• Title/Summary/Keyword: NewWave

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Innovative Modeling of Explosive Shock Wave Assisted Drug Delivery (고에너지물질에 의한 약물 전달 시스템 연구)

  • Yoh, Jai-Ick;Kim, Ki-Hong;Lee, Kyung-Cheol;Lee, Hyun-Hee;Park, Kyoung-Jin
    • Journal of the Korean Society of Combustion
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    • v.11 no.4
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    • pp.9-13
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    • 2006
  • Recent advances in energetic materials modeling and high-resolution hydrocode simulation enable enhanced computational analysis of bio-medical treatments that utilize high-pressure shock waves. Of particular interest is in designing devices that use such technology in medical treatments. For example, the generated micro shock waves with peak pressure on orders of 10 GPa can be used for treatments such as kidney stone removal, transdermal micro-particle delivery, and cancer cell removal. In this work, we present a new computational methodology for applying the high explosive dynamics to bio-medical treatments by making use of high pressure shock physics and multi-material wave interactions. The preliminary calculations conducted by the in-house code, GIBBS2D, captures various features that are observed from the actual experiments under the similar test conditions. We expect to gain novel insights in applying explosive shock wave physics to the bio-medical science involving drug injection. Our forthcoming papers will illustrate the quantitative comparison of the modeled results against the experimental data.

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The Correlation of Pulse Wave Velocity and Atherosclerotic Risk Factor in Stroke Patients

  • Jin, Bok Hee;Han, Min Ho
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.1
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    • pp.28-34
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    • 2015
  • Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring arterial stiffness. Increased arterial stiffness measured by PWV stands for progressive arteriosclerosis and is caused by atherosclerotic risk factors. This study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to the leading risk factors for arteriosclerosis or atherosclerosis. Subjects were 114, 69 males and 45 females who are in 60's and had baPWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbA1c, total cholesterol, BSBP (brachial artery systolic blood pressure), BDBP (brachial artery diastolic blood pressure), CSBP (central artery systolic blood pressure), CDBP (central artery diastolic blood pressure), augmentation index (AIx) and diabetes mellitus. Correlation analysis between baPWV and atherosclerotic risk factor showed significant relationship in age, HbA1c, LDL cholesterol, BSBP, BDBP, CSBP, CDBP and augmentation index. baPWV was independently related to age and BSBP in multiple linear regression analysis. The group with increased arterial stiffness was independently related to BDBP in multiple logistic regression analysis. This study might be meaningful in evaluating the relationship between arterial stiffness and atherosclerotic risk factor in a new way, and be helped to make various studies for cardiovascular disease.

Energy extraction from the motion of an oscillating water column

  • Wang, Hao;Falzarano, Jeffrey M.
    • Ocean Systems Engineering
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    • v.3 no.4
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    • pp.327-348
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    • 2013
  • An Oscillating Water Column (OWC) is a relatively practical and convenient device that converts wave energy to a usable form, which is electricity. The OWC is kept inside a fixed truncated vertical cylinder, which is a hollow structure with one open end submerged in the water and with an air turbine at the top. This research adopts potential theory and Galerkin methods to solve the fluid motion inside the OWC. Using an air-water interaction model, OWC design for energy extraction from regular wave is also explored. The hydrodynamic coefficients of the scattering and radiation potentials are solved for using the Galerkin approximation. The numerical results for the free surface elevation have been verified by a series of experiments conducted in the University of New Orleans towing tank. The effect of varying geometric parameters on the response amplitude operator (RAO) of the OWC is studied and modification of the equation for evaluating the natural frequency of the OWC is made. Using the model of air-water interaction under certain wave parameters and OWC geometric parameters, a computer program is developed to calculate the energy output from the system.

Development and Application of Penetration-type Bender Elements Probe for Stiffness Measurements of Soft Soils (연약지반의 강성도 측정을 위한 관입형 벤더 엘리먼트 프로브의 개발 및 적용)

  • Mok, Young-Jin;Jung, Jae-Woo;Kim, Hak-Sung
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.119-126
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    • 2008
  • Ground stiffness(shear wave velocity) is one of the key parameters in geotechnical earthquake engineering. An In-situ seismic technique has its own advantages and disadvantages over the others in stiffness measurements. By combining the crosshole and seismic cone techniques and utilizing favourable features of bender elements, a new hybrid probe has been developed in order to enhance data quality and easiness of testing. The basic structure of the probe, called "MudFork", is a fork composed of two blades, on each of which source and receiver bender elements were mounted respectively. To evaluate the disturbance caused by the penetration of the probe, shear wave velocity measurements were carried out in the Kaolinite slurry in the laboratory. Finally, the probe was penetrated in coastal mud near Incheon, Korea, using SPT(standard penetration test)rods pushed with a routine boring machine and shear wave velocity measurements were carried out. The results were verified with data from laboratory and cone testing. The performance of the probe turns out to be excellent in terms of data quality and testing convenience.

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Assessing sample disturbance of shelby tube using shear waves (전단파를 이용한 쉘비 튜브의 샘플 교란 효과 평가)

  • Yoon, Hyung-Koo;Lee, Jong-Sub;Kim, Joon-Han;Cho, Yong-Soon
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.134-141
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    • 2008
  • To evaluate the engineering properties of soil, the laboratory test always is carried out using samples obtained from the field. There are many studies to estimate the effect of sampling disturbance. The objective of this study appraises the disturbance using the shear wave velocity. The new shelby tube which three transducers are installed every 20cm interval is used. To laboratory tests, the large-scale consolidometer (calibration chamber) is used. During 1cm penetration, the shear wave velocity is measured by every transducer. The initial sampling disturbance is assessed through the velocity difference from bottom to right upside transducer. After finishing the sampling, the velocity is still measured every time to assess the soil disturbance in shelby tube itself. Through the measured velocity, the effect of disturbance is appraised. This study suggests that the sampling disturbance of shelby tube is effectively evaluated using shear wave velocity.

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Optical Millimeter-wave Signal Generation using Injection Locking Scheme (광주입 방법을 이용한 밀리미터파 신호 생성)

  • Kim, Jung-Tae
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.5
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    • pp.1076-1081
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    • 2003
  • A new technique for generating millimeter-wave signals from a semiconductor laser is presented. The method multiples the signal frequency by using optical injection of short optical pulses at a sub-harmonic of the cavity round-trip frequency to drive the laser oscillating at its resonant frequency. A 32GHz signal is generated using a multisection semiconductor laser operated under continuous wave conditions, by injection optical pulses at a repetition rate equal to the fourth subhamonic(8GHz). The generated millimeter-wave signal exhibits a large submamonic suppression ratio(>17 dB), large frequency detuning range (>300 MHz) low levels of phase-noise(-77.5 dBc/Hz), and large locking (>400 MHz)

SOP Package Modeling for RFIC (SOP RFIC 패키지 모델링)

  • 이동훈;어영선
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.36C no.11
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    • pp.18-28
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    • 1999
  • A new equivalent circuit model of package (SOP, Small Outline Package) is presented for designing radio frequency integrated circuits (RFIC). In the RF region, the paddle of a package does not work as an ideal ground. Further parasitics due to both coupling and loss have a substantial effect on MMIC. The equivalent circuit model and parameter extraction methodology for the electrical characteristics of the package are described by illustrating the SOP type packages. The accuracy of the model is evaluated by comparing the s-parameters of the commercial full-wave solver and those of HSPICE simulation with the circuit model. The proposed model shows an excellent agreement with full-wave analysis up to about 8GHz.

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Using Field Programmable Gate Array Hardware for the Performance Improvement of Ultrasonic Wave Propagation Imaging System

  • Shan, Jaffry Syed;Abbas, Syed Haider;Kang, Donghoon;Lee, Jungryul
    • Journal of the Korean Society for Nondestructive Testing
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    • v.35 no.6
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    • pp.389-397
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    • 2015
  • Recently, wave propagation imaging based on laser scanning-generated elastic waves has been intensively used for nondestructive inspection. However, the proficiency of the conventional software based system reduces when the scan area is large since the processing time increases significantly due to unavoidable processor multitasking, where computing resources are shared with multiple processes. Hence, the field programmable gate array (FPGA) was introduced for a wave propagation imaging method in order to obtain extreme processing time reduction. An FPGA board was used for the design, implementing post-processing ultrasonic wave propagation imaging (UWPI). The results were compared with the conventional system and considerable improvement was observed, with at least 78% (scanning of $100{\times}100mm^2$ with 0.5 mm interval) to 87.5% (scanning of $200{\times}200mm^2$ with 0.5 mm interval) less processing time, strengthening the claim for the research. This new concept to implement FPGA technology into the UPI system will act as a break-through technology for full-scale automatic inspection.

15kW-class wave energy converter floater design and structural analysis

  • Singh, Patrick Mark;Chen, Zhenmu;Choi, Young-Do
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.2
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    • pp.146-151
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    • 2016
  • This study concentrates on the design of floater for 15kW-class wave energy converter that extracts the ocean energy by oscillating vertically along the wave motion. The floater connects to a arm structure that connects to a hydraulic cylinder, which drives a hydraulic generator. The study mainly focuses on the structural analysis of the floater. Previous studies have been conducted using a miniature model; however, this study focuses on the size selection of the floater for a full scale model. Static structural analysis is conducted using fine numerical grids. Due to the complexity of the whole model, it is analyzed as a separate component. There are several load cases for each floater size, and they are analyzed thoroughly for stress (von-mises, shear, and normal) and deformation. The initial design was conducted by scaling up from the miniature model of the previous study, and the final design has been redesigned by changing the thickness and internal support structure shape.

Component structural analysis on 15kW class wave energy converter

  • Singh, Patrick Mark;Chen, Zhenmu;Choi, Young-Do
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.8
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    • pp.821-827
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    • 2015
  • This study concentrates on a wave energy converter with floaters that extracts the ocean's energy by moving up and down with the wave motion. The floater is connected to an arm structure, including a hydraulic cylinder that drives a hydraulic generator. This study focuses on a structural analysis of the floater unit, including arm and cylinder components, platform and jack-up system, along with spud columns. Previous studies have been conducted for miniature models for experimentation, but this study focuses on the full-scale model structural analysis. Static structural analysis is conducted using fine numerical grids. Due to the complexity of the whole model, it is analyzed in separate pieces. The floater unit, with arm and cylinder, are combined into one system. The platform is analyzed separately as a single system. There are four jack-up systems for each spud column; only one jack-up system is analyzed, as uniform loads are assumed on each system. There are several load cases for each system, all of which are analyzed thoroughly for stress (von Mises, shear, and normal) and deformation. Acceptable results were obtained for most of the components; unsafe components were redesigned.