• 약학회지
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• 제45권3호
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• pp.245-250
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• 2001

Aminoacyl tRNA synthetases of bacteria are known as potential targets for new anti-microbial agents. To isolate new inhibitors of bacterial methionyl-tRNA synthetases from natural sources, a new target-oriented screening system using whole cells which are over-expressing a target enzyme was developed. Approximately 8,000 culture broths of microorganisms from soils were tested by this screening system. Among them, ten culture broths was found to contain inhibitory activity against methionyl -tRNA synthetases of Escherichia coli. For the validation of the screening system, this new method was compared with in vitro enzymatic method. Seven out of 10 culture broths showed inhibitory activity against methionyl-tRNA synthetases of E. coli. This result showed that the new screening system was comparable to the enzyme assay. Thus we believe that our screening system as a new method can be applied for the screening of new antibiotics inhibiting bacterial methionyl-tRNA synthetases from natural products.

• 한국운동역학회지
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• 제21권2호
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• pp.153-159
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• 2011

The purpose of this study was to develop an innovative training model and method to improve the posture and motion, while pulling up during weight lifting by evaluating the problems of Korean weight lifters performing this motion. To investigate the effectiveness of the new training method substitute members of the Korean national weight lifting team performed both the original pull up technique and new pulling training technique while kinetics and kinematics were recorded. For this study, the first phase of the new training method is more appropriate than the original training with the pull up drop slow deadlift to the knee joint. For the second phase, the new training motion is deemed to be more effective than the current box deadlift motion. Also, this new motion corrects the posture as there is more anterior hip joint motion(about 10 cm) and the knee flexes to about 120 degrees. For the third phase, starting about 10cm above the knee the box snatch high pull up is identified as a more suitable training method. For the forth phase, the box top snatch method is judged to be a more effective training method than the original top snatch training method.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 추계학술대회 논문집
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• pp.209-213
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• 1997

This paper deals with sensing ability of $2^{nd}$ smart sensor that has a sensing ability of distinguish materials. We have developed new signal processing method that have distinguish different materials. We made the $2^{nd}$ smart sensor for experiment. The second type of smart sensor is HH type. We have developed a new signal processing method that can distinguish among different materials. The estimation method (RSAIIn dex) is developed for $2^{nd}$ smart sensor(HH smart sensor). Experiment and analysis are executed for estimation the new method. We estimated sensing ability of $2^{nd}$ smart sensor with RsA, method. Sensing Ability of the $2^{nd}$ smart sensor were evaluated relatively through a new RsAl method. According to frequency changing, influences of the $2^{nd}$ smart sensor are evaluated through a new recognition index RSAI. Applications of this method are for finding abnormal conditions of objects (automanufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

• Industrial Engineering and Management Systems
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• 제8권1호
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• pp.22-28
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• 2009

We consider facility layout problems, where mn facility units are assigned into mn cells. These cells are arranged into a rectangular pattern with m rows and n columns. In order to solve this cell type facility layout problem, many approximation algorithms with improved local search methods were studied because it was quite difficult to find exact optimum of such problem in case of large size problem. In this paper, new algorithms based on Simulated Annealing (SA) method with two neighborhood generation methods are proposed. The new neighborhood generation method adopts the exchanging operation of facility units in accordance with adjacent preference. For evaluating the performance of the neighborhood generation method, three algorithms, previous SA algorithm with random 2-opt neighborhood generation method, the SA-based algorithm with the new neighborhood generation method (SA1) and the SA-based algorithm with probabilistic selection of random 2-opt and the new neighborhood generation method (SA2), are developed and compared by experiment of solving same example problem. In case of numeric examples with problem type 1 (the optimum layout is given), SA1 algorithm could find excellent layout than other algorithms. However, in case of problem type 2 (random-prepared and optimum-unknown problem), SA2 was excellent more than other algorithms.

• 대한토목학회논문집
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• 제26권6D호
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• pp.961-968
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• 2006

도로의 가장자리에 설치되는 경계석과 측구는 교통사고로부터 보행자를 보호하고 강우로 인한 차량의 미끄러짐을 방지하는 중요한 구조물이다. 그러나 경계석과 측구를 시공함에 있어 대부분의 공정을 인력으로 수행하는 기존 시공법은 작업성과 시공품질, 시공비 등의 측면에서 많은 문제점을 안고 있다. 본 연구에서는 기존 시공법이 갖고 있는 많은 문제점들을 해결할 수 새로운 시공법을 개발하였다. 새로운 공법으로 시공된 경계석과 측구의 구조적인 안정성과 시공품질을 확인하기 위하여 기존공법과 신공법으로 시공된 경계석에 대해서 인발과 수평재하시험을 실시함과 동시에 기존공법과 신공법으로 시공된 측구에서 채취된 콘크리트 시편에 대해 일축압축시험도 실시하였다. 시험결과 신공법으로 시공된 경계석의 선형과 측구콘크리트의 강도는 크게 향상되었으며, 신공법으로 시공된 경계석의 인발 및 수평저항력은 기존공법으로 시공된 경우보다 각각 10.7배와 2.5배 큰 것으로 나타났다.

• 대한전기학회논문지:전력기술부문A
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• 제53권1호
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• pp.7-12
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• 2004

The role of protective relay with correct setting value is very important for the reliable operation of power : system. The setting process of a protective relay is difficult and requires hard work of calculations. Therefore, KEPCO as been using PROSET2000, a computer program system, in order to automate the setting process of protective relays in power transmission network since 2000. This system has a database and relay setting modules for each type of realy with coresponding Human and Computer Interaction(HCI). For the setting of a new type of relay, it require a new module, a HCI and a database table corresponding to the new relay. But it's update is not easy in case of new type of relay. This paper discussed the update method introducing a concept of Open Interface. It addressd a method to make a new HCI for new relay in view of object-oriented method using UML(Unified Modeling Language). Using the UML, we updated the PROSET2000. HCI screens for a new relay is generated automatically using the information of the new relay stored in the database. And, the database management module is upgraded to solve problems in manage and maintain the database in view of Open Interface.

• 한국소음진동공학회논문집
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• 제16권11호
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• pp.1149-1157
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• 2006

Donoho et al. suggested a wavelet thresholding denoising method based on discrete wavelet transform. This paper proposes an improved denoising method using a new thresholding function based on translation-invariant wavelet for underwater acoustic measurement. The conventional wavelet thresholding denoising method causes Pseudo-Gibbs phenomena near singularities due to the lack of translation-invariant of the wavelet basis. To suppress Pseudo-Gibbs phenomena, a denoising method combining a new thresholding function based on the translation-invariant wavelet transform is proposed in this paper. The new thresholding function is a modified hard-thresholding to each node according to the discriminated threshold so as to reject unknown external noise and white gaussian noise. The experimental results show that the proposed method can effectively eliminate noise, extract characteristic information of radiated noise signals.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2000년도 춘계 학술대회 및 국제 감성공학 심포지움 논문집 Proceeding of the 2000 Spring Conference of KOSES and International Sensibility Ergonomics Symposium
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• pp.157-162
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• 2000

Discriminant analysis is a method to relate whether the objects have a specific characteristic or not with their 'continuous' attribute values and, for given objects, to estimate whether they have a specific characteristic or not by their values of discriminant scores gotten from their attribute values. The author developed the new 'computational' method of discriminant analysis without specific hypotheses or assumptions and, by this new method, we can find 'feasible' solutions under the conditions required by our actual problems. In this paper, the author tried to apply this new method to the discrimination of logical relations. If this trial could be a success, we can apply this new method of discriminant analysis to the problems about relating the specific characteristic of the objects with their 'discrete' attribute values. The result was successful and the applicability of discriminant analysis could be expanded as a method for constructing the models for "estimating impressions".

• 한국항해학회지
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• 제17권1호
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• pp.17-29
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• 1993

The new flexible controlling method integrated with some existing maneuvers of reducing a great head way during approaching a pilot station or anchor berth, namely , Super Rudder (Woo) controlling method originally was developed. The conclusions of this paper are drawn. 1) Super Rudder (Woo) controlling method has the shortest distance along base course and distance off base course among all reducing maneuvers including Rudder Cycling. 2) This new method is flexibly adjustable to a range of yaw angles 5-35 degrees either ship's side depending on traffic situations, 3) This new method is versatile controlling maneuver enabling shipandlers to reduce or stop a ship's headway and to adjust the proper courses to a pilot station or anchor berth.

• Journal of applied mathematics & informatics
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• 제38권5_6호
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• pp.519-532
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• 2020

In this paper, we first propose a new total variation-based regularization model for image restoration. We next propose a fixed-point-like method for solving the new image restoration model, and then we provide convergence analysis for the fixed-point-like method. To evaluate the feasibility and efficiency of the fixed-point-like method for the new proposed total variation-based regularization model, we provide numerical experiments for several test problems.