• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.9
• /
• pp.4437-4446
• /
• 2013

The purpose of this study was to development and evaluate the effects of cardiocerebrovascular disease prevention program for taxi drivers on physiological variables(blood pressure, blood sugar, serum lipids) and physical variables(body fat, muscle endurance, cardiopulmonary endurance, balance). This study consisted of two phases: developing the program and evaluating its effectiveness. 1 phase, 321 taxi drivers investigated a health condition and a life habit and an educational need and developed a program with the ground which will reach. 2 phases, The effectiveness of the program was tested in October 2011, with 51 taxi driver. The experimental group was given 12 weeks period exercise 1 weeks 3 time, disease education 4 time, 2 nutrition consultations. Although there was no significant reduction in blood pressure, heart rate, blood sugar, serum lipids, there were statistically significant increases in muscle endurance (t=-7.62 p<.001), cardiopulmonary endurance (t=-3.39, p<.001), balance(t=-4.13, p<.001) and decreased body fat (t= -3.11, p<.015) in before compared to after. These findings suggest that an integrated cardiocerebro-vascular disease prevention program improves physical fitness.

• The Plant Pathology Journal
• /
• v.33 no.4
• /
• pp.393-401
• /
• 2017

Efforts to control viral diseases in crop production include several types of physical or chemical treatments; antiviral extracts of a number of plants have also been examined to inhibit plant viral infection. However, treatments utilizing naturally selected microorganisms with activity against plant viruses are poorly documented. Here we report isolation of a soil inhabiting bacterium, Pseudomonas oleovorans strain KBPF-004 (developmental code KNF2016) which showed antiviral activity against mechanical transmission of tobamoviruses. Antiviral activity was also evaluated in seed transmission of two tobamoviruses, Pepper mild mottle virus (PMMoV) and Cucumber green mottle mosaic virus (CGMMV), by treatment of seed collected from infected pepper and watermelon, respectively. Pepper and watermelon seeds were treated with culture supernatant of P. oleovorans strain KBPF-004 or control strain ATCC 8062 before planting. Seeds germinated after treatment with water or ATCC 8062 yielded about 60% CGMMV or PMMoV positive plants, whereas < 20% of KBPF-004-treated seeds were virus-infected, a significantly reduced seed transmission rate. Furthermore, supernatant of P. oleovorans strain KBPF-004 remodeled aggregation of PMMoV 126 kDa protein and subcellular localization of movement protein in Nicotiana benthamiana, diminishing aggregation of the 126 kDa protein and essentially abolishing association of the movement protein with the microtubule network. In leaves agroinfiltrated with constructs expressing the coat protein (CP) of either PMMoV or CGMMV, less full-size CP was detected in the presence of supernatant of P. oleovorans strain KBPF-004. These changes may contribute to the antiviral effects of P. oleovorans strain KBPF-004.

• Korean Journal of Social Welfare Studies
• /
• v.43 no.1
• /
• pp.389-411
• /
• 2012

A new era of research has focused on examining the growth of change in drinking problems among the elderly. Thus, the purpose of the present study was two fold: (1) to investigate trajectories of drinking problems(CAGE) among the Korean elderly(age$${\geq_-}65$$); and (2) to identify the predicting factors for the intercept and the slope of alcohol problems using multi-level growth curve model. Data come from three waves(1st wave(2006)~3rd wave(2008) of the Korea Welfare Panel(KWP) study. The results indicated that the levels of drinking problems decreased over time and that age, gender, marital status, religion, poverty, self-rated health, and social relationship satisfaction were associated with the baseline CAGE. Further analysis showed that social relationship satisfaction affected the declining slope of drinking problems over time. Specifically, among those who satisfied social relationship, there was a sharp decline of CAGE over time. Overall findings highlight the importance of developing and implementing effective alcohol prevention programs for the elderly in the community settings to mitigate the harmful effects of various psycho-social stressors. Especially, programs to maintain and form healthy social support network are suggested as critical interventions for prevention as well as recovery of alcohol problems in late life.

• Journal of the Korean Solar Energy Society
• /
• v.36 no.1
• /
• pp.63-73
• /
• 2016

How effectively a wind farm captures high market prices can greatly influence a wind farm's viability. This research identifies and creates an understanding of the effects that result in various capture prices (average revenue earned per unit of generation) that can be seen among different wind farms, in the current and future competitive SMP (System Marginal Price) market in South Korea. Through the use of a neural network to simulate changes in SMP caused by increased renewables, based on the Korea Institute of Energy Research's extensive wind resource database for South Korea, the variances in current and future capture prices are modelled and analyzed for both onshore and offshore wind power generation. Simulation results shows a spread in capture price of 5.5% for the year 2035 that depends on both a locations wind characteristics and the generations' correlation with other wind power generation. Wind characteristics include the generations' correlation with SMP price, diurnal profile shape, and capacity factor. The wind revenue cannibalization effect reduces the capture price obtained by wind power generation that is located close to a substantial amount of other wind power generation. In onshore locations wind characteristics can differ significantly/ Hence it is recommended that possible wind development sites have suitable diurnal profiles that effectively capture high SMP prices. Also, as increasing wind power capacity becomes installed in South Korea, it is recommended that wind power generation be located in regions far from the expected wind power generation 'hotspots' in the future. Hence, a suitable site along the east mountain ridges of South Korea is predicted to be extremely effective in attaining high SMP capture prices. Attention to these factors will increase the revenues obtained by wind power generation in a competitive electricity market.

• International Area Studies Review
• /
• v.13 no.2
• /
• pp.393-416
• /
• 2009

This paper explores the technology resource-based determinants influencing internationalization performance of Korean software-related new ventures. On the ground of the study by Zahra et al.(2003), this paper aims to test empirically in Korea how interaction effects of tangible and intangible technological resources, as firm capability, are related to software new ventures' internationalization performance. The test results shows that intangible technological resource represented by R&D intensity is not significantly related to internationalization performance, but reveals that intangible technological resource represented by strength of technological cooperation network and technological reputation is positively and significantly associated with internationalization performance. Internationalization performance is more significantly and positively associated with the interactions of tangible technological resource and intangible technological resource than those resources respectively. The implication for the findings in the paper is that cutting edge technological capability of software new ventures can be more closely associated with internationalization performance if those resources are fully utilized or leveraged by intangible resources acquired by cooperation with local networks and created through technological reputation of new ventures.

• International Area Studies Review
• /
• v.12 no.3
• /
• pp.293-319
• /
• 2008

Medium and small-sized venture firms as well as multinational companies pay liabilities of foreignness. We defined these costs as three different factors which are liability of handicaps(deficit of time, money, experience and, increase of financial risk), overseas market entry costs(information gathering costs, network building costs, marketing costs, channelling costs, monitoring costs), internationalization preparing costs(forecasting and market research of local markets, ex-ante cooperation with local firms), and then empirically tested how each of these factors affects on their business performances. The more important both Taiwanese and Korean firms consider liability of handicaps, the more bigger they pay overseas market entry costs(H1). On the contrary, the more important they consider overseas entry costs, the more they focus on internationalization preparation(H4) and get the better business performances(H5). The more important Korean firms consider liability of handicaps, the bigger they focus on internationalization preparation, on the contrary, the less Taiwanese firms do this(H2). Taiwanese firms as well as Korean firms rejected Hypothesis 3 and 6 which mean both liability of handicaps and internationalization preparation are no relation with their own business performances.

• Journal of Animal Science and Technology
• /
• v.60 no.12
• /
• pp.32.1-32.10
• /
• 2018

Background: Necdin (NDN), a member of the melanoma antigen family showing imprinted pattern of expression, has been implicated as causing Prader-Willi symptoms, and known to participate in cellular growth, cellular migration and differentiation. The region where NDN is located has been associated to QTLs affecting reproduction and early growth in cattle, but location and functional analysis of the molecular mechanisms have not been established. Methods: Here we report the sequence variation of the entire coding sequence from 72 samples of cattle, yak, buffalo, goat and sheep, and discuss its variation in Bovidae. Median-joining network analysis was used to analyze the variation found in the species. Synonymous and non-synonymous substitution rates were determined for the analysis of all the polymorphic sites. Phylogenetic analysis were carried out among the species of Bovidae to reconstruct their relationships. Results: From the phylogenetic analysis with the consensus sequences of the studied Bovidae species, we found that only 11 of the 26 nucleotide changes that differentiate them produced amino acid changes. All the SNPs found in the cattle breeds were novel and showed similar percentages of nucleotides with non-synonymous substitutions at the N-terminal, MHD and C-terminal (12.3, 12.8 and 12.5%, respectively), and were much higher than the percentage of synonymous substitutions (2.5, 2.6 and 4.9%, respectively). Three mutations in cattle and one in sheep, detected in heterozygous individuals were predicted to be deleterious. Additionally, the analysis of the biochemical characteristics in the most common form of the proteins in each species show very little difference in molecular weight, pI, net charge, instability index, aliphatic index and GRAVY (Table 4) in the Bovidae species, except for sheep, which had a higher molecular weight, instability index and GRAVY. Conclusions: There is sufficient variation in this gene within and among the studied species, and because NDN carry key functions in the organism, it can have effects in economically important traits in the production of these species. NDN sequence is phylogenetically informative in this group, thus we propose this gene as a phylogenetic marker to study the evolution and conservation in Bovidae.

• 재활복지
• /
• v.22 no.2
• /
• pp.127-159
• /
• 2018

The purpose of this study is to provide the useful reference to establish the system improvement plan that activates the counseling service quality for the disabled parents peer counselors. The qualitative case study method of Yin (2009) has been used to understand and reflect to the system for the experience of field counseling of the peer counselors for the disabled parents. 10 parents peer counselors for the disabled were proportionately sampled and interviewed about their experiences through a FGI and two individual interviews. The result of the study derived from total 87 abstract concepts and 17 categories and personal motivations for participating and changes from the experience are as follows: the effects of counseling are "mutual sympathy toward the same disability," "Identity transformation from nobody to somebody who gives hope," and "another social insurance and social safety network that parents disability make." The barrier facts for the parents peer counseling activation are: "problem of securing the position of the counseling site" and difficulty in finding the client due to lack of awareness and publicity. "The study suggests four programs to upgrade the parents peer counseling: (1) To secure the position of the counseling site, (2) To reestablish the status as a professional counselor. (3) The need of pokicy supplement and support from the government, (4) The expectancy of creating jobs through the conversion of full-time workers.

• Journal of Life Science
• /
• v.29 no.7
• /
• pp.809-816
• /
• 2019

The ubiquitous plant metabolite p-coumaric acid (p-CA) has antioxidant and anti-inflammatory properties, but its anti-cancer activity has not been established in gastric cancer cell lines. In this study, we investigated the effects of p-CA on the proliferation and transcriptome profile of SNU16 gastric cancer cells. Treatment with p-CA induced apoptosis of the SNU-16 cells by regulating the expression of pro-apoptotic and anti-apoptotic proteins, such as Bcl-2, poly (ADP-ribose) polymerase (PARP), Bax, procaspase-3, and cleaved-caspase-3. The genes differentially expressed in response to p-CA treatment of the SNU-16 cells were identified by RNA sequencing analysis. Genes regulated by p-CA were involved mainly in the inflammatory response, apoptotic processes, cell cycle, and immune response. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that the phosphatidylinositol-3-kinase-Akt and cancer signaling pathways were altered by p-CA. Protein-protein interaction (PPI) network analysis also revealed that p-CA treatment was correlated with differential expression of genes associated with the inflammatory response and cancer. Collectively, these results suggest that p-CA has potential utility in gastric cancer prevention.

• Management & Information Systems Review
• /
• v.37 no.4
• /
• pp.125-140
• /
• 2018

Technology cooperation is a necessary factor for small and medium sized firms to be survived and developed because small and medium sized firms can make economy scale and economy scope by new advanced technologies obtained from technology cooperation. Therefore, the technology cooperation of small and medium sized firms can be thought as their specific resource. Due to the importance of technology cooperation, many previous studies paid an attention on its positive effect. Unlike the related studies, this study examined the link among uncertainty of technology environment, relationship characteristics(such as degree of technology cooperation and influential strategy), and relationship tie. The empirical results are reported as follows: Firstly, uncertainty of technology environment positively affected on degree of technology cooperation. Secondly, degree of technology cooperation positively affected on uncoercive influential strategies of both own firm and partner firm. Thirdly, degree of technology cooperation and uncoercive influential strategy of own firm have positive effects on relationship tie while uncoercive influential strategy of partner firm does not. The positive effect of uncoercive influential strategy of own firm means the importance of strategic countermeasures to promote relationship tie in technology cooperation of both own firm and partner firm.