• Journal of Chest Surgery
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• 제37권9호
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• pp.809-812
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• 2004

흉벽에 발생하는 전이성 악성 종양은 드문 질환이며 주위 장기로부터 전이되는 경우가 대부분으로 유방, 폐, 흉막, 그리고 종격동 등으로부터 주로 전이되는 것으로 알려져 있다. 특히 흉부가 아닌 먼장기로부터 전이되는 경우는 더욱 드문 것으로 알려져 있고 원발성 악성 종양이 없이 흉벽 전이에 의해 발현되는 예는 몇몇의 보고만이 있을 뿐이다. 환자는 51세 남자로 전흉벽 좌상부에 촉지되는 종괴로 절제 수술을 시행 후 전이성 간세포암종으로 진단 받았고 당시 검사상 간에 원발성 간세포암종의 증거는 없는 상태였다. 이에 원발성 종양의 증거 없이 간세포암이 흉벽으로 전이된 예를 치험하였기에 보고하는 바이다.

• Radiation Oncology Journal
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• 제31권4호
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• pp.267-272
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• 2013

Although significant advances in the treatment of intrahepatic lesions, it is reported that the prognosis for patients with hepatocellular carcinoma (HCC) who have extrahepatic metastasis remains poor. We report a patient with lung, liver, brain, bone and subcutaneous metastasis from HCC who has survived more than 7 years maintaining relatively good performance status as a result of repeated therapies. A 55-year-old male patient with HCC underwent right lobectomy of the liver and cholecystectomy in September 2006. He received wedge resection for lung metastasis twice (July 2009, January 2011) and Gamma Knife stereotactic radiosurgery for brain metastasis (April 2011). Over the last 3 years, he has developed metastasis in subcutaneous tissues, muscle, and bone with pain. He has undergone 7 courses of radiotherapies for subcutaneous tissues, muscle, and bone metastasis and been prescribed sorafenib and he is still capable of all self-care.

• Journal of Korean Neurosurgical Society
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• 제60권1호
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• pp.94-97
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• 2017

Gastrointestinal stromal tumors (GISTs) are rare, but are the most common mesenchymal neoplasm of the gastrointestinal tract. The most common sites of metastasis are liver and peritoneum, while bone metastasis is rare. We report on a patient with skull metastasis after seven years of treatment with imatinib for metastatic GIST. She underwent metastasectomy consisting of craniectomy with excision of the mass, and cranioplasty and continued treatment with imatinib and sunitinib, without evidence of cranial recurrence. She died of pneumonia sepsis one year after metastasectomy. Skull metastasis of GIST is a very rare presentation, and an aggressive multidisciplinary approach should be considered whenever possible.

• Journal of Chest Surgery
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• 제28권12호
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• pp.1155-1159
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• 1995

Differentiated thyroid carcinoma is a slow growing tumor with relative good prognosis. But locally advanced thyroid cancer with T4 or N1b is difficult to manage. Between June 1988 and April 1995, we resected 8 advanced thyroid cancers trans-sternally. All patients had direct mediastinal extension [T4 or mediastinal lymph node metastasis [N1b with airway obstruction or dysphagia. We operated all the patients by partial or total sternotomy for mediastinal dissection along with thyroidectomy and radical neck dissection. There were some acceptable morbidities but no operative mortality. Postoperative radioactive iodine therapy was followed without side effects. Follow-up survival period was between 11 months to 81 months with 2 late mortalities [17 month, 30 month . Although definite benefit for routine mediastinal dissection in thyroid cancer has not been established, in locally advanced cases impending airway obstruction or dysphagia who have questionable effect by radioactive iodine therapy alone, aggressive mediastinal mass dissection including lymph node metastasis has the significant role to prevent the patients from suffocation & dysphagia, and to enhance the effect of followed radioactive iodine tharapy.

• Journal of Chest Surgery
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• 제43권1호
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• pp.117-119
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• 2010

맥락막 흑색종은 성인에서 가장 빈번한 안구 내 종양이다. 간, 폐, 뼈로 전이를 잘하며 그 예후는 나쁜 것으로 알려져 있다. 본 논문에서 저자들은 늑골 및 기관지에 전이된 맥락막 흑색종에 대하여 수술적 절제를 하였으며 이를 보고하고자 한다.

• Journal of Chest Surgery
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• 제32권9호
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• pp.840-843
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• 1999

저자는 심장의 우심실내에 입구와 출구를 막는 커다란 전이성 흑색종 1례를 수술치험하였기에 보고한다. 49세 여자환자로 호흡곤란과 전신부종의 증상을 보였다. 심초음파상 우심실내에 커다란 종괴와 심낭액을 보 였다. 심폐 체외순환후 심실내 종괴를 제거하였고, 악성 흑색종으로 판명되었다. 환자는 수술후 30일 현재 양호하다.

• Journal of Chest Surgery
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• 제32권10호
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• pp.962-965
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• 1999

Carcinosarcoma of the esophagus have an interesting pathologic feature of admixture of carcinomatous and sarcomatous lesion and accounts for 0.5∼1.5% of all esophageal neoplasm. Generally, it has been reported that these have better prognosis than the squamous cell carcinoma. We have experienced two cases of carcinosarcoma occurring at the mid-esophagus. In both two cases, Ivor Lewis operation was performed and lymph node metastasis was absent. The pathologic diagnosis was confirmed as carcinosarcoma. Postoperative course was uneventful and the patients have been followed up for 3 months and 3 years, respectively, without any problems. We report these cases with a brief review of the literatures.

• Journal of Gastric Cancer
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• 제14권3호
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• pp.215-219
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• 2014

Distant metastasis from papillary thyroid carcinoma (PTC), particularly from papillary thyroid microcarcinoma, is rare. We present a case of perigastric lymph node metastasis from PTC in a patient with early gastric cancer and breast cancer. During post-surgical follow-up for breast cancer, a 56-year-old woman was diagnosed incidentally with early gastric cancer and synchronous left thyroid cancer. Therefore, laparoscopic distal gastrectomy with lymph node dissection and left thyroidectomy were performed. On the basis of the pathologic findings of the surgical specimens, the patient was diagnosed to have papillary thyroid microcarcinoma with perigastric lymph node metastasis and early gastric cancer with mucosal invasion. Finally, on the basis of immunohistochemical staining with galectin-3, the diagnosis of perigastric lymph node metastasis from PTC was made. When a patient has multiple primary malignancies with lymph node metastasis, careful pathologic examination of the surgical specimen is necessary; immunohistochemical staining may be helpful in determining the primary origin of lymph node metastasis.

• Journal of Gastric Cancer
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• 제13권3호
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• pp.192-195
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• 2013

Gastrointestinal stromal tumor is a rare tumor which arises from the whole gastrointestinal tracts and most of it is detected in the stomach. It is uncommon with small intestine originated gastrointestinal stromal tumor and more uncommon with lymphatic metastasis. We experienced an unusual case of the small bowel gastrointestinal stromal tumor during experimental autopsy. Two primary tumors with central necrosis were detected in the ileum. The sizes of each tumor were $6.1{\times}3.4{\times}4.0$ cm and $3.7{\times}4.2{\times}3.2$ cm. There was extensive lymphatic metastasis on the greater omentum and mesenteric, iliac lymph nodes were also involved. With histologic findings, the eosinophilic spindle cells were densely distributed. Immunohistochemical findings were CD117 (-), CD34 (+), desmin (-), and S-100 protein (-). Therefore, we diagnosed the tumors as small bowel gastrointestinal stromal tumors with broad lymph node mestasis.

• Journal of Chest Surgery
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• 제37권11호
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• pp.933-936
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• 2004

정맥내 평활근종증은 자궁근육이나 혈관벽에서 발생한 평활근종이 정맥로를 통해 확장되어, 조직학적으로는 양성이나 임상적으로는 악성 경과를 취하는 매우 드문 질환이다. 종양은 대부분 정맥을 통로로 하공정맥, 우심방, 우심실, 심지어 폐동맥까지 확장되어 우심장의 폐쇄를 일으키면서 증상을 나타내는 것으로 되어 있으나, 매우 드물게 폐전이도 일으키는 것으로 보고되고 있다. 자궁에서 발생한 정맥내 평활근종이 우심실까지 확장되어 우심 폐쇄의 증상과 폐전이를 일으킨 53세의 여자 환자를 수술 치험하였기에 문헌고찰과 함께 보고한다.