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Clinical efficacy of ranicef$\circledR$ in the treatment of empyema thoracis (농흉에 대한 Ranicef 투여의 임상 효과)

  • Choe, Se-Yeong;Yu, Yeong-Seon
    • Journal of Chest Surgery
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    • v.23 no.5
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    • pp.894-898
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    • 1990
  • Ranicef\ulcorner[Cefpimizole sodium] is a new semisynthetic cephalosporin C derivative, was administered to 30 patients with empyema thoracis to evaluate its efficacy from Nov. 1989 to May 1990 at Department of Thoracic & Cardiovascular Surgery, Dongsan Medical Center, Keimyung University. The results were as follows. 1. The clinical efficacy of therapy was excellent in 15 cases, effective in 11 cases and failure in 4 cases. The effectiveness rate was 86.7%, respectively. 2. Among 30 cases organisms were cultured in 19 cases and 24 clinical strains were isolated. \ulcorner-hemolytic streptococcus[5], S. epidermidis[4], Pseudomonas aeruginosa[3], E. coli[3 of 5 cases], S. aureus[3 of 4 cases] and Klebsiella pneumoniae[1 of 2 cases] were effective to Ranicef\ulcorner 3. Abnormal clinical values, a decrease in platelet was observed in 3 cases and slight increases of s-GOT/GPT in 2 cases. But they were not so severe that they improved without. There were two cases of mild gastrointestinal symptom.

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Success and Failure Factors of Technology Commercialization: A Korean Case

  • Kim, Chan-Ho;Ko, Chang-Ryong
    • Asian Journal of Innovation and Policy
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    • v.3 no.1
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    • pp.25-49
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    • 2014
  • We wanted to show the different group dynamics of factors for success and failure cases for technology commercialization in small technology-based firms. Existing studies are based on product level, project level, division level or firm level. We deal with technology level, and at small-technology-based firms. This is a longitudinal case study based on 8 cases from Korea. Our study on technology level is a first trial in success and failure studies unlike all existing studies. As a first step, we introduced new categories and factors such as technology attributes and CEO reflecting data, and especially a new concept of launch readiness level. Finally, we adopted correspondence analysis to show the group dynamics. The results are as follows; Technology factors are the most important factors. Second, resource-based factors are more critical in failure cases than success cases and technology factors are more critical to success.

Usefulness of Bone Scan for Diagnosis of Osteomyelitis in Diabetic Foot (당뇨 발 환자의 골수염 진단에 있어서 골 주사 검사의 유용성)

  • Lee, Ho-Seung;Cho, Byung-Ki;Song, Hyeong-Geun;Lee, Keon-Kook
    • Journal of Korean Foot and Ankle Society
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    • v.6 no.2
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    • pp.172-177
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    • 2002
  • Objectives: To validate usefulness of the three phase bone scan for the diagnosis of osteomyelitis in the diabetic foot with soft tissue inflammation. Materials and Methods: Fourteen diabetic feet with soft tissue inflammation were included in this study. We took the bone biopsy from the site of hot uptake on the three phase bone scan but no abnormal findings on the plain radiographs. We observed whether the bone has evidence of osteomyelitis on the patholgic findings such as inflammatory cell infiltration within bone, dead bone, new bone formation and fibrosis. Results: Thirteen of fourteen cases (92.8%) were compatible with osteomyelitis on the pathologic criteria. Inflammatory cell infiltration within bone was observed in thirteen cases, dead bone in twelve cases. new bone formation in four cases. fibrosis in eight cases. All of the four findings were observed in three cases. Conclusion: In the diabetic foot with soft tissue inflammation, the osteomyelitis should be included in differential diagnosis if the lesion reveals increased uptake on three phase bone scan, even though the lesion does not show any abnormal findings on the plain radiographs.

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The COVID-19 and Stock Return Volatility: Evidence from South Korea

  • Pyo, Dong-Jin
    • East Asian Economic Review
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    • v.25 no.2
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    • pp.205-230
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    • 2021
  • This study examines the impact of the number of coronavirus cases on regime-switching in stock return volatility. This study documents the empirical evidence that the COVID-19 cases had an asymmetric effect on the regime of stock return volatility. When the stock return is in the low volatility regime, the probability of switching to the high volatility regime in the next trading day increases as the number of cumulative cases increases. In contrast, in the high volatility regime, the effect of cumulative cases on the transition probability is not statistically significant. This study also documents the evidence that the government measures against the pandemic contribute to promoting the high volatility regime of the KOSPI during the pandemic. Besides, this study projects future stock prices through the Monte Carlo simulation based on the estimated parameters and the predicted number of the COVID-19 new cases. Under a scenario where the number of new cases rapidly increases, stock price indices in Korea are expected to be in a downward trend over the next three months. On the other hand, under the moderate scenario and the best scenario, the stock indices are likely to continue to rise.

New Classification of Polydactyly of the Foot on the Basis of Syndactylism, Axis Deviation, and Metatarsal Extent of Extra Digit

  • Seok, Hyo Hyun;Park, Ji Ung;Kwon, Sung Tack
    • Archives of Plastic Surgery
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    • v.40 no.3
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    • pp.232-237
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    • 2013
  • Background Polydactyly of the foot is one of the most frequent anomalies of the limbs. However, most classification systems are based solely on morphology and tend to be inaccurate and less relevant to surgical methods and results. The purpose of this study is to present our new classification of polydactyly of the foot, which can serve as a predictor of treatment and prognosis. Methods To find a correlation between the various morphologic traits of polydactyly of the foot and the treatment plan and outcomes, we reviewed 532 cases of polydactyly of the foot in 431 patients treated in our hospital, expanding on our previous study that described polydactyly based on the importance of metatarsal bone status and varus deformity. The records of patients were evaluated and compared with previous studies at other centers. Results Unsatisfactory results were seen in 36 cases, which included 5 cases of incomplete separation due to syndactylism, 23 cases of axis deviation, and 8 cases of remnants of extradigit metatarsal bones. The locus of the polydactyly, or the digit which was involved, did not seem to affect the final postoperative outcomes in our study. Three factors-syndactylism, axis deviation, and metatarsal extension-are the major factors related to treatment strategy and prognosis. Therefore, we developed a new classification system using three characters (S, A, M) followed by three groups (0, 1, 2), to describe the complexity of polydactyly of the foot, such as $S_1A_2M_2$. Conclusions Our new classification could provide a communicable description to help determine the surgical plan and predict outcomes.

Changes in Time Preference Caused by the COVID-19 Pandemic

  • Inyong Shin
    • East Asian Economic Review
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    • v.27 no.3
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    • pp.179-211
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    • 2023
  • This paper investigates the relationship between the spread of COVID-19 and time preference. In contrast to previous studies that compared time preferences before and during the pandemic, this study estimates time preferences during the COVID-19 period using eight surveys conducted over two years. Additionally, a regression analysis was conducted on the number of new COVID-19 cases and the time elapsed since the outbreak, with estimated time preference as the dependent variable. Despite a small sample size, statistically significant results were obtained, showing that as the number of new cases increased, time preference also increased. However, this effect diminished over time and disappeared by the end of 2021 in Japan. This may be due to the public's growing familiarity with the risks of COVID-19 and the availability of vaccines and treatments. Despite a significant increase in new cases in 2022, time preference was lower than immediately after the outbreak, and this was reflected in private investments. Immediately after the outbreak of COVID-19, private investments decreased by 12% compared to the previous year, but the investments are returning in 2022 despite the surge in the number of cases. The trend of time preference explains the trend of Japanese private investments very well.

Surgical Complications of Cerebral Arterivenous Malformation and Their Management (뇌동정맥기형의 외과적 수술합병증과 그 처치)

  • Yim, Man-Bin;Kim, Il-Man
    • Journal of Korean Neurosurgical Society
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    • v.29 no.8
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    • pp.1126-1135
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    • 2000
  • Objectives : The goal of surgical management of cerebral arteriovenous malformation(AVM) is elimination of the lesion without development of new neurological deficits. To improve the management results of cerebral AVMs in the future, this article discusses about surgical complications of the AVM and their management. Material and Methods : During the past 18 years, 116 patients with cerebral AVMs were managed by surgery. Among these cases, 7 cases died, 7 cases developed new neurological deficits, 11 cases residual AVM and 5 cases intracerebral hematoma(ICH) after surgery. The author analyzes the causes of those complications and investigates the methods to minimized those complications based on the review of the literatures. Results : One stage removal of AVM and ICH in the poor neurological state were performed in 5 of 7 death cases. Subtotal removal of ICH followed by delayed AVM surgery after recovery is regard as one method to improve the outcome of patient with large ICH. Postoperative new neurological deficits developed owing to normal perfusion pressure breakthrough(NPPB) in 3, judgement error in 2, preoperative embolization in 1 and cortical injury in 1 case(s). Proper management of NPPB, accurate anatomical knowledge and physiological monitoring during operation, and well trained skill for embolization are regard as methods to minimize those complications. Residual AVMs after surgery were noticed in 11 cases, in which unintended 6 cases due to inaccurate dissection of peripheral margin of AVM, and intended 3 cases due to massive brain swelling during operation, 1 cases due to diffuse type and 1 case due to multiple type of AVM. Accurate dissection of peripheral margin of AVM and mild hypotension during operation may help to avoid this complication. Postoperative hemorrhage occurred in 3 cases due to rupture of the residual AVM and in 2 cases due to oozing from the AVM bed. Complete resection of AVM, complete control of bleeding points at AVM bed and mild hypotension during early postoperative period are the methods to avoid this complication. Conclusion : A precise but flexible therapeutic strategy and refined skill for endovascular, radiosurgical and microsurgical techniques are required to successful treatment of cerebral AVM. Adequate timing of AVM resection, accurate anatomical knowledge, proper management of NPPB and accurate dissection of peripheral margin of AVM are the key points for avoiding complications of the AVM surgery.

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Trend of Multidrug and Extensively Drug Resistant Tuberculosis in a Tuberculosis Referral Hospital, 2001~2005 (일개 결핵병원에서 다제내성결핵과 광범위내성결핵의 추이, 2001~2005)

  • Jeon, Doosoo;Shin, Dongok;Kang, Hyungseok;Sung, Nackmoon;Kweon, Kyungsoon;Shin, Eun;Kim, Kyungsoon;Lee, Myunghee;Park, Seungkyu
    • Tuberculosis and Respiratory Diseases
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    • v.64 no.3
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    • pp.187-193
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    • 2008
  • Background: Multidrug-resistant tuberculosis (MDR-TB) and extensively drug resistant tuberculosis (XDR-TB) are serious threats to worldwide tuberculosis control, but the national burden and the trends of infectious spread are largely unknown. Methods: We retrospectively reviewed the results of drug sensitivity tests and medical records of patients that were diagnosed with culture-confirmed pulmonary tuberculosis and were admitted to the National Masan Tuberculosis Hospital between 2001 and 2005. Results: From 2001 to 2005, the proportion of MDR-TB among new cases was 9.2%, 13.8%, 16.9%, 23% and 27.0% in 2001, 2002, 2003, 2004 and 2005, respectively, and the proportion of MDR-TB among previously treated cases was 58.5%, 60.2%, 62.7%, 61.7% and 71.3% in 2001, 2002, 2003, 2004 and 2005, respectively. A significant increasing trend could be discerned for MDR-TB among both new and previously treated cases (p<0.001, p=0.002 for trend, respectively). The proportion of XDR-TB among new cases was 0%, 2.3%, 3.1%, 2.5% and 6.3% in 2001, 2002, 2003, 2004 and 2005, respectively, and the proportion of XDR-TB among previously treated cases was 9.1%, 15.7%, 17.3%, 19.9% and 19.1% in 2001, 2002, 2003, 2004 and 2005, respectively. A significant increasing trend could be discerned for XDR-TB among both new and previously treated cases (p=0.005, p<0.001 for trend, respectively). Conclusion: Both MDR-B and XDR-TB were gradually increased among both new and previously treated cases. Integrated national surveillance, including the public and private sectors, will be needed to estimate the exact status of antituberculous drug resistance.

A Study on the Waterfront and Waterfront Regional Development System and Architectural Characteristics of New Urbanism (뉴어버니즘적 수변 및 워터프론트 지역개발체계와 건축적 특성에 관한 연구)

  • Lee, Gwang-young;Kong, Jun-taek
    • Journal of the Korean Institute of Rural Architecture
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    • v.21 no.4
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    • pp.1-8
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    • 2019
  • This study organize the concept of sustainable development by compiling New-urbanism, sustainable urban regeneration and theory of development. And the framework of analysis about the planning characteristics of New Urbanistic Waterfront and urban development was derived by compiling theory of Waterfront and Waterfront city and considering prior study. This study will analyze the advanced cases at home and abroad through the analysis of the urban development and architectural characteristics analysis system of the New Urbanism Waterfront and Waterfront City Development by analyzing the advanced cases of the domestic and foreign countries through the analysis.

An Exploratory Study for the Telecommunications Service Failure Cases in South Korea (정보통신 서비스의 실패 요인: 한국의 텔레콤 서비스시장에서의 실패사례연구)

  • 안재현;권재원;김명수;이동주;이상윤;한상필
    • Journal of the Korean Operations Research and Management Science Society
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    • v.27 no.3
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    • pp.115-133
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    • 2002
  • In this paper, 15 South Korean telecommunications service failure cases were analyzed. Through the in-depth case study, 8 factors were found to be the major causes contributing to the telecommunications service failure. They were (1) ineffective marketing, (2) poor demand forecasting due to misjudgment of customer preference, (3) failure to satisfy technical specifications, (4) loss of cost advantage due to the price cut of competing services or new entry with lower price, (5) loss of utility advantage due to the increased utility of competing services or new entry with higher utility (6) decrease of market attractiveness due to change of customer preference, (7) impact of government policy, and (8) insufficient or low quality of contents. Additional analysis was done to derive managerial implications to the new telecommunications service development strategy. The findings from the paper will provide valuable Insight to the successful Implementation of new service development and service provisioning processes.