• 방송공학회논문지
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• 제14권3호
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• pp.322-331
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• 2009

본 논문은 윤곽선 기반 메쉬 최적화를 이용한 스테레오 영상의 효율적인 데이터 표현 방법을 제안한다. 스테레오 영상에 대한 메쉬 기반 2차원 워핑은 주로 제어점 선택과 선택된 제어점들의 시차 정보 추정 성능에 의존한다. 따라서 제안된 방법은 제어점 선택을 위하여 강한 윤곽선과 객체의 경계선만으로 구성된 특징 지도를 생성하고 이를 기반으로 격자형 메쉬를 생성한다. 또한, 지역단위로 2차원 워핑을 수행하며 목적영상과의 오차를 최소로 하는 제어점의 위치를 반복적으로 추정하게 된다. 최적화된 제어점 위치를 찾기 위한 반복적 2차원 워핑 과정은 많은 계산 시간을 요구하기 때문에 이를 개선하기 위하여 입력된 스테레오 영상은 수평 시차만 존재하고 최적의 제어점 위치는 객체의 경계선을 포함한 윤곽선 위에 존재함을 가정한다. 따라서 제안한 윤곽선 기반 워핑 방법은 수평선 위에 윤곽선만을 따라 반복적으로 최적화된 제어점 위치를 탐색한다. 본 논문의 실험에서는 스테레오 영상에 대하여 제어점 수에 따른 신호에 대한 잡음비(PSNR)를 측정하여 기존 방법과 제안한 방법의 품질을 비교 하였다. 뿐만 아니라 최적의 메쉬 생성을 위한 수행시간을 비교하여 평가하였다. 실험 결과를 통하여 제안한 방법은 적은 수의 제어점을 이용하여 품질의 저하를 줄이고 빠르게 최적의 메쉬를 생성함으로써 효율적인 스테레오 영상 표현 방법을 제공하였다.

• 한국수자원학회논문집
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• 제43권9호
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• pp.769-780
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• 2010

'위상적 평가'와 '수리학적 평가'를 통해 수요절점에서 필요한 수량을 필요한 압력으로 충분히 공급할 수 있는지의 여부를 정량화하고 이를 신뢰성의 산정을 위한 기준으로 사용하는 것은 대표적인 상수관망시스템의 신뢰성산정 방법이다. 하지만 '수리학적 평가'를 이용한 수요절점에서의 압력확보 여부를 신뢰성 산정에 사용한 기존의 연구들은 'Demand-Driven Analysis의 사용'과 '사용성의 미고려'라는 두 가지 측면에 있어서 문제가 있다. 또한 비정상상태인 상수관망시스템의 수리모의 적합한 Pressure-Driven Analysis를 이용한 연구들도 신뢰성 산정에 있어 가능공급량만을 고려하고 사용성을 고려하지 않아, Pressure-Driven Analysis의 장점이 효율적으로 사용되지 않은 단점이 있다. 본 연구에서는 기 개발 된 Pressure-Driven Analysis 모형인 HSPDA모형과, 거리척도 방법을 이용하여 수량과 수압을 동시에 고려하는 신뢰성 분석기법을 제안하였다. 제안된 기법을 상수관망에 적용하여 기존의 연구결과와 비교하였고 이를 바탕으로 수립 가능한 신뢰성 확보방안을 제시하였다.

• Journal of Gastric Cancer
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• 제4권1호
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• pp.32-35
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• 2004

Purpose: The most important prognostic factors in gastric cancer is the depth of invasion of the primary tumor and lymph node metastasis. The nodal staging of the 5th edition of the Union Internationale Contrala Cancrums (UICC) TNM classification in 1997 was changed based on the number of metastatic lymph node. We attempted to evaluate the prognostic significance of N2 group metastasis in pT3pN1 gastric cancer patients by comparing two different nodal staging systems. Materials and Methods: A retrospective analysis was made for 352 gastric cancer patients who underwent curative resection, including D2 dissection, from 1991 to 1997 at Asan Medical Center. A clinicopathologic comparison between two groups by using a nodal staging systems was summarized into a table. Cumulative survival rates were calculated by using the Kaplan-Meier method. The difference between the two groups was evaluated by using the log rank test with SPSS 11.5 for Windows Results: There were no statistical differences in clinicopathologic factors. However, there was a significant difference in survival rate between the two groups (P=0.0009). This suggests that N2 group metastasis in pT3pN1 gastric cancer patients has a clinical significance for predicting prognosis. Conclusion: Our results suggest a possibility of prognostic significance of N2 group metastasis. Therefore, anatomical location of the lymph node should be described.

• Radiation Oncology Journal
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• 제11권1호
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• pp.159-166
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• 1993

A retrospective analysis was done for 69 patients with Stage I and II non-Hodgkin's lymphoma who were treated from May 1981 to December 1990, in the Department of Radiadtion Oncology, Korea University Hospital. We used Ann Arbor Staging system and Working Formulation for histological classification. Forty-three patients (43/69, $62.3{\%}$) were Stage I and 26 patients (26/69, $37.7{\%}$) were Stage II, and B symptom was found in $10.1{\%}$ (7/69). Nodal lymphoma was $21.7{\%}$ (15/69); 14 patients with supradiaphragmatic disease and 1 patient with infradiaphragmatic disease. Extranodal lymphoma was $78.3{\%}$ (54/69): $64.8{\%}$ (35/54) for head and neck, $25.9{\%}$ (14/54) for gastrointestinal tract. Histologically, low grade consists of $8.7{\%}$ (6/69), intermediate grade $84.2{\%}$ (56/69), high grade $10.1{\%}$ (7/69), and diffuse large cell type was the most frequent form with 36 patients (36/69, $52.2{\%}$). Eighteen patients ($26.1{\%}$) were treated with radiation therapy alone,20 patients ($29.0{\%}$) with radiation therapy combined with chemotherapy, 15 patients ($21.7{\%}$) with radiation therapy combined with surgery and chemotherapy, Median survival duration was 28 months, and the range of survival time was from 1 month to 134 months. Overall five-year survival rate for Stage I and II disease was $54.2{\%}$, with $64.5{\%}$ for Stage I and $37.1{\%}$ for Stage II. For nodal lymphoma,5-year survival rate was $45.9{\%}$, and $56.5{\%}$ for extranodal lymphoma; $60.6{\%}$ for head and neck, $52.9{\%}$ for GI tract primary disease. Local control rate for all patients was $88.4{\%}$ (61/69), with $80{\%}$ (12/15) for nodal lymphoma and $90.7{\%}$ (49/54) for extranodal lymphoma. The total failure rate was $34.8{\%}$ (24/69). Five of 24 ($20.8{\%}$) patients who were failed developed local failure only, $12.5{\%}$ (3/24) local failure with distant failure, and distant failure only were found in $66.7{\%}$ (16/24). Between nodal lymphoma and extranodal lymphoma, there was no significant survival difference, but extranodal lymphoma showed higher incidence.

• Journal of Gastric Cancer
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• 제4권2호
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• pp.109-120
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• 2004

Purpose: Individual gastric cancers demonstrate complicated genetic alterations. The PCR-based analysis of polymorphic microsatellite sequences on cancer-related chromosomes has been used to detect chromosomal loss and microsatellite instability. For the purpose of preoperative usage, we analyzed the correspondance rate of the microsatellite genotype between endoscopic biopsy and surgical specimens. Materials and Methods: Seventy-three pairs of biopsy and surgical specimens were examined for loss of heterozygosity and microsatellite instability by using 40 microsatellite markers on eight chromosomes. Microsatellite alterations in tumor DNAs were classified into a high-risk group (baselinelevel loss of heterozygosity: 1 chromosomal loss in diffuse type and high-level loss of heterozygosity: 4 or more chromosomal losses) and a low-risk group (microsatellite instability and low-level loss of heterozygosity: 2 or 3 chromosomal losses in diffuse type or $1\∼3$ chromosomal losses in intestinal type) based on the extent of chromosomal loss and microsatellite instability. Results: The chromosomal losses of the biopsy and the surgical specimens were found to be different in 21 of the 73 cases, 19 cases of which were categorized into a genotype group of similar extent. In 100 surgical specimens, the high-risk genotype group showed a high incidence of nodal involvement (19 of 23 cases: $\leq$5 cm; 23 of 24 cases: >5 cm) irrespective of tumor size while the incidence of nodal involvement for the low-risk genotype group depended on tumor size (5 of 26 cases: $\leq$5 cm; 18 of 27 cases: >5 cm). Extraserosal invasion was more frequent in large-sized tumor in both the high-risk genotype group ($\leq$5 cm: 12 of 23 cases; >5 cm: 23 of 24 cases) and the low-risk genotype group ($\leq$5 cm: 7 of 26 cases; >5 cm: 16 of 27 cases). The preoperative prediction of tumor invasion and nodal involvement based on tumor size and genotype corresponded closely to the pathologic tumor stage (ROC area >0.7). Conclusion: An endoscopic biopsy specimen of gastric cancer can be used to make a preoperative genetic diagnosis that accurately reflect the genotype of the corresponding surgical specimen.

• Korean Journal of Radiology
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• 제24권6호
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• pp.498-511
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• 2023

Objective: To evaluate the diagnostic performance of chest computed tomography (CT)-based qualitative and radiomics models for predicting residual axillary nodal metastasis after neoadjuvant chemotherapy (NAC) for patients with clinically node-positive breast cancer. Materials and Methods: This retrospective study included 226 women (mean age, 51.4 years) with clinically node-positive breast cancer treated with NAC followed by surgery between January 2015 and July 2021. Patients were randomly divided into the training and test sets (4:1 ratio). The following predictive models were built: a qualitative CT feature model using logistic regression based on qualitative imaging features of axillary nodes from the pooled data obtained using the visual interpretations of three radiologists; three radiomics models using radiomics features from three (intranodal, perinodal, and combined) different regions of interest (ROIs) delineated on pre-NAC CT and post-NAC CT using a gradient-boosting classifier; and fusion models integrating clinicopathologic factors with the qualitative CT feature model (referred to as clinical-qualitative CT feature models) or with the combined ROI radiomics model (referred to as clinical-radiomics models). The area under the curve (AUC) was used to assess and compare the model performance. Results: Clinical N stage, biological subtype, and primary tumor response indicated by imaging were associated with residual nodal metastasis during the multivariable analysis (all P < 0.05). The AUCs of the qualitative CT feature model and radiomics models (intranodal, perinodal, and combined ROI models) according to post-NAC CT were 0.642, 0.812, 0.762, and 0.832, respectively. The AUCs of the clinical-qualitative CT feature model and clinical-radiomics model according to post-NAC CT were 0.740 and 0.866, respectively. Conclusion: CT-based predictive models showed good diagnostic performance for predicting residual nodal metastasis after NAC. Quantitative radiomics analysis may provide a higher level of performance than qualitative CT features models. Larger multicenter studies should be conducted to confirm their performance.

• 한국작물학회:학술대회논문집
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• 한국작물학회 1993년도 추계 학술대회지
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• pp.54-55
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• 1993

• 한국작물학회:학술대회논문집
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• 한국작물학회 1993년도 추계 학술대회지
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• pp.52-53
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• 1993

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 추계학술대회 논문요약집
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• pp.239-239
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• 2003

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2010년도 춘계학술대회 논문집
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• pp.157-158
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• 2010