• 한국경영과학회:학술대회논문집
• /
• 한국경영과학회 2004년도 추계학술대회 및 정기총회
• /
• pp.13-16
• /
• 2004

This paper deals with a one-searcher multi-target search problem where targets with different detection priorities move in Markov processes in each discrete time over a given space search area, and the total number of search time intervals is fixed. A limited search resource is available in each search time interval and an exponential detection function is assumed. The searcher can obtain a target detection award, if detected, which represents the detection priority of target and is non-increasing with time. The objective is to establish the optimal search plan which allocates the search resource effort over the search areas in each time interval in order to maximize the total detection award. In the analysis, the given problem is decomposed into intervalwise individual search problems each being treated as a single stationary target problem for each time interval. An associated iterative procedure is derived to solve a sequence of stationary target problems. The computational results show that the proposed algorithm guarantees optimality.

• 한국환경생태학회지
• /
• 제30권4호
• /
• pp.712-723
• /
• 2016

본 논문은 생명공학기술을 통해 생산된 LM벼에 대한 비표적 생물체 중 곤충을 중심으로 한 환경위해성 평가방법을 제시하고자 작성하였다. 자료조사를 위해 농업 해충관련 도감 및 서적을 활용하였고 참고문헌과 환경위해성 평가 관련 홈페이지를 참조하였으며, 논문이나 벼와 관련된 서적들을 통해 국내 현황을 참조하였다. 조사결과, 벼에 서식하는 곤충은 약 140여종으로 조사되었고, 초식성 곤충 분류군은 각각 수액섭식자, 곡물섭식자, 잎섭식자, 화분섭식자로 세분화하였다. LM벼에 피해가능성이 큰 비표적 곤충은 12종, 중간인 비표적 곤충은 28종, 경미한 비표적 곤충은 101종으로 조사되었으며, 바이러스를 매개하는 종은 11종, 잠재적 해충으로 분류되는 종은 9종으로 나타났다. 위해가설 가설적립단계 모식도를 작성하기 위하여 LM벼에 악영향을 받기 쉬운 곤충의 지리적 분포, 서식지의 특수화, 확산정도, 종풍부도 등을 이용하여 순위를 매겼으며, 10종(벼총채벌레, 애멸구, 벼멸구, 멸강나방, 혹명나방, 우리가시허리노린재, 먹노린재, 벼멸구붙이, 벼메뚜기, 벼잎굴파리)을 추려내었다. 이후 위해가설 가설정립단계 모식도를 작성하였으며 LM벼의 비표적 생물에 대한 영향을 추론하였다. 본 논문은 국내 자연생태계의 지속가능한 이용 및 보존에 기여하고, LMO의 환경위해성 평가, 심사를 통해 사전위해성을 차단할 수 있는 방법을 제시하고자 작성되었으며, 결과적으로 국민의 건강 및 생물다양성유지, 자연 생태계 보전을 위한 사후 안전관리 체계구축에 활용될 연구 자료를 제공하고자 한다.

• 한국농공학회논문집
• /
• 제49권3호
• /
• pp.79-88
• /
• 2007

This paper suggests a hierarchial method to select the target sites for the nonpoint source pollution management considering factors which reflect the interrelationships of significant outflow characteristics of nonpoint source pollution at given sites. The factors consist of land slope, delivery distance to the outlet, effective rainfall, impervious area ratio and soil loss. The weight of each factor was calculated by an analytic hierarchy process(AHP) algorithm and the resulting influencing index was defined from the sum of the product of each factor and its computed weight value. The higher index reflect the proposed target sites for nonpoint source pollution management. The proposed method was applied to the Baran HP#6 watershed, located southwest from Suwon city. The Agricultural Nonpoint Pollution Source(AGNPS) model was also applied to identify sites contributing significantly to the nonpoint source pollution loads from the watershed. The spatial correlation between the two results for sites was analyzed using Moran's I values. The I values were $0.38{\sim}0.45$ for total nitrogen(T-N), and $0.15{\sim}0.22$ for total phosphorus(T-P), respectively. The results showed that two independent estimates for sites within the test water-shed were highly correlated, and that the proposed hierarchial method may be applied to select the target sites for nonpoint source pollution management.

• 한국물환경학회지
• /
• 제31권3호
• /
• pp.286-294
• /
• 2015

Temporal and spatial characteristics of cyanobacterial communities at the monitoring stations for Harmful Algal Bloom Alert System (HABAS) in Nakdong River and Lake Dukdong were investigated for two years (2013 to 2014). A total of 30 cyanobacterial species from 14 genera were found at the survey stations. Microcystis sp. showed maximum cell density in the total cyanobacterial community in August, 2014 at ND-2 and in September, 2013 at ND-3 station. Lynbya limnetica and Geitlerinema sp., non-target species for alert criteria showed maximum cell density at ND-1 (August, 2013) and Dam station of Lake Dukdong (September, 2014), respectively. Total cyanobacterial cell density and the relative abundance of four target genera (Microcystis, Anabaena, Aphanizomenon and Oscillatoria spp.) for alert criteria was relatively lower in the mesotrophic Lake Dukdong than at the eutrophic riverine stations of Nakdong River, indicating cyanobacterial density and the RA of target genera is affected by the trophic state of the monitoring stations. Simulating the alert system using phycocyanin concentration as an alert criterion resulted in the longer period of alert issued compared to the period of alert issued using the current criterion of harmful cyanobacterial cell density due to the influence of phycocyanin concentration from non-target cyanobacterial species.

• 웰빙융합연구
• /
• 제5권2호
• /
• pp.43-50
• /
• 2022

Purpose: The small-scale environmental impact assessment conducted during the development project stage has focused on the preservation of the natural environment centered on non-urban areas, due to the nature of urbanization, health problems for citizens of high-density urban areas have a limitation in that they are relatively neglected. In the case of strategic environmental impact assessment and environmental impact assessment in urban areas, there is no basis for evaluation in urban areas because there are exceptions to be excluded from the target projects or there are no target project regulations for buildings. Therefore, in this research, we examined the problems with the target project such as the current environmental impact assessment, and tried to establish a system improvement plan that can solve them. Research design, data and methodology: After reviewing the current environmental impact assessment-related laws (including enforcement ordinances) and national land planning laws (including enforcement ordinances), exceptions such as environmental impact assessment in urban areas were identified and problems were identified. Based on this, an amendment to the Enforcement Decree was proposed to provide institutional support for the expansion of target projects such as environmental impact assessment in urban areas. Results and Conclusions: Through this research, it is expected that the projects subject to environmental impact assessment on development projects in urban areas directly related to the health of the people will be expanded, and the net function of the environmental impact assessment system will be maximized.

• Journal of Ginseng Research
• /
• 제47권2호
• /
• pp.291-301
• /
• 2023

Introduction: Non-small cell lung cancer (NSCLC) patients are particularly vulnerable to the Coronavirus Disease-2019 (COVID-19). Currently, no anti-NSCLC/COVID-19 treatment options are available. As ginsenoside Rg3 is beneficial to NSCLC patients and has been identified as an entry inhibitor of the virus, this study aims to explore underlying pharmacological mechanisms of ginsenoside Rg3 for the treatment of NSCLC patients with COVID-19. Methods: Based on a large-scale data mining and systemic biological analysis, this study investigated target genes, biological processes, pharmacological mechanisms, and underlying immune implications of ginsenoside Rg3 for NSCLC patients with COVID-19. Results: An important gene set containing 26 target genes was built. Target genes with significant prognostic value were identified, including baculoviral IAP repeat containing 5 (BIRC5), carbonic anhydrase 9 (CA9), endothelin receptor type B (EDNRB), glucagon receptor (GCGR), interleukin 2 (IL2), peptidyl arginine deiminase 4 (PADI4), and solute carrier organic anion transporter family member 1B1 (SLCO1B1). The expression of target genes was significantly correlated with the infiltration level of macrophages, eosinophils, natural killer cells, and T lymphocytes. Ginsenoside Rg3 may benefit NSCLC patients with COVID-19 by regulating signaling pathways primarily involved in anti-inflammation, immunomodulation, cell cycle, cell fate, carcinogenesis, and hemodynamics. Conclusions: This study provided a comprehensive strategy for drug discovery in NSCLC and COVID-19 based on systemic biology approaches. Ginsenoside Rg3 may be a prospective drug for NSCLC patients with COVID-19. Future studies are needed to determine the value of ginsenoside Rg3 for NSCLC patients with COVID-19.

• 한국지리정보학회지
• /
• 제23권3호
• /
• pp.174-191
• /
• 2020

본 연구에서는 대청호 상류에 있는 서화천 유역에서 부하지속곡선을 통한 소유역별 비점오염원 취약지역 및 관리 오염물질과 관리 시기를 분석하였다. 먼저 부하지속곡선을 만들기 위하여 장기 유출 모형인 SWAT를 구축하여 유량지속곡선(Flow Duration Curve)을 작성하였으며 그 결과에 목표 수질을 곱하여 부하지속곡선(Load Duration Curve)을 작성하였다. 목표 수질은 서화천 비점오염원 관리를 위해 지난 2017년 11월부터 측정한 모니터링 자료를 사용하였으며 측정자료의 60분위에 해당하는 값을 목표 수질로 설정하였다. 이때 산정된 값이 하천 생활환경 기준의 "약간좋음"(II)을 초과할 경우 목표 수질을 "약간 좋음"(II)으로 제한하였다. 비점오염원 취약지역은 목표 수질을 초과하는 초과율을 이용하여 선정하였으며 초과 되는 오염물질을 관리 물질로 판단하고 계절별 평가를 통해 관리시기를 선정하였다.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2012년도 제43회 하계 정기 학술대회 초록집
• /
• pp.151-151
• /
• 2012

A new plasma process, i.e., the combination of PIII&D and HIPIMS, was developed to implant non-gaseous ions into materials surface. HIPIMS is a special mode of operation of pulsed-DC magnetron sputtering, in which high pulsed DC power exceeding ~1 kW/$cm^2$ of its peak power density is applied to the magnetron sputtering target while the average power density remains manageable to the cooling capacity of the equipment by using a very small duty ratio of operation. Due to the high peak power density applied to the sputtering target, a large fraction of sputtered atoms is ionized. If the negative high voltage pulse applied to the sample stage in PIII&D system is synchronized with the pulsed plasma of sputtered target material by HIPIMS operation, the implantation of non-gaseous ions can be successfully accomplished. The new process has great advantage that thin film deposition and non-gaseous ion implantation along with in-situ film modification can be achieved in a single plasma chamber. Even broader application areas of PIII&D technology are believed to be envisaged by this newly developed process. In one application of non-gaseous plasma immersion ion implantation, Ge ions were implanted into SiO2 thin film at 60 keV to form Ge quantum dots embedded in SiO2 dielectric material. The crystalline Ge quantum dots were shown to be 5~10 nm in size and well dispersed in SiO2 matrix. In another application, Ag ions were implanted into SS-304 substrate to endow the anti-microbial property of the surface. Yet another bio-application was Mg ion implantation into Ti to improve its osteointegration property for bone implants. Catalyst is another promising application field of nongaseous plasma immersion ion implantation because ion implantation results in atomically dispersed catalytic agents with high surface to volume ratio. Pt ions were implanted into the surface of Al2O3 catalytic supporter and its H2 generation property was measured for DME reforming catalyst. In this talk, a newly developed, non-gaseous plasma immersion ion implantation technique and its applications would be shown and discussed.

• 농업과학연구
• /
• 제48권4호
• /
• pp.875-890
• /
• 2021

In order to confirm the safety of a genetically modified organism (GMO), we assess its potential toxicity on non-target insects and spiders. In this study, the effects of GM soybean, a type of vitamin-A-enhanced transgenic soybean with tolerance to the herbicide glufosinate, were assessed under a field condition. The study compared this vitamin-A-enhanced transgenic soybean and a non-GM soybean (Gwangan) in a living modified organism (LMO) isolated field of Kyungpook National University (Gunwi) and the National Institute Agricultural Sciences (Jeonju) in the Republic of Korea in 2019 - 2020. In total, 207,760 individual insects and arachnids, representing 81 families and 13 orders, were collected during the study. From the two types of soybean fields, corresponding totals of 105,765 and 101,995 individuals from the vitamin-A-enhanced transgenic soybean and Gwangan samples areas were collected. An analysis of variance indicated no significant differences (p < 0.05). A multivariate analysis showed that the dominance and richness outcomes of plant-dwelling insects were similar. The data on insect species population densities were subjected to a principal component analysis (PCA) and an orthogonal partial least squares-discriminant analysis (OPLS-DA), which did not distinguish between the two varieties, i.e., the vitamin-A-enhanced transgenic soybean and the non-GM soybean in any cultivated field. However, the results of the PCA analysis could be divided overall into four groups based on the yearly survey areas. Therefore, there was no evidence for the different impact of vitamin A-enhanced transgenic soybean on the above-ground insects and spiders compared to non-GM soybean.

• 환경영향평가
• /
• 제20권1호
• /
• pp.71-78
• /
• 2011

This paper aims to assessing impact of reduction of non-point source pollution in the Bokha Stream watershed. The BASINS/HSPF model was calibrated and verified for water flow and water qualities using Total Maximum Daily Load 8days data from 2006 to 2007. Accuracy of the BASINS/HSPF models in simulating hydrology and water quality was compared and there were somewhat differences of statistical results, but water flow and water quality were simulated in good conditions over the study period. The applicability of models was tested to evaluate non-point source control scenarios to response hydrology and water quality in the Bokha stream using various measures which include BMPs approach and change of landuse. The evaluation of reduction of non-point source pollution was developed using load-duration curve. Despite strong reduction of non-point source, there are not satiated target quality at low flow season.