• 동의신경정신과학회지
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• 제28권4호
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• pp.381-390
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• 2017

Objectives: The purpose of this study is to study the personality traits and cognitive characteristics of the Sasang constitution by comparing the Personality Test and Neuropsychological Test. Methods: A total of 121 subjects were analyzed with the results of a Two Step Questionnaire for the Sasang Constitution Diagnosis (TS-QSCD). Among them, the Personality Tests (SPQ, EPQ, TCI) and the Neuropsychological Tests (A-VLT, CPM, Stroop-CWIT, WCST) were processed and analyzed for Soyangin, Taeeumin, Soeumin. Results: 1. In the results of the SPQ, the Soyangin showed a significantly higher score than did the Taeeumin and Soeumin in Behavior, Emotionality, Cognition, as well as the Total Score. The SPQ-C score and SPQ-T were significantly higher for Soyangin, Soeumin and Taeeumin, in that order. 2. In the results of the EPQ, the Soyangin showed a significantly higher score than did the Taeeumin and Soeumin in Extraversion - introversion. Soeumin showed a significantly higher score than did the Soyangin and Taeeumin in Neuroticism. Soyangin also showed a significantly higher score than Taeeumin in Venturesomeness. 3. For the results of the TCI, the Soyangin showed a significantly lower score than did Taeeumin and Soeumin in Harm-Avoidance, but a significantly higher score in Persistence and Self-Directedness. Soyangin and Taeeumin showed a significantly higher score than did Soeumin for the total score of Self-Directedness+Cooperativeness. 4. The results of the Computerized Neuropsychological Tests (A-VLT, CPM, Stroop-CWIT, WCST) showed no significant differences between the Sasang constitution. Conclusions: The EPQ, TCI score showed significant differences between the Sasang constitution. But the Computerized Neuropsychological Tests developed to evaluate cognitive abilities did not show differences between the constitutional individuals and showed limitations as a research tool. Further studies are needed to devise a research method for ascertaining the cognitive behavioral characteristics of the Sasang constitution.

• 생물정신의학
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• 제15권2호
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• pp.92-100
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• 2008

Objectives : The purpose of this study was to investigate 1) the neuropsychological deficits with major depressive disorder(MDD) in depressed state and 2) the changes of neuropsychological dysfunctions during depressed episodes and remitted periods in the MDD group. Methods : 12 patients with MDD and 70 normal controls who were diagnosed and classified by DSM-IV and SCID-IV interview participated in this study. The psychopathology was measured using the Hamilton rating scale for depression(HAM-D) and Brief Psychiatric Rating Scale(BPRS). The memory function, executive function, and sustained attention were measured by a trained psychologist using the Korean version of Memory Assessment Scale(K-MAS), Wisconsin Card Sorting Test(WCST), and Vigilance(VIG) and Cognitrone (COG) in Vienna Test System. After 6 weeks of treatment, we retested the cognitive tests in order to measure the cognitive functions in remitted states. Results : Patients with MDD achieved significantly lower score in sentence immediately recall, verbal memory score and total memory score of the K-MAS, total errors of the WCST, response time of Vigilance and response time at "Yes" response of Cognitrone than normal controls at baseline. After 6 weeks of medication, the psychiatric symptoms in the patient group were attenuated, and most of the neuropsychological functions including attention, memory, and frontal/executive function were improved except for response time of Cognitrone. Conclusions : This study provides evidence for distinct neuropsychological deficits in patients with MDD on their depressed states and remitted periods. The impairment on response time remains after remission, and this would be a trait marker of major depressive disorder.

• 한국방사선학회논문지
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• 제8권4호
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• pp.163-170
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• 2014

본 연구는 경도인지장애가 동반된 환자를 대상으로 뇌 자기공명영상에서 인지 영역에 대한 대뇌 피질 두께를 측정하고 신경심리검사 결과와 비교하여 신경해부학적 상관관계를 규명하고자 하였다. 이를 위하여 파킨슨병으로 최초 진단 받고 신경심리검사를 시행한 78명(경도인지장애군: 39명; 비인지장애군: 39명)과 정상인 그룹 32명을 선정하였다. 신경심리검사에서 경도인지장애군과 비인지장애군의 상관관계와 신경심리검사와 뇌 자기공명영상에서 대뇌 피질 두께의 상관관계는 독립표본 T 검증 또는 피어슨 상관분석을 실시하였으며 수집된 자료의 유의 수준은 p<0.05에서 검증하였다. 결론적으로 경도인지장애를 동반한 파킨슨병 환자는 뇌 자기공명영상에서 양측 쐐기압소엽과 우하측두엽의 대뇌 피질 두께가 통계적으로 유의하게 감소하였으며 인지 기능 평가를 위한 신경심리검사에서 시공간 기능, 언어 및 시각 기억력 기능이 저하되었다. 특히 언어 및 시각 기억력 영역에 대한 신경심리검사와 신경해부학적으로 좌측 쐐기앞소엽에서 상관관계가 있었다.

• 대한조현병학회지
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• 제23권1호
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• pp.15-28
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• 2020

Objectives: This study investigated the relationship between clock-drawing test (CDT) performance and neuropsychological functions in patients with chronic schizophrenia. Methods: Thirty-one patients with schizophrenia and 30 healthy controls participated in this study. The CDT was administered in three conditions and analyzed using both quantitative and qualitative scoring systems. Comprehensive neuropsychological tests were administered. Results: The results of the quantitative analysis showed that the schizophrenia group performed significantly worse in all three conditions of the CDT compared with the control group. However, no significant differences were observed between the two groups, when the IQ and educational level were controlled. The qualitative analysis showed that the schizophrenia group exhibited significantly more errors in "graphic difficulty" compared with the control group. In addition, CDT quantitative scores were significantly correlated with visuospatial function, memory, attention and executive functions in patients with schizophrenia. Conversely, each qualitative error type was correlated with specific cognitive domains. Furthermore, "graphic difficulty" and "spatial/planning deficit" were identified as predictors of depression symptoms in patients with schizophrenia. Conclusion: The present study demonstrated that the CDT is useful for assessing cognitive dysfunctions in patients with schizophrenia, while qualitative analyses provide more specific information about cognitive deficits compared with quantitative analyses.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제8권2호
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• pp.217-231
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• 1997

본 연구에서는 ADHD의 원인론에 대한 다양한 신경학적 이론들을 살펴본 후, ADHD 진단에 널리 사용되는 신경심리학적 평가방법들에 대한 국내, 외 연구결과들을 고찰하였다. ADHD 아동들이 여러 주의력 검사상에서 일관성있게 경계력, 지속적 주의력, 주의산만성, 주의력의 분할과 조절에 문제를 보이고 있고, 실행 능력과 작동기억외에 연합기억에서도 어려움을 보이는 것으로 나타났다. 이러한 신경심리학적 검사결과는 ADHD 아동이 전두엽외에 망상활성체계 등 두뇌의 여러 부위를 포함하는 신경망에 장애가 있을 가능성을 시사해주는 것으로 생각된다. 그러나 국내에서 ADHD 아동들에게 널리 사용되고 있는 신경심리검사들은 대부분 외국에서 제작된 것이므로, ADHD 아동들의 수행결과를 보다 정확하게 비교하고 해석하기 위해서는 ADHD와 정상 아동, 그리고 기타 소아정신과장애 아동들을 대상으로 그러한 신경심리검사들에 대한 연령별 규준 확립과 타당도 검증을 위한 한국 표준화연구가 조만간 이루어져야 하겠다.

• Clinical and Experimental Pediatrics
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• 제55권10호
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• pp.383-387
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• 2012

Purpose: Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE. Methods: In total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological tests including the Korean versions of the Wechsler intelligence scale for children III, frontal executive neuropsychological test, rey complex figure test, Wisconsin card sorting test, attention deficit diagnostic scale, and child behavior checklist scale. Results: The study subjects included 13 boys and 10 girls aged $9.0{\pm}1.6$ years. Our subjects showed an average monthly seizure frequency of $0.9{\pm}0.7$, and a majority of them had focal seizures (70%). The spike index (frequency/min) was $4.1{\pm}5.3$ (right) and $13.1{\pm}15.9$ (left). Of the 23 subjects, 9 showed frequent spikes (>10/min) on the EEG. The subjects had normal cognitive and frontal executive functions, memory, and other neuropsychological sub-domain scores, even though 8 children (35%) showed some evidence of learning difficulties, attention deficits, and aggressive behavior. Conclusion: Our data have limited predictive value; however, these data demonstrate that although BRE appears to be benign at the onset, children with BRE might develop cognitive, behavioral, and other psychiatric disorders during the active phase of epilepsy, and these problems may even outlast the BRE. Therefore, we recommend scrupulous follow-up for children with BRE.

• 센서학회지
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• 제26권2호
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• pp.128-134
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• 2017

Until now, neuropsychological tests can diagnose the brain dysfunction, however, cannot distinguish the objective data of experiment enough to distinguish the relationships between brain dysfunction and cerebropathia. In this paper, an automatic cognitive test equipment system with 6-axis motion sensors was proposed for the automation of neuropsychological tests. Fist-Edge-Palm(FEP) test and Go-no go test were used to evaluate motor programming of frontal lobe. The motion data from the specially designed motion glove are transmitted wirelessly to a computer to detect the gestures automatically. The healthy 20 and 11 persons are investigated for the FEP and Go-No go test, respectively. The recognition rates of gestures of FEP and Go-No go test are min. 91.38% and 89.09%. In conclusion, the automations of cognitive tests are successful to diagnose the brain diagnostics quantitatively.

• 수면정신생리
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• 제5권2호
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• pp.134-154
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• 1998

This paper first reviewed the definition, criteria, and neurological theories concerning the etiology of AD/HD, and the empirical studies dealing with the comorbidity of AD/HD with other psychiatric disorders. Secondly, results of studies using various neuropsychological tests for assessing the cognitive and behavioral problems in AD/HD children were examined, which suggest the possibility that dysfunction may exist in neural pathways involving many areas of the brain in AD/HD. However, because most of neuropsychological test used in Korea for ADHD children had been developed abroad, further study involving AD/HD, normal control, and other psychiatric control groups is needed to obtain developmental norms for interpreting the results, and to make more accurate diagnosis, and to clarify comorbidity of AD/HD with other disorders.

• 수면정신생리
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• 제4권1호
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• pp.120-128
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• 1997

Clinical neuropsychological tests were developed originally for the diagnosis of neurological and neuro-surgical diseases. Recently, these tests are being introduced to psychiatric patients. Authors had the experience to use these tests in pychiatric outpatient clinic. Results were as follows. There was a significantly increase in language and attentional function in residual schizophrenia compared to normal control. In chronic neurosis, as visuospatial function was reduced, language and attentional functions were enhanced. With these results, authors suggest that application of neuropsychological tests in psychiatric patients may be very helpful in classifying the subgroups of disease, in selecting the modality of treatment, and in expecting prognosis.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2005년도 추계 학술대회 발표논문집
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• pp.137-140
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• 2005

In this study we investigated the cognitive neuropsychological characteristics and the underlying mechanism in a letter-by-letter reading dyslexic patient after cerebral infarct of left posterior cerebral artery using fMRl, The results of cognitive neuropsychological assesment are visual perception was appropriate, and semantic categorization, picture naming and picture-word matching tasks were above83% correct, respectively. However, she was very poor in lexical decision task. The selective reading impairment is thought to result from the disruption of the left occipitotemporal region included fusiform gyrus. In fMRl results, the activation level increase din the right occipitotemporal region included fusiform gyrus compared with normal group in compensation for left impairment and more increased in pseudo word reading task than word reading on account of familiarity.