod2p, Tsa1p, and Ahp1p were induced under stress condition, while 16 proteins were augmented under normal condition. In particular, five proteins, Sod1p, Sod2p, Ahp1p, Rib3p, Yaf9p, and Mnt1p, were induced in only stressed cells. By LC-ESI-MS/MS analysis, 37 proteins were identified in normal cells and 49 proteins were confirmed in the stressed cells. Among the identified proteins, 32 proteins were found in both cells. Five proteins including Yel047cp and Met6p were only upregulated in the normal cells, whereas 17 proteins including Abp1P and Sam1p were elevated in the stressed cells. It was interesting that highly hypothetical proteins such as Ynl281wp, Ygr279cp, Ypl273wp, Ykl133cp, and Ykr074wp were only expressed in the stressed cells. SELDI-TOF analysis using the SAX2 and WCX2 chips showed that highly multiple-specific protein patterns were reproducibly detected in ranges from 2.9 to 27.0 kDa both under normal and stress conditions. Therefore, induction of antioxidant proteins, hypothetical proteins, and low molecular weight proteins were revealed by different proteomic techniques. These results suggest that comparative analyses using proteomics might contribute to elucidate the defense mechanisms of KNU5377 under MD stress.

저진공주사현미경(LV-SEM)을 이용한 목재횡단면의 수축거동관찰 (Observation of Shrinkage Features of Cross Sectional Surface of Wood by LV-SEM)

  • 강춘원;마츠무라 준지;강욱
    • Journal of the Korean Wood Science and Technology
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    • 제36권3호
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    • pp.17-23
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    • 2008
  • 목재의 수축거동을 짧은 시간 내에 세포수준에서 관찰하기 위하여 목재를 함수상태로 관찰할 수 있는 저진공 주사전자현미경(Low-Vacuum Scanning Electron Microscopy)의 경통 내에서 습윤상태의 소형시편을 탈습시켜 건조시키면서 횡단면에서의 목재수축거동을 관찰하였다. 또한 동일한 개체에서 수축율 시험편을 제작하여 실제목재의 수축율을 측정하여 비교하였다. 경통 내의 탈습은 약 20여 분 정도에 완료되어 짧은 시간 내에 목재의 수축과정을 관찰하는 것이 가능하였으며, 수축율 시험편의 수축율과 현미경 내의 탈습에 의한 소시험편의 수축율은 비슷하였다. 목재의 수축율에 기여하는 춘재와 추재의 수축율에 대한 개개의 관찰이 가능하였으며 양자의 수축량은 거의 비슷하게 나타나는 것을 알 수 있었다. 목재의 수축과 세포벽수준에서의 수축을 비교해보면, 목재의 수축은 춘재보다 추재에 의해 좌우되는 사실을 알 수 있었다.

Corrosion and mechanical properties of hot-rolled 0.5%Gd-0.8%B-stainless steels in a simulated nuclear waste treatment solution

  • Jung, Moo Young;Baik, Youl;Choi, Yong;Sohn, D.S.
    • Nuclear Engineering and Technology
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    • 제51권1호
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    • pp.207-213
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    • 2019
  • Corrosion and mechanical behavior of the hot-rolled 0.5%Gd-0.8%B-stainless steel to develop a spent nuclear fuel storage material was studied in a simulated nuclear waste treatment condition with rolling condition. The austenite and ferrite phases of the 0.5%Gd-0.8%B-stainless steels are about 88:12. The average austenite and ferrite grain size of the plane normal to rolling, transverse and normal directions of the hot rolled specimens are about 5.08, 8.94, 19.35, 23.29, 26.00 and 18.11 [${\mu}m$], respectively. The average micro-hardness of the as-cast specimen is 200.4 Hv, whereas, that of the hot-rolled specimen are 220.1, 204.7 and 203.5 [$H_v$] for the plane normal to RD, TD and ND, respectively. The UTS, YS and elongation of the as-cast and the hot-rolled specimen are 699, 484 [MPa], 34.0%, and 654, 432 [MPa] and 33.3%, respectively. The passivity was observed both for the as-cast and the hot rolled specimens in a simulated nuclear waste solution. The corrosion potential and corrosion rate of the as-casted specimens are $-343[mV_{SHE}]$ and $3.26{\times}10^{-7}[A/cm^2]$, whereas, those of the hot rolled specimens with normal to ND, RD and TD are -630, -512 and -620 [$mV_{SHE}$] and $6.12{\times}10^{-7}$, $1.04{\times}10^{-6}$ and $6.92{\times}10^{-7}[A/cm^2]$, respectively. Corrosion tends to occur preferentially Cr and B rich area.

무기영양액 농도 차이가 오이 생육, 무기성분 흡수 및 탄수화물 합성에 미치는 영향 (Influence of Nutrient Supply on Growth, Mineral Nutrients and Carbohydrates in Cucumber (Cucumis sativus L.))

  • 성좌경;박성용;이수연;이예진;이주영;장병춘;고현관;옥용식;김태완;송범헌
    • 한국토양비료학회지
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    • 제43권1호
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    • pp.83-89
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    • 2010
  • 오이의 부위별 생체분석을 통하여 영양진단 가능성을 검토코자, 무기영양액의 양분농도가 결핍된 조건(1/10 Ross 용액) 하에서 오이의 생육, 무기성분의 흡수 및 탄수화물 합성에 관하여 조사하였다. 양분결핍에 의한 오이 생육저해는 처리 후 20일에 나타났다. 양분결핍조건에서 질산태 질소의 흡수는 정상조건에 비해 크게 감소하였으며, 질산태 질소함량은 잎보다 엽병과 줄기에서 높았다. 반면, 암모늄태 질소함량은 생장엽병 및 생장엽에서 뿌리보다 높았다. 양분결핍에 의한 칼리 부족은 생장엽에서 나타났다. 칼슘은 처리간에 유의적인 차이를 보이지 않았으며, 주로 엽병에 분포하였다. 마그네슘은 줄기나 뿌리보다는 잎에 다량 존재하였으며, 나트륨은 칼리와 유사한 경향을 보였으나 함량은 매우 낮았다. 이산화탄소 동화율은 정상 양분조건의 완전생장엽에서 가장 높았으며, 양분결핍조건과 비교할 때 약 1.7배 컸다. 수분이용효율은 처리간에 유의적인 차이는 보이지 않았으나, 정상 양분조건에서 약간 높았다. 수용성 당 함량은 잎에서 가장 높았고, 엽병, 줄기 및 뿌리의 순으로 나타났으며, 오래된 조직보다는 어린 조직에서 높았다. 정상 양분조건의 생장엽에서 측정된 수용성 당 함량은 약 7,200 mg $kg^{-1}$ 이었다. 무기성분과 수용성 당과의 상관관계를 알아본 결과, 마그네슘과 암모늄태 질소가 수용성 당과 고도의 정의 상관관계를 보였다.

폐분획없는 폐동맥의 하행대동맥 기시이상 1례 보고 (Anomalous Systemic Arterial Supply to the Lung without Sequestration A Cases Report)

  • 김요한
    • Journal of Chest Surgery
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    • 제18권1호
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    • pp.104-110
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    • 1985
  • The anomalous systemic arterial supply to the lung without sequestration is an uncommon congenital anomaly characterized by the presence of a part of lung tissue which supplied by an aberrant artery from the aorta or its branch and normal communication with the normal bronchial tree, and it was reported by Huber in 1777 first. It differs from bronchopulmonary sequestration in having normal bronchial communication from the remainder lung and normal lung histology. We experienced a case of anomalous systemic arterial supply to the lung without sequestration, which was confirmed preoperatively. The patient was 16 year old male and came to us with complaints of mild fever and profuse sputum with coughing. Chest film showed a ring-like soft tissue shadow in Rt. middle lung field. Aortogram revealed an aberrant artery originated from abdominal aorta at 12th thoracic vertebral level and supplying a part of Rt. lower lobe of lung. At. the time of operation, an aberrant systemic artery which originated from the abdominal aorta supplying the Rt. lower lobe was noted, and the bronchial communications were normal. After division and ligation of the aberrant artery, Rt. lower lobectomy was performed The postoperative courses were uneventful and the patient was discharged with good condition.

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CRDI 디젤엔진의 피에조 인젝터 불량에 따른 파형 분석에 관한 실험적 연구 (An Experimental Study on the Waveform Analysis According to Troubles of Piezo Injector of CRDI Diesel Engine)

  • 유종식;김철수
    • 한국기계기술학회지
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    • 제20권6호
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    • pp.783-789
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    • 2018
  • This paper investigates the relationship of voltage and current waveform between normal piezo injector and deterioration abnormal piezo injector. The experimental methods using Pico oscilloscope and GDS scan tool are employed to measure current and voltage waveform and fuel pressure of piezo injector. The experiment is carried out during no-load condition. A summary of the important results are as follows. 1) In case of normal injector, the fluctuation of duration time of piezo injector was linearly and regularly decreased with increasing engine speed, but the that of deterioration piezo injector was irregularly decreased with increasing engine speed. 2) In main injection, the peak value of the current waveform of abnormal injector was larger than that of normal injector, the duration time of deteriorated abnormal injector was less than that of normal injector at 800rpm and 1500rpm, but the duration time of deteriorated abnormal injector was larger than that of normal injector at 2000rpm and 3000rpm. This irregularity appears to be caused by the deterioration of the injector.

Dopaminergic Activity가 부종상태에서 혈청 Aldosterone 분비에 미치는영향 (The Effect of Dopaminergic Activity on Aldosterone Secretion in Edematous State)

  • 한봉헌;노흥규
    • 대한핵의학회지
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    • 제19권2호
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    • pp.69-79
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    • 1985
  • To evaluate the effect of dopaminergic activity on aldosterone secretion, the plasma renin activity, serum cortisol and aldosterone were measured by radioimmunoassay in 6 normal controls and 12 patients who had hyponatremia and generalized edema or ascites with possible condition with secondary aldosteronism before and after(15, 30, and 60 min) 15 mg of metoclopramide by iv bolus injection and same method with 500 mg of L-dopa by per oral in 6 normal controls and 12 patients with edema ascites. The result were as follows; 1) The basal level of PRA was higher in patients rather than normal controls but PRA was not influenced by MC or L-dopa administration on both normal controls and patients group. 2) The serum cortisol level was significantly elevated at 30 min after MC injection compared with basal level in normal controls but no significant change was noted in patients group. After L-dopa administration the serum cortisol level was not changed in both normal controls and patients group. 3) The serum aldosterone level was significantly elevated in 15, 30 and 60 min after MC injection in normal controls, and there also same tendency of aldosterone secretion was noticed in patients group. On the other hands, there was no changes in aldosterone level in both normal controls and patients group with L-dopa administration. Above result means that MC stimulate aldosterone secretion by dopaminergic antagonist and aldosterone secretion in normal subject is controlled by maximal tonic dopaminergic inhibition. In edematous patients, however, both of the dopaminergic inhibitory and stimulating effect of PRA, ACTH etc on the aldosterone secretion seems to be variable.

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도어제어장치(DCU)의 PID Control DB 생성장치 (Door Control Unit Create Provision for PID Control DB)

  • 김진헌;권영현;성창용;권민정;이한수
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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    • pp.3065-3072
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    • 2011
  • PID Control Data Base creation device of DCU is safety operation technology of train door. For keeping the normal condition of door, measured value of regular condition and unusual(trouble detected) condition should be recorded by encoding. The door should be measured itself as this value is compared with standard vale. If it's condition of the door and for reaching the datum point and ot does self-diagnosis. This aim for Technical Realization is that carry out safety train operation by using the Estimation Data Base and protect before door-trouble.

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