• International Journal of Contents
• /
• v.11 no.1
• /
• pp.41-51
• /
• 2015

Management systems for electronic library have been developed on the basis of Client/Server or ASP framework in domestic market for a long time. Therefore, both service provider and user suffer from their high cost and effort in management, maintenance, and repairing of software as well as hardware. Recently in addition, mobile devices like smartphone and tablet PC are frequently used as terminal devices to access computers through the Internet or other networks, sophisticatedly customized or personalized interface for n-screen service became more important issue these days. In this paper, we propose a new scheme of integrated management system for electronic library based on SaaS and Web Standard. We design and implement the proposed scheme applying Electronic Cabinet Guidelines for Web Standard and Universal Code System. Hosted application management style and software on demand style service models based on SaaS are basically applied to develop the management system. Moreover, a newly improved concept of duplication check algorithm in a hierarchical evaluation process is presented and a personalized interface based on web standard is applied to implement the system. Algorithms of duplication check for journal, volume/number, and paper are hierarchically presented with their logic flows. Total framework of our development obeys the standard feature of Electronic Cabinet Guidelines offered by Korea government so that we can accomplish standard of application software, quality improvement of total software, and reusability extension. Scope of our development includes core services of library automation system such as acquisition, list-up, loan-and-return, and their related services. We focus on interoperation compatibility between elementary sub-systems throughout complex network and structural features. Reanalyzing and standardizing each part of the system under the concept on the cloud of service, we construct an integrated development environment for generating, test, operation, and maintenance. Finally, performance analyses are performed about resource usability of server, memory amount used, and response time of server etc. As a result of measurements fulfilled over 5 times at different test points and using different data, the average response time is about 62.9 seconds for 100 clients, which takes about 0.629 seconds per client on the average. We can expect this result makes it possible to operate the system in real-time level proof. Resource usability and memory occupation are also good and moderate comparing to the conventional systems. As total verification tests, we present a simple proof to obey Electronic Cabinet Guidelines and a record of TTA authentication test for topics about SaaS maturity, performance, and application program features.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.10 no.3
• /
• pp.113-122
• /
• 2007

The rapid growth of aerial survey and remote sensing technology has enabled the rapid acquisition of very large amounts of geographic data, which should be analyzed using real-time visualization technology. The level of detail(LOD) algorithm is one of the most important elements for realizing real-time visualization. We chose the triangulated irregular network (TIN) method to generate normalized digital elevation model(DEM) data. First, we generated TIN data using contour lines obtained from a two-dimensional(2D) digital map and created a 2D grid array fitting the size of the area. Then, we generated normalized DEM data by calculating the intersection points between the TIN data and the points on the 2D grid array. We used constrained Delaunay triangulation(CDT) and ray-triangle intersection algorithms to calculate the intersection points between the TIN data and the points on the 2D grid array in each step. In addition, we simulated a three-dimensional(3D) terrain model based on normalized DEM data with real-time visualization using a Microsoft Visual C++ 6.0 program in the DirectX API library and a quad-tree LOD algorithm.

• IMMUNE NETWORK
• /
• v.6 no.4
• /
• pp.185-191
• /
• 2006

Background: Based on outstanding progresses in animal experiments, vaccines for some human tumors have been developed. However, clinical effects of these vaccines have been far below than expected. This discrepancy might come from differences between animal models and human patients with respect to immunocompetency. The immune status of mice after tumor inoculation has not been well studied, which make us cautious in interpreting and applying the results from mice to human. We evaluated cell-mediated immune responses in mice after tumor cell inoculation. Methods: Mice were inoculated with TA3Ha, CT26, or 4T1. Delayed-type hypersensitivity (DTH) responses were induced 2-4 weeks after inoculation using 2,4-dinitro-1-fluorobenzene as an antigen. The relationships between the severity of DTH responses and the duration of tumor inoculation or the size of tumor mass were analyzed. Results: In T A3Ha groups, DTH response was elevated 2 weeks after inoculation, but depressed after 4 weeks, compared to the control group. When analyzed based on the sizes of tumor masses elicited, DTH responses were inversely related to the mass size, especially in those greater than 10 mm in diameter. In CT26 groups, while the duration after inoculation did not affect the severity of DTH responses, those with large mass showed depressed responses regardless the duration of inoculation. 4T1 cells grew so slowly that the size of tumor mass was small even 4 weeks after inoculation, and this group showed much higher DTH responses compared to that of tumor-free group. Conclusion: At least in an experimental setting where tumor model was induced by inoculating tumor cell lines into immunologically competent mice, the host immune response was elevated in early stage, and then depressed in late stage when the mass grew over a critical size.

• IMMUNE NETWORK
• /
• v.3 no.4
• /
• pp.310-319
• /
• 2003

Inflammatory mediators has been recognized as an important role in the pathogenesis of rheumatoid arthritis (RA). IL-17 is increasingly recognized as an important regulator of immune and inflammatory responses, including induction of proinflammatory cytokines and osteoclastic bone resorption. Evidence of the expression and proinflammatory activity of IL-17 has been demonstrated in RA synovium and in animal models of RA. However, the signaling pathways that regulate IL-17 production remain unknown. In the present study, we investigated the role of the phosphatidylinositol 3 kinase (PI3K)-Akt pathway in the regulation of IL-17 production in RA. PBMC were separated from RA (n=24) patients, and stimulated with various agents (anti CD3, anti CD28, PHA, ConA, IL-15). IL-17 levels were determined by sandwich ELISA and RT-PCR. The production of IL-17 was significantly increased in cells treated with anti-CD3 antibody, PHA, IL-15 or MCP-1 (P<0.05). ConA also strongly induced IL-17 production (P<0.001), whereas TNF-alpha, IL-1beta, IL-18 or TGF-beta did not. IL-17 was detected in the PBMC of patients with osteoarthritis (OA) but their expression levels were much lower than those of RA PBMC. Anti-CD3 antibody activated the PI3K-Akt pathway and activation of the PI3K-Akt pathway resulted in a pronounced augmentation of nuclear factor kappaB ($NF-{\kappa}B$). IL-17 production by activated PBMC in RA is completely or partially blocked in the presence of $NF-{\kappa}B$ inhibitor PDTC and PI3K-Akt inhibitor, wortmannin and LY294002, respectively. Whereas the inhibition of AP-1 and extracellular signal-regulated kinase (ERK)1/2 did not affect IL-17 production. These results provide new insight into that PI3K/Akt and $NF-{\kappa}B$ dependent signal transduction pathway could be involved in the overproduction of key inflammatory cytokine, IL-17 in rheumatoid arthritis.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• v.47 no.4
• /
• pp.71-81
• /
• 2010

In grid system, Task scheduling based on list scheduling models has showed low complexity and high efficiency in fully connected processor set environment. However, earlier schemes did not consider sufficiently the communication cost among tasks and the composition process of lightpath for communication in optical gird environment. In this thesis, we propose LSOG (Leveling Selection in Optical Grid) which sets task priority after forming a hierarchical directed acyclic graph (DAG) that is optimized in optical grid environment. To determine priorities of task assignment in the same level, proposed algorithm executes the task with biggest communication cost between itself and its predecessor. Then, it considers the shortest route for communication between tasks. This process improves communication cost in scheduling process through optimizing link resource usage in optical grid environment. We compared LSOG algorithm with conventional ELSA (Extended List Scheduling Algorithm) and SCP (Scheduled Critical Path) algorithm. We could see the enhancement in overall scheduling performance through increment in CCR value and smoothing network environment.

• IMMUNE NETWORK
• /
• v.3 no.2
• /
• pp.136-144
• /
• 2003

Oral administration of antigen has long been considered as a promising alternative for the treatment of chronic autoimmune diseases including rheumatoid arthritis (RA), and oral application of type II collagen (CII) has been proven to improve pathogenic symptoms in RA patients without problematic side effects. To further current understandings about the immune suppression mechanisms mediated by orally administered antigens, we examined the changes in IgG subtypes, T-cell proliferative response, and proportion of interleukin (IL)-10 producing Th subsets in a time course study of collagen induced arthritis (CIA) animal models. We found that joint inflammation in CIA mouse peaked at 5 weeks after first immunization with CII, which was significantly subdued in mice pre-treated by repeated oral administration of CII. Orally tolerized mice also showed increase in their serum level of IgG1, while the level of IgG2a was decreased. T-cell proliferation upon CII stimulation was also suppressed in lymph nodes of mice given oral administration of CII compared to non-tolerized controls. When cultured in vitro in the presence of CII, T-cells isolated from orally tolerized mice presented higher proportion of $CD4^+IL-10^+$ subsets compared to non-tolerized controls. Interestingly, such increase in IL-10 producing cells were obvious first in Peyer's patch, then by 5 weeks after immunization, in mesenteric lymph node and spleen instead. This result indicates that a particular subset of T-cells with immune suppressive functions might have migrated from the original contact site with CII to inflamed joints via peripheral blood after 5 weeks post immunization.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.33 no.4A
• /
• pp.352-360
• /
• 2008

Recently Task Group (TG) 4 of the Institute of Electrical and Electronics Engineers (IEEE) 802.15a has been recommended a system with ranging capability in existence of multiple Simultaneous operating piconets (SOPs) as well as low-cost, low-power. According to the ranging service, coherent and non-coherent based ranging schemes using ternary code have been adopted as a standard. However it is hard to estimate an accurate time of arrival (TOA) in case of using direct sequence based TOA estimation method because pulse repetition interval (PRI) offered by TG is more limited than the maximum excess delay (MED) of channel. To mitigate inter pulse interference (IPI) problem, this paper proposes a non-coherent TOA estimation scheme using non-periodic transmission (NPT) pattern. The proposed receiver is based on a non-coherent energy detection considering with motivation of low rate wireless personal area network (LR-WPAN). TOA information is estimated via proper comparison with a prescribed threshold after the sliding correlation and search back window (SBW) process for reducing TOA error. To verify the performance of proposed ranging scheme, two distinct channel models approved by IEEE 802.15.4a TG are considered. According to the simulation results, we could conclude that the proposed scheme have performed better performance than the conventional method on the existence of multiple SOPs.

• The Journal of Information Technology
• /
• v.4 no.3
• /
• pp.87-100
• /
• 2001

IETF has proposed integrated services model(Int-Serv) and differentiated service(Diff-Serv) to supply IP QoS in Internet[1][2]. Int-Serv model uses state information of each IP flow, so satisfies QoS according to traffic characteristics, but increases the amount of flow state information with increasing flow number. Diff-Serv uses PHP(Per Hop Behaviour) and there are well-defined classes to provide differentiated traffics with different services according to delay and loss sensitivity. Diff-Serv model can provide diverse services in Internet because of having no the state and signal information of each flow. As MPLS uses the packet forwarding technology based on label, it implements the forwarding engine of high performance easily. The MPLS can set up the path having different and variable bandwidth and assign each path to particular CoS (Class of Service). Therefore it is possible to support the Diff-Serv model of well- defined classes that can provide the differentiated traffic with different services according to delay and loss sensitivity in IP QoS models of IETF. In this paper we propose a scheme that can accommodate Diff-Serv model to provide QoS. The system performance has been estimated by scheduling plan according to traffic classes.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• v.39 no.3
• /
• pp.18-31
• /
• 2002

In this study, we introduce a concept of advanced neurofuzzy polynomial networks(ANFPN), a hybrid modeling architecture combining neurofuzzy networks(NFN) and polynomial neural networks(PNN). These networks are highly nonlinear rule-based models. The development of the ANFPN dwells on the technologies of Computational Intelligence(Cl), namely fuzzy sets, neural networks and genetic algorithms. NFN contributes to the formation of the premise part of the rule-based structure of the ANFPN. The consequence part of the ANFPN is designed using PNN. At the premise part of the ANFPN, NFN uses both the simplified fuzzy inference and error back-propagation learning rule. The parameters of the membership functions, learning rates and momentum coefficients are adjusted with the use of genetic optimization. As the consequence structure of ANFPN, PNN is a flexible network architecture whose structure(topology) is developed through learning. In particular, the number of layers and nodes of the PNN are not fixed in advance but is generated in a dynamic way. In this study, we introduce two kinds of ANFPN architectures, namely the basic and the modified one. Here the basic and the modified architecture depend on the number of input variables and the order of polynomial in each layer of PNN structure. Owing to the specific features of two combined architectures, it is possible to consider the nonlinear characteristics of process system and to obtain the better output performance with superb predictive ability. The availability and feasibility of the ANFPN are discussed and illustrated with the aid of two representative numerical examples. The results show that the proposed ANFPN can produce the model with higher accuracy and predictive ability than any other method presented previously.

• Journal of Broadcast Engineering
• /
• v.16 no.5
• /
• pp.750-761
• /
• 2011

Currently, 3DTV technologies are being developed as the future services of the HD digital broadcast environment. As one of the various research topics to apply 3DTV technologies to the conventional broadcasting network, methods to configure stereoscopic videos are being studied. In this paper, we proposed a method to broadcast high quality stereoscopic videos based on analysis of a method to add a stereoscopic descriptor to the PMT of MPEG-2 transport streams and a method to transmit stereoscopic videos by the expansion of MPEG-C part 3 which are from precedent studies. The proposed technique maintains compatibility with conventional MPEG-2 transport streams by showing only reference video for models that do not support 3D broadcasting. Therefore, the compatibility between conventional broadcasting and stereoscopic videos should make this method useful when activating 3D services in the communications and broadcasting area