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Neutral zone approach for rehabilitation in a patient who underwent mandibulotomy: A case report (하악골 이단술을 시행한 환자에서 중립대를 활용한 상하악 총의치 수복 증례)

  • Heedo Shin;Hag-Young Lee;Jee-Hwan Kim
    • The Journal of Korean Academy of Prosthodontics
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    • v.61 no.1
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    • pp.18-25
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    • 2023
  • We present the case of a 65-year-old man with maxillary and mandibular complete dentures prepared using neutral zone technique after undergoing mandibulotomy due to tonsil cancer 10 years ago. The patient had a short edentulous period; hence, there was minimal absorption of the alveolar ridge and no abnormality in the motor function of the tongue. However, the retromolar pad was located inside the hamular notch, and the posterior alveolar ridge was relatively turned inward. If the artificial teeth would have been aligned conventionally, the functional space of the tongue would have been invaded, which would have moved the tongue posteriorly thereby reducing the stability of the denture. Therefore, applying the concept of the neutral zone can be a good reference point in such cases. The neutral zone was registered using tissue conditioner, and tooth alignment was performed by making a silicone putty index. The biggest advantage of using neutral zone concept is denture stability. In this case, the neutral zone technique was applied to obtain the lingual alignment limit of the posterior teeth to avoid invasion of the tongue space by the left posterior part of the mandible. Particularly, in case of a patient in which denture stability is difficult to obtain due to absorption of the alveolar ridge, it is believed that better results can be obtained using neutral zone technique.

Phytochemical, Antidiabetic, Antioxidant, Antibacterial, Acute and Sub-Chronic Toxicity of Moroccan Arbutus unedo Leaves

  • Latifa Doudach;Hanae Naceiri Mrabti;Samiah Hamad Al-Mijalli;Mohamed Reda Kachmar;Kaoutar Benrahou;Hamza Assaggaf;Ahmed Qasem;Emad Mohamed Abdallah;Bodour Saeed Rajab;Khouloud Harraqui;Mouna Mekkaoui;Abdelhakim Bouyahya;Moulay El Abbes Faouzi
    • Journal of Pharmacopuncture
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    • v.26 no.1
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    • pp.27-37
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    • 2023
  • Objectives: Moroccan Arbutus unedo is an essential medicinal plant; however, little is known about the biological properties of its leaves mentioned in Moroccan traditional medicine. Methods: Various standard experiments were performed to evaluate the phytochemical, antidiabetic, antioxidant, antibacterial, and acute and sub-chronic toxicity characteristics of A. unedo leaves. Results: Phytochemical screening led to the identification of several phytochemical classes, including tannins, flavonoids, terpenoids, and anthraquinones, with high concentrations of polyphenols (31.83 ± 0.29 mg GAEs/g extract) and flavonoids (16.66 ± 1.47 mg REs/g extract). Further, the mineral analysis revealed high levels of calcium and potassium. A. unedo extract demonstrated significant antioxidant and anti-diabetic activities by inhibiting α-amylase (1.350 ± 0.32 g/mL) and α-glucosidase (0.099 ± 1.21 g/mL) compared to the reference drug Acarbose. Also, the methanolic extract of the plant exhibited significantly higher antibacterial activity than the aqueous extract. Precisely, three of the four examined bacterial strains exhibited substantial susceptibility to the methanolic extract . Minimum bactericidal concentration (MBC)/minimum inhibitory concentration (MIC) values indicated that A. unedo harbor abundant bactericidal compounds. For toxicological studies, mice were administered with A. unedo aqueous extract at single doses of 2,000 and 5,000 mg/kg. They did not exhibit significant abnormal behavior, toxic symptoms, or death during the 14-day acute toxicity test and the 90-day sub-chronic toxicity test periods. The general behavior, body weight, and hematological and biochemical status of the rats were assessed, revealing no toxicological symptoms or clinically significant changes in biological markers observed in the mice models, except hypoglycemia, after 90 days of daily dose administration. Conclusion: The study highlighted several biological advantages of A. unedo leaves without toxic effects in short-term application. Our findings suggest that conducting more comprehensive and extensive in vivo investigations is of utmost importance to identify molecules that can be formulated into pharmaceuticals in the future.

Comparison of physical characteristics of eggs of Trachemys scripta elegans, Pseudemys concinna, and Mauremys reevesii (붉은귀거북(Trachemys scripta elegans)과 리버쿠터(Pseudemys concinna), 국내종 남생이(Mauremys reevesii) 간 알의 외형적 특징 비교)

  • Seung-Ju Cheon;Choong-Ho Ham;Seung-Min Park;Ju-Hee Bae;Ju-Hee Lee;Seong-Ik Jo;Suk-Jin Cheon;Ha-Cheol Sung
    • Korean Journal of Environmental Biology
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    • v.41 no.2
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    • pp.138-144
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    • 2023
  • The main factor of biodiversity decline in major biological populations around the world is invasion of alien species. To protect native species, it is necessary to manage alien species. Recently, to eradicate ecosystem disturbance caused by alien species in Korea, many efforts have been made to capture individuals using nets and purchase captured individuals. However, there is no standard for classifying species due to the form of nest site or external characteristics of eggs of freshwater turtles. Thus, Mauremys reevesii eggs might be discarded due to mistaking as eggs of alien turtles. Based on more data, this study aims to compare and analyze external differences among eggs of Trachemys scripta elegans, Pseudemys concinna, and M. reevesii and use them as reference materials in the process of eradicating alien turtles. This study measured characteristics of eggs of the three turtle species. As a result of comparison, all variables of external characteristics of alien turtles and M. reevesii eggs showed significant differences. The shape of egg was also different, with eggs of T. scripta elegans and P. concinna showing a bicone shape and those of M. reevesii showing an ellipsoid shape. In conclusion, based on results of previous studies and the present study, eggs of M. reevesii, T. scripta elegans, and P. concinna are different in shape and structure. Thus, it is possible to distinguish between M. reevesii and invasive alien turtle using their eggs.

Validation of a physical activity classification table in Korean adults and elderly using a doubly labeled water method (한국 성인과 노인을 대상으로 이중표식수법을 이용한 신체활동분류표 타당도 평가)

  • Hye-Ji Han ;Ha-Yeon Jun;Jonghoon Park;Kazuko Ishikawa-Takata;Eun-Kyung Kim
    • Journal of Nutrition and Health
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    • v.56 no.4
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    • pp.391-403
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    • 2023
  • Purpose: This study evaluated the validity of a physical activity classification table (PACT) based on total energy expenditure (TEE) and physical activity level (PAL) measured using the doubly labeled water (DLW) method in Korean adults and the elderly. Methods: A total of 141 (male 70, female 71) adults and elderly were included. The reference standards TEEDLW, PALDLW were measured over a 14-day period using DLW. A 24-hour physical activity diary was kept for three days (two days during the week and one day on the weekend). PALPACT was calculated by classifying the activity type and intensity using the PACT. PALPACT was multiplied by resting energy expenditure measured by indirect calorimetry to estimate TEEPACT. Results: The mean age of the study participants was 50.5 ± 18.8 years, and the mean body mass index was 23.4 ± 3.3 kg/m2. A comparison of TEEDLW and TEEPACT by sex and age showed no significant differences. The bias, the difference between TEEDLW and TEEPACT, was male 17.3 kcal/day and female -4.5 kcal/day. The percentage of accurate predictions (values within ± 10% of the TEEDLW) of TEEPACT was 58.6% in males and 54.9% in females, with the highest prediction values in the age group 40-64 years (70.9%) in males and over 65 years (73.9%) in females. The spearman correlation coefficient (r) between TEEPACT and TEEDLW was 0.769, indicating a significant positive correlation (p < 0.001). Conclusion: In this study, the use of a new PACT for calculating TEE and PAL was evaluated as valid. A web version of the software program and a smartphone application need to be developed using PACT to make it easier to apply for research purposes.

A Study of e-RTGC Introduction Effects in the Container Terminal : Based on D Container Terminal Case Study (컨테이너터미널에서 e-RTGC의 도입효과에 관한 연구: D터미널 사례를 중심으로)

  • Choi, Hyung-Rim;Lee, Seung-Hon;Park, Yong-Sung;Kang, Moo-Hong;Kim, Hee-Yoon;Choi, Ki-Nam;Joo, Yi-Don;Ha, Jeong-Su
    • Journal of Korea Society of Industrial Information Systems
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    • v.14 no.5
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    • pp.289-296
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    • 2009
  • All over the world more and more attention is being paid to green management which enables environment-friendly sustainable development. To keep up with these global trends and in response to the government's "low carbon green growth" policy, many efforts are being made in the port and logistics in order to drastically reduce carbon emissions and save operating expenses. To this end, the engine power source of the cranes in the container terminal is being replaced with electricity from fossil fuel. Among those cranes, especially e-RTGC has been proved to be practical and excellent in its performance through many previous studies. However, no empirical study has yet been made on its introduction effects when e-RTGC has been introduced to the container terminal. In the meantime, however, many domestic container terminals have introduced e-RTGC, and so some data have been accumulated for further research. Under these circumstances, this study has tried to make an empirical study through the case study of D container terminal, checking the restriction factors to be considered at the time of eURTGC introduction, and analyzing its introduction effects and problems. We have high expectations that this study will provide key consideration factors and empirical analysis data to the decision makers who plan to introduce an e-RTGC system, and also will be used as a reference to the development direction of e-RTGC.

A Study on Derivation of Public Conflict Management Countermeasure in the Port Sector (항만분야 공공갈등 관리방안 도출에 관한 연구)

  • Ga-Hyun Kim;Se-Won Kim;Hye-Ryeong Lee
    • Journal of Navigation and Port Research
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    • v.47 no.4
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    • pp.246-255
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    • 2023
  • Public conflicts in the port sector can cause additional social costs and delay the supply of port infrastructure, which can negatively affect local industries and national competitiveness. Although the importance of conflict management in the port sector is gradually increasing, there is still no systematic conflict management countermeasure. Therefore, in this study, the limitations of the current conflict management system in the port sector were considered, and a Delphi survey was conducted targeting experts and stakeholders in the port sector and conflict management. In addition, criteria for diagnosing conflicts in the port sector, causes of conflicts, proactive management measures, and ex post solutions were derived. The results of the Delphi survey analysis showed that the biggest causes of conflict were the absence of stakeholder opinion collection, consultation, and communication tools. Preliminary conflict management measures including a public deliberation process to collect local opinions and discuss development directions before deciding on specific issues, and ex post conflict resolution measures including investigation of causes of conflicts and objective personnel management in the process of preparing alternatives (e.g., securing reliability) were determined as the most important factors. In addition, based on the results obtained in this study, conflict management techniques for each phase of the port development project were presented. These findings are expected to be used as a useful reference material to reflect the port sector, which has not been included in the "Public Institution Conflict Management Manual (2016)" of the Office for Government Policy Coordination.

Cadmium Exposure and Renal Damage in Individuals with Low Socioeconomic Status in Environmentally Vulnerable Areas (환경보건 취약지역에 거주하는 저소득 집단의 카드뮴 노출과 신장질환 영향)

  • Yong Min Cho;Hohyun Jin;Jiyun Kang;Chahun Kim;Dahee Han;Su Hyeon Kim;Seohui Han;Young-Seoub Hong;Ki-Tae Kim
    • Journal of Environmental Health Sciences
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    • v.49 no.1
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    • pp.48-56
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    • 2023
  • Background: Few studies have assessed exposure to chemicals in the context of environmental vulnerability with a focus on exposure among populations living in certain geographical areas. Objectives: This study aimed to investigate cadmium exposure levels and kidney damage indices in environmentally and socioeconomically vulnerable populations, with further subgrouping according to economic status. Methods: Four areas were selected to represent geographical vulnerability (two environmentally vulnerable populations and two socioeconomically vulnerable populations). Among them, population groups with lower socioeconomic status (SES) were separately classified. Urinary cadmium (UCd), beta2-microglobulin (β2-MG), and N-acetyl-β-D-glucosaminidase (NAG) levels were analyzed in samples from 245 residents of these four areas. Results: Geometric means of concentrations of UCd (0.97~2.02 ㎍/g creatinine) in all selected populations (N, 245; mean age, 67.8~70.9 years old) were higher than the national reference values (0.39 for adults and 0.78 ㎍/g creatinine for people in their 60s). Participants with a lower SES had higher UCd and NAG concentrations than did non-low SES participants. In the lower SES group, there was a significant association between UCd and NAG concentrations; however, there was no such correlation in the non-low SES group. Conclusions: Consistent with the findings of previous studies evaluating chemical exposure and associated health effects in specific populations, the findings of this study suggest that individuals with a low SES may be more vulnerable to exposure and related health effects.

Development of a lateral flow dipstick test for the detection of 4 strains of Salmonella spp. in animal products and animal production environmental samples based on loop-mediated isothermal amplification

  • Wirawan Nuchchanart;Prapasiri Pikoolkhao;Chalermkiat Saengthongpinit
    • Animal Bioscience
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    • v.36 no.4
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    • pp.654-670
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    • 2023
  • Objective: This study aimed to develop loop-mediated isothermal amplification (LAMP) combined with lateral flow dipstick (LFD) and compare it with LAMP-AGE, polymerase chain reaction (PCR), and standard Salmonella culture as reference methods for detecting Salmonella contamination in animal products and animal production environmental samples. Methods: The SalInvA01 primer, derived from the InvA gene and designed as a new probe for LFD detection, was used in developing this study. Adjusting for optimal conditions by temperature, time, and reagent concentration includes evaluating the specificity and limit of detection. The sampling of 120 animal product samples and 350 animal production environmental samples was determined by LAMP-LFD, comparing LAMP-AGE, PCR, and the culture method. Results: Salmonella was amplified using optimal conditions for the LAMP reaction and a DNA probe for LFD at 63℃ for 60 minutes. The specificity test revealed no cross-reactivity with other microorganisms. The limit of detection of LAMP-LFD in pure culture was 3×102 CFU/mL (6 CFU/reaction) and 9.01 pg/μL in genomic DNA. The limit of detection of the LAMP-LFD using artificially inoculated in minced chicken samples with 5 hours of pre-enrichment was 3.4×104 CFU/mL (680 CFU/reaction). For 120 animal product samples, Salmonella was detected by the culture method, LAMP-LFD, LAMP-AGE, and PCR in 10/120 (8.3%). In three hundred fifty animal production environmental samples, Salmonella was detected in 91/350 (26%) by the culture method, equivalent to the detection rates of LAMP-LFD and LAMP-AGE, while PCR achieved 86/350 (24.6%). When comparing sensitivity, specificity, positive predictive value, and accuracy, LAMP-LFD showed the best results at 100%, 95.7%, 86.3%, and 96.6%, respectively. For Kappa index of LAMP-LFD, indicated nearly perfect agreement with culture method. Conclusion: The LAMP-LFD Salmonella detection, which used InvA gene, was highly specific, sensitive, and convenient for identifying Salmonella. Furthermore, this method could be used for Salmonella monitoring and primary screening in animal products and animal production environmental samples.

Underground Facility Survey and 3D Visualization Using Drones (드론을 활용한 지하시설물측량 및 3D 시각화)

  • Kim, Min Su;An, Hyo Won;Choi, Jae Hoon
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.40 no.1
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    • pp.1-14
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    • 2022
  • In order to conduct rapid, accurate and safe surveying at the excavation site, In this study, the possibility of underground facility survey using drones and the expected effect of 3D visualization were obtained as follows. Phantom4Pro 20MP drones have a 30m flight altitude and a redundant 85% flight plan, securing a GSD (Ground Sampling Distance) value of 0.85mm and 4points of GCP (Groud Control Point)and 2points of check point were calculated, and 7.3mm of ground control point and 11mm of check point were obtained. The importance of GCP was confirmed when measured with low-cost drones. If there is no ground reference point, the error range of X value is derived from -81.2 cm to +90.0 cm, and the error range of Y value is +6.8 cm to 155.9 cm. This study classifies point cloud data using the Pix4D program. I'm sorting underground facility data and road pavement data, and visualized 3D data of road and underground facilities of actual model through overlapping process. Overlaid point cloud data can be used to check the location and depth of the place you want through the Open Source program CloudCompare. This study will become a new paradigm of underground facility surveying.

Analysis of Coordinate Change about Domestic CORS by Earthquake (지진발생으로 인한 국내 상시관측소 좌표변화 분석)

  • Kim, Min-Gyu;Park, Joon-Kyu
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.3
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    • pp.467-475
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    • 2018
  • Recently earthquakes have been increasing worldwide, and the largest earthquake of 5.8 on the Richter scale occurred on September 12, 2016 in the Gyeongju area. After the earthquake, more than 200 aftershocks have occurred from January 2017 to December 2017. The largest earthquake in 2017 was a 4.3-magnitude earthquake near Pohang on November 15. In this study, we tried to analyze the coordinate change due to the earthquake using the data of the CORS(Continuously Operating Reference Station) in Korea. In order to analyze the change of coordinates due to the earthquake in Pohang area on November 15, 2017, data processing was performed by kinematic method. And from January 2017 to December 2017, observation data of 9 stations in Korea were analyzed by relative positioning method and the change of coordinates due to earthquake was analyzed. As a result of the study, it was possible to estimate the instantaneous coordinate change due to the earthquake through the kinematic positioning, and it was suggested that there is no change in the coordinates of the domestic CORS by the relative positioning results. After the 2017 Gyeongju earthquake, aftershocks continue to occur, and it is necessary to monitor the area continuously.