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A New Ceanothane-Type Triterpenoid Saponin Isolated from Gouania leptostachya DC. var. tonkinensis Pit. and Its Underlying Anti-Inflammatory Effects

  • Nguyen Thi Hang;Nguyen Thi Bich Thu;Le Ba Vinh;Nguyen Viet Phong;Tran Van On;Ki Yong Lee
    • Journal of Microbiology and Biotechnology
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    • v.33 no.7
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    • pp.941-948
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    • 2023
  • Metabolites from medicinal plants continue to hold significant value in the exploration and advancement of novel pharmaceuticals. In the search for plants containing compounds with anti-inflammatory effects, we observed that the ethanol (EtOH) extract obtained from the aerial components of Gouania leptostachya DC. var. tonkinensis Pit. exhibited substantial suppression of nitric oxide (NO) in vitro. In a phytochemical study on an EtOH extract of G. leptostachya, 11 compounds were purified, including one unreported compound namely gouanioside A (1). Their chemical structures were unambiguously determined through the use of various spectroscopic techniques, such as 1 and 2D NMR, IR, and HR-ESI-MS, and by producing derivatives via chemical reactions. The EtOH extract, fractions, and a new compound exerted inflammatory effects by altering NO synthesis in murine RAW264.7 macrophage cells stimulated with lipopolysaccharide. The underlying inflammatory mechanism of the new compound 1 was also explored through various in vitro experiments. The results of this study indicate the potential usefulness of new compound 1 from G. leptostachya as a treatment for inflammatory diseases.

Optic foramen location on computed tomography

  • Vuong Duc Nguyen;Minh Tran Quang Le;Chuong Dinh Nguyen;Tho Thi Kieu Nguyen
    • Archives of Craniofacial Surgery
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    • v.24 no.4
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    • pp.174-178
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    • 2023
  • Background: This study aimed to identify the location of the optic foramen in relation to the anterior sphenoid sinus wall, which is essential information for surgeons in planning and performing endoscopic transnasal surgery. Methods: Computed tomography scans of 200 orbits from 100 adult patients with no abnormalities were examined. The results included the location of the optic foramen in relation to the anterior sphenoid sinus wall and the distance between them, as well as the distance from the optic foramen and the anterior sphenoid sinus wall to the carotid prominence in the posterior sphenoid sinus. Results: The optic foramen was anterior to the anterior sphenoid sinus wall in 48.5% of orbits, and posterior in the remaining 51.5%. The mean distance from the optic foramen to the anterior sphenoid sinus wall was 3.82±1.25 mm. The mean distances from the optic foramen and the anterior sphenoid sinus wall to the carotid prominence were 7.67±1.73 and 7.95±2.53 mm, respectively. Conclusion: The optic foramen was anterior to the anterior wall of the sphenoid sinus in approximately half of the orbits examined in this study, and posterior in the remaining half. The mean distance from the optic foramen to the anterior sphenoid sinus wall of the sphenoid sinus was 3.82±1.25 mm.

Genetic diversity of spotted scat (Scatophagus argus) in Vietnam based on COI genes

  • Huy Van Nguyen;Minh Tu Nguyen;Nghia Duc Vo;Nguyen Thi Thao Phan;Quang Tan Hoang
    • Fisheries and Aquatic Sciences
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    • v.25 no.12
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    • pp.637-647
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    • 2022
  • A spotted scat, Scatophagus argus, has a high nutritional value and is among Asia's most widely consumed fish species. Thua Thien Hue's consumption market considers this species to be of high economic value and requires protection and conservation of the population. However, the studies on the identification and genetic diversity of S. argus distributed in Vietnam are still lacking. Therefore, mitochondrial cytochrome c oxidase subunit I (COI) gene was utilized to distinguish different populations and investigate the genetic diversity of two populations of S. argus from Tam Giang lagoon, Thua Thien Hue province (n = 31) and Ca Mau province (n = 14). The sequencing results indicated 13 distinct haplotypes among 45 sequences. Five single nucleotide polymorphisms were observed to distinguish Hue spotted scat population. The S. argus population in Ca Mau province was higher haplotype diversity (Hd) and nucleotide diversity (π) than those of Thua Thien Hue province, which demonstrates that there are minor differences between haplotypes. There were genetic distances ranging from 0%-4% within the populations and 6.67% between the two populations. In addition to the sequencing, the comparison of morphology, biology, culture, and the growth rate was sufficient to distinguish the spotted scat S. argus in Thua Thien Hue from Ca Mau.

Social Capital and Migration: A Case Study of Rural Vietnam

  • NGUYEN, Hong Thu;LE, My Kim;NGUYEN, Thi Thuy Dung;DAO, Vu Phuong Linh;NGUYEN, Ngoc Tien
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.1
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    • pp.63-71
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    • 2022
  • To investigate the short-run effects of social capital on migration decisions of individuals in the rural areas of Vietnam, we conducted dataset mining and performed regression model analysis in the form of panel data. As control variables, we employed the variable of social capital, which is measured by an individual's network, as well as demographic characteristics of individuals and households. We discovered that when a household is in financial distress, social networks such as linkages or asking for aid from others often enhance individual capacity. Individuals with a large social network outside of their immediate area are more inclined to relocate to the location where their connectors live. Individual participation and degree of participation in the organizational community, on the other hand, have little bearing on the likelihood of migration. In addition, this research examines theories and empirical research on the relationship between social capital and migration. Based on our research findings, we have recommended some measures to boost the efficiency of social capital and migration in rural areas of Vietnam through local government solutions.

The Effect of Institutional Capability on Entrepreneurship Education: An Empirical Study of Vietnamese Universities

  • NGUYEN, Trong Luan;NGUYEN, Trung Hau;THACH, Thao Vy;TRAN, Doan Vy;HOANG, Nguyen Huong Giang;PHAM, Ngoc Phuong Trang
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.1
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    • pp.363-372
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    • 2022
  • Entrepreneurs are valuable assets for any country. Rather than being confronted with new obstacles, they should be fostered and nurtured. Entrepreneurial firms have the power to influence how we live and work, in addition to producing jobs and contributing to economic progress. Entrepreneurs have the ability to change the world by creating diversified skill sets and profitable businesses that are vital to the advancement of our economies. How does one go about being a successful business, though? More resources are believed to be needed to create entrepreneurial environments in higher education that foster progressive ideas and innovation while also providing students with the practical knowledge and skills they need to navigate the troublesome, difficult, and uncertain situations that come with owning a business. This article will outline the scales of components from which to measure variables impacting universities' ability to encourage entrepreneurial behavior among students, based on the aforementioned significance of universities. This article is based on a survey of 507 students from different universities and backgrounds in Vietnam. The research methods used are Cronbach's alpha test and Structural Equation Modeling. From the research results, it can be seen that the university's environment plays a significant role in fostering entrepreneurial behavior among students.

Critical Factors Causing Delay on State-Funded Construction Projects in Vietnam

  • Luu, Van Truong;Kim, Soo-Yong;Pham, Nguyen-The-Thanh;Nguyen, Thanh-Long;Nguyen, Tuan-Kiet
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.104-108
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    • 2015
  • Delay on State-Funded Construction Projects (SFCPs) in Dong Thap - a province in Mekong Delta of Vietnam, as many provinces of Vietnam, have caused budget overrun through many recent years. The budget-overrun situations, in turn, have deepened the delay. Identifying critical factors affecting delay SFCPs plays a key role to mitigate negative impact of delay. 134/160 questionnaires were collected from personals working for project owners, consultants, supervisors and contractors in Dong Thap Province. Convenient sampling method was used. EFA was resulted in critical 04 factors with 20 variables caused delay in SFCPs, including: "Project technic, contractor's financial capacity and adjustment role of the government", "Regulation and Policy", "Mutual benefit support and concern between the government and residents", and "Disadvantage of construction site and weather season". Reliable measures to reduce delay on SFCPs are discussed to establish legal corridors to strictly controlling the process, consider mutual benefit between the government and its residents, and evaluating construction conditions. Those measures are considered could be applied in not only Dong Thap province, but most provinces of Vietnam as well.

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Trifluralin in aquatic products: QuEChERS and Gas chromatography-tandem mass spectrometry for trace amount detection

  • Le-Thi Anh-Dao;Do Minh-Huy;Vo Hong-Phong;Nguyen Cong-Hau
    • Analytical Science and Technology
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    • v.36 no.5
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    • pp.205-215
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    • 2023
  • In the present study, an analytical method was proposed for detecting trifluralin in aquatic products at trace concentrations. The method employed QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) and gas chromatography coupled with tandem mass spectrometry (GC-MS/MS) as the sample preparation and measurement, respectively. The effect of the aqueous phase volume used in the QuEChERS was demonstrated, and the ratio of 10:10 (mL) between water and acetonitrile phase was used for 5 g of sample. Besides, dSPE using C18 and primary-secondary amine (PSA) was applied to remove the potential interferences from the food matrices, indicating no remarkable analyte loss. The linear range was built up from 0.50 ㎍ L-1 to 3.0 ㎍ L-1 (R2 = 0.9993). Other criteria, i.e., repeatability (RSDr = 0.86-1.96 %), reproducibility (RSDR = 1.09-2.01 %), and recovery (over 90 %), were in accordance with Appendix F of AOAC (2016) for method performance. Although no trifluralin was detected for the commercial samples (fish, shrimp, and breaded shrimp), the spiked samples performed favorable recoveries and precision.

Shift of Vietnamese Consumer E-purchasing Behavior During and After Covid-19 Pandemic

  • Pham Thi Cam ANH;Nguyen Mai PHUONG;Nguyen Huong GIANG;Pham Ngoc Mai LINH;Nguyen Huong GIANG
    • Journal of Distribution Science
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    • v.22 no.1
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    • pp.47-59
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    • 2024
  • Purposes: The study aimed at examining the impact of the COVID-19 pandemic on the shift of online consumer purchasing behavior and whether the new behaviors would be maintained after the epidemic season. The study also aims to investigate how online customers change based on perceived risks. Research design and Methodology: The study investigated purchasing behavior of the same 377 online Vietnamese consumers during two periods: (1) during the period of social distancing and (2) one and half year after that, allowing data to be collected in real time, so that consumers do not have to recall their behavior. Results: Purchasing behavior appeared to be more influenced by gender, age and household size. Aged consumers are more concerned about risks than those in the younger group, who only worry about the risks during the pandemic. Consumers in households with two or more people are more concerned about the risks than those living alone. Female appeared to be more influential in both during and after pandemic than male. Conclusions: The findings contribute to clarify shift of online consumer purchasing behavior, which helps business to develop effective marketing strategies and enhance their presence in the e-commerce sector.

Assessing landslide susceptibility along the Halong - Vandon expressway in Quang Ninh province, Vietnam: A comprehensive approach integrating GIS and various methods

  • Nguyen-Vu Luat;Tuan-Nghia Do;Lan Chau Nguyen;Nguyen Trung Kien
    • Geomechanics and Engineering
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    • v.37 no.2
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    • pp.135-147
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    • 2024
  • A GIS-based landslide susceptibility mapping (LSM) was carried out using frequency ratio (FR), modified frequency ratio (M-FR), analytic hierarchy process (AHP), and modified analytic hierarchy process (M-AHP) methods to identify and delineate the potential failure zones along the Halong - Vandon expressway. The thematic layers of various landslide causative factors were generated for modeling in GIS, including geology, rainfall, distance to fault, distance to road, slope, aspect, landuse, density of landslide, vertical relief, and horizontal relief. In addition, a landslide inventory along the road network was prepared using data provided by the management department during the course of construction and operation from 2017 to 2019, when many landslides were documented. The validation results showed that the M-FR method had the highest AUC value (AUC = 0.971), which was followed by the FR method with AUC = 0.961. The AUC values were 0.939 and 0.892 for the M-AHP and AHP methods, respectively. The generated LSM obtained from M-FR method classified the study area into five susceptibility classes: very low (0), low (0-1), moderate (1-2), high (2-3), and very high (3-4) classes, which could be useful for various stakeholders like planners, engineers, designers, and local public for future construction and maintenance in the study area.

Financial Development and Economic Growth: Credit Distribution in Southeast Asian Countries

  • Lan Thi Huong NGUYEN;Anh Le Dieu NGUYEN;Huyen Thanh LE;Duy Van NGUYEN
    • Journal of Distribution Science
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    • v.22 no.3
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    • pp.49-58
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    • 2024
  • Purpose: Research on financial development plays a crucial role in guiding and implementing policies for both financial development and economic growth. This study aims to evaluate the impact of financial development on the economic growth of Southeast Asian countries. Research design, data and methodology: The research utilizes data from 11 Southeast Asian countries from 2015 to 2022. Financial development data is proxied by credit distribution in private sector. Results: Based on the analysis using the FGLS model, it indicates that financial development has a positive impact on the economic growth of Southeast Asian countries. In addition, the study also examines the impact of state investment costs and FDI investment on economic growth. The results also show that foreign direct investment flows still play an important role in Southeast Asian countries (FDI has a positive impact on economic growth). State investment costs also impact economic growth, showing that the development of public investment also brings good development to countries. Conclusions: These results suggest that credit policies for financial development in general, and the development of private credit in particular, play a significant role in these countries. Building a system to promote the activities of private sector economies will help stimulate the economic development of Southeast Asian countries.