• Title/Summary/Keyword: Non-carrier

Search Result 417, Processing Time 0.027 seconds

The Analysis of Bone regenerative effect with carriers of bone morphogenetic protein in rat calvarial defects (백서두개골 결손부에서 BMP전달체의 골재생효과분석)

  • Jung, Sung-Won;Jung, Jee-Hee;Chae, Gyung-Joon;Jung, Ui-Won;Kim, Chang-Sung;Cho, Kyoo-Sung;Chai, Jung-Kiu;Kim, Chong-Kwan;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
    • /
    • v.37 no.4
    • /
    • pp.733-742
    • /
    • 2007
  • Bone morphogenetic proteins have been shown to possess significant osteoinSductive potential, but in order to take advantage of this effect for tissue engineering, carrier systems are essential. Successful carrier systems must enable vascular and cellular invasion, allowing BMP to act as a differentiation factor. The carrier should be reproducible, non-immunogenic, moldable, and space-providing, to define the contours of the resulting bone. The purpose of this study was to review available literature, in comparing various carriers of BMP on rat calvarial defect model. The following conclusions were deduced. 1. Bone regeneration of ACS/BMP, ${\beta}-TCP/BMP$, FFSS/BMP, $FFSS/{\beta}-TCP/BMP$, MBCP/BMP group were significantly greater than the control groups. 2. Bone density in the ACS/BMP group was greater than that in ${\beta}-TCP$, FFSS, $FFSS/{\beta}-TCP$ carrier group. 3. Bone regeneration in FFSS/BMP group was less than in ACS/BMP, ${\beta}-TCP/BMP$, MBCP/BMP group. However, New bone area of $FFSS/{\beta}-TCP/BMP$ carrier group were more greater than that of FFSS/BMP group. ACS, ${\beta}-TCP$, FFSS, $FFSS/{\beta}-TCP$, MBCP were used for carrier of BMP. However, an ideal carrier which was reproducible, non-immunogenic, moldable, and space-providing did not exist. Therefore, further investigation are required in developing a new carrier system.

Design of a 16-QAM Carrier Recovery Loop for Inmarsat M4 System Receiver (Inmarsat M4 시스템 수신기를 위한 16-QAM Carrier Recovery Loop 설계)

  • Jang, Kyung-Doc;Han, Jung-Su;Choi, Hyung-Jin
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.33 no.4A
    • /
    • pp.440-449
    • /
    • 2008
  • In this paper, we propose a 16-QAM carrier recovery loop which is suitable for the implementation of Inmarsat M4 system receiver. Because the frequency offset of ${\pm}924\;Hz$ on signal bandwidth 33.6 kHz is recommended in Inmarsat M4 system specification, carrier recovery loop having stable operation in the channel environment with large relative frequency offset is required. the carrier recovery loop which adopts only PLL can't be stable in relatively large frequency offset environment. Therefore, we propose a carrier recovery loop which has stable operation in large relative frequency offset environment for Inmarsat M4 system. The proposed carrier recovery loop employed differential filter-based noncoherent UW detector which is robust to frequency offset, CP-AFC for initial frequency offset acquisition using UW signal, and 16-QAM DD-PLL for phase tracking using data signal to overcome large relative frequency offset and achieve stable carrier recovery performance. Simulation results show that the proposed carrier recovery loop has stable operation and satisfactory performance in large relative frequency offset environment for Inmarsat M4 system.

Characteristic as a Gene Delivery System of Water Soluble Chitosan Conjugated with Cationic Peptide (양이온 펩타이드가 컨쥬게이트된 수용성 키토산의 유전자 전달체로서의 특성)

  • Kim, Young-Min;Kim, Ji-Ho;Park, Seong-Cheol;Park, Yung-Hoon;Jang, Mi-Kyeong
    • KSBB Journal
    • /
    • v.31 no.4
    • /
    • pp.300-311
    • /
    • 2016
  • Recently gene delivery has been designed newly using bioactive biomaterial and applied in the various field by many researchers. In this study, we proposed a new gene delivery system which has the capability of targeting effect in the specific tissue and remarkably enhanced transfection efficiency. We investigated $^1H-NMR$ spectroscopy, particle size analyzer and gel retardation to confirm the correct preparation of gene delivery. Also, we identified the hemo-compatibility of gene delivery by hemolysis assay, non-cytotoxicity by MTT test and transfection efficiency. The uptake mechanism of the gene carrier was confirmed using inhibitor agent such as sodium azide, indomethacin, quercetin, colchicine, and chloropromazine. As a results, it was identified that gene carrier prepared by in this study entered in the cell by the microtubule-dependent, energy-dependent and clathrin-mediated endocytosis pathway.

The Hydrogen Generation's Characteristics using Plasma Reactor of Multi-needle Electrode Type (다중침전극형 플라즈마 반응기를 이용한 수소발생 특성)

  • Park, Jae-Yoon;Kim, Jong-Seok;Jung, Jang-Gun;Goh, Hee-Seok;Park, Sang-Hyun;Lee, Hyun-Woo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.17 no.11
    • /
    • pp.1246-1251
    • /
    • 2004
  • This paper is investigated about the effect of carrier gas type and the humidity for generating hydrogen gas. The vibration of the water surface is more powerful with increasing applied voltage. In this experimental reactor which is made of multi-needle and plate, the maximum acquired hydrogen production rate is about 3500 ppm. In the experimental result of generating hydrogen gas by non-thermal plasma reactor, the rate of generating hydrogen gas is different with what kind of carrier gas is. We used two types of carrier gas, such as $N_2$ and He. $N_2$ as carrier gas is more efficient to generate hydrogen gas than He because $N_2$ is reacted with $O_2$, which is made from water dissociation. In comparison with water droplet by humidifier and without water droplet by humidifier, the generation of hydrogen gas is decreased in case of water droplet by humidifier. That is the result that the energy for water dissociation is reduced on water surface because a part of plasma energy is absorbed at the small water molecular produced from humidifier.

Variations of the hole injection efficiency with IGBT's collector structure (IGBT의 콜렉터 구조에 따른 홀 주입효율의 변화)

  • Choi, Byung-Sung;Chung, Sang-Koo
    • Proceedings of the KIEE Conference
    • /
    • 1999.07d
    • /
    • pp.1956-1958
    • /
    • 1999
  • The analysis of hole injection efficiency at the p+/n-drift layer junction in non-punchthrough IGBT structure is presented. This analysis takes into account carrier concentration variations by conductivity modulation. Good agreement between this analysis and simulation is found over a wide range of carrier lifetime and current density. The proposed analytical model of the hole injection efficiency as a function of collector width, collector concentration has been verified by device simulator, ATLAS.

  • PDF

Synthesis of Ceria Nanosphere by Ultrasonic Spray Pyrolysis

  • Kim, Jong-Young;Kim, Ung-Soo;Cho, Woo-Seok
    • Journal of the Korean Ceramic Society
    • /
    • v.46 no.3
    • /
    • pp.249-252
    • /
    • 2009
  • Nanocrystalline ceria particles were prepared by using the ultrasonic spray pyrolysis method. The prepared ceria particles were found to be spherical and non-agglomerated by the SEM and TEM analyses. It was found that carrier gas influences the size and morphology. It was found that the air stream of carrier gas results in porous agglomerated structure of ceria abrasives, whereas solid nano-sphere can be obtained in a more oxidizing atmosphere.

Polysilicon Thin Film Transistors on spin-coated Polyimide layer for flexible electronics

  • Pecora, A.;Maiolo, L.;Cuscuna, M.;Simeone, D.;Minotti, A.;Mariucci, L.;Fortunato, G.
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2007.08a
    • /
    • pp.261-264
    • /
    • 2007
  • We developed a non self-aligned poly-silicon TFTs fabrication process at two different temperatures on spin-coated polyimide layer above Si-wafer. After TFTs fabrication, the polyimide layer was mechanically released from the Si-wafer and the devices characteristics were compared. In addition self-heating and hot-carrier induced instabilities were analysed.

  • PDF

Chitosan and Its Derivatives for Gene Delivery

  • Lee, Knen-Yong
    • Macromolecular Research
    • /
    • v.15 no.3
    • /
    • pp.195-201
    • /
    • 2007
  • Non-viral vectors, including lipid- or polymer-based systems, have attracted much attention to date as a gene delivery vehicle, due to safety issues with viral vectors. Chitosan, a naturally existing cationic polymer, has shown great potential as a gene delivery carrier, as it has low immunogenicity and toxicity, excellent transcellular transport ability, and is relatively easy to chemically modify. This review summarizes and discusses the general features of chitosan and its applications as a delivery carrier of DNA and RNA.

Velocity Measurements of Slurry Flows in CMP Process by Particle Image Velocimetry (Particle Image Velocimetry 기법을 이용한 CMP 공정의 Slurry유동 분석)

  • Kim Mun-Ki;Yoon Young-Bin;Koh Young-Ho;Hong Chang-Gi;Shin Sang-Hee
    • Journal of the Korean Society for Precision Engineering
    • /
    • v.23 no.5 s.182
    • /
    • pp.59-67
    • /
    • 2006
  • Chemical Mechanical Polishing(CMP) in semiconductor production is characterized its output property by Removal Rate(RR) and Non-Uniformity(NU). Some previous works show that RR is determined by production of pressure and velocity and NU is also largely affected by velocity of flowfield during CMP. This study is about the direct measurement of velocity of slurry during CMP and whole flowfield upon the non-groove pad by Particle Image Velocimetry(PIV). Typical PIV system is modified adequately for inspecting CMP and slurry flowfield is measured by changing both pad rpm and carrier rpm. We performed measurement with giving some variation in the kinds of pad. The results show that the flowfield is majorly determined not by Carrier but by Pad in the case of non-groove pad.

Effect of Taekwondo Training on Physical Fitness and Growth Index According to IGF-1 Gene Polymorphism in Children

  • Lee, Bonghan;Kim, Kijin
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.19 no.4
    • /
    • pp.341-347
    • /
    • 2015
  • This study analyzed the effect of regular Taekwondo training for 16 weeks on physical fitness and growth index depending on different IGF-1 gene polymorphisms. The subjects of the study were 44 male students who were 8 year years old. The IGF-1 gene showed the highest frequency of 18 CA repeat (190 bp) in 50% of subjects, and was found in the homozygote (n=11), heterozygote (n=22) and non-carriers (n=11). The results of the physical fitness and growth index among the gene polymorphism groups indicated no significant differences but the expected height of the non-carrier group was significantly high (p<0.05). After Taekwondo training, the homozygote group and the non-carrier groups demonstrated significant (p<0.05) increase in grip strength and in time in the standing with one leg while closing eyes test, respectively. Only the homozygote group had a significant (p<0.05) increase in thigh circumference. IGF-1 concentration significantly (p<0.05) increased in the heterozygote group, while HOMA-IR significantly (p<0.05) decreased in the homozygote group. Furthermore, there was a significant (p<0.05) decrease in glucose in both the homozygote and the non-carriers groups. The difference between physical fitness and growth index depending on the IGF-1 gene polymorphism after Taekwondo training did not show consistent impact.