• Annals of Clinical Neurophysiology
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• 제10권1호
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• pp.33-37
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• 2008

Diabetic polyneuropathy (DPN) is the most common form of diabetic neuropathy, and causes a significant morbidity with an impact on the quality of life in the patients with diabetes. Since DPN frequently induces foot deformity and ulceration, which finally leads to foot amputation, the early detection and treatment is very important for the prevention of a permanent structural change. In the early stage of DPN, the diagnostic methods which can evaluate the function or structure of small nerve fibers should be employed because small nerve fibers are first involved in the course of DPN. However, the nerve conduction study cannot reflect the function of the small nerve fibers, and thus, has a definite limitation in the early diagnosis of DPN. For the early detection of DPN, electrodiagnostic data should be interpreted on a clinical context, along with the careful evaluation of the small nerve fiber functions using the tests such as the analysis of intraepidermal nerve fiber density.

• The Journal of Korean Physical Therapy
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• 제18권4호
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• pp.19-26
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• 2006

Purpose: This study aimed the effects of percutaneous electric nerve stimulation (PENS) applied to different parts of the streptozotocin-induced diabetic rats on the change of glucose and nerve. Methods: rats (ten weeks old) were selected as the subjects; the normal group was five rats, and the diabetes induction group II, III and IV were five rats, respectively, which were randomly sampled from the twenty-five streptozotocin-administered rats with more than $240\;d{\ell}/m{\ell}$ of blood sugar. For PENS, electric current with 2 Hz of stimulation frequency and $200\;{\mu}s$ of pulse duration was applied to the subjects for fifteen minutes a day, six days a week, for three weeks. Calculation of glucose and weight, and nerve conduction test were conducted forty-eight hours and three weeks after streptozotocin administration, respectively. Results: As for change of glucose and weight, the group III with stimulation to the acupoints and the group IV with stimulation to non-acupoints showed significant differences from the control group II (p<0.05). As for MNCV (motor nerve conduction velocity), the group III with stimulation to the acupoints showed significant differences from the group IV with stimulation to non-acupoints and the control group II (p<0.05). Conclusion: PENS had the effects of inhibiting increase of glucose, change of weight and decrease of nerve conductive function between the distal and proximal ends of the peripheral nerve in the STZ-induced diabetic rats.

• The Journal of Korean Physical Therapy
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• 제22권6호
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• pp.71-76
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• 2010

Purpose: The purpose of this study was to examine changes in autonomic nerve responses after low-frequency transcutaneous electrical nerve stimulation (TENS). Methods: Research subjects were 24 students who attend University. Subjects were divided into two groups: 1 = a low intensity group; 2 = a high intensity group. Electrodes were attached to the forearm of the dominant arm and electrical stimuli were administered for 15 minutes. Outcome measures were skin conduction velocity, skin temperature, blood flow, and pulse frequency, each of which was measured a total of 4 times. The data were analyzed using a repeated measures ANOVA. Results: In changes in conduction velocity, the main effect of time variation (in black) was statistically significant. The interaction between time and group main effects was not statistically significant; nor was the difference between the groups. Results showed that skin conduction velocity changed without any relation to group. Conclusions: Low frequency TENS selectively increases skin conduction velocity, which may be helpful for activating sudomotor function regardless of intensity.

• Annals of Clinical Neurophysiology
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• 제2권2호
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• pp.89-94
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• 2000

Purpose : Carpal tunnel syndrome (CTS) is a disorder of median nerve at wrist. It is usually diagnosed through clinical manifestation and nerve conduction study (NCS). However, sometimes, NCS does not provide a reliable evidence to reach the diagnosis. Thus, authors performed this study to determine whether NCS was correlated with specific parameters measured on magnetic resonance imaging (MRI) which might become a potential complemental diagnostic tool. Methods : We performed MRI in 34 wrists of 18 patients with clinical manifestations of CTS and pathologic nerve conduction values and analyzed them at levels of the distal radioulnar joint, pisiform and hook of hamate, Results : Increase in the cross-sectional area of the median nerve at the pisiform level and flattening, increased signal intensity, and contrast enhancement of the median nerve at levels of the pisiform and hook of hamate were statistically significant. Change in cross sectional areas between the distal radioulnar joint and hamate and the signal intensities at levels of pisiform and hamate were well correlated with the median nerve conduction velocity. Conclusions : Characteristic MRI findings in CTS reported previously were well demonstrated and some of MRI parameters are well correlated with nerve conduction study. MRI, despite cost, may help in evaluating CTS.

• Annals of Clinical Neurophysiology
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• 제10권1호
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• pp.25-28
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• 2008

Diabetic polyneuropathy (DPN) is the most frequently encountered form of neuropathy in diabetic patients, and it either relentlessly progresses or remains relatively stable for many years, not showing any trend towards improvement. From this point of view, early detection of DPN is very important to prevent the irreversible change of the peripheral nerve from diabetic insults. Although a number of clinical symptoms and/or deficit scales have been developed for clinical or research purposes, nerve conduction study (NCS) has been known one of the most objective and sensitive tools to detect peripheral nerve dysfunctions in diabetic patients. NCS, however, also have several shortcomings. The next two consecutive articles will focus on debates about diagnostic usefulness of NCS and on recent updates of other diagnostic tests including quantitative sensory testings and skin biopsy in the field of diabetic polyneuropathy.

• The Journal of Korean Physical Therapy
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• 제12권1호
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• pp.49-56
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• 2000

The purpose of this study was to investigate the influnce of afferent stimuli, transcutaneous electrical nerve stimulation and ultra sound, on the electrdiagnostic study of normal subjects. Electrodiagnostic study was performed before and after the application of afferent stimulation of the right popliteal fossa on 18 healthy female volunteers. After the transcutaneous electrical nerve stimulation, there is no significantly change of latencies and amplitudes of SEP, H-reflex, peroneal nerve F-wave, and sensory nerve conduction. After the ultra sound, there is no significantly change of latencies and amplitudes of SEP, H-reflex, peroneal nerve F-wave, and sensory nerve conduction. Tibial nope F-wave and motor nerve shows prolonged latency after TENS and US (p<0.01). Ultrasound may have a similar mechanism of action compared to transcutaneous electrical nerve stimulation by having localized inhibitory effects of the peripheral nerve. However, further investigation is needed to assess their mechanism of action and the precise relevance of stimulation modality.

• 대한치과마취과학회지
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• 제5권2호
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• pp.112-116
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• 2005

Facial nerve paralysis following delayed complication after trauma was rare and hard to find reason After symptom of facial nerve paralysis was found, careful clinical and neuropathic investigation needed through electromyography and nerve conduction velocity. It is necessery to Hewing that functional degenaration of nerve conduction was irresible or not. It is important to determine if palsy is already present alter trauma or some later time because origin of viral infection or temperature change may possible.

• Restorative Dentistry and Endodontics
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• 제15권1호
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• pp.1-15
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• 1990

The aim of this study was to investigate the effect of dental therapeutic agent on conduction velocity and threshold current of intradental A- and C-fibers in the cat. Inferior alveolar nerve of cat anesthetized with sodium pentobarbital was exposed and dissected until response of functional single pulp nerve until could be evoked by monopolar electrical stimulation of the crown of the lower left canine teeth. 10ms rectangular pulse was used to determine the threshold current and 1ms rectangular pulse was used to determine conduction velocity. After application of calcium chloride (1, 2, 6M), calcium hydroxide mixed with saline, potassium chloride (0.2, 0.8, 1.6M), eugenol, zinc oxide eugenol to the cavity on the labial surface, conduction velocity and threshold current of single pulp nerve unit were compared with the control. In 10 cats, 24 $A{\delta}$- and 11 C- pulp nerve units were recorded. The mean conduction velocities of $A{\delta}$- and C-fibers were 7.5m/sec (SD=5.8) and 1.2m/sec (SD=0.4), respectively. The mean threshold current was $12.3{\mu}A$ (SD=5.3) for $A{\delta}$-fibers and $24.9{\mu}A$ (SD=8.1) for C-fibers. 1, 2, 6M calcium chloride caused decrease of conduction velocity and remarkable increase of threshold current in $A{\delta}$- and C-fibers. The effect of calcium hydroxide mixed with saline was similar but smaller than calcium chloride solution. 0.2M potassium chloride had insignificant effect. In 0.8M potassium chloride, the threshold current was increased although conduction velocity was not affected. In 1.6M potassium chloride, the threshold current was increased and the conduction velocity was slowed down. Spontaneous activity was recorded frequently for first 5 min but gradually reduced both in $A{\delta}$- and C-fibers. Eugenol had irreversible effect on pulp nerve in that initially there were not certain changes in the conduction velocity and threshold current of $A{\delta}$- and C-fibers, but the responses to electrical stimulation were abruptly disappeared after sustained application and were not recovered. Contrary to eugenol, zinc oxide eugenol did not caused significant increase of the threhold current and caused time dependent decrease of the conduction velocity, and did not show any irreversible change.

• Journal of Oral Medicine and Pain
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• 제30권4호
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• pp.447-455
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• 2005

이 연구의 목적은 하악 이공부에 Nd:YAG 레이저 조사시 통증의 전달과 관련하여 감각신경전도 변화에 영향을 미치는지 조사하는 것이다. 각각 10 Hz와 20 Hz에 100 mJ/pulse의 조건으로 Nd:YAG 레이저를 하악 이공부에 비접촉식으로 5분간 조사하였다. 조사부위는 하악 이공부의 30 mm 지름을 가지는 원으로 설정하였고 조사부와 레이저 팁사이의 거리는 10 mm로 유지하여 원을 그리듯 움직이며 조사하였다. 이때의 출력밀도는 각각 $212\;mW/cm^2$과 $424\;mW/cm^2$이었다. Nd:YAG 레이저 조사 전과 후의 감각신경전도는 $Neurometer^{(R)}$ CPT/C를 이용하여 평가하였다. 그 결과 레이저 조사 전과 후 이공부에서의 전류인지역치(CPT)와 통증내성역치(PTT)를 얻었으며 통계처리를 거쳐 다음의 결과를 얻었다. 1. 2 W, 20 Hz 조건과 1 W, 10 Hz 조건으로 Nd:YAG 레이저를 조사한 경우 레이저 조사 전과 조사 후의 유의한 전류인지역치의 차이는 없었다. 2. 2 W, 20 Hz 조건과 1 W, 10 Hz 조건으로 Nd:YAG 레이저를 조사한 경우 레이저 조사 전과 조사 후의 유의한 통증내성역치의 차이는 없었다. 3. 1 W, 10 Hz 조건과 2 W, 20 Hz 조건으로 Nd:YAG 레이저를 조사하였을 때 두 군 사이 전류인지역치와 통증내성역치의 유의한 차이는 없었다. 따라서 우리는 하악 이공부에 Nd:YAG 레이저 조사가 이신경의 감각신경전도에 유의한 변화를 보이지 않음을 확인하였다.

• Restorative Dentistry and Endodontics
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• 제17권1호
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• pp.22-35
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• 1992

The aim of this study was to investigate the effect of herbal organic extracts on the pain response provoked by noxious stimuli on dental nerve and the peripheral nerve conduction. Cats (2-2.5Kg regardless of sex) that were chosen as experimental animals were classified into control group, Asiasari radix application group and Zingiberis rhizoma application group. They were anesthetized with ${\alpha}$-chloralose, then anterior belly of digastric muscle of both sides were exposed and wire electrodes were inserted for recording of Electromyogram (EMG). Cavities were prepared on canines until pulp of the teeth were exposed. And after the drugs solubilized for 2% and 4% concentration (W/V) in vehicle were applied, their effects were compared through the recording of EMG immediately after drug application, 30 minutes, 60 minutes, 120 minutes and 5 days after, respectively. And after both inferior alveolar nerves were exposed, 4% organic extracts of Zingiberis rhizoma and Asiasari radix were applied for 30 minutes then the change of jaw opening reflex provoked by noxious stimuli on pulpal nerves were observed immediately after washing out, at 30, 60 and 90 minutes after drug had been washed out. After saphenous nerve of both sides were exposed, one side of nerve was used for vehicle application and the other side was used for drug application for 30 minutes. Then conduction of action potential of A-${\delta}$ and C-fiders of saphenous nerves, which have changed with time, was recorded. With analysis of these records, the following results were obtained: 1. Organic extract of Zingiberis rhizoma (2% or 4% concentration) greatly suppressed EMG of digastric muscle provoked by noxious stimuli on pulpal nerve at five days after application, the suppressive: effect was greater than that of organic extract of Asiasari radix. 2. Organic extract of Asiasari radix (2% or 4% concentration) suppressed jaw opening reflex provoked by noxious stimuli on pulpal nerve, at 5 days after drug application. 3. Organic extract of Zingiberis rhizoma and Asiasari radix (immediately after 30 minutes application) suppressed neural conduction of A-${\delta}$ and C-fibers, the suppressive effect was greater on A-${\delta}$ fibers than on C-fibers. 4. Jaw opening reflex provoked by noxious stimuli on pulpal nerve in inferior alveolar nerve was greatly suppressed 30 minutes after drug application, this effect was greater by Zingiberis rhizoma than by Asiasari radix.