• 제목/요약/키워드: Nodal

검색결과 1,246건 처리시간 0.029초

Predictive Factors for Supraclavicular Lymph Node Recurrence in N1 Breast Cancer Patients

  • Kong, Moonkyoo;Hong, Seong Eon
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권4호
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    • pp.2509-2514
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    • 2013
  • Background: The purpose of this study was to identify predictive factors for supraclavicular lymph node recurrence (SCLR) in N1 breast cancer patients and define a high-risk subgroup who might benefit from supraclavicular nodal radiotherapy (RT). Materials and Methods: From January 1995 to December 2009, 113 breast cancer patients with 1 to 3 positive axillary lymph nodes were enrolled in this study. All patients underwent breast-conserving surgery (BCS) or modified radical mastectomy (MRM). RT was given to all patients who received BCS. Among the patients given MRM, those with breast tumors >5 cm in size received RT. Regional nodal irradiation was not applied. Systemic chemotherapy was given to 105 patients (92.9%). Patient data were retrospectively reviewed and analyzed to identify predictive factors for SCLR. Results: The median follow-up duration was 6.5 years, with 5- and 10-year actuarial SCLR rates of 9.3% and 11.2%, respectively. Factors associated with SCLR on univariate analysis included histologic grade, number of dissected axillary lymph nodes, lymphovascular invasion, extracapsular extension (ECE), and adjuvant chemotherapy. On multivariate analysis, histologic grade and ECE remained significant. The patient group with grade 3 and ECE had a significantly higher rate of SCLR compared with the remainder (5-year SCLR rate; 71.4% vs. 4.0%, p<0.001). Conclusions: Histologic grade and ECE status are significant predictive factors for SCLR. Supraclavicular nodal RT is necessary in N1 breast cancer patients featuring histologic grade 3 and ECE.

절대절점좌표를 이용한 고속철도 집전성능 동역학 해석 모델 개발 및 검증 (Development and Verification of a Dynamic Analysis Model for the Current-Collection Performance of High-Speed Trains Using the Absolute Nodal Coordinate Formulation)

  • 이진희;박태원
    • 대한기계학회논문집A
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    • 제36권3호
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    • pp.339-346
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    • 2012
  • 철도차량의 집전성능 및 이선율에 대한 사전 평가는 철도차량의 고속화와 더불어 중요시되는 문제이다. 본 논문에서는 유연체 다물체 동역학 해석 기법을 이용하여 가선과 판토그래프 사이의 동적상호작용에 대한 시뮬레이션 모델을 개발하였다. 해석 모델에서 판토그래프는 강체로 모델링 하였으며, 가선계는 탄성 대변형체의 거동을 효과적으로 표현할 수 있는 절대절점좌표를 이용하여 구현하였다. 또한, 가선계와 판토그래프 간의 동적 상호작용의 표현을 위하여 서로간의 상대운동은 슬라이딩 조인트를 이용하여 구속하였다. 개발된 해석 프로그램을 이용하여 철도차량의 주행 속도에 따라 발생하는 접촉력 및 이선율을 평가하였다. 개발 프로그램의 해석 모델 및 시뮬레이션에 대한 신뢰성은 가선계와 판토그래프의 동적 상호작용 시뮬레이션 방법에 대한 국제 규정인 EN 50318에 의하여 검증하였다. 해석 모델의 개발을 통하여 개발 중인 고속철도의 집전성능을 평가할 수 있는 기반을 마련하였다.

In vitro Plant Regeneration from Apical Bud and Nodal Segments of Anthocepahalus Cadamba - An important sacred and medicinal tree

  • Kavitha, M.;Kalaimagal, I.;Mercy, S.;Sangeetha, N.;Ganesh, D.
    • Journal of Forest and Environmental Science
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    • 제25권2호
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    • pp.111-118
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    • 2009
  • Multiple shoot induction and plant regeneration using apical bud and nodal explants of 100 year old tree of Anthocephalus cadamba, an important sacred and medicinal tree in India was achieved for the first time. Aseptic explants cultured in Murashige and Skoog (MS) medium augmented with different concentrations of BAP (0.1, 0.5, 1.0, 2.5, 5.0 and 10 mg/l), when maintained for 60 days, healthy shoots were induced in presence of BAP (1 mg/l). Lower concentrations of BAP (0.1 - 0.5 mg/l) induced only one shoot per explant. Increase in number of shoots per explant was observed in presence of higher concentrations of BAP (2.5, 5.0 and 10 mg/l). However, elongation of shoots was completely inhibited. Bud break and shoot regeneration was largely associated with seasonal factors. Apical buds cultured during June to August exhibited early bud break within two weeks of initial culture. In rest of the months, bud break and shoot regeneration was very slow irrespective of the various concentrations of BAP used in the medium. Explants sourced from three different maturity levels of shoots indicated that actively growing shoots from the mother plant with 1 - 2 nodal segments was more suitable for culture initiation than the explants collected from mature shoots at dormant stage. Regenerated shoots with 2 - 3 pairs of leaves when transferred to half strength MS medium fortified with IBA (1 mg/l), 60% of the shoots induced healthy roots, indicating the possibility of large scale micropropagation.

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3차원 솔리드 요소를 이용한 용접부 핫스팟 응력 계산에 대한 연구 (Study on Hot Spot Stress Calculation for Welded Joints using 3D Solid Finite Elements)

  • 오정식;김유일;전석희
    • 한국해양공학회지
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    • 제29권1호
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    • pp.45-55
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    • 2015
  • Because of the high stress concentration near the toe of a welded joint, the calculation of local stress using the finite element method which is relevant to the fatigue strength of the weld toe crack, is a challenging task. This is mainly caused by the sensitivity of finite element analysis, which usually occurs near the area of a dramatically changing stress field. This paper presents a novel numerical method through which a less mesh-sensitive local stress calculation can be achieved based on the 3D solid finite element, strictly sticking to the original definition of hot spot stress. In order to achieve the goal, a traction stress, defined at 0.5t and 1.5t away from the weld toe, was calculated using either a force-equivalent or work-equivalent approach, both of which are based on the internal nodal forces on the imaginary cut planes. In the force-equivalent approach, the traction stress on the imaginary cut plane was calculated using the simple force and moment equilibrium, whereas the equivalence of the work done by both the nodal forces and linearized traction stress was employed in the work-equivalent approach. In order to confirm the validity of the proposed method, five typical welded joints widely used in ships and offshore structures were analyzed using five different solid element types and four different mesh sizes. Finally, the performance of the proposed method was compared with that of the traditionally used surface stress extrapolation method. It turned out that the sensitivity of the hot spot stress for the analyzed typical welded joints obtained from the proposed method outperformed the traditional extrapolation method by far.

석탄층 메탄가스 생산 특성을 고려한 포집시스템 최적 운영조건 노달분석 (Nodal Analysis of Optimum Operating Condition on Gathering System Considering Coalbed Methane Production Characteristics)

  • 정우동;조원준;이제설;유혜진;서문혁
    • 한국가스학회지
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    • 제22권3호
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    • pp.65-73
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    • 2018
  • 석탄층 메탄가스는 압력에 따라 비선형적인 탈착곡선을 보이므로 이를 고려하여 적절한 생산시스템이 구성되어야 한다. 석탄층 메탄가스 생산설비의 용량 및 규격은 시스템의 경계조건인 탄층 내 가스 유량과 압력조건에 의해 결정되며 이러한 특성을 분석하는 것은 가스 생산 증진을 위해 필수적이다. 본 연구를 위해 대표적인 미국 CBM 상용가스전인 San Juan 지역의 저류전산 모델을 구성하여 가스 유입방정식을 산출하였고, 이를 전체 생산시설의 경계조건으로 활용하였다. 또한 생산시설 내 가스 유량에 따른 압력감소의 영향을 분석하기 위해 생산설비 유동 분석시뮬레이터를 이용하여 노달분석을 수행하여 생산시설의 적정 규격 및 운영조건을 결정하였다. 이를 통해 석탄층 메탄가스 가스전의 최적 수송, 생산 및 포집시스템 설계 기준을 제시하였다.

Treatment outcomes of extended-field radiation therapy for thoracic superficial esophageal cancer

  • Lee, Doo Yeul;Moon, Sung Ho;Cho, Kwan Ho;Kim, Tae Hyun;Kim, Moon Soo;Lee, Jong Yeul;Suh, Yang-Gun
    • Radiation Oncology Journal
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    • 제35권3호
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    • pp.241-248
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    • 2017
  • Purpose: To evaluate the efficacy and safety of extended-field radiation therapy for patients with thoracic superficial esophageal cancer (SEC). Materials and Methods: From May 2007 to October 2016, a total of 24 patients with thoracic SEC (T1a and T1b) who underwent definitive radiotherapy and were analyzed retrospectively. The median total radiotherapy dose was 64 Gy (range, 54 to 66 Gy) in conventional fractionation. All 24 patients received radiotherapy to whole thoracic esophagus and 23 patients received elective nodal irradiation. The supraclavicular lymph nodes, the celiac lymph nodes, and both of those nodal areas were included in 11, 3, and 9 patients, respectively. Results: The median follow-up duration was 28.7 months (range 7.9 to 108.0 months). The 3-year overall survival, local control, and progression-free survival rates were 95.2%, 89.7%, and 78.7%, respectively. There were 5 patients (20.8%) with progression of disease, 2 local failures (8.3%) and 3 (12.5%) regional failures. Three patients also experienced distant metastasis and had died of disease progression. There were no treatment-related toxicities of grade 3 or higher. Conclusion: Definitive extended-field radiotherapy for thoracic SEC showed durable disease control rates in medically inoperable and endoscopically unfit patients. Even extended-field radiotherapy with elective nodal irradiation was safe without grade 3 or 4 toxicities.

Single-Phase Self-Excited Induction Generator with Static VAR Compensator Voltage Regulation for Simple and Low Cost Stand-Alone Renewable Energy Utilizations Part I : Analytical Study

  • Ahmed, Tarek;Noro, Osamu;Soshin, Koji;Sato, Shinji;Hiraki, Eiji;Nakaoka, Mutsuo
    • KIEE International Transactions on Power Engineering
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    • 제3A권1호
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    • pp.17-26
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    • 2003
  • In this paper, the comparative steady-state operating performance analysis algorithms of the stand-alone single-phase self-excited induction generator (SEIG) is presented on the basis of the two nodal admittance approaches using the per-unit frequency in addition to a new state variable de-fined by the per-unit slip frequency. The main significant features of the proposed operating circuit analysis with the per-unit slip frequency as a state variable are that the fast effective solution could be achieved with the simple mathematical computation effort. The operating performance results in the simulation of the single-phase SEIG evaluated by using the per-unit slip frequency state variable are compared with those obtained by using the per-unit frequency state variable. The comparative operating performance results provide the close agreements between two steady-state analysis performance algorithms based on the electro-mechanical equivalent circuit of the single-phase SEIG. In addition to these, the single-phase static VAR compensator; SVC composed of the thyristor controlled reactor; TCR in parallel with the fixed excitation capacitor; FC and the thyristor switched capacitor; TSC is ap-plied to regulate the generated terminal voltage of the single-phase SEIG loaded by a variable inductive passive load. The fixed gain PI controller is employed to adjust the equivalent variable excitation capacitor capacitance of the single-phase SVC.

자동차 와이퍼 시스템의 유연 다물체 동역학 해석 (Flexible Multibody Dynamic Analysis of the Wiper System for Automotives)

  • 정성필;박태원;정원선
    • 대한기계학회논문집A
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    • 제34권2호
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    • pp.175-181
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    • 2010
  • 본 논문에서는 플랫 타입 블레이드를 장착한 와이퍼 시스템의 성능을 예측하기 위한 동역학 해석방법을 제시하였다. 고무 재질로 이루어진 블레이드는 비선형의 특성을 갖기 때문에, 블레이드의 동적특성을 나타내기 위하여 모달 좌표계와 절대 절점 좌표계를 이용하였다. 블레이드 단면의 굽힘 특성을 파악하기 위해 블레이드에 대한 구조 해석을 실시하였다. 해석 결과에 따라 블레이드 단면을 강체, 유연체 및 대변형체의 3 부분으로 구분하였다. 모달 좌표계와 절대 절점 좌표계를 이용하여 블레이드 단면의 유연체 및 대변형체를 표현하였다. 동역학 해석 결과를 검증하기 위해 실험을 실시하였고, 결과 비교를 통해 본 연구에서 생성한 블레이드에 대한 유연 다물체 모델의 신뢰성을 검증하였다.