• 한국의상디자인학회지
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• 제25권1호
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• pp.153-168
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• 2023

Non-representation creates difference and change that can be used as a creative design method that satisfies contradictory requirements for similarity and differentiation. This study drew upon the characteristics of the concept of non-representation expressed in contemporary art and architecture, in which Gilles Deleuze's philosophical thinking was reflected, and analyzed the non-representation depicted in contemporary fashion. The non-representation expressed in contemporary art and architecture is as follows. Non-representation of delaying becoming focuses on reverting to preexisting objects and redefining traditional meaning, thereby delaying the representation of latent meaning. Non-representation of non-becoming removes existing values and typical forms and expresses amorphousness. Non-representation of becoming by repetition or reiteration realizes the difference caused by the passage of time by repeating or overlapping shapes. Non-representation of becoming expresses the transformation of space by flowing through time rather than by actual movement. Non-representation in contemporary fashion shows the following expression characteristics. First, the non-representation of deferring becoming deconstructs the traditional values and forms of clothing and expresses designs by displacement or juxtaposition. Second, the non-representation of non-becoming is expressed concepts unrelated to the body and focus upon amorphous objects that do not become concretized forms. Third, generative non-representation by repetition and overlap expresses the possibility of change by overlapping clothing items or details expressed by repeating segmented objects. Fourth, generative non-representation by movement reproduces the meaning of space and time by moving the shape of the clothing or visually changing the surface of the material of clothing. As a result of the study, the non-representation shown in contemporary fashion aims for versatility to conform to social changes. This study provides new insight into the fashion design method by increasing the understanding of the cocnept of non-representation and showing its potential.

• Journal of the Korean Wood Science and Technology
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• 제31권2호
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• pp.58-68
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• 2003

목조 고건축물의 안전성 평가를 위해서는 먼저 부재의 성능평가가 선행되어야 한다. 지금까지의 목재 부재의 성능평가는 육안에 의한 경험적 방법에 의존하였다. 하지만 과학적이고 합리적인 비파괴 방법을 적용하여 구조부재의 성능을 평가할 수 있다면 구조물의 안전성 해석은 더욱 정확해지고 합리적이 될 것이다. 이를 위해 본 연구에서는 목조 고건축물의 여러 구조 부재 중 기둥에 대해 비파괴 평가법을 적용하여 구조부재의 성능 평가에 대한 가능성을 알아보았다. 이 결과를 이어지는 연구에서 구조물의 안전성 해석의 기초자료로 사용할 예정이다. 특별히 기둥의 노출 환경에 따른 열화의 진행정도를 비파괴 평가법으로 측정하였다. 그 결과 실제 육안에 의한 열화의 관찰과 유사한 결과를 나타내어 비파괴 방법의 적용 가능성을 보여주었다.

• 인터넷정보학회논문지
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• 제23권1호
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• pp.105-112
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• 2022

국방은 감염병과 같은 비전통 위협에 대한 직·간접적인 영향에서도 중단없는 의사결정 업무 수행이 필요하다. 모든 업무는 정보시스템을 활용하기에 정보시스템의 가용성을 보장하는 것이 매우 중요하다. 특히, 국방업무는 보안관리 측면에서 네트워크를 국방망과 상용인터넷망으로 이원화하여 수행되고 있다. 본 연구는 효과적인 국방정보체계 운용을 통해서 인터넷에서 수행되는 업무의 효율성과 보안의 효과성을 고려한 업무수행 방안을 제시하였다. 국방망과 상용인터넷이 연결되는 네트워크 접점을 최소화하고 다양한 업무 중 우선순위가 높은 것을 선정하여 효율적으로 운용하는 방안이 필요하디. 이를 위해 A기관을 대상으로 실제 사례를 조사하고 특성을 제시하였다. 본 논문에서 제시한 국방업무의 효과성을 향상하고 보안성을 보장하기 위한 대상 업무와 운용방안을 통해 감염병과 같은 비전통 위협에서도 업무수행의 가용성을 높일 수 있을 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.4137-4142
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• 2015

The zinc finger transcription factor EGR 1 has a role in controlling synaptic plasticity, wound repair, female reproductive capacity, inflammation, growth control, apoptosis and tumor progression. Recent studies mainly focused on its role in growth control and apoptosis, however, little is known about its role in epithelial-mesenchymal transition (EMT). Here, we aim to explore whether EGR 1 is involved in TGF-${\beta}1$-induced EMT in non-smallcell lung cancer cells. Transforming growth factor (TGF)-${\beta}1$ was utilized to induce EMT in this study. Western blotting, RT-PCR, and transwell chambers were used to identify phenotype changes. Western blotting was also used to observe changes of the expression of EGR 1. The lentivirus-mediated EGR 1 vector was used to increase EGR 1 expression. We investigated the change of migration to evaluate the effect of EGR 1 on non-small-cell lung cancer cells migration by transwell chambers. After stimulating with TGF-${\beta}1$, almost all A549 cells and Luca 1 cells (Non-small-cell lung cancer primary cells) changed to mesenchymal phenotype and acquired more migration capabilities. These cells also had lower EGR 1 protein expression. Overexpression of EGR 1 gene with EGR 1 vector could decrease tumor cell migration capabilities significantly after adding TGF-${\beta}1$. These data s howed an important role of EGR 1 in the EMT of non-small-cell lung cancer cells, as well as migration.

• Journal of Ginseng Research
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• 제16권3호
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• pp.228-234
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• 1992

There has been general tendency to explain the traditional ginseng efficacy through the pharmacological and biochemical activities of ginsenosides. However, when we analyze the pharmacological and biological data on ginseng reported yet, we can easily arrive at the conclsion that most of the data on pharmacological and biological activities must have been obtained using impure ginsenoside samples, which should contain some non-saponin constituents as impurities. Based on the above back-ground, the non-saponin constituents of ginseng were studied in our laboratory. Phenolic substances including Maltol, Vanillic Acid, Salicylic Acid, Ferrulic Acid and Caffeic acid and impure ginsenoside samples were found to show strong antioxidant and anti-fatigue activities, while pure ginsenosides were devoid of the activities. Maltol, one of antioxidant components In Korean red ginseng drew a special interest due to its very low pro-oxidant activity. The antioxidant activity of ginseng may be considered as scientific basis for the antiageing activity which was described in traditional medicinal material book as "long-term medication of ginseng will improve bio-efficiency and extend life-span" The lignin components, another non-saponin consitutents, isolated from ginseng extract In our laboratory may eplain the hepato-protective activity of ginseng which has been repeatedly rtaimed as one of the efficacies of ginsenosides. The P-carboline alkaloids isolated in our laboratory as one of the non-saponin constituents of ginseng may play some pharmacological activities which should also be investigated. Present paper will include chemistry and biochemical aspects of the non-saponin constituents of ginseng with special interests for the explanation of traditional ginseng efficacy on modern scientific basis.fic basis.

• 대한암한의학회지
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• 제17권1호
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• pp.39-43
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• 2012

Objective : This study reports one case of a patient diagnosed with squamous cell carcinoma of the lung cancer with bone metastasis. Methods : A 56-year old male patient was diagnosed as squamous cell lung cancer in 1997 and received chemotherapy. The chemotherapy stopped after one cycle because of toxicity and the lung abscess. After four months from the diagnosis, rib metastasis was found and received the radiation therapy for two weeks. After the treatment, adverse effects such as nausea and anorexia appeared. The patient visited K. Korean Medicine Hospital and started the treatment with the allergen removed Rhus verniciflua stokes (aRVS) since December, 1997. Results and Conclusion : During treatment, the patient's quality of life had improved, and he had survived for 14 years after the administration of aRVS. This case suggests that aRVS can be an alternative treatment for the advanced NSCLC patients with bone metastasis.

• Journal of the Korean Wood Science and Technology
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• 제36권1호
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• pp.21-29
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• 2008

서울시 내에 소재한 현재까지 이용되고 있는 목조건물에 대한 열화 조사를 실시하였다. 조사된 목조건물은 겨울철임에도 흰개미에 의한 피해가 진행되고 있었다. 목조건물의 흰개미 피해 실태 및 원인을 조사하기 위하여 초음파에 의한 비파괴 방법을 적용하였으며, 환경적 열화요인 조사에는 적외선 카메라를 사용하였다. 비파괴 검사를 통한 기둥부재의 내구성을 조사한 결과 일부 기둥 부재에서는 심각한 강도적 손실이 발견되어 교체가 필요하였다. 조사된 목조건물은 사람이 생활하기 위하여 현대식 난방설비를 설치한 곳으로서 전통적인 목조건물 내부에 난방시스템이 설치됨으로써 연중 비교적 균일한 온도대의 형성 그리고 바닥재에 의한 결로발생으로 인한 수분 제공이 흰개미의 피해가 발생되는 원인으로 작용하게 되었다. 조사한 목조건물의 흰개미는 일본흰개미, Reticulitermes speratus로 동정되었다. 목조건물은 주위환경에 따라서 많은 영향을 받으므로 환경 조절을 통하여 생물열화를 방지할 수 있는 유지 관리 기술이 필요하였다. 전통건물 내 현대식 시설의 설치는 전통목조건물의 특징을 잘 살리고 내구성에 영향이 없는 시설의 설치가 바람직하다고 판단되었다.

• 동의신경정신과학회지
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• 제28권3호
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• pp.217-230
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• 2017

Objectives: This study was conducted to review studies on somatization disorder in traditional Chinese medicine. Methods: We reviewed studies in the China National Knowledge Infrastructure (CNKI) to 2017. Keywords were 軀體化障碍, Somatization disorder, somatic symptom disorder. We included Randomized Controlled Trial (RCT), and excluded non-Randomized Controlled Trial (nRCT), non-related somatization disorder or traditional Chinese medicine, non-clinical trials, dissertations for degrees. Jadad scale and Cochrane Library's Risk of Bias (RoB) were used for assessment of the quality of studies. Results: Twelve studies were selected. The Chinese Classification of Mental Disorders-3 (CCMD-3) was most frequently used as diagnostic criteria for somatization disorder. As for outcome measurement, Hamilton Rating Scale for Depression (HAMD) was used most commonly. Meta-analysis of 10 studies revealed effective rate of Chinese Herbal Medicine groups (CHM) was significantly higher than Western Medicine groups (WM) (RR: 1.14, 95% CI: 1.02 to 1.27, p=0.02, $I^2=40%$). There was no significant difference in effective rate of CHM+WM and WM (RR: 1.12, 95% CI: 0.84 to 1.49, p=0.46, $I^2=83%$). And also, effective rate of Acupuncture group (Acu) revealed no significant difference compared to that of WM (RR: 1.17, 95% CI: 0.95 to 1.44, p=0.13, $I^2=84%$). For HAMD, there was significant difference in CHM vs, WM group and Acu vs. WM group. Quality of selected 12 RCTs was low. Conclusions: Therapies practiced in traditional Chinese medicine may be effective options for somatization disorder. treatment. For further clinical studies in Korean medicine, this study could be groundwork for development of diagnosis and treatment on somatization disorder.

• 셀메드
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• 제4권2호
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• pp.10.1-10.8
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• 2014

Affecting more than half of menstruating women, dysmenorrhea is a cramp which causes abdominal or lower back pain just before or during a menstruation. In western medicine, non-steroidal anti-inflammatory drugs (NSAIDs) are normally used to treat primary dysmenorrheal symptoms. Despite their rapidity in relieving pain, NSAIDs have many serious side effects on the liver, kidney, and gastrointestinal tract. Thai traditional medicines comprise many preparations for treating dysmenorrhea, especially Prasaplai preparation which has been listed in the Thai traditional common household drug list since 2006. The use of Prasaplai was originated about 100 years ago and is still being used in the present time to treat dysmenorrhea. This review focuses on the history of the preparation, active ingredients, and biological activities especially on cyclooxygenase inhibitor, artifacts occurred in the preparation, quantitative analysis, and clinical trial of Prasaplai formulation.

• 대한음성학회:학술대회논문집
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• 대한음성학회 1996년도 10월 학술대회지
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• pp.367-371
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• 1996

Most Koreans agree that Korean traditional singing voice has a very peculiar sound comparing to Western singing voice. The goal of this paper is to investigate the acoustic characteristics of Korean traditional singing voice called 'Pansori' Materials are analyzed from 3male professional singers and 4 female professional singers. Their singing was compared with their own conversation and other non-singers' conversation. Long term average spectra indicated that all the singers showed a much less spectral tilt than non-singers. The phenomenon was prevailing for professional singers not only in their singing, but also in their conversation. This suggests that it is not the result of a temporary effort but it may involve a certain permanent change in their physiological configuration. (To assess this hypothesis, voice source should be looked at directly. Therefore, in further research, using Rothenberg mask (Rothenberg, 1973) is strongly recommended.) In addition to LTA, individual vowel formants will be studied later.