• Title/Summary/Keyword: New Methods Development

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Development of a New Software Package for Processing and Analyzing DNA Microarray Images

  • Choi, Jin-Ho;Choi, Hee-Jun
    • Journal of Computing Science and Engineering
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    • v.4 no.4
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    • pp.350-367
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    • 2010
  • Microarray technology is an interdisciplinary technique that promises a revolutionary progress toward better health and improved quality of life. The paper focuses on the development of an efficient software package, equipped with already well-known methods; also some new methods are proposed that will allow the processing and analysis of thousands of genes on microarray images. The microarray analysis software package (called SmartArray), newly proposed in this paper verifies, through microarray analysis, dramatic changes in the mRNA, protein, and activity level in the rat retina during light deprivation, which have been demonstrated in previous biological experiments. The analysis results demonstrate that SmartArray can successfully find many changes in gene expression levels in each subarray and classify them according to their significance.

Fuzzy Project Scheduling of the R&D System under the Mechatronics Environment (메카트로닉스 환경하의 R&D System의 퍼지프로젝트 일정계획)

  • 이근희;이재성;주일권
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.14 no.24
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    • pp.169-177
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    • 1991
  • The Existing Protect schedulings are mathematical nodes upon which probability control is based. In fact, under the mechatronics environment in the new product design and development, statistical information is very poor or sometimes non-existent. Probabilistic PERT/CPM methods are not always satisfying because those methods suppose that it is possible to apply central- limit theorem and there exists a critical path which is much mart critical than all the other paths. Fuzzy project scheduling is possibility based scheduling. For this reason, the Fuzzy Project Scheduling essential to design, development and control the new product under the mechatranics environment. This paper deals with a modeling on the project scheduling which use fuzzy set theory. Fuzzy concepts in the project scheduling are shown to be very useful and easy to work with in the R & D system.

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Chlorella virus-mediated disruption of microalgal cell wall for biodiesel production (클로렐라 바이러스 매개 미세조류 세포벽 파쇄를 이용한 바이오 디젤 생산)

  • Kim, Soojin;Kim, Yeon-Soo
    • Korean Journal of Microbiology
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    • v.54 no.2
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    • pp.140-145
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    • 2018
  • The most energy-intensive processes in lipids extraction were the disruption of the cell wall of microalgae. Here, we tried to extract lipids through lysis using virus-infecting microalgae, to compare with those by the other two methods using microwave or ultrasonication. The lipids yield using viral infection was not significantly different from those using ultrasonication and microwave oven. This suggests that the same amount of lipids can be obtained with low energy and costs, as well as that microalgal lipids extraction by chlorella virus infection might provide the price competitiveness in biodiesel production even if it will be applied to mass production facilities.

Identification of Superior Polyvoltine Hybrids (polyvoltine${\times}$bivoltine) of Silkworm, Bombyx mori L.

  • Rao, C.G.P.;Chandrashekharaiah;Basha, K.Ibrahim;Seshagiri, S.V.;Ramesh, C.;Nagaraju, H.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.8 no.1
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    • pp.43-49
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    • 2004
  • Ten promising polyvoltine mulberry silkworm strains(SDMGl, SDMG2, SDMG3, SDMG4, SDMWl, SDMW2, RMWl, RMW2, RMW3 and RMW4) that are superior in quantitative and qualitative traits have been synthesized in the polyvoltine breeding laboratory of Andhra Pradesh State Sericulture Research & Development Institute, Hindupur through systematic hybridization and appropriate selection methods. After the genotypes were found homozygous for the desired traits, they have been crossed with 3 bivoltine testers $(APS8, APS4 and {NB_2}{D_4})$ and thirty new hybrid combinations were developed for the assessment of their hybrid performance. Phenotypic expressions of economically important quantitative and qualitative traits of fist filial generation were measured and subjected for statistical analysis. Evaluation Index and Subordinate Function methods were employed for the assessment of hybrid performance since they are widely used in silkworm hybrid evaluation. Total of seven poly${\times}$bivoltine combinations, which ranked high in both the methods, were selected as potential combinations for further field test. These combinations also ranked significantly higher than the control hybrid (APMl${\times}$APS8).

A Study on Concept Generation and Development for Street Furniture Design through Extracting Design Factors from the Space Design

  • In, Chi-Ho
    • Journal of the Korea Furniture Society
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    • v.22 no.3
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    • pp.183-189
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    • 2011
  • This is a study on methods for designers of furniture and products to generate and develop design concept in consideration of design and existing conditions of the space when they design street furniture. In particular, in case when they participate in a process of designing new space, this study aims to reveal methods generating strategic elements and basic ideas for designing street furniture through cases study of projects by understanding and analyzing concept of overall space design and by extracting artistic elements for deployment of specific designs. First, Design DNA, which decides overall flow of design concept of street furniture, is extracted through analyses of basic concepts of space design. Next, by applying 3V Design Process, alternatives of the concept generation are suggested through methods of storytelling and design language under the two approach methods of verbalization stage and visualization stage. Also its methods were explored through suggestion of designs by developing each idea of the respective concepts into specific design vocabulary.

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Technical Review on the Design Methods and Guidelines for fiber Reinforced Composites (건축토목용 복합재료의 국내.외 설계기준 분석)

  • Han, Bog-Kyu;Hong, Geon-Ho;Kim, Ki-Soo
    • Composites Research
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    • v.19 no.4
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    • pp.39-43
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    • 2006
  • A decade ago, the technology of strengthening structures using FRP composites was primitive, with very few publications. Nowadays, the potential growth of research is achieved to the wide recognition of the importance of this new technology. In fact, significant practical applications have been preceded and the development of design methods have been achieved. However, the specific design methods for each applications are still lack of design skills in spite of the wide applications of FRP composites in the construction industry. The purpose of this paper is to report the development of design methods for FRP-strengthened structures by technical review design methods and guidelines of fiber reinforced composites.

Master Plan for KORAIL Talent Cultivation (철도인재양성 마스터 플랜)

  • Kim Tae-Soo;Kim Soo-Young;Lee Jeong-Rae
    • Proceedings of the KSR Conference
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    • 2005.05a
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    • pp.936-941
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    • 2005
  • KORAIL Human Resources Development Center' educational system is changed according to new start KORAIL. So, New master plan for will perform new vision POWER KORAIL 2010 is presented. 'C' Learning, 'W' Learning and 'E' Learning form the basis of these new methods and their principles have been applied ever since. These three independent yet interconnected learning axis were formed in order to achieve balance and harmony, realized in an integrated educational community. This model of education has become the foundation of our educational ideal at KORAIL's HRD Center. Innovative thinking and diligent scrutiny of educational applications and methods at the KORAIL HRD Center will bring about winning 'the war for talent'.

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Development of Gun Fire Control System for the FFX-I Program (차기호위함 전투체계용 함포 사격제원계산장치 개발)

  • Suh, Tae-Il;Kim, Eui-Jin
    • Journal of the Korea Institute of Military Science and Technology
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    • v.16 no.6
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    • pp.752-761
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    • 2013
  • A new gun fire control system has been developed for the Korean next generation frigate class. The engineering requirement was far more tightened than the PKG-A class for the firing range availability and gun control function since 5 inch gun is adopted for the new ship. We mention about the principal technologies required to build a generic gun fire control system and proposed methods for the new gun fire control system. The new system has been designed based on the proposed methods in order to satisfy the requirement and functionality has been proved to be acceptable through the sea trial by Korean navy.

Improvement of the Robustness Bounds of the Linear Systems with Structured Uncertainties (구조화된 불확실성의 비선형요소를 갖는 선형 시스템의 강인영역 개선)

  • Jo, Jang-Hyen
    • Journal of the Korean Society for Precision Engineering
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    • v.18 no.1
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    • pp.171-179
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    • 2001
  • The purpose of this paper is the derivation and development of the new definitions and methods for the new estimation of robustness for the systems having structured uncertainties. This proposition adopts the theoretical analysis of the Lyapunov direct methods, that is, the sign properties of the Lyapunov function derivative integrated along finite intervals of time, in place of the original method of the sign properties of the time derivative of the Lyapunov function itself. This is the new sufficient criteria to relax the stability condition and is used to generate techniques for the robust design of control systems with structured perturbations. The systems considered are assumed to be nominally linear, with time-variant, nonlinear bounded perturbations. This new techniques demonstrate the improvement of robustness bounds from the numerical results.

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A Study on the Intention to use the Artificial Intelligence-based Drug Discovery and Development System using TOE Framework and Value-based Adoption Model (TOE 프레임워크와 가치기반수용모형 기반의 인공지능 신약개발 시스템 활용의도에 관한 실증 연구)

  • Kim, Yeongdae;Lee, Won Suk;Jang, Sang-hyun;Shin, Yongtae
    • Journal of Information Technology Services
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    • v.20 no.3
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    • pp.41-56
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    • 2021
  • New drug discovery and development research enable clinical treatment that saves human life and improves the quality of life, but the possibility of success with new drugs is significantly low despite a long time of 14 to 16 years and a large investment of 2 to 3 trillion won in traditional methods. As artificial intelligence is expected to radically change the new drug development paradigm, artificial intelligence new drug discovery and development projects are underway in various forms of collaboration, such as joint research between global pharmaceutical companies and IT companies, and government-private consortiums. This study uses the TOE framework and the Value-based Adoption Model, and the technical, organizational, and environmental factors that should be considered for the acceptance of AI technology at the level of the new drug research organization are the value of artificial intelligence technology. By analyzing the explanatory power of the relationship between perception and intention to use, it is intended to derive practical implications. Therefore, in this work, we present a research model in which technical, organizational, and environmental factors affecting the introduction of artificial intelligence technologies are mediated by strategic value recognition that takes into account all factors of benefit and sacrifice. Empirical analysis shows that usefulness, technicality, and innovativeness have significantly affected the perceived value of AI drug development systems, and that social influence and technology support infrastructure have significant impact on AI Drug Discovery and Development systems.