• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1725-1730
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• 2014

Management of patients with stage II colorectal carcinomas remains challenging as 20 - 30% of them will develop recurrence. It is postulated that these patients may harbour nodal micrometastases which are imperceptible by routine histopathological evaluation. The aims of our study were to evaluate (1) the feasibility of multilevel sectioning method utilizing haematoxylin and eosin stain and immunohistochemistry technique with cytokeratin AE1/AE3, in detecting micrometastases in histologically-negative lymph nodes, and (2) correlation between nodal micrometastases with clinicopathological parameters. Sixty two stage I and II cases with a total of 635 lymph nodes were reviewed. Five-level haematoxylin and eosin staining and one-level cytokeratin AE1/AE3 immunostaining were performed on all lymph nodes retrieved. The findings were correlated with clinicopathological parameters. Two (3.2%) lymph nodes in two patients (one in each) were found to harbour micrometastases detected by both methods. With cytokeratin AE1/AE3, we successfully identified four (6.5%) patients with isolated tumour cells, but none through the multilevel sectioning method. Nodal micrometastases detected by both multilevel sectioning and immunohistochemistry methods were not associated with larger tumour size, higher depth of invasion, poorer tumour grade, disease recurrence or distant metastasis. We conclude that there is no difference between the two methods in detecting nodal micrometastases. Therefore it is opined that multilevel sectioning is a feasible and yet inexpensive method that may be incorporated into routine practice to detect nodal micrometastases in centres with limited resources.

• Transactions of Materials Processing
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• v.13 no.7
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• pp.594-599
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• 2004

In the sheet metal forming operations, the strain measurement of sheet panel is an essential work which provides the formability information needed in die design, process design, and product inspection. To measure efficiently complex geometry strains, the 3-dimensional automative strain measurement system, which theoretically has a high accuracy but practically has about 3～5％ strain error, is often used. For eliminating the strain error resulted in measuring the strains of formed panels using an automated strain measurement system, the position error calibration method is suggested, which computes accurate strains using the grids with accurate nodal coordinates. The accurate nodal coordinates are calculated by adding the nodal coordinates measured by the measurement system and the position error found using the multiple regression method as a function of the main error parameters obtained from the analysis of strain error in a standard cube. For the verification, the strain distributions of square and dome cups obtained from the position error calibration method are compared with those provided by the finite element analysis and ASAME.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1994.10a
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• pp.210-216
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• 1994

The velocity fields can be composed by nodal points using shape function. Forging load and deformed profile are obtained by minimizing total energy consumption rate which is function of unknown velocities at each nodal points. The velocity and stremiline distribution can also be investigated at the deformation profile. The effectiveness of proposed method in this paper is demonstrated by comparing with those of FEM and experiment, that is the results of upset forging problem. Obtained results are compared with FEM and experiment and fairly good agreement is found between them.

• Nuclear Engineering and Technology
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• v.53 no.5
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• pp.1391-1402
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• 2021

The aim of this work is to prepare a neutron noise calculator based on the second order of average current nodal expansion method (ACNEM). Generally, nodal methods have the ability to fulfill the neutronic analysis with adequate precision using coarse meshes as large as a fuel assembly size. But, for the zeroth order of ACNEM, the accuracy of neutronic simulations may not be sufficient when coarse meshes are employed in the reactor core modeling. In this work, the capability of second order ACNEM is extended for solving the neutron diffusion equation in the frequency domain using coarse meshes. For this purpose, two problems are modeled and checked including a slab reactor and 2D BIBLIS PWR. For validating of results, a semi-analytical solution is utilized for 1D test case, and for 2D problem, the results of both forward and adjoint neutron noise calculations are exploited. Numerical results indicate that by increasing the order of method, the errors of frequency dependent coarse mesh solutions are considerably decreased in comparison to the reference. Accordingly, the accuracy of second order ACNEM can be acceptable for the neutron noise calculations by using coarse meshes in the nuclear reactor core.

• Nuclear Engineering and Technology
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• v.52 no.11
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• pp.2422-2430
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• 2020

In order to improve calculational efficiency of the CAPP code in the analysis of the hexagonal reactor core, we have tried to implement a refined AFEN method with transverse gradient basis functions and interface flux moments in the hexagonal geometry. The numerical scheme for the refined AFEN method adopted here is the response matrix method that uses the interface partial currents as nodal unknowns instead of the interface fluxes used in the original AFEN method. Since the response matrix method is single-node based, it has good properties such as good calculational efficiency and parallel computing affinity. Because a refined AFEN method equivalent nonlinear FDM response matrix method tried first could not provide a numerically stable solution, a direct formulation of the refined AFEN response matrix were developed. To show the numerical performance of this response matrix method against the original AFEN method, the numerical error analyses were performed for several benchmark problems including the VVER-440 LWR benchmark problem and the MHTGR-350 HTGR benchmark problem. The results showed a more than three times speedup in computing time for the LWR and HTGR benchmark problems due to good convergence and excellent calculational efficiency of the refined AFEN response matrix method.

• Structural Engineering and Mechanics
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• v.36 no.1
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• pp.95-110
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• 2010

Two-dimensional elastic contact problems, including normal, tangential, and rolling contacts, are treated with the finite element method in this study. Stress boundary conditions and kinematic conditions are transformed into multiple point constraints for nodal displacements in the finite element method. Upon imposing these constraints into the finite element system equations, the calculated nodal stresses and nodal displacements satisfy stress and displacement contact conditions exactly. Frictional and frictionless contacts between elastically identical as well as elastically dissimilar materials are treated in this study. The contact lengths, sizes of slip and stick regions, the normal and the shear stresses can be found.

• Journal of Mechanical Science and Technology
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• v.17 no.7
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• pp.986-998
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• 2003

In this paper, an adaptive numerical integration scheme, which does not need non-overlapping and contiguous integration meshes, is proposed for the MLPG (Meshless Local Petrov-Galerkin) method. In the proposed algorithm, the integration points are located between the neighboring nodes to properly consider the irregular nodal distribution, and the nodal points are also included as integration points. For numerical integration without well-defined meshes, the Shepard shape function is adopted to approximate the integrand in the local symmetric weak form, by the values of the integrand at the integration points. This procedure makes it possible to integrate the local symmetric weak form without any integration meshes (non-overlapping and contiguous integration domains). The convergence tests are performed, to investigate the present scheme and several numerical examples are analyzed by using the proposed scheme.

• Computers and Concrete
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• v.4 no.4
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• pp.259-272
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• 2007

A method based on the lower-bound theorem of limit analysis is presented for the capacity assessment of nodal zones in strut-and-tie models. The idealized geometry of the nodal zones is formed by the intersection of effective widths of the framing struts and ties. The stress distribution is estimated by dividing the nodal zones into constant stress triangles separated by lines of stress discontinuity. The strength adequacy is verified by comparing the biaxial stress field in each triangle with the corresponding failure criteria. The approach has been implemented in a computer-based strut-and-tie tool called CAST (Computer-Aided Strut-and-Tie). An application example is also presented to illustrate the approach.

• Composites Research
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• v.32 no.5
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• pp.243-248
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• 2019

As demand of light weight in the automotive industry has increased, the cowl cross member has been investigated using various methods to change the material. Conventionally, a cowl cross member has been made of steel and aluminum, but recently researchers tested multi-material such as aluminum and plastic. We studied a new model of the cowl cross member made of composite and non ferrous materials. For products with a high degree of freedom in design, generally, the method of topology optimization is advantageous and for the partial bracket part of the cowl cross member had a degree of freedom in the design, a topology optimization is appropriate. Considering the characteristics of the cowl cross members, we need research to minimize the weight while having the performance of noise, vibration and harshness(NVH). Taking the mounting status of the product into consideration, we used an assembly model to optimize the cowl cross member. But this method took too much time so we considered simple cowl cross member assemble conditions using the direct matrix input method(DMI) with the Craig-Bampton Nodal Method. This method is capable of considering the status of the assembly without assembling the model, which reduced the solving time and increased the accuracy comparison with a cowl cross member without DMI.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.3
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• pp.82-87
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• 2007

This paper measures power quality of bus in case electric charges about customer are imposed by each bus, supposed that can calculate this cost. When reflected this in system planning, expected cost proposed following method through sample system. To calculate nodal cost operating condition of power equipment calculates nodal cost[$/MVAH] supposing by situation that is optimized by OPF(optimal power flow) in system. The damage cost that is shed by fault that happen during year of loads in system that is linked on each bus was produced. As a result, proposed method was very effective in case of calculating bus total cost including power quality cost.