• Journal of Marine Bioscience and Biotechnology
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• v.15 no.2
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• pp.96-102
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• 2023

Salicornia herbacea, a noted halophyte, has been widely researched for its diverse physiological activities. The continuous exploration of its compounds is essential. This study employed gas chromatography (GC) coupled with mass spectrometry (MS) for qualitative analysis. This involved pretreatment including trimethylsilyl (TMS) derivatization of the S. herbacea extract, facilitating its GC analysis. Five compounds, including various fatty acids and β-sitosterol, were identified by direct analysis of the methanol extract of S. herbacea without pretreatment by GC-MS. Conversely, the analysis of the TMS-derivatized extract revealed 28 distinct peaks. Quantitative analysis further indicated that the predominant compounds in the S. herbacea extract were sugars and sugar derivatives, notably glucose, fructose, and glucitol. The collective concentration of these sugars and its derivatives amounted to 116.45 mg/g, representing 11.6% of the dry weight of the raw S. herbacea. Following sugars and their derivatives, fatty acids constituted the next most abundant group of compounds. However, the presence of amino acids and organic acids was relatively low.

• Health Policy and Management
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• v.30 no.3
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• pp.345-354
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• 2020

Background: This study purposed to examine the difference in the prevalence of obesity at each stage among people with and without disabilities considering the severity and type of disability. Methods: The study targeted a total of 1,315,967 people, including 68,418 disabled and 1,247,549 non-disabled, who completed the national health screenings. Logistic analysis and average marginal effect analysis were conducted in three stages (pre-obesity, obesity, severe obesity). Those analyses were conducted considering the severity and type of disabilities. Results: People with disabilities were more likely to be at all stages of obesity than non-disabled people. In severely disabled people, the probability of obesity was higher than non-disabled people at all stages of obesity, but mildly disabled people had a higher only in the severe obesity stage, no difference in obesity stage, and a low in the pre-obesity stage. In physical and mental disabilities, the probability of obesity was higher than non-disabled people at all stages of obesity, but external physical function and internal organs disabled had a lower in the obesity and pre-obesity stage, and no difference in severe obesity stage. Conclusion: This study found that people with disabilities had a higher relationship with obesity than people without disabilities. In addition, severity and types of disabilities have different effects on the stage of obesity. Therefore, it is necessary to care about the health inequality and health of disabled people considering their severity and types of disabilities.

• Journal of Korean Society of Forest Science
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• v.104 no.2
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• pp.319-331
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• 2015

The marketing system of non-timber forest products has been criticized as it mainly depends upon private local dealers, having too many steps between producers and consumers, we believe, which makes it less efficient. Meanwhile, there were only a few empirical studies of how they are delivered to consumers. In order to devise and implement targeted forest policies efficiently, it is quite necessary to understand the distribution channel of them. We analyzed the distribution channel of chestnut, bitter persimmon, oak mushroom, and wild greens by data analysis, field and phone survey, and then drew an implication for improving the marketing system. First of all, the number of middle step has to be reduced and the direct transaction has to be expended. In addition, we need to have more active involvement of Forest cooperative in production sites, adding values by processing, and the upgrade of current marketing centers of non-timber forest products, which have been launched since 2004 by Korea Forest Service.

• Analytical Science and Technology
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• v.36 no.1
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• pp.22-31
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• 2023

As the use of e-liquid cigarettes is rapidly increasing worldwide, it multiplies the potential risk undisclosed to the health of non- and smokers. To reduce the hazard, each country has its own set of regulations for controlling e-liquids. In Korea, the narrow definition of tobacco makes it difficult and have been steadily occurring tax evasion exploiting the difference in natural and artificial nicotine. Therefore, it is very important to distinguish source of nicotine for their regulation. To find biochemical discriminant markers, this study established analysis methods based on high-performance liquid chromatography coupled with diode array detector (HPLC-DAD) and high-performance liquid chromatography coupled with triple Quadrupole mass spectrometry (HPLC-MS/MS) for nicotine enantiomers and tobacco alkaloids targeted using the difference in pathways of nicotine biosynthesis and chemical synthesis. The method was validated by experimenting linearity (R² > 0.999), recovery (80.99-108.41 %), accuracy (94.11-109.73 %) and precision (0.04-8.27 %). Then, the results for discrimination of the nicotine obtained from analysis of 65 commercial e-liquid products available in Korean market was evaluated. The method successfully applied to the e-liquids and one sample labelled 'synthetic nicotine' for tax exemption was found to contain a natural nicotine product. This method can be used to determine whether an e-liquid product uses natural or artificial nicotine and monitor non-taxable e-liquid products. The method is more scientific than the existing one, which relies only on field evidence.

• Journal of dental hygiene science
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• v.19 no.1
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• pp.48-59
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• 2019

Background: The purpose of this study is to provide the data for discussions related to oral health promotion policies for single-person households by analyzing the status of unmet dental needs and related factors in single-person households in Korea, based on the Anderson model. Methods: The data, obtained from 544 single-person households of those over 20 years old who were targeted for the 6th Korea National Health and Nutrition Examination Survey, were analyzed through a complex sample frequency analysis, complex sample cross analysis (Rao-Scott chi-square test), and complex sample binary logistic regression analysis on a complex sampling design. Results: The most frequently given reason for an unmet dental need among single-person households was economic (52.4%). Factors related to the unmet dental needs of single-person households are smoking, which is a predisposing factor; personal income levels, which are an enabling factor; chewing discomfort; and limited daily activities, which are need factors. Smokers, the high-income group, the chewing-discomfort group, and the limited activity group showed high unmet dental care experience. Smokers had a 2.75 times higher rate of unmet dental care than non-smokers, and the high-income group had a 5.29 times higher rate of unmet dental needs than the median group. The rate of unmet dental needs for the chewing discomfort group was 3.27 times higher than the non-chewing discomfort group, and the limited activity group had a 7.87 times higher rate of unmet dental needs than the non-limited activity group. Conclusion: It is necessary to map out policies designed to help maintain and promote met dental needs considered to be internally heterogeneous to single-person householders, based on the Anderson model.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.17 no.2
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• pp.69-76
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• 2017

Citrin deficiency is an autosomal recessive disorder caused by mutations in the SLC25A13 gene on chromosome 7q21.3, and a type of urea cycle disorder that causes hyperammonemia. Although neonatal intrahepatic cholestasis and adult-onset type II citrullinemia, a type of citrin deficiency, have been described well in many articles for several decades, failure to thrive and dyslipidemia caused by citrin deficiency (FTTDCD), the other type of citrin deficiency, has been only identified recently. There was previously no case report about FTTDCD in Korea. Patients with FTTDCD could present with loss of appetite, fatigue, failure to thrive, hypoglycemia, hypercitrullinemia, dyslipidemia, and an increased lactate/pyruvate ratio. Routine evaluation may not reveal the cause of hypoglycemia caused by citrin deficiency. We recently had a case that presented with recurrent hypoglycemia in a 30-month-old boy. Chemistry profiling, urine organic acid analysis, plasma acylcarnitine analysis, and hormone studies indicated values within the normal range or non-specific findings. Mutation analysis to identify the cause of hypoglycemia identified the subject as a compound heterozygote carrying each of the c.852_855del ($p.Met285Profs^*2$), and c.1177+1G>A mutant alleles. We report here on this unusual case of citrin deficiency presenting with FTTDCD for the first time in Korea.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2000.10a
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• pp.211-214
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• 2000

The paper presents a case study with application of a performance measurement questionnaire in analyzing a semi-conductor-related manufacturing company. The case may contribute to the development of strategic performance measurement system. The questionnaire contains considerable non-financial measurement indices as well as financial ones, which may strengthen the strategic aspect of measurement system. The strategy, actions, and measures have to be balanced through communication process in an organization. The result shows the usefulness of the congruence and consensus analysis of performance factors in effectively managing strategic action programs and identifying investment task areas to be targeted.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.84-84
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• 2013

FcBP consisting of 13 amino acids specifically binds to Immunoglobulin G Fc domain. Initially, we utilized this peptide for preparation of antibody chip as a PEG composite for enhanced solubility. After then, the peptide conjugate was immobilized on agarose resin, resulting in highly efficient affinity column for antibody purification. The efficiency was comparable to commercial Protein A column. Recently, this peptide was conjugated with cell penetratingpeptide (CPP) on a backbone of GFP, affording antibody transducer, which carries antibody into live cells by simple mixing of antibody and the transducer in cell culture media. Antibody transduction into cells was monitored by live cell imaging. More recently, the FcBP was fused to ferritin cage, which consists of 24 ferritin protein molecules. The FcBP-ferritin cage showed greatly increased binding affinity to human IgG. Its binding was analyzed by QCM and SPR analysis. Finally, it was selectively delivered by Herceptin to SKBR3, a breast cancer cell, over MCF10A, non-tumorigenic cells.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.44.1-44.1
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• 2021

The Cosmic Microwave Background (CMB) contains a wealth of information about the perturbations in the early universe. Its bispectrum, the Fourier counterpart of three-point correlation functions, is a direct probe of primordial non-Gaussianity predicted by many physically well motivated inflation models. Motivated by the substantial improvement in sensitivity expected from future CMB surveys, we developed a novel bispectrum estimator capable of handling such high-resolution data. Our code, named CMB-BEst, utilises a set of separable basis functions to constrain a wide variety of models simultaneously. Flexibility in the choice of basis enables targeted analysis on highly oscillatory inflation models, which are previously unconstrained due to the numerical and computational challenges involved. We present the results of our thorough validation tests, both internal and against conventional approaches. We provide a proof-of-concept example with Planck satellite data and sketch out the road ahead.

• Journal of the Korean Society for Nondestructive Testing
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• v.24 no.5
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• pp.525-531
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• 2004

In this paper, the concept of infrared thermography(IRT), the principle of measurement of IRT and how to set up the IR camera for the nondestructive testing are described in detail. Also, its utilization and non-destructive testing(NDT) diagnosis are reviewed. By performing the periodic non-touched WDT through the estimation of thermal patterns related with the temperature for the surface targeted, IRT can be applied to the early prevention of the device failure. For the diagnosis utilization, thermal imaging patterns obtained from IRT for heated blocks with internal defects were estimated through the lion-destructive method and discussed the way of IRT estimation from the analysis of characteristics between material defects and thermal imaging patterns.