• Transactions of the Korean Society of Mechanical Engineers A
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• v.40 no.8
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• pp.731-736
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• 2016

Three-dimensional (3D) high-aspect-ratio (HAR) microstructures for biomedical applications (e.g., microneedle, microadhesive, etc.) are microfabricated using the hybrid ultraviolet (UV) lithography in which inclined, rotational, and reverse-side UV exposure processes are combined together. The inclined and rotational UV exposure processes are intended to fabricate tapered axisymmetric HAR microstructures; the reverse-side UV exposure process is designed to sharpen the end tip of the microstructures by suppressing the UV reflection on a bottom substrate which is inevitable in conventional UV lithography. Hybrid UV lithography involves fabricating 3D HAR microstructures with an epoxy-based negative photoresist, SU-8, using our customized UV exposure system. The effects of hybrid UV lithography parameters on the geometry of the 3D HAR microstructures (aspect ratio, radius of curvature of the end tip, etc.) are measured. The dependence of the end-tip shape on SU-8 soft-baking condition is also discussed.

• Journal of Korean Neurosurgical Society
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• v.60 no.4
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• pp.417-423
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• 2017

Objective : Repair of sensorial nerve defect is an important issue on peripheric nerve surgery. The aim of the present study was to determine the effects of sensory-motor nerve bridging on the denervated dermatomal area, in rats with sensory nerve defects, using a neural cell adhesion molecule (NCAM). Methods : We compared the efficacy of end-to-side (ETS) coaptation of the tibial nerve for sural nerve defect repair, in 32 Sprague-Dawley rats. Rats were assigned to 1 of 4 groups : group A was the sham operated group, group B rats had sural nerves sectioned and buried in neighboring muscles, group C experienced nerve sectioning and end-to-end (ETE) anastomosis, and group D had sural nerves sectioned and ETS anastomosis was performed using atibial nerve bridge. Neurological evaluation included the skin pinch test and histological evaluation was performed by assessing NCAM expression in nerve terminals. Results : Rats in the denervated group yielded negative results for the skin pinch tests, while animals in the surgical intervention groups (group C and D) demonstrated positive results. As predicted, there were no positively stained skin specimens in the denervated group (group B); however, the surgery groups demonstrated significant staining. NCAM expression was also significantly higher in the surgery groups. However, the mean NCAM values were not significantly different between group C and group D. Conclusion : Previous research indicates that ETE nerve repair is the gold standard for peripheral nerve defect repair. However, ETS repair is an effective alternative method in cases of sensorial nerve defect when ETE repair is not possible.

• Journal of the Korean Society of Safety
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• v.21 no.5 s.77
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• pp.28-33
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• 2006

The rapidly advanced industrial society takes advantage of high-technology, but it also suffered from the side effects such as various diseases by contamination. Of these problems, air pollution is considered as the most important problem nowadays. Air contamination is not only limited outdoors, but it also causes more serious effect in our indoor air environment. Depending on the notion that indoor air effects physical health seriously, the needs of the air cleaner is more earnest. Therefore, the main purpose of this study is to develop the air cleaner to meet the standard and get rid of poisonous and harmful material from the atmosphere by using a Corona Discharge. According to the purpose of this study, We set the negative ion generator, the UV, $TiO_{2}$ optical catalyzer, the electrical dust collector and the air filter in series order. It emits a lot of negative ions. We use these ions to purify harmful factors and contaminated materials. We collect the dust using static power that comes from the discharge of corona. At the same time, we try to develop the air cleaner to keep the air quality to meet the standard and kill the various viruses using UV LED and $TiO_{2}$ optical catalyzer. In this study, we use the UV LED that is smaller and efficient than a existing UV lamp. What is more, the UV LED has a features that a stabilizer occupying much space is not needed any more.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2141-2144
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• 2016

Background: Many cancer patients still experience pain worldwide. There are many barriers for effective control of cancer pain and many of these are related to health care providers. There is a need for further investigation of these barriers. The aim of this study was to investigate nurse-related barriers to control of cancer pain among Iranian nurses. Materials and Methods: In this descriptive study 49 nurses from two hospitals affiliated to Tabriz and Ardebil Universities of Medical Sciences participated using a census sampling method. A demographic and profession related checklist and Barriers Questionnaire II (BQ-II) were used for data collection. Results: The results showed negative attitudes of participants regarding control of cancer pain. Participants believed that cancer pain medications do not manage cancer pain at acceptable levels; patients may become addicted by using these drugs; cancer pain medications have many uncontrollable effects; and controlling cancer pain may distract the physicians from treating disease. Conclusions: Iranian nurses have negative attitudes toward pain control in cancer patients especially about effectiveness of pain medication and their side effects. Educational intervention to reduce these misconceptions is needed.

• Parasites, Hosts and Diseases
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• v.61 no.4
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• pp.405-417
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• 2023

Chagas disease, caused by Trypanosoma cruzi parasite, is a significant but neglected tropical public health issue in Latin America due to the diversity of its genotypes and pathogenic profiles. This complexity is compounded by the adverse effects of current treatments, underscoring the need for new therapeutic options that employ medicinal plant extracts without negative side effects. Our research aimed to evaluate the trypanocidal activity of Bidens pilosa fractions against epimastigote and trypomastigote stages of T. cruzi, specifically targeting the Brener and Nuevo León strains-the latter isolated from Triatoma gerstaeckeri in General Terán, Nuevo León, México. We processed the plant's aerial parts (stems, leaves, and flowers) to obtain a methanolic extract (Bp-mOH) and fractions with varying solvent polarities. These preparations inhibited more than 90% of growth at concentrations as low as 800 ㎍/ml for both parasite stages. The median lethal concentration (LC₅₀) values for the Bp-mOH extract and its fractions were below 500 ㎍/ml. Tests for cytotoxicity using Artemia salina and Vero cells and hemolytic activity assays for the extract and its fractions yielded negative results. The methanol fraction (BPFC3MOH1) exhibited superior inhibitory activity. Its functional groups, identified as phenols, enols, alkaloids, carbohydrates, and proteins, include compounds such as 2-hydroxy-3-methylbenzaldehyde (50.9%), pentadecyl prop-2-enoate (22.1%), and linalool (15.4%). Eight compounds were identified, with a match confirmed by the National Institute of Standards and Technology (NIST-MS) software through mass spectrometry analysis.

• Korean Journal of Clinical Laboratory Science
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• v.46 no.1
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• pp.12-16
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• 2014

Tetanus has high lethality and can cause serious complication, so it is very important to have a quick and exact checkup and treatment. In this study, we conducted a study about clinical characteristics and types of tetanus patients in Daegu Emergency Medical Center and we studied possibility of Tetanos Quick Stick (TQS) as a selective check up to treat tentanus by comparing the results of local checkup kit measured from tetanus quick stick developed to check up tetanus antibody titer and results measured from ELISA (Enzyme-Linked Immunosorbent Assay). The result of the study showed that tetanus happens more to males, and by looking at season, tetanus happened most in summer (from June-August) as 19 cases (45.3%), and when patients come to the emergency medical center, the diagnosis name was electrolyte imbalance 14 cases (33.3%), peripheral nerve 11 cases (26.2%), Meningitis 8 cases (19.0%), drug addiction 7 cases (16.7%), and the patients who are diagnosed as tetanus at the beginning of hospitalization was 2 cases (4.8%). The result of TQS usefulness by comparing with ELISA, in TQS, 42 people was positive and 478 people was negative. it was positive when the result was over 0.1 IU/mL, 48 people was ELISA positive while 472 people was negative. TQS checkup has accuracy of 98%, sensitivity of 83.3%, specificity of 99.5%, positive predictability of 95.2% and negative predictability of 98.3%. The evaluation of current immunity statuses of tetanus patients is available for TQS checkup, and it has an advantage of preventing side effects coming from the injection of unnecessary vaccine and immunoglobulin, and it is thought that it can give help to emergency checkup and treatment at the beginning.

• Journal of Fashion Business
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• v.16 no.4
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• pp.107-122
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• 2012

This thesis takes it an aim to analyze and compare the visual images which results from attaching the voluminous changes of the waist gathering to the basic Sarrouel pants, one of the Islamic costume, and also from the three body type influenced by these changes. The method of the investigation was to select basic designs of the Sarrouel pants, then the three pieces of the experimental clothes called pattern 1(50%), pattern 2(100%), and pattern 3(150%) were made respectively. The 3 types of the adult women were selected as models in a way to represent the S(S1), M(S2), L(S3) the female body indices of the K. S. The models wearing the 3 types of experimental clothes were taken pictures from the front, side and back, which the pictures were used for the evaluations for the visual effects. For the evaluation, the questionaire from 12 to 18, associated with the body types and images respectively were completed and collected in an investigative way. The visual effects by the waist gathering and body size are composed body and image emerged the four factors. Conclusively, the volume of the waist gathering gives a benefit only in terms of the appropriateness in which the voluminous gatherings compensate for the defects of the body type while too much gathering leads to the negative effects. The visual effects from the increased gathering gives the impressions of the more activity with the snugness as it decreases the feminine effects. The evaluation indices like the stiffness or the masculine images might be more or less predominant in this case. This might be ascribed to the fact that the Sarrouel pants were originated from the men's trousers in a real sense.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.05d
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• pp.53-56
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• 2003

Blending effects for generating a pretilt angle in nematic liquid crystal (NLC) with negative dielectric anisotropy on the blended polyimide (PI) of homeotropic and homogeneous alignment surface were studied. Also, we investigated the EO performances for the advanced VA-$\pi$ cell using this homeotropic blended PI surface. A many decrease of tilt angle on the polymer surface to blend homeotropic PI and homogeneous PI with side chain type was measured, and the tilt angle decreased as blended ratio and rubbing strength increase. The blended effects for generating a pretilt angle were clearly observed, and the many decrease of tilt angle can be achieved by using the blended PI surface. The electro-optical (EO) characteristics using the advanced VA-$\pi$ cell using the homeotropic blended PI surface than that of conventional VA cell can be improved. We suggest that the developed advanced VA-$\pi$ cell on a homeotropic blended PI surface is a promising technique for the achievement of a fast response time, and a high contrast ratio.

• Knowledge Management Research
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• v.15 no.4
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• pp.171-187
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• 2014

The social network services (SNS) like Facebook, have gained an enormous amount of popularity. However, side-effects of Facebook usage are occasionally reported such as sense of alienation and cyber-bullying. Among these potential factors threatening to the success of SNS, this research focused on alienation and intends to investigate possible factors that affect SNS alienation and how it affects on SNS attachment and proactive use of SNS. Through extensive literature reviews regarding online and offline alienation, SNS characteristics, and SNS usage, we generated the research model and hypotheses. We surveyed 142 Facebook users and empirically proved that among SNS characteristics, complexity increases SNS alienation, and interactivity and social presence positively affect SNS attachment. Offline alienation, one of the personal attributes, increases both SNS alienation and SNS attachment at the same time while the number of SNS friends have no significant effects. In addition, SNS alienation decreases proactive use of Facebook while SNS attachment increases it. Theoretical and practical implications are discussed based on research findings, and we also suggest future research directions to minimize negative consequences due to SNS users' sense of alienation.

• Journal of Korea Society of Digital Industry and Information Management
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• v.10 no.3
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• pp.285-296
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• 2014

Recently, the use of Smartphones has been widespread and changed our lives positively. Smartphones which are called as PC in the hand and spread general people rapidly are becoming a medium to use generally various functions such as internet, work, multimedia, etc. beyond the simple function of telephone communication in the past. However, the excessive use of Smartphones has also produced many side effects. The purpose of this study is to examine the Smartphone Addiction on Daily Life Impact. This model tests various theoretical research hypotheses relating to Self-Esteem, Enjoyment, Flow, Social Impact, Smartphone Addiction and Daily life impact. The proposed model is analyzed to target 299 University Students and Smart Partial Least Square(PLS) 2.0 have been utilized for deriving the study results. The Result of Hypothesis testing are as follows. First, Self-Esteem negatively influence Smartphone Addiction. Second, Enjoyment, Flow and Social Impact positively influence Smartphone Addiction. Third, Smartphone Addiction positively influence Daily Life impact. This Research makes a basic research for smart phone addiction papers that will be investigated a lot in the future.