• Journal of the Korean Society of Environmental Restoration Technology
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• v.13 no.3
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• pp.36-45
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• 2010

To analyze the relationship between climatic factors (monthly mean temperature and total precipitation) and tree-ring growths of Quercus mongolica Fischer (Mongolian oak) with different topographic sites in Mt. Worak, more than 10 trees were selected from each of seven stands. Two cores from each tree were measured for ring width. After crossdating, each ring-width series was double standardized by fitting first a negative exponential or straight regression line and secondly a 60-year cubic spline. Seven stands were categorized in two groups using cluster analysis for tree-ring index patterns. Cluster I (four stands) was located in higher elevation (550-812 m) with aspects of east, west and northwest, and cluster II (three stands) was located in rather lower election (330-628 m) with aspects of north and northwest. The aspects of two clusters were not significantly different. Response-function analysis showed a significant positive response to March precipitation for both clusters. It indicates that moisture supply during early spring season is important to radial growth because the cambial growths of ring-porous species, such as Mongolian oak, start before leaf growth. Cluster II showed a positive response to the precipitation of middle and late growing season, too.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.18 no.3
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• pp.266-270
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• 1985

In order to obtain the fishing possibility by acoustic, the two fishes, Lateolabrax japonicus, Mugil cephalus, were bred in a water tank. The feeding sounds from the fishes and the artificial sounds were recorded by a hydrophone and then the frequency and the sound pressure level of the sounds recorded were analyzed by the digital frequency analyzer. These sounds were edited in two manners of which one is emitted for 10 seconds and paused for 10 seconds continuously and the other is emitted for 20 seconds and paused for 20 seconds also. These edited sounds were emitted again into the tank and the respose of fisher were observed. Lateolebrax japonicus showed a positive response and Mugil cephalus responsed a little positively to the emitted feeding sound, The fishes seemed to show a positive response only in emitting a moderate pressure level of feeding sound. Lateolabrax japonicus and Mugil cephalus showed negative response to the emitted artificial sound. It was most effective to increase the sound pressure level that the fishes went away from the sound source to the emitted artificial sound.

• Journal of the Korean Society of Safety
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• v.21 no.6 s.78
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• pp.74-81
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• 2006

Probabilistic Risk Assessment considering statistically random variables is performed for the preliminary design of a Arch Bridge. Component reliabilities of girders have been evaluated using the response surfaces of the design variables at the selected critical sections based on the maximum shear and negative moment locations. Response Surface Method(RSM) is successfully applied for reliability analyses for this relatively small probability of failure of the complex structure, which is hard to be obtained by Monte-Carlo Simulations or by First Order Second Moment Method that can not easily calculate the derivative terms of implicit limit state functions. For the analysis of system reliability, parallel resistance system composed of girders is changed into parallel series connection system. The upper and lower probabilities of failure for the structural system have been evaluated and compared with the suggested prediction method for the combination of failure modes. The suggested prediction method for the combination of failure modes reveals the unexpected combinations of element failures in significantly reduced time and efforts compared with the previous permutation method or system reliability analysis method.

• Biomolecules & Therapeutics
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• v.6 no.3
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• pp.276-282
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• 1998

Retinoids regulate a wide variety of biological processes such as cellular proliferation and differentiation in many cell types. They have also shown to stimulate replication of several viruses including human cytomegalovirus (CMV). Retinoid signalling pathway involves two distinct subfamilies of nuclear receptors, retinoic acid receptors (RARs) and retinoid X receptors (RXRs) that bind to specific retinoic acid response elements (RAREs) in the promoter regions of retinoid-target genes. Here, we characterized RAREs in the regulatory regions of the CMV and of the hepatitis B vi.us (HBV). The viral RAREs, i.e., CMV-RARE and HBV-RARE, are composed of two consensus RARE half-sites (A/GGGTCA) arranged as a direct repeat separated by 5-bp and 1-bp, respectively. The RAREs were activated by both RAR/RXR heterodimers and RXR homodimers in transient transfection experiments. We also found that COUP-TF$\alpha$ (chicken ovalbumin upstream promoter-transcription factor u) and COUP-TF$\beta$ repressed the retinoid response of the viral elements. Further we demonstrated that previously known retinoid antagonist, SRI 1330, repressed retinoid-induced transactivation of the CMV-RARE. These results implicate Vitamin A, it's nuclear receptors and COUP-TFs as important regulators of the CMV and HBV pathogenesis and the SRl1330 as potential negative modulator of such retinoid-dependent processes.

• Molecules and Cells
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• v.39 no.2
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• pp.163-168
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• 2016

Caffeine has both positive and negative effects on physiological functions in a dose-dependent manner. C. elegans has been used as an animal model to investigate the effects of caffeine on development. Caffeine treatment at a high dose (30 mM) showed detrimental effects and caused early larval arrest. We performed a comparative proteomic analysis to investigate the mode of action of high-dose caffeine treatment in C. elegans and found that the stress response proteins, heat shock protein (HSP)-4 (endoplasmic reticulum [ER] chaperone), HSP-6 (mitochondrial chaperone), and HSP-16 (cytosolic chaperone), were induced and their expression was regulated at the transcriptional level. These findings suggest that high-dose caffeine intake causes a strong stress response and activates all three stress-response pathways in the worms, including the ER-, mitochondrial-, and cytosolic pathways. RNA interference of each hsp gene or in triple combination retarded growth. In addition, caffeine treatment stimulated a food-avoidance behavior (aversion phenotype), which was enhanced by RNAi depletion of the hsp-4 gene. Therefore, up-regulation of hsp genes after caffeine treatment appeared to be the major responses to alleviate stress and protect against developmental arrest.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.11
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• pp.1527-1576
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• 2002

Quick Response based Mass-Customization can be produced and distributed customized goods and services on mass basis in apparel e-business. Because consumers can: t touch and feel the apparel products in e-business, they tend to have the negative buying behavior. The purpose of this study is to investigate the differences of consumer's texture sensibility of apparel products based on marketing channels (on-line/off-line). Two types of questionnaires for on-line and of f-line were used to assess consumer sensibility on apparel fabric. The 8 swatches were selected in regard to the previous literatures. 205 questionnaires for each type (on-line/off-line) were distributed. Statistical devices were t-test, mean and standard deviation with SPSS10.0. The result of this study was showed that there were partially significant differences on consumers' texture sensibility on apparel products between on-line and off-line. Under on-line environment, consumers perceived corduroy as warm, strong, and sandy. taffeta as warm, sandy, and glossy, denim as sandy, and warm, organza as sandy, and thin, satin as sandy, dense, and modern, chiffon as sandy, and flat, velvet as warm, and soft, single jersey as warm, soft, and comfortable. Therefore, apparel firms cooperating based Mass-Customization in e-business have to pay attention to the differences on consumers’ texture sensibility of on-line apparel products from those of off-line.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2007.04a
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• pp.295-300
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• 2007

Probabilistic Risk Assessment considering statistically random variables is performed for the preliminary design of a Arch Bridge. Component reliabilities of girders have been evaluated using the response surfaces of the design variables at the selected critical sections based on the maximum shear and negative moment locations. Response Surface Method (RSM) is successfully applied for reliability analyses for this relatively small probability of failure of the complex structure, which is hard to be obtained by Monte-Carlo Simulations or by First Order Second Moment Method that can not easily calculate the derivative terms of implicit limit state functions. For the analysis of system reliability, parallel resistance system composed of girders is changed into parallel series connection system. The upper and lower probabilities of failure for the structural system have been evaluated and compared with the suggested prediction method for the combination of failure modes. The suggested prediction method for the combination of failure modes reveals the unexpected combinations of element failures in significant]y reduced time and efforts compared with the previous permutation method or system reliability analysis method.

• Journal of Gastric Cancer
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• v.16 no.1
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• pp.1-7
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• 2016

Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is one of the four subtypes of gastric carcinoma (GC), as defined by the novel classification recently proposed by The Cancer Genome Atlas. EBVaGC has several clinicopathological features such as longer survival and higher frequency of lymphoepithelioma-like carcinoma (LELC) and carcinoma with Crohn's disease-like lymphoid reaction that distinguish it from EBV-negative GC. The intensity and pattern of host cellular immune response in GC have been found to significantly correlate with the prognosis of patients with GC, suggesting that immune reaction and tumor microenvironment have critical roles in the progression of GC, and in particular, EBVaGC. Here, we reviewed the cellular and molecular mechanisms underlying prominent immune reactions in patients with EBVaGC. In EBVaGC, deregulation of the expression of immune response-related genes promotes marked intra-or peritumoral immune cell infiltration. The expression of programmed death receptor-ligand 1 is known to be increased in EBVaGC, and therefore, it has been proposed as a favorable prognostic factor for patients with EBVaGC, albeit some data supporting this claim are controversial. Overall, the underlying mechanisms and clinical significance of the host cellular immune response in patients with EBVaGC have not been thoroughly elucidated. Therefore, further research is necessary to better understand the role of tumor microenvironment in EBVaGC.

• Journal of Korean society of Dental Hygiene
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• v.6 no.4
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• pp.361-374
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• 2006

The purpose of this study was to obtain basic data for development of oral health educational program on the control of handicapped children at social welfare facilities. For this research, it was investigated by a survey on the actual condition of dental health of handicapped children, and simultaneously by analyzing the relationships between the realities of child's dental condition and parents and guardian's acknowledgments and managements with regard to the dental health of children. This survey was conducted 135 children and their guardians being 4 social welfare facilities in Ulsan metropolitan city. 1. The average of DT, MT, FT and DMFT index were 1.82, 0.01, 0.98 and 2.84 respectively. 2. Rolling Toothbrushing method was the highest response(58.5%) and 3 times per a day(77.0%). A proxy of toothbrushing was parents(39.2%) and teacher(60.8%). 3. Recognition routes of toothbrushing method were family(13.3%), school(43.7%) and dental chinic(42.2%). 4. The numer of times electromotion tooth brushing was the highest response in more than 4 times per a day. Toothbrushing after eating between meals was higher negative response(50.4%). The number of times visiting dental clinic was the highest response in more than 5 times during a year(51.9%).

• Korean Institute of Interior Design Journal
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• no.9
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• pp.108-115
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• 1996

The relationship between users and physical elements of environmental gives a space special characteristics. The Environment Probabilitism by Altman shows that behavior and environment, both response, effect each other construct their characteristics. People can choose their response consciously or unconsciously during their walking , sitting, standing, talking in their environment. Designing a good place can lead people to the goal that they want and designer intend to get, A good place well designed as an positive place is organised with 3 points(1) User's behavior (2) physical elements in environment (3) meanings produced between behavior and physical elements. In this study the importance of physical elements are focused on. In the place where we can have permeability, variety , legibility, robutness, visual appropriateness, richness, personalisation physically , these characteristics will encourage people to have strong motivation and to choose the most active way . From this perspective the circulation of physically handicapped persons is analyzed into their behavioral environment and their behavioral response. The analysis shows the handicapped in our situation has no environmental right for a man itself ,even they have no street to walk safely. And their response to the environment was very negative. Basically the elements from exterior space to interior space should be guaranteed for everyday according to their behavioral characteristics include handicapped. From this study the result shows that the needs of a person should be considered and accepted as an important design problem for improvement our environment.