• Journal of Power Electronics
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• v.13 no.5
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• pp.884-895
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• 2013

In this paper, the Fourier-based PLL (Phase-locked Loop) is introduced with a new structure, capable of selective harmonic detection in single and three-phase systems. The application of the FB-PLL to harmonic detection is discussed and a new model applicable to three-phase systems is introduced. An analysis of the convergence of the FB-PLL based on a linear model is presented. Simulation and experimental results are included for performance analysis and to support the theoretical development. The decomposition of an input signal in its harmonic components using the Fourier theory is based on previous knowledge of the signal fundamental frequency, which cannot be easily implemented with input signals with varying frequencies or subjected to phase-angle jumps. In this scenario, the main contribution of this paper is the association of a phase-locked loop system, with a harmonic decomposition and reconstruction method, based on the well-established Fourier theory, to allow for the tracking of the fundamental component and desired harmonics from distorted input signals with a varying frequency, amplitude and phase-angle. The application of the proposed technique in three-phase systems is supported by results obtained under unbalanced and voltage sag conditions.

• Proceedings of the KSPS conference
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• 2007.05a
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• pp.3-23
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• 2007

King Sejong the Great, his students in Jip-hyeun-jeon school and Choe Sejin, their successor of the sixteenth century, indicated Middle Korean had three distinctive pitches, low, high, and rising (phyeong-, geo-, sang-sheong). Thanks to $Hun-min-jeng-{\emptyset}eum$ as well as its Annotation and side-dots literatures in fifteenth and sixteenth centuries, we can compare Middle Korean with Hamgyeong dialect, Gyeongsang dialect, and extant tone dialects with joint preservers of what was probably the tonal system of unitary mother Korean language. What is most remarkable about middle Korean phonetic work is its manifest superiority in conception and execution as anything produced in the present day linguistic scholarship. But at this stage in linguistics, prior to the technology and equipment needed for the scientific analysis of sound waves, auditory description was the only possible frame for an accurate and systematic classification. And auditory phonetics still remains fundamental in pitch description, even though modern acoustic categories may supplement and supersede auditory ones in tonological analysis. Auditory phonetics, however, has serious shortcoming that its theory and practice are too subject to be developed into the present century science. With joint researchers, I am developping a new pitch scale. It is a semiautomatic auditory grade pitch analysis program. The result of our labor will give a significant breakthrough to upgrade our component in linguistics.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2006.04a
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• pp.109-120
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• 2006

Alzheimer's disease (AD) is an age-related neurodegenerative disorder. The pathological hallmarks of AD are senile plaques and neurofibrillary tangles in the brain. Major component of senile plaques is amyloid beta peptide(A$\beta$) which is derived from amyloid precursor protein (APP). A$\beta$ is generated through the sequential cleavage of App by $\beta$ - and $\gamma$-secretases. $\beta$-secretase excises the ectodomain of APP ($\beta$-APPs) to leave a 99-amino acid long C-terminal fragment (APP-C99-CTF) in the membrane. $\gamma$-secretase then cleaves this membrane-tethered APP-CTF within the transmembrane domain, so releasing A$\beta$ peptides and APP-intracellular domain (AICD). Thus, $\beta$- and $\gamma$-secretase are regarded to perform the key steps in the pathogenesis of AD and have become important therapeutic targets in the prevention and treatment of AD. Enormous efforts have been focused to develop the amyloid beta related drug for cure of AD becuase A$\beta$ is believed to be one of the major causes of AD. since major pharmaceutical companies in world wide base compete to develop new drug for AD, we have to be careful to choose the drug target to success the tough race. In the present talk, possible drug targets based on basic research results will be discussed. These molecules should be a good target for development of new drug for AD and be less competitive to have a good shape for world wide competition.

• Wind and Structures
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• v.17 no.6
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• pp.629-646
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• 2013

One of the most common solutions adopted to reduce vibrations of skyscrapers due to wind or earthquake action is to add external damping devices to these structures, such as a TMD (Tuned Mass Damper) or TLCD (Tuned Liquid Column Damper). It is well known that a TLCD device introduces on the structure a nonlinear damping force whose effect decreases when the amplitude of its motion increases. The main objective of this paper is to describe a Hardware-in-the-Loop test able to validate the effectiveness of the TLCD by simulating the real behavior of a tower subjected to the combined action of wind and a TLCD, considering also the nonlinear effects associated with the damping device behavior. Within this test procedure a scaled TLCD physical model represents the hardware component while the building dynamics are reproduced using a numerical model based on a modal approach. Thanks to the Politecnico di Milano wind tunnel, wind forces acting on the building were calculated from the pressure distributions measured on a scale model. In addition, in the first part of the paper, a new method for evaluating the dissipating characteristics of a TLCD based on an energy approach is presented. This new methodology allows direct linking of the TLCD to be directly linked to the increased damping acting on the structure, facilitating the preliminary design of these devices.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3359-3362
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• 2014

Increasing attention is being devoted to the mechanisms by which cells receive signals and then translate these into decisions for growth, death, or migration. Recent findings have presented significant breakthroughs in developing a deeper understanding of the activation or repression of target genes and proteins in response to various stimuli and of how they are assembled during signal transduction in cancer cells. Detailed mechanistic insights have unveiled new maps of linear and integrated signal transduction cascades, but the multifaceted nature of the pathways remains unclear. Although new layers of information are being added regarding mechanisms underlying ovarian cancer and how polymorphisms in VDR gene influence its development, the findings of this research must be sequentially collected and re-interpreted. We divide this multi-component review into different segments: how vitamin D modulates molecular network in ovarian cancer cells, how ovarian cancer is controlled by tumor suppressors and oncogenic miRNAs and finally how vitamin D signaling regulates miRNA expression. Intra/inter-population variability is insufficiently studied and a better understanding of genetics of population will be helpful in getting a step closer to personalized medicine.

• Journal of the Korean Vacuum Society
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• v.12 no.3
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• pp.182-192
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• 2003

A new Monte Carlo (MC) simulator for electron beam lithography process in the multi-layer resists and compound semiconductor substrates has been developed in order to fabricate and develop the high-speed PHEMT devices for millimeter-wave frequencies. For the accurate and efficient calculation of the transferred and deposited energy distribution to the multi-component and multi-layer targets by electron beams, we newly modeled for the multi-layer resists and heterogeneous multi-layer substrates. By this model, the T-shaped gate fabrication process by electron beam lithography in the PHEMT device has been simulated and analyzed. The simulation results are shown along with the SEM observations in the T-gate formation process, which verifies the new model in this paper.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.10
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• pp.32-39
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• 2009

Most mobile devices provide limited input interfaces in order to maximize the mobility and the portability. In this paper, the author proposes a small cubic-shaped tangible input interface which tracks the location, the direction, and the velocity using MEMS sensor technology to overcome the physical limitations of the poor input devices in mobile computing environments. As the preliminary phase for implementing the proposed tangible input interface, the prototype design and implementation methods are described in this paper. Various experiments such as menu manipulation, 3-dimensional contents control, and sensor data visualization have been performed in order to verify the validity of the proposed interface. The proposed tangible device enables direct and intuitive manipulation. It is obvious that the mobile computing will be more widespread and various kinds of new contents will emerge in near future. The proposed interface can be successfully employed for the new contents services that cannot be easily implemented because of the limitation of current input devices. It is also obvious that this kind of interface will be a critical component for future mobile communication environments. The proposed tangible interface will be further improved to be applied to various contents manipulation including 2D/3D games.

• Journal of The Korean Society of Agricultural Engineers
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• v.56 no.5
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• pp.29-36
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• 2014

The purpose of this study is to improve the Generic Agricultural Systems Simulator (GASS) which can simulate various rural systems based on object-oriented model. GASS provides the configuration platform of various system components to simplify integrated agricultural system models such as irrigation systems for rice farming. The new connection and communication modules of GASS improve applicability for modelling diverse systems. The geometric connection of GASS replaces topological connection, and communication protocols expand to analyze not only homogeneous system but also heterogeneous system. In this paper, we applied GASS2 to simulate the water heights of linked tanks and the simulation outputs were verified through comparing with analytical solutions of differential equations. The two new modules make it possible to analyze the 4-tank problem which includes topological and heterogenous issues with GASS2.

• Structural Engineering and Mechanics
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• v.12 no.5
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• pp.541-558
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• 2001

The design specifications of guard fences in Japan were reexamined and the revised specifications were implemented from April 1999. Because of the huge consumption in time and cost to test the performances of full-scale guard fences in the field, some assumptions are adopted while modifying the design specifications, and numerical analyses are necessary to confirm the impact performance and safety level of new types of steel highway guard fences. In this study, the finite element models are developed for the heavy trucks and steel highway guard fences to reenact their behaviors, and the solution approach is carried out using nonlinear dynamic analysis software of structures in three dimensions (LS-DYNA). The numerical simulation results are compared with the full-scale on-site testing results to verify the proposed analysis procedure. The collision process is simulated and it is also made possible to visualize the movement of the truck and the performances of guard fences. In addition, the energy shift of the truck kinetic energy to the truck and guard fence Internal energy, and the energy absorption of each guard fence component are studied for the development of a new design methodology of steel highway guard fences based on the energy absorption capacity.

• New & Renewable Energy
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• v.18 no.1
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• pp.35-45
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• 2022

The renewable energy based MG is becoming one of the prominent solutions for greenhouse gas and constructing less power lines. However, how to procure the economics of MG considering the CO₂ emission and utility network impact is one of major issues as the proportion of renewable resource increases. This paper proposes the feasibility study scheme of campus MG and shows that the LCOE and CO₂ emission can be reduced by utilizing the excess power and introducing hydrogen system and plus DR. For this, the three cases: (a) adding the PV and selling excess power to utility, (b) producing and selling hydrogen using excess power, and (c) participating in plus DR are considered. For each case, not only the topology and component capacity of MG to secure economic feasibility, but also CO₂ emission and utility network effects are derived. If an electrolyzer with a capacity of 400 kW participates in plus DR for 3,730hours/year, the economic feasibility is securable if plus DR settlement and hydrogen sale price are more than 7.08¢/kWh and 8.3USD/kg or 6.25¢/kWh and 8.6USD/kg, respectively. For this end, continuous technical development and policy support for hydrogen system and plus DR are required.