• 한국체육학회지인문사회과학편
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• v.55 no.2
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• pp.603-615
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• 2016

This study was conducted by performing intensities aerobic exercise for 12 weeks, three times a week targeting 28 middle aged women. The purpose of this study was analyzing factors which affect cognitive function and changes of blood pressure, renin-aldosterone system, neurotransmitter, cognitive function and working memory after treatment. The participants were divided into three groups which are the control group(n=9, non exercise), moderate intensity aerobic exercise group(n=10, 50%V02max), high intensity aerobic exercise group(n=9, 70%V02max). The two-way ANOVA(repeated measure) and multiple regression analysis were carried out to target those three groups before and after treatment. The results were as follows like this. The moderate intensity aerobic exercise increased renin, brain derived neurotrophic factor(BDNF), cognitive function and working memory. Also, it reduced aldosterone, angiotensinII and aldosterone-renin ratio. The high intensity aerobic exercise showed increase BDNF, cognitive function and working memory and decrease systolic. As a result of a multiple regression analysis of factors affecting cognitive function after intensities aerobic exercise, the moderate intensity aerobic exercise affected diastolic blood pressure, decrease of aldosterone-renin ratio and working memory. Also, an increase of BDNF affected cognitive function, the high intensity aerobic exercise affected working memory BDNF and an increase of serotonin affected cognitive function. Therefore, It could be seen that more than moderate intensity exercise increase woman's cognitive function and working memory. Also, there were metabolic factors which affect the increase of cognitive function. To moderate intensity exercise, renin-aldosterone and working memory affected to increase of cognitive function. For high intensity exercise, BDNF and working memory affected to it.

• 한국체육학회지인문사회과학편
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• v.55 no.5
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• pp.593-604
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• 2016

The purpose of this study was to examine the effect of teaching behaviors perceived by college students' participating in liberal dance classes on learning motivation and continuous participation intention. The main target audience of this research is college students who participate in liberal dance classes in five universities in Seoul and Gyeonggi. By using purposive sampling among non probability sampling, totally 330 papers had been distributed, and 314 questionnaires had been used for practical analysis. The data process was performed by frequency analysis, exploratory factor analysis, confirmatory factor analysis, reliability analysis, structural equation modeling. The results were as follows: First, teaching behaviors perceived by college students' participating in liberal dance classes had a significant effect on learning motivation. Secondly, teaching behaviors perceived by college students' participating in liberal dance classes had a significant effect on continuous participation intention. Lastly, learning motivation perceived by college students' participating in liberal dance classes had a significant effect on continuous participation Intention. Lastly, there was the mediating effect of learning motivation was inspected in the relationship between teaching behaviors perceived by college students' participating in liberal dance classes and continuous participation intention.

• Phonetics and Speech Sciences
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• v.15 no.2
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• pp.1-11
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• 2023

This study investigated the response time and patterns of categorical perception of the wh-scope of an embedded clause with the non-bridge verb, "gung-geum hada 'wonder'," in the matrix verb phrase in Gyeongsang Korean. Using the same procedure as Yun (2022), 72 responses and response times for each stimulus were collected from 24 participants over the course of three trials. The stimuli were recorded readings of 40 speakers (20 male, 20 female). Context was provided to induce a matrix scope interpretation of the embedded wh-phrase in the target sentence. We sorted the 40 stimuli according to the number of matrix scope responses each received, and charted the response times for each stimulus. Although there was considerable overlap for the different types of wh-scope interpretations, there was a clear difference in categorical perception between the matrix and embedded scopes. The 24 participants also differed in their categorical perceptions. The results suggested that response time and wh-scope interpretation were not directly related and that two main weighted factors affected wh-scope interpretation: morpho-syntactic constraints and prosodic structural integrity. The weighting of each of these factors was inversely correlated and varied among subjects.

• The Korean Journal of Franchise Management
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• v.3 no.1
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• pp.1-25
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• 2012

The studies of franchise companies are underway with the development of the franchise industry. Franchisor performance, franchisee performance, and relationship characteristics on performance, financial performance, non-financial performance, including research on the topic or purpose of the franchise performance and related discussions from a variety of perspectives have been proposed. Presented so comprehensive a discussion regarding the existing performance of the franchise and qualitative aspects such as satisfaction, long-term orientation to emphasize the limits. Therefore, this study was conducted by the franchise company's performance than the need to be clearly presented. Propose a quantifiable and quantified to reflect the characteristics of the franchise quantitative performance indicators. Franchise contract management systematically analyze the status of the enterprise contract management(ECM) and proposed contract management, leverage as an indicator for a more quantitative analysis. Contract management leverage is the franchise as an indicator of the merchant and the growth of the contract showing any significant changes in the coming changes in the Franchisee's sales growth target analysis results, notable implications could be found. This study are new methodology for the practical dimensions of performance of franchise companies.

• Journal of Convergence for Information Technology
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• v.12 no.2
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• pp.1-16
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• 2022

Social network service (SNS) using mobile or web is growing rapidly, and the emergence of various platform services is causing innovative changes in social network service (SNS). This study is to identify the target relation factors of social network users and to empirically study the causal relationship of how much these factors affect user satisfaction through pleasure and self-efficacy. To present an effective and efficient development plan in. In order to empirically verify the research model of this study, a survey was conducted with the general public who had experience using social network services (SNS). Path analysis was performed. As a result, it was possible to verify the correlation of the object relational factors on user satisfaction through pleasure and self-efficacy.First, non-excluded had a significant effect on pleasure, but did not significantly affect self-efficacy. Second, stability attachment did not significantly affect both enjoyment and self-efficacy. Third, social ability did not significantly affect both enjoyment and self-efficacy. Fourth, self-centeredness did not have a significant effect on both enjoyment and self-efficacy. Fifth, pleasure had a significant effect on both self-efficacy and user satisfaction. Sixth, self-efficacy had a significant effect on user satisfaction.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.170-170
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• 2022

Grain filling traits of rice were traced to determine the critical temperature that ceased grain filling process, from the late transplanted temperate rice varieties in the field conditions of2020 and 2021. The tested three varieties were transplanted six times with four target heading dates of 20 Aug. (control), 10 Sep., 20 Sep. and 30 Sep. Nine times of sampling were made from a week after heading with three replicates for each treatment. Development of grain filling percentage, grain dry weight and milled rice weight demonstrated sigmoid curves in the first and second transplants of 2020, and in the first to third transplants of 2021. The three grain filling traits in the 2020 third transplants and in the 2021 fourth transplants initially increased with the progress of grain development, and reached the peaks at certain time points, then decreased thereafter. Non-linear regression analyses, performed for the traits in the transplants that showed sigmoid curves except control, indicated that 95% of the final data (95% FD) was attained when the seven-day moving temperature (Sd-MovT) was 8.4-9.6℃, which excluded the cases when the temperature before the dates of 95% FD was lower than that on the dates of 95% FD. Sd-MovT on the date of peak data was 8.5-9.8℃ in the 2020 third transplants and 6.9-8.3℃ in the 2021 fourth transplants. Grain development was observed when seven-day mean temperature (Sd-MT) from 35 to 41 days after heading date was 9.4-10.8℃ in the 2020 third transplants and 10.1-11.9℃ in the 2021 fourth transplants. But Sd-MT of 8.7-9.1℃ in 2020 and 6.9-7.6℃ in 2021, at 42-48 days after heading, resulted in no progress of grain development. Overall, Sd-MovT at the point of stagnated grain development appeared in the range of 6.9-9.8℃. The lowest Sd-MT that showed the progress of grain development was 9.4-9.5℃ and the highest Sd-MT that showed no grain development was 9.1℃, both of which appeared in Odae and Haiami of the 2020 third transplants Therefore it is concluded that critical temperature for the grain development of temperate rice in natural conditions exists between 9.1℃ and 9.5℃.

• Nutrition Research and Practice
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• v.17 no.5
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• pp.899-916
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• 2023

BACKGROUND/OBJECTIVES: Oxidative stress is a fundamental neurodegenerative disease trigger that damages and decimates nerve cells. Neurodegenerative diseases are chronic central nervous system disorders that progress and result from neuronal degradation and loss. Recent studies have extensively focused on neurodegenerative disease treatment and prevention using dietary compounds. Heseperetin is an aglycone hesperidin form with various physiological activities, such as anti-inflammation, antioxidant, and antitumor. However, few studies have considered hesperetin's neuroprotective effects and mechanisms; thus, our study investigated this in hydrogen peroxide (H₂O₂)-treated SH-SY5Y cells. MATERIALS/METHODS: SH-SY5Y cells were treated with H₂O₂ (400 µM) in hesperetin absence or presence (10-40 µM) for 24 h. Three-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assays detected cell viability, and 4',6-diamidino-2-phenylindole staining allowed us to observe nuclear morphology changes such as chromatin condensation and apoptotic nuclei. Reactive oxygen species (ROS) detection assays measured intracellular ROS production; Griess reaction assays assessed nitric oxide (NO) production. Western blotting and quantitative polymerase chain reactions quantified corresponding mRNA and proteins. RESULTS: Subsequent experiments utilized various non-toxic hesperetin concentrations, establishing that hesperetin notably decreased intracellular ROS and NO production in H₂O₂-treated SH-SY5Y cells (P < 0.05). Furthermore, hesperetin inhibited H₂O₂-induced inflammation-related gene expression, including interluekin-6, tumor necrosis factor-α, and nuclear factor kappa B (NF-κB) p65 activation. In addition, hesperetin inhibited NF-κB translocation into H₂O₂-treated SH-SY5Y cell nuclei and suppressed mitogen-activated protein kinase protein expression, an essential apoptotic cell death regulator. Various apoptosis hallmarks, including shrinkage and nuclear condensation in H₂O₂-treated cells, were suppressed dose-dependently. Additionally, hesperetin treatment down-regulated Bax/Bcl-2 expression ratios and activated AMP-activated protein kinase-mammalian target of rapamycin autophagy pathways. CONCLUSION: These results substantiate that hesperetin activates autophagy and inhibits apoptosis and inflammation. Hesperetin is a potentially potent dietary agent that reduces neurodegenerative disease onset, progression, and prevention.

• Journal of fish pathology
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• v.37 no.1
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• pp.111-122
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• 2024

This study assessed the impact of the toltrazuril derivative N-(4-(4-Fluorophenoxy)-3-methylphenyl) acetamide on natural cytotoxic cell (NCC) activity of olive flounder, Paralichthys olivaceus spleen. Five groups of fifteen olive flounder, comprising non-treatment and vehicle control groups, were randomly assigned. N-(4-(4-Fluorophenoxy)-3-methylphenyl) acetamide was injected intramuscularly at doses of 120, 150 and 200 mg/kg body weight; a total of ten injections were given over the course of 30 days. The NK activity of flounder splenic cells was evaluated against YAC-1, mouse lymphoma cells or HINAE cells with a choice of co-cultivation times of 4 or 18 hrs. In case of YAC-1 co-culture we observed a significant increase in cytotoxicity at a dose of 200 mg/kg, up to 3.06 times more than that of the control group. Only the trial with the 4 hrs co-culture produced a significant difference in the HINAE cell experiment; the experimental group at the 200 mg/kg dose exhibited the maximum cytotoxicity, demonstrating 2.3 times more cytotoxicity than the control group. Furthermore, the expression level of IL-12b was markedly induced in the group with 200 mg/kg, which was 6.62 times greater than that of the control group. In terms of the altered NK cell activity, the repeated high doses of N-(4-(4-Fluorophenoxy)-3-methylphenyl) acetamide can cause changes in the normal performance of immune function.

• Journal of the Korea Society of Computer and Information
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• v.29 no.4
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• pp.145-153
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• 2024

Through the 106th session of the International Maritime Organization(IMO)'s Maritime Safety Committee(MSC), a mandatory safety training requirement for all personnel transferred or accommodated for offshore industrial activities was established and adopted under the name of SOLAS Chapter XV, IP(Industrial Personnel) Code. This regulation mandates pre-boarding safety training to enable individuals to anticipate and mitigate hazardous risks in navigation and operational environments. Consequently, the IP Code includes provisions regarding the training content for industrial personnel and regulations for the refusal of master who has a full responsibility for individuals who have not completed the required training(non-qualified industrial personnel). Referred to as the IP Code, this agreement is set to enter into force in July 2024, necessitating the establishment and operation of safety education for industrial personnel boarding ships before that date. Accordingly, this paper reviews the legal requirements related to training within IP code and analyzes the details of models including training objectives, target audience, duration, and course structure of safety trainings such as STCW, OPITO, GWO training, and other delegated training related to current ships. Additionally, it aims to propose a curriculum model for IP training courses which consists of a total of 16 hours over 2 days, offered by the Korea Institute of Maritime and Fisheries Technology, including teaching objectives, duration, and course structure.

• Animal Bioscience
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• v.37 no.7
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• pp.1156-1167
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• 2024

Objective: MicroRNAs (miRNAs) are endogenous non-coding RNAs that can play a role in the post-transcriptional regulation of mammalian preadipocyte differentiation. However, the precise functional mechanism of its regulation of fat metabolism is not fully understood. Methods: We identified bta-miR-365-3p, which specifically targets the 3' untranslated region (3'UTR) of the FK506-binding protein 5 (FKBP5), and verified its mechanisms for regulating expression and involvement in adipogenesis. Results: In this study, we found that the overexpression of bta-miR-365-3p significantly decreased the lipid accumulation and triglyceride content in the adipocytes. Compared to inhibiting bta-miR-36 5-3p group, overexpression of bta-miR-365-3p can inhibit the expression of adipocyte differentiation-related genes C/EBPα and PPARγ. The dual-luciferase reporter system further validated the targeting relationship between bta-miR-365-3p and FKBP5. FKBP5 mRNA and protein expression were detected by quantitative real-time polymerase chain reaction and Western blot. Overexpression of bta-miR-365-3p significantly down-regulated FKBP5 expression, while inhibition of bta-miR-365-3p showed the opposite, indicating that bta-miR-365-3p negatively regulates FKBP5. Adenosine 5'-monophosphate (AMP)-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) signaling pathway is closely related to the regulation of cell growth and is involved in the development of bovine adipocytes. In this study, overexpression of bta-miR-365-3p significantly inhibited mRNA and protein expression of AMPK, mTOR, and SREBP1 genes, while the inhibition of bta-miR-365-3p expression was contrary to these results. Overexpression of FKBP5 significantly upregulated AMPK, mTOR, and SREBP1 gene expression, while inhibition of FKBP5 expression was contrary to the above experimental results. Conclusion: In conclusion, these results indicate that bta-miR-365-3p may be involved in the AMPK/mTOR signaling pathway in regulating Yanbian yellow cattle preadipocytes differentiation by targeting the FKBP5 gene.