• Journal of the Korean Society of Radiology
• /
• v.84 no.6
• /
• pp.1391-1396
• /
• 2023

Malignant lymphoma has various pulmonary manifestations on chest CT, including nodules, masses, areas of consolidation, and ground-glass opacity. These presentations can pose a diagnostic challenge, as they mimic other disease patterns. Herein, we report a case of diffuse large B-cell lymphoma (DLBCL) manifesting as miliary nodules in a 67-year-old male initially presenting with dyspnea and fever. Radiologic findings included diffuse, bilateral, multiple tiny nodules consistent with metastasis, miliary tuberculosis, and fungal infection. However, further investigations, including laboratory tests, imaging, and biopsies, led to the diagnosis of DLBCL involving the lungs. Herein we reported a rare case of lymphoma involvement of the lung presenting as miliary nodules. Accurate diagnosis relies on a comprehensive evaluation of the clinical history, physical features, laboratory test results, and imaging findings.

• Nuclear Medicine and Molecular Imaging
• /
• v.40 no.3
• /
• pp.163-168
• /
• 2006

Purpose: Incidence of lung canter in patients with idiopathic pulmonary fibrosis (IPF) is known to be higher than that in general population. However, it is difficult to discriminate pulmonary nodule in patients with IPF, because underlying IPF can be expressed as lung nodules. We evaluated the diagnostic performance of FDG PET in discriminating lung nodule in patients with IPF. Methods: We retrospectively reviewed 28 lung nodules in 16 subjects (age; $67.53{\pm}9.53$, M:F=14:2). Two patients had previous history of malignant cancer (small cell lung cancer and subglottic cancer). The diagnostic criteria on chest CT were size, morphology and serial changes of size. FDG PET was visually interpreted, and maximal SUV was calculated for quantitative analysis. Results: from 28 nodules, 18 nodules were interpreted as benign nodules, 10 nodules as malignant nodules by histopahthology or follow-up chest CT. The sensitivity and specificity of FDG PET were 100% and 94.4%, while those of CT were 70.0% and 44.4%, respectively. Malignant nodule was higher maxSUV than that of benign lung nodules ($7.68{\pm}3.96\;vs.\;1.22{\pm}0.65$, p<0.001). Inflammatory lesion in underlying IPF was significantly lower maxSUV than that of malignant nodules ($1.80{\pm}0.43$, p<0.001). The size of malignant and benign nodule were $23.95{\pm}10.15mm\;and\;10.83{\pm}5.23mm$ (p<0.01). Conclusion: FDG PET showed superior diagnostic performance to chest CT in differentiating lung nodules in patients with underlying IPF. FDG PET could be used to evaluate suspicious malignant lung nodule detected by chest in patients with IPF.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1983.05a
• /
• pp.8.2-9
• /
• 1983

Recently, the laryngomicrosurgery has been done for the removal of benign laryngeal mass and for the improvement of voice. For the evaluation of the effect of the treatment, there must be any objective method such as aerodynamic study, vocal fold vibration study, acoustic analysis, psycho-acoustic evaluation and the neuro-muscular study. The authors evaluated the phoniatric effect of the laryngomicrosurgery for the patients of 15 laryngeal polyps and 9 laryngeal nodules, who received pre-op. and post-op. vocal function study from Jun. 1981 to Mar. 1983. The results obtained were as follows ; 1) The post-op. mean value of the maximum phonation time was increased 40 % in the unilateral polyps, 62 % in the bilateral nodules and 18 % in the unilateral nodules. 2) The post-op. mean value of the phonation quotient was decreased 25 % in comparison with pre-op. value in the case of the bilateral polyps, 26 % in the unilateral polyps, 55 % in the bilateral nodules and 12 % in the unilateral nodules. 3) The post-op. mean value of the mean air flow rate was decreased 27 % in comparison with the pre-op. value in the case of the bilateral polyps, 25 % in the unilateral polyps, 65 % in the bilateral nodules, 25 % in the unilateral nodules. 4) The glottic chink of the 10 cases of polyps among the 11 cases were disappeared, and the glottic chink of the 5 cases of nodules among 7 cases were also disappeared after surgery. 5) The pre-op. hoarseness of the 10 cases of polyps among the pre-op. hoarseness of the 11 cases of polyps were changed to clear and the 3 cases of nodules were also changed to clear.

• Journal of Veterinary Clinics
• /
• v.17 no.1
• /
• pp.129-133
• /
• 2000

Based on pathological findings, 5 German shepherds, revealed a mean age of 7.6 years, showing no clinical signs were diagnosed as tracheopathia osteochondroplastica(TOC). Grossly, multiple small-sizecd nodules, appeared as cobble-stones, on the cartilage rings situated in the anterior trachea and the mucosal surface of the epiglottis were showed. Numerous tiny nodules were scattered on the pleural surface of the lung. The vascular walls of the heart were irregular and coarse apearance with calcification. Histopathologically, nodules in the trachea represented an irregular expansion of the underlying tracheal ring with protrusion into the submucosa and consisted of proliferated and calcified cartilage and bone with marrow spaces containing numbers of hematopoietic cells. Pulmonary calcinosis and calcification of the vascular walls of the heart were observed. Our observations suggested that TOC arises form eccondroses and exostoses of the tracheal cartilage rings.

• Journal of Veterinary Clinics
• /
• v.25 no.3
• /
• pp.200-201
• /
• 2008

A case of cutaneous fibroma was diagnosed in the skin of the right hindlimb of a Korean indigenous cattle in Kyungpook province, Korea. Grossly, the protruding skin nodules consisted of a solitary mass $(1.5{\times}1.5{\sim}3.0{\times}3.0cm)$ above large grapelike warty nodules $(11.0{\times}11.0cm)$ on the leg. These masses were firm and rubbery, and the cut surface was gray to white. Histopathologically, the benign neoplastic nodules consisted of spindle-type fibroblasts with collagen. Melanoma, sarcoma, and fibropapilloma were excluded because there was no sign of melanin, muscle type cells, or epidermal proliferation. To our knowledge, this is the first report of a cutaneous fibroma in a Korean indigenous cattle in Korea.

• Korean Journal of Microbiology
• /
• v.29 no.2
• /
• pp.143-147
• /
• 1991

The root nodules and Glycine max were classified as determinate nodule based on their morphological characteristics, and isolated endosymbiont as a Bradyrhizobium based on its growth rate and single subpolar flagellum. The isolate was similar to B. japonicum USDA110 in utilization of carbon source, growth at 38.deg.C and 2% NaCl, production of $H_{2}$S and especially in the restriction endonuclease digestion pattern of symbiotic genes, allowing them to be placed in sTI group together. The former, however, grew better than the later in broad pH range from 5.0 to 9.5. Infectivity and effectivity of the isolate were confirmed by inoculation of soybean seedlings with the isolates. Characteristics of the reisolated endosymbiont from induced root nodules were identical to those of the first isolate. From these results, it was confirmed that Bradyrhizobium strain isolated from the root nodules of Glycine max was a real symbiont, and was named B. japonicum SNU001.

• Journal of Chest Surgery
• /
• v.12 no.4
• /
• pp.307-311
• /
• 1979

Bronchogenic carcinoma with subcutaneous metastasis is rare, and the incidence ranged from 1.0 to 3.0 %. Therefore metastatic nodules are incidental findings in some instances. The distribution in order of frequency Is as follows: chest wall, scapular region, abdominal wall, course of spine, upper extremities and scalp etc, and mos. of nodules are between 0.5-2.0 cm in diameter. In this report, we present one case of a 54 year old male having bronchogenic carcinoma (squamous cell type) with multiple subcutaneous metastases. The metastatic nodules were located in subcutaneous tissue of right posterior chest wall ($4{\times}5$ cm), frontal scalp area (two; $2{\times}3$ cm, $0.5{\times}0.5$ cm), left scapular region ($1{\times}1$ cm) and left iliac crest ara ($1{\times}11$ cm).

• Ocean and Polar Research
• /
• v.36 no.4
• /
• pp.505-514
• /
• 2014

The development of deep seabed manganese nodules has been carried out with the aim of commercial development in 2023. It is important to forecast the price of the four metals (copper, nickel, cobalt, and manganese) extracted from manganese nodules because price change is a criterion for investment decision. The main purpose of the study is to forecast the price of four metals using the ARIMA model and VAR model, and calculate the MAPE to compare a goodness-of-fit between the two models. The estimated results of the two models reveal statistical significance and are in keeping with economic theory. The results of MAPE for goodness-of-fit show that the VAR model is between 0.1 and 0.2, and the ARIMA model is between 0.4 and 0.6. That is, the VAR model is better than the ARIMA model in forecasting changes in the price of metals.

• Korean Journal of Head & Neck Oncology
• /
• v.8 no.2
• /
• pp.97-105
• /
• 1992

One hundred and thirty-nine thyroid nodules were evaluated by aspiration biopsy cytology (ABC) and were compared with the postoperative histologic diagnosis during the period from May 1, 1986 through Aug. 31, 1992. The correlation betwen the two diagnoses proved to be comparable with a low incidence of false-negative diagnoses, but with a relatively high incidence of false-positive ones. The sensitivity was 93.5%, specificity 89.6%, false-negative rate 6.5%, false-positive rate 10.4%, positive predictability 87.9%, negative predictability 94.5%, and overall diagnostic accuracy 91.4%.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.20
• /
• pp.8613-8616
• /
• 2014

Background: The diagnostic approach to thyroid nodules involves ultrasound-guided fine needle aspiration biopsy (US-FNAB). We especially aimed to evaluate the contribution and the place of US-FNAB in preoperative evaluation of the malignant cases and draw attention to discordant cases diagnosed with papillary thyroid microcarcinoma (PTMC). Materials and Methods: A total of 276 cases were retrospectively reviewed who were subsequently diagnosed with a malignancy and who underwent US-FNAB. Results: Some 45 were found to have previously undergone the US-FNAB procedure. Of the patients in whom the surgical specimen was diagnosed with a malignancy, 21 (46.7%) were diagnosed as malignant or suspicious for malignancy, and 24 (53.3%) were concluded as benign or insufficient for diagnosis. Patients with the diagnosis of PTMC outnumbering the others was a striking finding (11 cases, 24%). Conclusions: We suggest performing repeat aspiration biopsy considering sampling errors in cases where inconsistency exists between clinical findings and cytological results in thyroid nodules smaller than 10 mm in diameter and with suspicious findings on ultrasonography.