• Journal of the Korean Society of Radiology
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• v.16 no.5
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• pp.639-647
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• 2022

This study analyzed the job characteristics of radiological technologists in charge of ultrasound examinations in the Yeongnam region. The measuring tool used in the study was a questionnaire, and the subjects were radiological technologists in charge of ultrasound examination at medical institutions located in the Yeongnam region from August 01 to November 30, 2021. In consideration of the COVID-19 situation, statistical analysis was performed using the SPSS/PC Ver 18.0 program using e-mail and SNS in a non-face-to-face manner with 158 questionnaires. As a result of analyzing the job characteristics of the radiological technologists in charge of ultrasound examination, the job satisfaction was 3.24±0.61. In the effect of job characteristic factors on job satisfaction, professional position, self-esteem, and trust relationship formation were found to be higher than the average of 3.0. However, as the dissatisfaction factor, compensation and appropriateness of work were cited. Therefore, in order to improve the job characteristics and satisfaction level of radiological technologists in charge of ultrasound examinations, it is necessary to do their best to improve the appropriate work environment of medical institutions and to continuously secure professionalism of radiological technologists in charge of ultrasound examinations.

• Korean Journal of Food Science and Technology
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• v.53 no.4
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• pp.408-415
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• 2021

This study was conducted to evaluate various beneficial functions of soaked and germinated Robusta coffee beans. Vietnam Robusta coffee beans were soaked in purified water or Salicornia extract for 12 h. The total polyphenol content of non-germinated coffee (NGC), Salicornia extract-germinated coffee (SGC), and water-germinated coffee (WGC) was found to be 16.71-20.17%. First, NGC, SGC, and WGC at concentrations of 25-100 ㎍/mL showed significant anti-oxidant effects on DPPH radical scavenging and xanthine oxidase activity. NGC, SGC, and WGC also inhibited tyrosinase activity and melanin formation in α-MSH-induced B16F10 cells. In addition, the anti-obesity property of germinated coffees was tested by the Oil Red O staining method. NGC, SGC, and WGC inhibited adipogenesis in 3T3-L1 cells without cytotoxicity. Taken together, germinated Robusta coffees with enhanced flavor showed beneficial multifunctional effects, such as anti-oxidant, anti-melanogenesis, and anti-adipogenesis effects.

• Journal of Conservation Science
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• v.37 no.6
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• pp.778-790
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• 2021

The Stone Seated Buddha Triad and Stone Standing Buddha in Bijung-ri are state-designated heritage (treasure) statues having the Buddha style of the Goryeo dynasty from the 6th century. Conservation scientific investigations were conducted to understand the preservation status of these stone Buddha statues and to establish a conservation plan. The Stone Seated Buddha Triad and Stone Standing Buddha are composed of fine-medium grained biotite granite, which is considered to be of the same origin owing to their low magnetic susceptibility distribution of less than 0.2 (×10^-3 SI unit) and similar mineral characteristics. The Stone Seated Buddha Triad has highly homogenous mineral composition and particle size, whole-rock magnetic susceptibility, and geochemical characteristics very similar to those of the nearby outcrop. It was confirmed that a combination of physical, chemical, and biological factors affects the Stone Buddha statues. In particular, both the Stone Seated Buddha Triad and Stone Standing Buddha tend to be chipped off from the front and cracked and scaled from the back. The Stone Standing Buddha located outdoors experiences granularity decomposition and black algae formation, which accelerate the weathering under unfavorable conservation environments. The result of non-destructive physical property diagnosis using ultrasonic velocity showed that both the Stone Seated Buddha Triad and Stone Standing Buddha have been completely weathered (CW), indicating very poor physical properties.

• Clean Technology
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• v.28 no.4
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• pp.301-308
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• 2022

Since nanoporous silica aerogel was first synthesized in 1931, its potential as an ultra-lightweight superinsulation material has been steadily attracting attention. Silica aerogel is the best thermal insulation material to date. However, the potential applications of this lightweight material have so far been hindered by its inherent fragibility and brittleness arising from its ultra-porous nature. Although the monolithic form of silica aerogel has the best ultra-lightweight superinsulation properties, it cannot be used in this form. Instead it is used in the form of powders, particles, and blankets. However, these forms still have shortcomings. Silica aerogel is most widely applied in the form of a fiber-reinforced aerogel blanket, but this form is likely to generate dust when handled. Although silica aerogel particles have been proven to be non-toxic to humans, dust formation remains a major barrier to the widespread application of silica aerogel blankets. This paper will investigate the unique properties of silica aerogel and determine what fields it can be used in or potentially be used in due to its unique properties. In addition, we will review the important advances in silica aerogel synthesis technology and its commercialization so far, and then consider the problems that exist for its widespread commercialization in the future and how to overcome them.

• BMB Reports
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• v.55 no.2
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• pp.98-103
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• 2022

Increased mRNA levels of cancer upregulated gene (CUG)2 have been detected in many different tumor tissues using Affymetrix microarray. Oncogenic capability of the CUG2 gene has been further reported. However, the mechanism by which CUG2 overexpression promotes cancer stem cell (CSC)-like phenotypes remains unknown. With recent studies showing that pyruvate kinase muscle 2 (PKM2) is overexpressed in clinical tissues from gastric, lung, and cervical cancer patients, we hypothesized that PKM2 might play an important role in CSC-like phenotypes caused by CUG2 overexpression. The present study revealed that PKM2 protein levels and translocation of PKM2 into the nucleus were enhanced in CUG2-overexpressing lung carcinoma A549 and immortalized bronchial BEAS-2B cells than in control cells. Expression levels of c-Myc, CyclinD1, and PKM2 were increased in CUG2-overexpressing cells than in control cells. Furthermore, EGFR and ERK inhibitors as well as suppression of Yap1 and NEK2 expression reduced PKM2 protein levels. Interestingly, knockdown of β-catenin expression failed to reduce PKM2 protein levels. Furthermore, reduction of PKM2 expression with its siRNA hindered CSC-like phenotypes such as faster wound healing, aggressive transwell migration, and increased size/number of sphere formation. The introduction of mutant S37A PKM2-green fluorescence protein (GFP) into cells without ability to move to the nucleus did not confer CSC-like phenotypes, whereas forced expression of wild-type PKM2 promoted such phenotypes. Overall, CUG2-induced increase in the expression of nuclear PKM2 contributes to CSC-like phenotypes by upregulating c-Myc and CyclinD1 as a co-activator.

• Membrane Journal
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• v.32 no.2
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• pp.150-162
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• 2022

In the field of water treatment and pharmaceutical bio an alumina hollow fiber membrane used for mixture separation. However, due to the lack of strengths it is very brittle to handle and apply. Therefore, it is necessary to study and improve the bending strength of the membrane to 100 MPa or more. In this study, as the mixing ratio of the nano-particles increased to 0, 1, 3, and 5 wt%, the viscosity of the fluid mixture increased. The pore structure of the hollow membrane produced by interrupting the diffusion exchange rate of the solvent and non-solvent during the spinning process suppresses the formation of the finger-like structure and gradually increases the ratio of the sponge-like structure to improve the membrane mechanical strength to more than 100 MPa. As a result, an interparticle space was ensured to improve the porosity of the sponge-like structure with high permeability, and it showed excellent N2 permeability of about 100000 GPU and high water permeability of 3000 L/m² h. Therefore, it can be concluded, that the addition of γ-Al₂O₃ nanoparticles as sintering aid is an important method to enhance the mechanical strength of the α-alumina hollow fiber membrane to maintain high permeability.

• Journal of Korea Entertainment Industry Association
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• v.13 no.2
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• pp.37-45
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• 2019

The This study aimed at clarifying that the cognitive interpretation code is essential for college students to read the correct culture while discussing the producer's story production system for creative advertising content and the process of interpreting the meaning of advertisers and the formation of principles and beliefs. The production of advertising content aimed at persuasion should first identify anachronistic reason system based on the target audience's perception principle. A concise analysis of the experiment found key clues that confirmed that a sample of the producer's intended story would be inconsistent with the clues of information that a college student could remember. I have tried to organize a semantic analysis tool that combines these key clues and as a tool for reading culture of the right time for college students. As a result, university student inmates were able to identify one side of positive communication: reading a new cognitive symbol culture based on their subjective experience and beliefs, rather than analyzing cross-sectional analysis of the primary language and non-verbal expressions of their advertising contents. In the future, if an advertising content story producer works to identify such a process in advance, it will help persuade inmates.

• Animal Bioscience
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• v.36 no.5
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• pp.710-719
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• 2023

Objective: The present study investigated whether protodioscin (PD), a steroidal saponin mainly found in rhizome of Dioscorea species, alleviates oxidative stress-induced damage of porcine oocytes during in vitro maturation. Methods: Oocytes were treated with different concentrations of PD (0, 1, 10, 100, and 200 µM) in the presence of 200 µM H₂O₂ during in vitro maturation. Following maturation, spindle morphology and mitogen-activated protein kinase activity was assessed along with reactive oxygen species level, GSH activity, and mRNA expression of endogenous antioxidant genes at the MII stage. On the day 7 after parthenogenetic activation, blastocyst formation rate was calculated and the quality of embryo and mRNA expression of development-related genes was evaluated. Results: Developmental competence was significantly poorer in the 0 µM PD-treated (control) group than in the non-treated (normal) and 10 µM PD-treated (10PD) groups. Although the reactive oxygen species level did not significantly differ between these three groups, the glutathione level and mRNA expression of antioxidant genes (superoxide dismutase 1 [SOD1], SOD2, nuclear factor erythroid 2-related factor 2 [Nrf2], and hemo oxygenase-1 [HO-1]) were significantly higher in the normal and 10PD groups than in the control group. In addition, the percentage of oocytes with defective spindle and abnormal chromosomal alignment was significantly lower and the ratio of phosphorylated p44/42 to total p44/42 was significantly higher in the normal and 10PD groups than in the control group. The total cell number per blastocyst was significantly higher in the 10PD group than in the control group. The percentage of apoptotic cells in blastocysts was highest in the control group; however, the difference was not significant. mRNA expression of development-related genes (POU domain, class 5, transcription factor 1 [POU5F1], caudal type homeobox 2 [CDX2], Nanog homeobox [NANOG]) was consistently increased by addition of PD. Conclusion: The PD effectively improves the developmental competence and quality of blastocysts by protecting porcine oocytes against oxidative stress.

• Journal of the Korean Geotechnical Society
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• v.26 no.11
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• pp.17-28
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• 2010

Vertical drains are commonly used to accelerate the consolidation process of soft soils, such as dredged materials, because they additionally provide a radial drainage path in a deep soil deposit. In practice, vertical drains are commonly installed in the process of self-weight consolidation of a dredged soil deposit. The absence of an appropriate analysis tool for this situation makes it substantially difficult to estimate self-weight consolidation behavior considering both vertical and radial drainage. In this paper, a new method has been proposed to take into account both vertical and radial drainage conditions during nonlinear finite strain self-weight consolidation of dredged soil deposits. For 1-D nonlinear finite strain consolidation in the vertical direction, the Morris (2002) theory and the PSDDF analysis are adopted, respectively. On the other hand, to consider the radial drainage, Barron's vertical drain theory (1948) is used. The overall average degree of self-weight consolidation of the dredged soil is estimated using the Carillo formula (1942), in which both vertical and radial drainage are assembled together. A series of large-scale self-weight consolidation experiments being equipped with a vertical drain have been carried out to verify the analysis method proposed in this paper. The results of the new analysis method were generally in agreement with those of the experiments.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.5B
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• pp.575-589
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• 2008

In the present work, we investigate the hydrodynamic behavior of a turbulent bore, such as tsunami bore and tidal bore, generated by the removal of a gate with water impounded on one side. The bore generation system is similar to that used in a general dam-break problem. In order to the numerical simulation of the formation and propagation of a bore, we consider the incompressible flows of two immiscible fluids, liquid and gas, governed by the Navier-Stokes equations. The interface tracking between two fluids is achieved by the volume-of-fluid (VOF) technique and the M-type cubic interpolated propagation (MCIP) scheme is used to solve the Navier-Stokes equations. The MCIP method is a low diffusive and stable scheme and is generally extended the original one-dimensional CIP to higher dimensions, using a fractional step technique. Further, large eddy simulation (LES) closure scheme, a cost-effective approach to turbulence simulation, is used to predict the evolution of quantities associated with turbulence. In order to verify the applicability of the developed numerical model to the bore simulation, laboratory experiments are performed in a wave tank. Comparisons are made between the numerical results by the present model and the experimental data and good agreement is achieved.