• BMB Reports
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• v.35 no.3
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• pp.291-296
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• 2002

Thanatin, a 21-residue peptide, is an inducible insect peptide with a broad range of activity against bacteria and fungi. It has a C-terminal disulfide loop, like the frog skin secretion antimicrobial peptides of the brevinin family. In this study, we tried to find the effect of a number of amino acids between the disulfide bond. Thanatin showed stronger antibacterial activity to Gram negative bacteria than other mutants, except Th1; whereas, the mutant peptides with deletion had higher activity to Gram positive bacteria than thanatin. An increase in the number of amino acid(s) using the alanine residue decreased the antibacterial activity in all of the bacteria. Th1 with deletion of threonine at position 15 ($Thr^{15}$) showed similar antibacterial activity against Gram-negative bacteria, but had higher activity against the Gram positive bacteria. In order to study the structure-function relationship, we measured liposome disruption by the peptides and CD spectra of the peptides. Th1 also showed the highest liposome leaking activity and α-helical propensity in the sodium dodecyl sulfate solution, compared with other peptides. Liposome disruption activity was closely correlated with the anti-Gram positive bacterial activity. All of the peptides showed no hemolytic activity. Th1 was considered to be useful as an antimicrobial peptide with broad spectrum without toxicity.

• Journal of electromagnetic engineering and science
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• v.13 no.4
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• pp.259-262
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• 2013

This paper analyzes the effects of metamaterial slabs with negative permeability when applied to a two-loop wireless power transmission (WPT) system, both in theory and electromagnetic (EM) simulations. The analysis of magnetic flux focusing provided here assumes quasi-magnetostatics or magnetostatics. The slab structures with negative permeability have been realized using the periodically arrayed ring resonators (RRs) at 13.36MHz. Some examples with ideal lossless slabs of -1, -2, and -3 showed a great enhancement of WPT efficiencies when compared with the free space cases. However, practical lossy slabs made of planar copper RRs did not show significant enhancement of WPT efficiencies due to the relatively high losses in the ring resonator (or in the slab consisting of RRs) near the resonant frequency.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.17 no.6
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• pp.31-38
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• 2003

Among mitigation techniques for electric and magnetic field (EMF) from an overhead transmission line a passive loop is a way that can be cheap and easily installed on the existing towers and have a satisfactory effect as well. However current induced in the passive loop causes transmission power loss and the phase imbalance increases since geometrical asymmetry of the transmission lines becomes larger. So in order to evaluate the power loss and the phase imbalance due to a passive loop, this paper represent a 345[kV] 1-circuit flat type transmission line as asymmetrical 3-phase distributed parameter line model where the effect of a passive loop is embedded in the line parameters, and then formulates differential equations. By solving these equations voltages and currents of each phase at receiving end become known. We find out that power losses occur differently at each phase and positive sequence component decreases at receiving end while negative sequence component increase. In general phase imbalance due to a passive loop is slight, but it increases in proportional to the induced current and length of section where the passive loop is installed. Thus the phase imbalance should be included in terms of cost for introducing a passive loop.

• Journal of electromagnetic engineering and science
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• v.3 no.2
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• pp.118-125
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• 2003

This paper presents a 5.8-㎓ oscillator that uses a novel defected ground structure(DGS), which is etched on the metallic ground plane. As the suggested defected ground structure is the structure for mounting an active device, it is the roles of a feedback loop inducing a negative resistance as well as a frequency-selective circuit. Applying the feedback loop between the drain and the gate of a FET device produces precise phase conversion in the feedback loop. The equivalent circuit parameters of the DGS are extracted by using a three-dimensional EM simulation ,md simple circuit analysis method. In order to demonstrate a new DGS oscillator, we designed the oscillator at 5.8-㎓. The experimental results show 4.17 ㏈m output power with over 22 % dc-to-RF power efficiency and - 85.8 ㏈c/Hz phase noise at 100 KHz offset from the fundamental carrier at 5.81 ㎓.

• Journal of Internet Computing and Services
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• v.17 no.4
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• pp.161-172
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• 2016

The following research investigates core factors required for IT professionals to achieve and remain happy on their jobs through dynamic and structural CLD and suggests personal, organizational, and government level (happiness) promoting factors. Researcher adopted the system dynamics methodology which is qualitative research techniques pursue behavior probability by using CLD. It spotlights 6 CLD: job satisfaction, organizational commitment, positive sensitivity, negative sensitivity, amicable relationship, job sustainment intention, in addition to numerous factors that affect them from an integrative perspective. It differentiates itself from one-way relationship focused qualitative research to an advanced mutual and realistic perspective exploratory research.

• BMB Reports
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• v.53 no.7
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• pp.373-378
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• 2020

Phosphorylation of the signaling component by protein kinase often leads to a kinase cascade or feedback loop. 3-Phosphoinositide-dependent kinase 1 (PDK1) signaling pathway diverges into various kinases including Akt and p70 S6 kinase (p70S6k). However, the PDK1 feedback mechanism remains elusive. Here, we demonstrated that UNC-51-like kinase (ULK1), an autophagy initiator kinase downstream of mechanistic target of rapamycin (mTOR), directly phosphorylated PDK1 on serine 389 at the linker region. Furthermore, our data showed that this phosphorylation affected the kinase activity of PDK1 toward downstream substrates. These results suggest a possible negative feedback loop between PDK1 and ULK1.

• Journal of Navigation and Port Research
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• v.38 no.6
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• pp.567-575
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• 2014

In recent times, an obvious strategy in liner shipping markets that has come to the fore is slow steaming. Nowadays, most liner shipping companies have decelerated the voyage speed to 15-18 knots on major routes, and some leading liner shipping companies have a plan to reduce it to below 15 knots. Slow steaming is helpful in reducing the operating cost and the amount of greenhouse-gas emissions on a single vessel with lower fuel consumption. However, it also creates various negative effects such as the opportunity cost, additional fixed costs and an in-transit inventory cost on a loop. Hence, the net operating cost on a loop is changing dynamically due to the changes of voyage speed based on various slow steaming effects. The aim of this study is to analyze the slow steaming effects in the liner shipping, and to find the best voyage speed that minimizes the operating cost on a loop. Moreover, this study suggests the recommendable strategy for liner shipping companies. To achieve the aim of this study, a simulation model has been designed using System Dynamics.

• Journal of Power Electronics
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• v.16 no.5
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• pp.1939-1949
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• 2016

This paper presents an alternative frequency adaptive grid synchronization technique named HDN-FLL, which can accurately extract the fundamental positive- and negative-sequence components and interested harmonics in adverse three-phase grid voltage. The HDN-FLL is based on the harmonic decoupling network (HDN) consisting of multiple first order complex vector filters (FOCVF) with a frequency-locked loop (FLL), which makes the system frequency adaptive. The stability of the proposed FLL is strictly verified to be global asymptotically stable. In addition, the linearization and parameters tuning of the FLL is also discussed. The structure of the HDN has been widely used as a prefilter in grid synchronization techniques. However, the stability of the general HDN is seldom discussed. In this paper, the transfer function expression of the general HDN is deduced and its stability is verified by the root locus method. To show the advantages of the HDN-FLL, a simulation comparison with other gird synchronization methods is carried out. Experimental results verify the excellent performance of the proposed synchronization method.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.7
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• pp.82-88
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• 2014

An available capacitance increasing phase-locked loop(PLL) with two voltage controlled oscillator gains has been proposed. In this paper, the available capacitance of loop filter is increased by using two positive/negative gains of voltage controlled oscillator (VCO). It results in 1/10 reduction in the size of loop filter capacitor. It has been designed with a 1.8V $0.18{\mu}m$ CMOS process. The simulation results show that the proposed PLL has the same phase noise characteristic and a locking time of conventional PLL.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.8
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• pp.28-34
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• 2008

A magnetic field detector as a potential MRI receiver is proposed. The proposed device is composed of SRR(split ring resonator) which is a kind of LC resonator first introduced as a negative permeability material and a simple loop antenna. The proposed device showed similar degree of performance to commercial one with a simpler circuit.