• Clinical Psychopharmacology and Neuroscience
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• v.16 no.4
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• pp.481-488
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• 2018

Preliminary studies have claimed that short term fasting would negatively affect school performance and cognition. In contrast some other studies have reported not important decline in cognition and executive function as a result of fasting. Also limited attention was generally devoted to dietetic regimens, nutritional status and body weight. Yet neuroscience and neuro-cognitive aspects of acute hunger on the electroencephalogram and differences between obese and non-obese cases is not well understood. Hence, we decided to design and perform a case study in a more controlled situation similar to reality. Therefore, we performed several examinations including subjective tests (for eating status) and objective tests (cognitive tests such as Stroop effect and Sternberg search and electroencephalogram measures such as steady-state visual evoked potential and auditory steady-state responses) for an obese and a non-obese academic case before and after a simple breakfast. The results showed that the breakfast effects on the neuro-cognitive functions depend on either obesity status, nutritional status of the case or the type of cognitive task (visual or auditory). This paper would open a new insight to answer some important questions about the neuro-cognitive implications of fasting and feeding in obese and non-obese human cases.

• Journal of Integrative Natural Science
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• v.11 no.4
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• pp.167-183
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• 2018

Electroencephalogram (EEG) recording provides a new way to support human-machine communication. It gives us an opportunity to analyze the neuro-dynamics of human cognition. Machine learning is a powerful for the EEG classification. In addition, machine learning can compensate for high variability of EEG when analyzing data in real time. However, the optimal EEG electrode location must be prioritized in order to extract the most relevant features from brain wave data. In this paper, we propose an intelligent system model for the extraction of EEG data by training the optimal electrode location of EEG in a specific problem. The proposed system is basically a fuzzy system and uses a neural network structurally. The fuzzy clustering method is used to determine the optimal number of fuzzy rules using the features extracted from the EEG data. The parameters and weight values found in the process of determining the number of rules determined here must be tuned for optimization in the learning process. Genetic algorithms are used to obtain optimized parameters. We present useful results by using optimal rule numbers and non - symmetric membership function using EEG data for four movements with the right arm through various experiments.

• Electronics and Telecommunications Trends
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• v.32 no.6
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• pp.27-39
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• 2017

A variety of medical devices are utilized to repair or help injured body functions after accidental injury(such as a traffic accident), population aging, or disease. Such medical devices are being actively researched and developed in portable form, skin patchable type, and further, implantable form. In the future, active implantable medical devices for neuro and brain sciences are expected to be developed. Active implantable medical devices that detect brain signals and control neurology for a wider understanding of human cognition and nerve functions, and for an understanding and treatment of various diseases, are being actively pursued for future use. In this paper, the core elements of implantable devices that can be applied to neuro and brain sciences are classified into electrode technologies for bio-signal acquisition and stimulation, analog/digital circuit technologies for signal processing, human body communication technologies, wireless power transmission technologies for continuous device use, and device integration technologies to integrate them. In each chapter, the latest technology development trends for each detailed technology field are reviewed.

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.161-168
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• 2021

Recently, many cognitive training programs based on digital contents have been presented, but few digital contents have been produced for children with intellectual disabilities among children with developmental disabilities. Digital contents based training programs are needed to apply remotely untact training programs rather than face-to-face apprenticeship classes for improving the cognition of children with intellectual disabilities. This study was attempted to present the new cognitive training program by analyzing concurrent validity, which was analyzed by the correlation between items by comparing with subtests of K-WISC-IV and items of game based Neuro-World cognitive training program. It was found that there are some validity by analyzing correlation between the subtests of K-WISC-IV and the items of Neuro-World program, which means that it has concurrent validity of some items of Neuro-World program. In terms of reliability, the Cronbach alpha value was 0.794, indicating that game performance of children with intellectual disabilities and the degree of level increase in each game were somewhat reliable. This is considered to be a significant result in future studies for clinical trials of cognitive training tools.

• Journal of Educational Research in Mathematics
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• v.20 no.1
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• pp.21-43
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• 2010

In this article three types of neuro-biological epistemology have been studied and applied to mathematics. Nativism or innatism is favored by many evolutionary psychologists and some mathematicians. They believe domain specific brain functions or modules, particularly language faculty and number instinct in infants. Number/mathematical cognition is a new research area and scientists try to localize areas related with mathematics. Selectionism has adopted Darwinism to synapse growth and supports neuronal regression. Mathematical creativity can be explained using selectionism. Neural constructivism has originated from J. Piaget and supports neuronal/synapse growth in children or adults if adequate exercise and practise is given. Unlike Piaget, neural constructivists accepts the importance of structured experience for the reorganization of brain. Authors opinion is all these theories of epistemology is equally important and they all give insights on how the brain and self is made.

• Therapeutic Science for Rehabilitation
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• v.1 no.1
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• pp.57-70
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• 2012

Objective : This study was to evaluate the effects of a Neurofeedback(NFB) and Computer Assisted Cognitive Rehabilitation(CACR) training to improve on cognition and affected arm function in stroke subjects. Methods : Participants were randomly allocated to three groups: NFB(n=14), CACR(n=14) and control(n=16). All groups received occupational therapy and physical therapy for 5 session 30 minutes per week during 6 weeks. Also NFB and CACR group practiced additional NeuroComp training and RehaCom training for 30 sessions 30 minutes during 6 weeks. Results were evaluated by cognition, affected arm function. Results : There were significantly increased by CACR training that outcomes of MMSE-K(p<.05). And there weren't significantly difference by NFB and CACR training that outcomes of the affected arm function. And a difference between three groups wasn't found. Conclusion : The NFB and CACR training improves cognitive function. These results suggest that NFB and CACR training is feasible and suitable for individuals with stroke.

• PNF and Movement
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• v.12 no.2
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• pp.97-106
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• 2014

Purpose: The purpose of this study was to investigate changes in EEG through attention. Concentration training and performing tasks are important factors in the improvement of motor learning ability. Methods: In the experiment, 22 healthy people were divided into two groups: the trail making test (TMT) group and the computerized neurocognitive function test (CNT) group. A one-way Neuro Harmony M test to see whether there was a significant difference among the groups. Results: The TMT group showed a significant increase in ${\alpha}$ wave, ${\alpha}$ wave sequence, and ${\beta}$ wave sequence; however, there were no significant differences in SMR wave, SMR wave sequence, and ${\beta}$ wave. The CNT group showed increases in ${\alpha}$ wave, ${\alpha}$ wave sequence, SMR wave, SMR wave sequence, and ${\beta}$ wave sequence; however, there was no significant difference in ${\beta}$ wave. In EEGs before and after two performance tasks were changed, there were significant differences in ${\beta}$ wave, SMR wave, SMR wave sequence; however, there were no significant differences in ${\alpha}$ wave sequence, ${\beta}$ wave, and ${\beta}$ wave sequence. Conclusion: Attention training and concentration training offer feedback and repetition for constant stimulus and response. Moreover, attention training and concentration training can contribute to new studies and motivation by developing fast sensory and motor skills through acceptable visual and auditory stimulation.

• Journal of Korean Critical Care Nursing
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• v.14 no.1
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• pp.50-62
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• 2021

Purpose : This study examined the effects of an integrated management program on physical function, cognitive function, and depression in patients with subacute stroke. Methods : A nonequivalent control group design was adopted. The participants were assigned to either the experimental group (n=20) or control group (n=23). The experimental group received an 8-week integrated management program and standard rehabilitation service (i.e., physical therapy and occupational therapy), while the control group received the standard rehabilitation service only. Physical function was measured as gait speed and balance ability using the Berg Balance Scale (BBS). Cognitive function was measured with neuro-behavioral cognitive status examination (NCSE), and depression was measured using the Beck Depression Inventory-II (BDI-II). Repeated measure ANOVA was used to determine changes in physical function, cognitive function, and depression over 8-weeks. Results : The interaction between group and time was significant, indicating that the experimental group showed improvement in gait speed, balance ability, cognitive function (linguistic ability, linguistic memory, reasoning), and a decrease in depression compared to the control group. Conclusion : These results indicate that the integrated management program developed herein was beneficial in restoring physical function, cognitive function, and depression in subacute stroke patients.

• Herbal Formula Science
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• v.25 no.4
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• pp.483-497
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• 2017

Background : Behavioral stress has been suggested as one of the significant factors that is able to disrupt physiological systems and cause depression as well as changes in various body systems. The stressful events can alter cognition, learning, memory and emotional responses, resulting in mental disorders such as depression and anxiety. Results : We used a restraint stress model to evaluate the alteration of behavior and stress-related blood parameter. The animals were randomly divided into two groups of five animals each group. Furthermore, we assessed the change of body weight to evaluate the locomotor activity as well as status of emotional and anxiety in mice. After 7 days of restraint stress, the body weight had significantly decreased in the restraint stress group compared with the control group. We also observed stress-associated behavioral alterations, as there was a significant decrease in open field and forced swim test, whereas the immobilization time was significantly increased in the stress group compared to the control group. We observed the morphological changes of neuronal death and microglia by immunohistochemistry and western blot. In our study restraint stress did not cause change in neuronal cell density in the frontal cortex and CA1 hippocampus region, but there was a trend for an increased COX-2 and iNOS protein expression and microglia (CD11b) in brain, which is restraint stress. Conclusion : Our study, there were significant alterations observed in the behavioral studies. We found that mice undergoing restraint stress changed behavior, confirming the increased expression of inflammatory factors in the brain.

• Journal of Oriental Neuropsychiatry
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• v.24 no.4
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• pp.419-434
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• 2013

Objectives: The object of this study is to observe the cognition and motor function recovery effects of Joojakwhan (JJW), a traditional Korean poly-herbal formula for treating various neuropsychiatric diseases such as dementia, for the mildly stroke rats, with 60 minutes of reperfusion transient middle cerebral artery occlusion (tMCAO). Methods: In the present study, 125, 250 and 500 mg/kg of JJW were orally administered, once per day for 10 continuous days 2 hours after the tMCAO. The body weight changes, infarct sizes under 2% 2, 3, 5-triphenyl tetrazolium chloride (TTC) stain, sensorimotor functions and cognitive motor behavior tests were serially monitored with cerebral caspase-3 and cleaved poly (ADP-ribose) polymerase (PARP)-immunoreactivities and histopathological changes. The effects of tMCAO on sensorimotor functions were evaluated by using of limb placing and body-swing tests, and the cognitive motor behaviors were also observed with water maze tests. Results: From the results of tMCAO, with marked decreases of body weights, disorders of sensorimotor functions increases the limb placing test scores, and decrease the numbers and percentages of body swings to the ipsilateral sides. The cognitive motor behaviors increases the distances and time to reach the escape platform which included the inhibitions of the decreases with repeated trials that were observed with focal cerebral cortex infarct volumes. In addition, the marked increases of the atrophy, numbers of degeneration, caspase-3- and PARP-immunoreactive cells around peri-infarct ipsilateral cerebral cortex were also observed in tMCAO controls when compared with the sham control rats, respectively. Conclusions: The results obtained from this study suggest that oral administrations of JJW indicate obvious cognitions and motor function recoveries of the rats with tMCAO, mild strokes, which are mediated by neuro-protective effects through known antioxidant effects of components.