• Korean Journal of Head & Neck Oncology
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• v.3 no.1
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• pp.15-24
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• 1987

This study is limited to epidermoid carcinoma arising in the larynx. The 623 patients in this series comprised 1.6% of all malignant neoplasms seen during the 20-year period .from 1965 to 1984 ; it comprised 13.2% of all cancers of the head and neck registered during this period. The male: female ratio was 11:1, and the highest incidence was in the fifth decade of life. Analysis by anatomical site revealed that 51.7% were supraglottic, 36.1% glottic, and 6.8% subglottic in oriain. One-hundred eighty-nine(79%) were clinically Stage III or Stage IV lesions at the time of the first visit. Of the total of 263 cases, 113 refused treatment, 4 definite radiation for $T_1$. lesion,21 underwent palliative therapy only, and 125 underwent surgical management with intent to cure. This surgical category included 53 patients who had surgical treatment only and 72 who underwent combined therapy(preoperative radiation, postoperative radiation, or inductive chemotherapy followed by surgery and postoperative radiation). The surgical management varied from partial laryngectomy to widefield laryngectomy and ipsilateral neck dissection. In 14.4% pathologically positive node or nodes were found in the clinically negative contralateral neck nedes. Such contralateral spread was most common in supraglottic site of origin(222%). Combined modality of management was compared to single therapy. Although results at three years showed no difference in determinate disease-free survival between patients treated by surgery only and those treated by surgery followed by postoperative radiation therapy at 5 years a statistically significant difference emerged, only 36% of those receiving surgery alone surviving as compared to 65.4% in the surgery with radiation group.

• Radiation Oncology Journal
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• v.31 no.1
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• pp.25-33
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• 2013

Purpose: We reviewed the treatment outcomes and prognostic factors for patients with anal canal carcinoma who were treated with curative intent chemoradiotherapy (CRT) at Severance Hospital from 2005 to 2011. Materials and Methods: Data for 38 eligible patients treated during this period were reviewed. All patients were treated with curative intent using radiotherapy (RT) with (n = 35) or without concomitant chemotherapy (n = 3). Among 35 patients who received CRT, most of the chemotherapeutic regimens were either 5-fluorouracil (5-FU) plus mitomycin C (23 patients) or 5-FU plus cisplatin (10 patients). Recurrence-free survival (RFS), colostomy-free survival (CFS), overall survival (OS), and locoregional control (LRC) rates were calculated using the Kaplan-Meier method and survival between subgroups were compared using the log-rank test. Cox's proportional hazard model was used for multivariate analysis. Results: Over a median follow-up period of 44 months (range, 11 to 96 months), 3-year RFS, CFS, OS, and LRC were 80%, 79%, 85%, and 92%, respectively. In multivariate analysis, tumor size >4 cm was an independent predicting factor for poorer RFS (hazard ratio [HR], 6.35; 95% confidence interval [CI], 1.42 to 28.5; p = 0.006) and CFS (HR, 6.25; 95% CI, 1.39-28.0; p = 0.017), while the presence of external iliac lymph node metastasis was an independent prognosticator for poorer OS (HR, 9.32; 95% CI, 1.24 to 70.3; p = 0.030). No treatment-related colostomies or deaths occurred during or after treatment. Conclusion: Curative intent CRT resulted in excellent outcomes that were comparable to outcomes in previous randomized trials. No severe treatment-related toxicities were observed.

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.655-661
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• 2007

Malignant melanoma is rare in Asians and one of the poorer prognostic diseases. Malignant melanoma accounts for only a small ratio of all skin cancers, but it causes the greatest number of skin cancer - related deaths worldwide. Melanoma incidence has continued to increase worldwide and in Korea, like other countries, the number of patients has increased compared with previous cancer incidence data. In this case report, we describe a case of a malignant melanoma patient who showed neck node metastasis (right supraclavicular area) after wide excision of facial melanoma 2 years before the diagnosis of relapse. The patient refused to get conventional western medical treatment including chemotherapy and the size of cancer increased over the 5 months of clinical follow-up. After 4 months of traditional Korean medical treatment using allergen-removed Rhus verniciflua Stokes(A-RVS), however, the size of cancer mass decreased and the patient showed no side effects. Further study will be needed in order to determine the long-term effect of allergen-removed Rhus verniciflua Stokes on patients with malignant melanoma.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.463-463
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• 2012

ITRS (international technology roadmap for semiconductors)에 따르면 MOS(metal-oxide-semiconductor)의 CD (critical dimension)가 45 nm node이하로 줄어들면서 poly-Si/$SiO_2$를 대체할 수 있는 poly-Si/metal gate/high-k dielectric이 대두된다고 보고하고 있다. 일반적으로 high-k dielectric를 식각시 anisotropic 한 식각 형상을 형성시키기 위해서 plasma를 이용한 RIE (reactive ion etching)를 사용하고 있지만 PIDs (plasma induced damages)의 하나인 PIED (plasma induced edge damage)의 발생이 문제가 되고 있다. PIED의 원인으로 plasma의 direct interaction을 발생시켜 gate oxide의 edge에 trap을 형성시키므로 그 결과 소자 특성 저하가 보고되고 있다. 그러므로 본 연구에서는 이에 차세대 MOS의 high-k dielectric의 식각공정에 HDP (high density plasma)의 ICP (inductively coupled plasma) source를 이용한 원자층 식각 장비를 사용하여 PIED를 줄일 수 있는 새로운 식각 공정에 대한 연구를 하였다. One-monolayer 식각을 위한 1 cycle의 원자층 식각은 총 4 steps으로 구성 되어 있다. 첫 번째 step은 Langmuir isotherm에 의하여 표면에 highly reactant atoms이나 molecules을 chemically adsorption을 시킨다. 두 번째 step은 purge 시킨다. 세 번째 step은 ion source를 이용하여 발생시킨 Ar low energetic beam으로 표면에 chemically adsorbed compounds를 desorption 시킨다. 네 번째 step은 purge 시킨다. 결과적으로 self limited 한 식각이 이루어짐을 볼 수 있었다. 실제 공정을 MOS의 high-k dielectric에 적용시켜 metal gate/high-k dielectric CMOSFETs의 NCSU (North Carolina State University) CVC model로 구한 EOT (equivalent oxide thickness)는 변화가 없으면서 mos parameter인 Ion/Ioff ratio의 증가를 볼 수 있었다. 그 원인으로 XPS (X-ray photoelectron spectroscopy)로 gate oxide의 atomic percentage의 분석 결과 식각 중 발생하는 gate oxide의 edge에 trap의 감소로 기인함을 확인할 수 있었다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.8
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• pp.5559-5564
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• 2015

A variety of routing protocols targeted specifically at mobile ad-hoc network environments have been developed. Mobile ad-hoc network is a self-organizing temporary network, operating without the aid of any established wired infrastructure. The proposed protocol supports seamless communication services between the mobile hosts within a mobile ad-hoc network environments. In particular, our protocol makes faster route re-establishment possible by maintaining multiple paths in each mobile host, and also, the protocol provides reliable communication environments. We compare the performance of RWP model with that of LW model. This paper shows delivery ratio with single path and non-disjoint multiple path according to mobility model and node numbers.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.8
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• pp.4072-4089
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• 2018

This paper introduces a scheme for optimizing the material properties of mass-spring systems of different resolutions to provide coherent behavior for reduced level-of-detail in MSS(Mass-Spring System) meshes. The global optimal material coefficients are derived to match the behavior of provided reference mesh. The proposed method also gives us insight into levels of reduction that we can achieve in the systematic behavioral coherency among the different resolution of MSS meshes. We obtain visually acceptable coherent behaviors for cloth models based on our proposed error metric and identify that this method can significantly reduce the resolution levels of simulated objects. In addition, we have confirmed coherent behaviors with different resolutions through various experimental validation tests. We analyzed spring force estimations through triangular Barycentric coordinates based from the reference MSS that uses a Gaussian kernel based distribution. Experimental results show that the displacement difference ratio of the node positions is less than 10% even if the number of nodes of $MSS^{sim}$ decreases by more than 50% compared with $MSS^{ref}$. Therefore, we believe that it can be applied to various fields that are requiring the real-time simulation technology such as VR, AR, surgical simulation, mobile game, and numerous other application domains.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.4A
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• pp.377-385
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• 2010

In this paper, we propose a SInk-initiated geographic Multicast (SIM) protocol to reduce frequent location updates from mobile sinks to a source and to achieve fast multicast tree construction and data delivery. The proposed protocol allows sinks to construct their own data delivery paths to a source node and a multicast tree to be atomically constructed by merging the paths. Then, the source forwards data to the destinations down the multicast tree. This paper also propose a round-based virtual infrastructure with a radial shape for increasing the merging probability of data delivery paths and reducing reconstruction ratio of the multicast tree due to mobility of sinks. Simulation results show that the proposed protocol is superior to previous SOurce-initiated geographic Multicast (SOM) protocols in term of average data delivery delay and average energy consumption.

• 유체기계공업학회:학술대회논문집
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• 2004.12a
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• pp.396-401
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• 2004

In this paper, a 1MW HAWT(FIL-1000) rotor blade has been designed by BEMT(Blade Element Momentum Theory) with Prandtl's tip loss. Also, a 3-D flow and performance analysis on the FIL-1000 rotor blade has been carried out by using the 3-D Navier-Stokes commercial solver (CFX-5.7) to provide more efficient design techniques to the large-scale HAWT engineers. The rated power and itsapproaching wind velocity at design point (TSR=7.5) are 1MW and 9.99m/s respectively. The rotor diameter is 54.5m and the rotating speed is 26.28rpm. Airfoils such as FFA W-301, DU91-W-250, DU93-W-210, NACA 63418, NACA 63415 consist of the rotor blade from hub to tip. Recent CFX version, 5.7 was adopted to simulate 3-D flow field and to analyze the performance characteristics of the rotor blade. Entire mesh node number is about 730,000 and it is generated by ICEM-CFD to achieve better mesh quality The predicted maximum power occurringat the design tip speed ratio is 931.45kW. Approaching to the root, the inflow angle becomes large, which causesthe blade to be stalled in the region. Therefore, k-$\omega$ SST turbulence model was used to predict the quantitative flow information more accurately. Application of commercial CFD code to optimum blade design and performance analysis was proved to be more effective environment to HAWT blade designers.

• Journal of Communications and Networks
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• v.15 no.3
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• pp.312-320
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• 2013

Home evolved Node-B (HeNB), also called a femtocell or a femto base station, is introduced to provide high data rate to indoor users. However, two main problems arise in femtocell networks: (1) Small coverage area of HeNB, which results in limited cell-splitting gain and ping-pong handover (HO) problems and (2) high inter-femtocell interference because HeNBs may be densely deployed in a small region. In this study, an efficient cooperation mechanism called an HeNB-aided virtual-HO (HaVHO) scheme is proposed to expand the coverage area of femtocells and to reduce inter-femtocell interference. The cooperation among neighbor HeNBs is exploited in HaVHO by enabling an HeNB to relay the data of its neighbor HeNB without an HO. The HaVHO procedure is compatible with the existing long term evolution specification, and the information exchange overhead in HaVHO is relatively low. To estimate the signal to interference plus noise ratio improvement, the area average channel state metric is proposed, and the amount of user throughput enhancement by HaVHO is derived. System-level simulation shows that HaVHO has a better performance than the other four schemes, such as lesser radio link failure, lesser ping-pong handover, lesser short-stay handover, and higher user throughput.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.90-92
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• 2017

Due to the popularity of social networks and the development of technology in mobile networking, the mobile social networks (MSNs) provide opportunities for the spread of information between mobile devices. As a result, understanding the information diffusion in the emerging MSNs is a critical issue. Many research studies have addressed diffusion minimization, which is a problem of how to find the proper initial k users who can effectively propagate as widely as possible in the minimum amount of time, similar to influence maximization. We address a study on association analysis among nodes in information diffusion and mobility pattern for mobile social networks. Experiments in our study were conducted in the Opportunistic Network Environment (ONE) simulator using GPS trace of mobile node, to show that the study results in MSNs. We also demonstrate that our experiments outperform other existing algorithms with various communication range and ratio of k influential nodes.